The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain
Schneppenheim, Janna, Dressel, Ralf, Hüttl, Susann, Lüllmann-Rauch, Renate, Engelke, Michael, Dittmann, Kai, Wienands, Jürgen, Eskelinen, Eeva-Liisa, Hermans-Borgmeyer, Irm, Fluhrer, Regina, Saftig, Paul, Schröder, Bernd
Published in The Journal of experimental medicine (14.01.2013)
Published in The Journal of experimental medicine (14.01.2013)
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Journal Article
Processing of CD74 by the Intramembrane Protease SPPL2a Is Critical for B Cell Receptor Signaling in Transitional B Cells
Hüttl, Susann, Kläsener, Kathrin, Schweizer, Michaela, Schneppenheim, Janna, Oberg, Hans-Heinrich, Kabelitz, Dieter, Reth, Michael, Saftig, Paul, Schröder, Bernd
Published in The Journal of immunology (1950) (15.08.2015)
Published in The Journal of immunology (1950) (15.08.2015)
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Journal Article
The Influence of MHC Class II on B Cell Defects Induced by Invariant Chain/CD74 N-Terminal Fragments
Schneppenheim, Janna, Loock, Ann-Christine, Hüttl, Susann, Schweizer, Michaela, Lüllmann-Rauch, Renate, Oberg, Hans-Heinrich, Arnold, Philipp, Lehmann, Christian H K, Dudziak, Diana, Kabelitz, Dieter, Lucius, Ralph, Lennon-Duménil, Ana-Maria, Saftig, Paul, Schröder, Bernd
Published in The Journal of immunology (1950) (01.07.2017)
Published in The Journal of immunology (1950) (01.07.2017)
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Journal Article
The Intramembrane Protease SPPL2A Is Critical for Tooth Enamel Formation
Bronckers, Antonius LJJ, Gueneli, Nur, Lüllmann‐Rauch, Renate, Schneppenheim, Janna, Moraru, Andreea P, Himmerkus, Nina, Bervoets, Theodore J, Fluhrer, Regina, Everts, Vincent, Saftig, Paul, Schröder, Bernd
Published in Journal of bone and mineral research (01.07.2013)
Published in Journal of bone and mineral research (01.07.2013)
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Journal Article
Aldosterone exerts anti-inflammatory effects on LPS stimulated microglia
Bast, Björn-Ole, Rickert, Uta, Schneppenheim, Janna, Cossais, François, Wilms, Henrik, Arnold, Philipp, Lucius, Ralph
Published in Heliyon (01.10.2018)
Published in Heliyon (01.10.2018)
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Journal Article
Meprin β cleaves TREM2 and controls its phagocytic activity on macrophages
Berner, Dennis Kristopher, Wessolowski, Luisa, Armbrust, Fred, Schneppenheim, Janna, Schlepckow, Kai, Koudelka, Tomas, Scharfenberg, Franka, Lucius, Ralph, Tholey, Andreas, Kleinberger, Gernot, Haass, Christian, Arnold, Philipp, Becker‐Pauly, Christoph
Published in The FASEB journal (01.05.2020)
Published in The FASEB journal (01.05.2020)
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Journal Article
Trefoil factor 3 shows anti-inflammatory effects on activated microglia
Arnold, Philipp, Rickert, Uta, Helmers, Ann-Kristin, Spreu, Jessica, Schneppenheim, Janna, Lucius, Ralph
Published in Cell and tissue research (01.07.2016)
Published in Cell and tissue research (01.07.2016)
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Journal Article
Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling
Arnold, Philipp, Boll, Inga, Rothaug, Michelle, Schumacher, Neele, Schmidt, Frederike, Wichert, Rielana, Schneppenheim, Janna, Lokau, Juliane, Pickhinke, Ute, Koudelka, Tomas, Tholey, Andreas, Rabe, Björn, Scheller, Jürgen, Lucius, Ralph, Garbers, Christoph, Rose-John, Stefan, Becker-Pauly, Christoph
Published in Scientific reports (09.03.2017)
Published in Scientific reports (09.03.2017)
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Journal Article
Meprin β and BMP-1 are differentially regulated by CaCl2
Schneppenheim, Janna, Scharfenberg, Franka, Lucius, Ralph, Becker-Pauly, Christoph, Arnold, Philipp
Published in Cell calcium (Edinburgh) (01.07.2017)
Published in Cell calcium (Edinburgh) (01.07.2017)
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Journal Article
Regulation of adult hematopoiesis by the a disintegrin and metalloproteinase 10 (ADAM10)
Weber, Silvio, Wetzel, Sebastian, Prox, Johannes, Lehmann, Tobias, Schneppenheim, Janna, Donners, Marjo, Saftig, Paul
Published in Biochemical and biophysical research communications (13.12.2013)
Published in Biochemical and biophysical research communications (13.12.2013)
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Journal Article
Meprin β and BMP-1 are differentially regulated by CaCl 2
Schneppenheim, Janna, Scharfenberg, Franka, Lucius, Ralph, Becker-Pauly, Christoph, Arnold, Philipp
Published in Cell calcium (Edinburgh) (01.07.2017)
Published in Cell calcium (Edinburgh) (01.07.2017)
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Journal Article
The Intramembrane Proteases Signal Peptide Peptidase-Like 2a and 2b Have Distinct Functions In Vivo
Schneppenheim, Janna, Hüttl, Susann, Mentrup, Torben, Lüllmann-Rauch, Renate, Rothaug, Michelle, Engelke, Michael, Dittmann, Kai, Dressel, Ralf, Araki, Masatake, Araki, Kimi, Wienands, Jürgen, Fluhrer, Regina, Saftig, Paul, Schröder, Bernd
Published in Molecular and cellular biology (01.04.2014)
Published in Molecular and cellular biology (01.04.2014)
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Journal Article
Functional characterization of the lysosomal membrane protein TMEM192 in mice
Nguyen, Thuy Linh, Schneppenheim, Janna, Rudnik, Sönke, Lüllmann-Rauch, Renate, Bernreuther, Christian, Hermans-Borgmeyer, Irm, Glatzel, Markus, Saftig, Paul, Schröder, Bernd
Published in Oncotarget (04.07.2017)
Published in Oncotarget (04.07.2017)
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Journal Article
Signal-peptide-peptidase-like 2a is required for CD74 intramembrane proteolysis in human B cells
Schneppenheim, Janna, Hüttl, Susann, Kruchen, Anne, Fluhrer, Regina, Müller, Ingo, Saftig, Paul, Schneppenheim, Reinhard, Martin, Christa L., Schröder, Bernd
Published in Biochemical and biophysical research communications (15.08.2014)
Published in Biochemical and biophysical research communications (15.08.2014)
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Journal Article