Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo
Pajak, Aleksandra, Laine, Isabelle, Clemente, Paula, El-Fissi, Najla, Schober, Florian A, Maffezzini, Camilla, Calvo-Garrido, Javier, Wibom, Rolf, Filograna, Roberta, Dhir, Ashish, Wedell, Anna, Freyer, Christoph, Wredenberg, Anna
Published in PLoS genetics (01.07.2019)
Published in PLoS genetics (01.07.2019)
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FBXL4 deficiency increases mitochondrial removal by autophagy
Alsina, David, Lytovchenko, Oleksandr, Schab, Aleksandra, Atanassov, Ilian, Schober, Florian A, Jiang, Min, Koolmeister, Camilla, Wedell, Anna, Taylor, Robert W, Wredenberg, Anna, Larsson, Nils‐Göran
Published in EMBO molecular medicine (07.07.2020)
Published in EMBO molecular medicine (07.07.2020)
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ANGEL2 phosphatase activity is required for non-canonical mitochondrial RNA processing
Clemente, Paula, Calvo-Garrido, Javier, Pearce, Sarah F, Schober, Florian A, Shigematsu, Megumi, Siira, Stefan J, Laine, Isabelle, Spåhr, Henrik, Steinmetzger, Christian, Petzold, Katja, Kirino, Yohei, Wibom, Rolf, Rackham, Oliver, Filipovska, Aleksandra, Rorbach, Joanna, Freyer, Christoph, Wredenberg, Anna
Published in Nature communications (30.09.2022)
Published in Nature communications (30.09.2022)
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SQSTM1/p62-Directed Metabolic Reprogramming Is Essential for Normal Neurodifferentiation
Calvo-Garrido, Javier, Maffezzini, Camilla, Schober, Florian A., Clemente, Paula, Uhlin, Elias, Kele, Malin, Stranneheim, Henrik, Lesko, Nicole, Bruhn, Helene, Svenningsson, Per, Falk, Anna, Wedell, Anna, Freyer, Christoph, Wredenberg, Anna
Published in Stem cell reports (09.04.2019)
Published in Stem cell reports (09.04.2019)
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Case Report: A Novel Mutation in the Mitochondrial MT-ND5 Gene Is Associated With Leber Hereditary Optic Neuropathy (LHON)
Engvall, Martin, Kawasaki, Aki, Carelli, Valerio, Wibom, Rolf, Bruhn, Helene, Lesko, Nicole, Schober, Florian A, Wredenberg, Anna, Wedell, Anna, Träisk, Frank
Published in Frontiers in neurology (25.03.2021)
Published in Frontiers in neurology (25.03.2021)
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TEFM regulates both transcription elongation and RNA processing in mitochondria
Jiang, Shan, Koolmeister, Camilla, Misic, Jelena, Siira, Stefan, Kühl, Inge, Silva Ramos, Eduardo, Miranda, Maria, Jiang, Min, Posse, Viktor, Lytovchenko, Oleksandr, Atanassov, Ilian, Schober, Florian A, Wibom, Rolf, Hultenby, Kjell, Milenkovic, Dusanka, Gustafsson, Claes M, Filipovska, Aleksandra, Larsson, Nils‐Göran
Published in EMBO reports (01.06.2019)
Published in EMBO reports (01.06.2019)
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Journal Article
C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis
Gopalakrishna, Shreekara, Pearce, Sarah F, Dinan, Adam M, Schober, Florian A, Cipullo, Miriam, Spåhr, Henrik, Khawaja, Anas, Maffezzini, Camilla, Freyer, Christoph, Wredenberg, Anna, Atanassov, Ilian, Firth, Andrew E, Rorbach, Joanna
Published in Nucleic acids research (26.09.2019)
Published in Nucleic acids research (26.09.2019)
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Journal Article
Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease
Schober, Florian A, Tang, Jia Xin, Sergeant, Kate, Moedas, Marco F, Zierz, Charlotte M, Moore, David, Smith, Conrad, Lewis, David, Guha, Nishan, Hopton, Sila, Falkous, Gavin, Lam, Amanda, Pyle, Angela, Poulton, Joanna, Gorman, Gráinne S, Taylor, Robert W, Freyer, Christoph, Wredenberg, Anna
Published in Human molecular genetics (22.06.2022)
Published in Human molecular genetics (22.06.2022)
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Journal Article
Severe congenital lactic acidosis and hypertrophic cardiomyopathy caused by an intronic variant in NDUFB7
