Intragastric administration of leucine or isoleucine lowers the blood glucose response to a mixed-nutrient drink by different mechanisms in healthy, lean volunteers
Ullrich, Sina S, Fitzgerald, Penelope Ce, Schober, Gudrun, Steinert, Robert E, Horowitz, Michael, Feinle-Bisset, Christine
Published in The American journal of clinical nutrition (01.11.2016)
Published in The American journal of clinical nutrition (01.11.2016)
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Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats[S]
Schober, Gudrun, Arnold, Myrtha, Birtles, Susan, Buckett, Linda K., Pacheco-López, Gustavo, Turnbull, Andrew V., Langhans, Wolfgang, Mansouri, Abdelhak
Published in Journal of lipid research (01.05.2013)
Published in Journal of lipid research (01.05.2013)
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Sugar Responses of Human Enterochromaffin Cells Depend on Gut Region, Sex, and Body Mass
Lumsden, Amanda L, Martin, Alyce M, Sun, Emily W, Schober, Gudrun, Isaacs, Nicole J, Pezos, Nektaria, Wattchow, David A, de Fontgalland, Dayan, Rabbitt, Philippa, Hollington, Paul, Sposato, Luigi, Due, Steven L, Rayner, Christopher K, Nguyen, Nam Q, Liou, Alice P, Jackson, V Margaret, Young, Richard L, Keating, Damien J
Published in Nutrients (22.01.2019)
Published in Nutrients (22.01.2019)
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A syngeneic inoculation mouse model of endometriosis that develops multiple comorbid visceral and cutaneous pain like behaviours
Maddern, Jessica, Grundy, Luke, Harrington, Andrea, Schober, Gudrun, Castro, Joel, Brierley, Stuart M
Published in Pain (Amsterdam) (01.08.2022)
Published in Pain (Amsterdam) (01.08.2022)
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Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H 1 receptor and TRPV1
Grundy, Luke, Caldwell, Ashlee, Garcia Caraballo, Sonia, Erickson, Andelain, Schober, Gudrun, Castro, Joel, Harrington, Andrea M, Brierley, Stuart M
Published in American journal of physiology. Renal physiology (01.02.2020)
Published in American journal of physiology. Renal physiology (01.02.2020)
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Journal Article
Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H1 receptor and TRPV1
Grundy, Luke, Caldwell, Ashlee, Caraballo, Sonia Garcia, Erickson, Andelain, Schober, Gudrun, Castro, Joel, Harrington, Andrea M, Brierley, Stuart M
Published in American journal of physiology. Renal physiology (01.02.2020)
Published in American journal of physiology. Renal physiology (01.02.2020)
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EP1239: DESCENDING PAIN MODULATION OF COLORECTAL NOCICEPTIVE PROCESSING IN THE SPINAL CORD IS IMBALANCED IN A MOUSE MODEL OF POST-COLITIS CHRONIC VISCERAL HYPERSENSITIVITY AND IS REDUCED BY CHRONIC ORAL LINACLOTIDE TREATMENT
Harrington, Andrea, Schober, Gudrun, Maddern, Jessica, Wang, Qingqing, Hannig, Gerhard, Brierley, Stuart
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2022)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2022)
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Olorinab (APD371), a peripherally acting, highly selective, full agonist of the cannabinoid receptor 2, reduces colitis-induced acute and chronic visceral hypersensitivity in rodents
Castro, Joel, Garcia-Caraballo, Sonia, Maddern, Jessica, Schober, Gudrun, Lumsden, Amanda, Harrington, Andrea, Schmiel, Shirdi, Lindstrom, Beatriz, Adams, John, Brierley, Stuart M
Published in Pain (Amsterdam) (01.01.2022)
Published in Pain (Amsterdam) (01.01.2022)
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Gut enterochromaffin cells drive visceral pain and anxiety
Bayrer, James R, Castro, Joel, Venkataraman, Archana, Touhara, Kouki K, Rossen, Nathan D, Morrie, Ryan D, Maddern, Jessica, Hendry, Aenea, Braverman, Kristina N, Garcia-Caraballo, Sonia, Schober, Gudrun, Brizuela, Mariana, Castro Navarro, Fernanda M, Bueno-Silva, Carla, Ingraham, Holly A, Brierley, Stuart M, Julius, David
Published in Nature (London) (06.04.2023)
Published in Nature (London) (06.04.2023)
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A spider-venom peptide with multitarget activity on sodium and calcium channels alleviates chronic visceral pain in a model of irritable bowel syndrome
Cardoso, Fernanda C, Castro, Joel, Grundy, Luke, Schober, Gudrun, Garcia-Caraballo, Sonia, Zhao, Tianjiao, Herzig, Volker, King, Glenn F, Brierley, Stuart M, Lewis, Richard J
Published in Pain (Amsterdam) (01.02.2021)
Published in Pain (Amsterdam) (01.02.2021)
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Sa1078 CANNABINOID RECEPTOR EXPRESSION AND THE EFFECT OF OLORINAB, A PERIPHERALLY ACTING, HIGHLY SELECTIVE, FULL AGONIST OF THE CANNABINOID RECEPTOR 2 (CB2), IN RODENTS WITH COLITIS AND CHRONIC VISCERAL HYPERSENSITIVITY
Castro, Joel, Maddern, Jessica, Garcia-Caraballo, Sonia, Schober, Gudrun, Lindstrom, Beatriz, Schmiel, Shirdi, Brierley, Stuart