Correia, Sandrina P., Moedas, Marco F., Naess, Karin, Bruhn, Helene, Maffezzini, Camilla, Calvo‐Garrido, Javier, Lesko, Nicole, Wibom, Rolf, Schober, Florian A., Jemt, Anders, Stranneheim, Henrik, Freyer, Christoph, Wedell, Anna, Wredenberg, Anna
Published in Human mutation (01.04.2021)
Published in Human mutation (01.04.2021)
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Journal Article
A multi-systemic mitochondrial disorder due to a dominant p.Y955H disease variant in DNA polymerase gamma
Siibak, Triinu, Clemente, Paula, Bratic, Ana, Bruhn, Helene, Kauppila, Timo E S, Macao, Bertil, Schober, Florian A, Lesko, Nicole, Wibom, Rolf, Naess, Karin, Nennesmo, Inger, Wedell, Anna, Peter, Bradley, Freyer, Christoph, Falkenberg, Maria, Wredenberg, Anna
Published in Human molecular genetics (01.07.2017)
Published in Human molecular genetics (01.07.2017)
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Journal Article
Novel Mutation m.10372A>G in MT-ND3 Causing Sensorimotor Axonal Polyneuropathy
Bruhn, Helene, Samuelsson, Kristin, Schober, Florian A, Engvall, Martin, Lesko, Nicole, Wibom, Rolf, Nennesmo, Inger, Calvo-Garrido, Javier, Press, Rayomand, Stranneheim, Henrik, Freyer, Christoph, Wedell, Anna, Wredenberg, Anna
Published in Neurology. Genetics (01.04.2021)
Published in Neurology. Genetics (01.04.2021)
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Robust dimethyl-based multiplex-DIA workflow doubles single-cell proteome depth via a reference channel
Thielert, Marvin, Corazon Ericka Mae Itang, Ammar, Constantin, Schober, Florian A, Bludau, Isabell, Skowronek, Patricia, Wahle, Maria, Wen-Feng, Zeng, Xie-Xuan, Zhou, Andreas-David Brunner, Richter, Sabrina, Theis, Fabian J, Steger, Martin, Mann, Matthias
Published in bioRxiv (03.12.2022)
Published in bioRxiv (03.12.2022)
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Paper
Stable Isotope Labeling of Amino Acids in Flies (SILAF) Reveals Differential Phosphorylation of Mitochondrial Proteins Upon Loss of OXPHOS Subunits
Rosenberger, Florian A., Atanassov, Ilian, Moore, David, Calvo-Garrido, Javier, Moedas, Marco F., Wedell, Anna, Freyer, Christoph, Wredenberg, Anna
Published in Molecular & cellular proteomics (01.01.2021)
Published in Molecular & cellular proteomics (01.01.2021)
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Journal Article
FBXL 4 deficiency increases mitochondrial removal by autophagy
Alsina, David, Lytovchenko, Oleksandr, Schab, Aleksandra, Atanassov, Ilian, Schober, Florian A, Jiang, Min, Koolmeister, Camilla, Wedell, Anna, Taylor, Robert W, Wredenberg, Anna, Larsson, Nils‐Göran
Published in EMBO molecular medicine (07.07.2020)
Published in EMBO molecular medicine (07.07.2020)
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Journal Article
The one-carbon pool controls mitochondrial energy metabolism via complex I and iron-sulfur clusters
Rosenberger, Florian A, Moore, David, Atanassov, Ilian, Moedas, Marco F, Clemente, Paula, Végvári, Ákos, Fissi, Najla El, Filograna, Roberta, Bucher, Anna-Lena, Hinze, Yvonne, The, Matthew, Hedman, Erik, Chernogubova, Ekaterina, Begzati, Arjana, Wibom, Rolf, Jain, Mohit, Nilsson, Roland, Käll, Lukas, Wedell, Anna, Freyer, Christoph, Wredenberg, Anna
Published in Science advances (19.02.2021)
Published in Science advances (19.02.2021)
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Journal Article
Versatile proteome labelling in fruit flies with SILAF
Schober, Florian A, Atanassov, Ilian, Moore, David, Wedell, Anna, Freyer, Christoph, Wredenberg, Anna
Published in bioRxiv (29.03.2019)
Published in bioRxiv (29.03.2019)
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Paper
Case Report: A Novel Mutation in the Mitochondrial MT-ND5 Gene Is Associated With Leber Hereditary Optic Neuropathy (LHON)
Engvall, Martin, Kawasaki, Aki, Carelli, Valerio, Wibom, Rolf, Bruhn, Helene, Lesko, Nicole, Schober, Florian A, Wredenberg, Anna, Wedell, Anna, Träisk, Frank
Published in Frontiers in neurology (01.01.2021)
Published in Frontiers in neurology (01.01.2021)
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