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2020)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2020)
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A mouse model of endometriosis that displays vaginal, colon, cutaneous, and bladder sensory comorbidities
Castro, Joel, Maddern, Jessica, Grundy, Luke, Manavis, Jim, Harrington, Andrea M, Schober, Gudrun, Brierley, Stuart M
Published in The FASEB journal (01.04.2021)
Published in The FASEB journal (01.04.2021)
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Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ‑Opioid Receptor for the Treatment of Chronic Abdominal Pain
Muratspahić, Edin, Tomašević, Nataša, Koehbach, Johannes, Duerrauer, Leopold, Hadžić, Seid, Castro, Joel, Schober, Gudrun, Sideromenos, Spyridon, Clark, Richard J, Brierley, Stuart M, Craik, David J, Gruber, Christian W
Published in Journal of medicinal chemistry (08.07.2021)
Published in Journal of medicinal chemistry (08.07.2021)
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Augmented capacity for peripheral serotonin release in human obesity
Young, Richard L, Lumsden, Amanda L, Martin, Alyce M, Schober, Gudrun, Pezos, Nektaria, Thazhath, Sony S, Isaacs, Nicole J, Cvijanovic, Nada, Sun, Emily W L, Wu, Tongzhi, Rayner, Christopher K, Nguyen, Nam Q, Fontgalland, Dayan de, Rabbitt, Philippa, Hollington, Paul, Sposato, Luigi, Due, Steven L, Wattchow, David A, Liou, Alice P, Jackson, V Margaret, Keating, Damien J
Published in International Journal of Obesity (01.11.2018)
Published in International Journal of Obesity (01.11.2018)
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Su1578 – Chronic Intracolonic Administration of Linaclotide Inhibits Nociceptive Signaling in a Mouse Model of Chronic Visceral Hypersensitivity
Castro, Joel, Harrington, Andrea, Maddern, Jessica, Schober, Gudrun, Grundy, Luke A., Ge, Pei, Hannig, Gerhard, Brierley, Stuart
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2019)
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A Gut-Intrinsic Melanocortin Signaling Complex Augments L-Cell Secretion in Humans
Sun, Emily W., Iepsen, Eva W., Pezos, Nektaria, Lumsden, Amanda L., Martin, Alyce M., Schober, Gudrun, Isaacs, Nichole J., Rayner, Christopher K., Nguyen, Nam Q., de Fontgalland, Dayan, Rabbitt, Philippa, Hollington, Paul, Wattchow, David A., Hansen, Torben, Holm, Jens-Christian, Liou, Alice P., Jackson, V. Margaret, Torekov, Signe S., Young, Richard L., Keating, Damien J.
Published in Gastroenterology (New York, N.Y. 1943) (01.08.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.08.2021)
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Activation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivity
Castro, Joel, Harrington, Andrea M., Lieu, TinaMarie, Garcia-Caraballo, Sonia, Maddern, Jessica, Schober, Gudrun, O’Donnell, Tracey, Grundy, Luke, Lumsden, Amanda L., Miller, Paul, Ghetti, Andre, Steinhoff, Martin S., Poole, Daniel P., Dong, Xinzhong, Chang, Lin, Bunnett, Nigel W., Brierley, Stuart M.
Published in JCI insight (17.10.2019)
Published in JCI insight (17.10.2019)
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Journal Article
Intragastric administration of leucine or isoleucine lowers the blood glucose response to a mixed-nutrient drink by different mechanisms in healthy, lean volunteers12
Ullrich, Sina S, Fitzgerald, Penelope CE, Schober, Gudrun, Steinert, Robert E, Horowitz, Michael, Feinle-Bisset, Christine
Published in The American journal of clinical nutrition (01.11.2016)
Published in The American journal of clinical nutrition (01.11.2016)
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Journal Article
Pharmacological Inhibition of the Voltage-Gated Sodium Channel NaV1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome
Jiang, Yan, Castro, Joel, Blomster, Linda V, Agwa, Akello J, Maddern, Jessica, Schober, Gudrun, Herzig, Volker, Chow, Chun Yuen, Cardoso, Fernanda C, Demétrio De Souza França, Paula, Gonzales, Junior, Schroeder, Christina I, Esche, Steffen, Reiner, Thomas, Brierley, Stuart M, King, Glenn F
Published in ACS pharmacology & translational science (13.08.2021)
Published in ACS pharmacology & translational science (13.08.2021)
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Journal Article
Pharmacological Inhibition of the Voltage-Gated Sodium Channel Na V 1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome
Jiang, Yan, Castro, Joel, Blomster, Linda V, Agwa, Akello J, Maddern, Jessica, Schober, Gudrun, Herzig, Volker, Chow, Chun Yuen, Cardoso, Fernanda C, Demétrio De Souza França, Paula, Gonzales, Junior, Schroeder, Christina I, Esche, Steffen, Reiner, Thomas, Brierley, Stuart M, King, Glenn F
Published in ACS pharmacology & translational science (13.08.2021)
Published in ACS pharmacology & translational science (13.08.2021)
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