A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC
Mohammad, Helai P., Smitheman, Kimberly N., Kamat, Chandrashekhar D., Soong, David, Federowicz, Kelly E., Van Aller, Glenn S., Schneck, Jess L., Carson, Jeffrey D., Liu, Yan, Butticello, Michael, Bonnette, William G., Gorman, Shelby A., Degenhardt, Yan, Bai, Yuchen, McCabe, Michael T., Pappalardi, Melissa B., Kasparec, Jiri, Tian, Xinrong, McNulty, Kenneth C., Rouse, Meagan, McDevitt, Patrick, Ho, Thau, Crouthamel, Michelle, Hart, Timothy K., Concha, Nestor O., McHugh, Charles F., Miller, William H., Dhanak, Dashyant, Tummino, Peter J., Carpenter, Christopher L., Johnson, Neil W., Hann, Christine L., Kruger, Ryan G.
Published in Cancer cell (13.07.2015)
Published in Cancer cell (13.07.2015)
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Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36
Poulin, Myles B., Schneck, Jessica L., Matico, Rosalie E., McDevitt, Patrick J., Huddleston, Michael J., Hou, Wangfang, Johnson, Neil W., Thrall, Sara H., Meek, Thomas D., Schramm, Vern L.
Published in Proceedings of the National Academy of Sciences - PNAS (02.02.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (02.02.2016)
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Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells
Billiard, Julia, Dennison, Jennifer B, Briand, Jacques, Annan, Roland S, Chai, Deping, Colón, Mariela, Dodson, Christopher S, Gilbert, Seth A, Greshock, Joel, Jing, Junping, Lu, Hong, McSurdy-Freed, Jeanelle E, Orband-Miller, Lisa A, Mills, Gordon B, Quinn, Chad J, Schneck, Jessica L, Scott, Gilbert F, Shaw, Anthony N, Waitt, Gregory M, Wooster, Richard F, Duffy, Kevin J
Published in Cancer & metabolism (06.09.2013)
Published in Cancer & metabolism (06.09.2013)
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Design of amidobenzimidazole STING receptor agonists with systemic activity
Ramanjulu, Joshi M., Pesiridis, G. Scott, Yang, Jingsong, Concha, Nestor, Singhaus, Robert, Zhang, Shu-Yun, Tran, Jean-Luc, Moore, Patrick, Lehmann, Stephanie, Eberl, H. Christian, Muelbaier, Marcel, Schneck, Jessica L., Clemens, Jim, Adam, Michael, Mehlmann, John, Romano, Joseph, Morales, Angel, Kang, James, Leister, Lara, Graybill, Todd L., Charnley, Adam K., Ye, Guosen, Nevins, Neysa, Behnia, Kamelia, Wolf, Amaya I., Kasparcova, Viera, Nurse, Kelvin, Wang, Liping, Puhl, Ana C., Li, Yue, Klein, Michael, Hopson, Christopher B., Guss, Jeffrey, Bantscheff, Marcus, Bergamini, Giovanna, Reilly, Michael A., Lian, Yiqian, Duffy, Kevin J., Adams, Jerry, Foley, Kevin P., Gough, Peter J., Marquis, Robert W., Smothers, James, Hoos, Axel, Bertin, John
Published in Nature (London) (01.12.2018)
Published in Nature (London) (01.12.2018)
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A highly selective, cell-permeable furin inhibitor BOS-318 rescues key features of cystic fibrosis airway disease
Douglas, Lisa E.J., Reihill, James A., Ho, Melisa W.Y., Axten, Jeffrey M., Campobasso, Nino, Schneck, Jessica L., Rendina, Alan R., Wilcoxen, Keith M., Martin, S. Lorraine
Published in Cell chemical biology (16.06.2022)
Published in Cell chemical biology (16.06.2022)
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Targeting the Regulatory Site of ER Aminopeptidase 1 Leads to the Discovery of a Natural Product Modulator of Antigen Presentation
Liddle, John, Hutchinson, Jonathan P, Kitchen, Semra, Rowland, Paul, Neu, Margarete, Cecconie, Ted, Holmes, Duncan S, Jones, Emma, Korczynska, Justyna, Koumantou, Despoina, Lea, Jonathan D, Nickels, Leng, Pemberton, Michelle, Phillipou, Alex, Schneck, Jessica L, Sheehan, Hester, Tinworth, Christopher P, Uings, Iain, Wojno-Picon, Justyna, Young, Robert J, Stratikos, Efstratios
Published in Journal of medicinal chemistry (26.03.2020)
Published in Journal of medicinal chemistry (26.03.2020)
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Exploration of the P1 residue in 3CL protease inhibitors leading to the discovery of a 2-tetrahydrofuran P1 replacement
Barton, Linda S., Callahan, James F., Cantizani, Juan, Concha, Nestor O., Cotillo Torrejon, Ignacio, Goodwin, Nicole C., Joshi-Pangu, Amruta, Kiesow, Terry J., McAtee, Jeff J., Mellinger, Mark, Nixon, Christopher J., Padrón-Barthe, Laura, Patterson, Jaclyn R., Pearson, Neil D., Pouliot, Jeffrey J., Rendina, Alan R., Buitrago Santanilla, Alexander, Schneck, Jessica L., Sanz, Olalla, Thalji, Reema K., Ward, Paris, Williams, Shawn P., King, Bryan W.
Published in Bioorganic & medicinal chemistry (15.02.2024)
Published in Bioorganic & medicinal chemistry (15.02.2024)
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Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells
Picco, Gabriele, Rao, Yanhua, Al Saedi, Angham, Lee, Yang, Vieira, Sara F, Bhosle, Shriram, May, Kieron, Herranz-Ors, Carmen, Walker, Samantha J, Shenje, Raynold, Dincer, Cansu, Gibson, Freddy, Banerjee, Ruby, Hewitson, Zoe, Werner, Thilo, Cottom, Joshua E, Peng, Yang, Deng, Nanhua, Zhang, Youyou, Nartey, Eldridge N, Nickels, Leng, Landis, Philip, Conticelli, Daniela, McCarten, Katrina, Bush, Jacob, Sharma, Mamta, Lightfoot, Howard, House, David, Milford, Emma, Grant, Emma K, Glogowski, Michal P, Wagner, Craig D, Bantscheff, Marcus, Rutkowska-Klute, Anna, Zappacosta, Francesca, Pettinger, Jonathan, Barthorpe, Syd, Eberl, H Christian, Jones, Brian T, Schneck, Jessica L, Murphy, Dennis J, Voest, Emile E, Taygerly, Joshua P, DeMartino, Michael P, Coelho, Matthew A, Houseley, Jonathan, Sharma, Geeta, Schwartz, Benjamin, Garnett, Mathew J
Published in Cancer discovery (02.08.2024)
Published in Cancer discovery (02.08.2024)
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Nucleosome Binding Alters the Substrate Bonding Environment of Histone H3 Lysine 36 Methyltransferase NSD2
Poulin, Myles B, Schneck, Jessica L, Matico, Rosalie E, Hou, Wangfang, McDevitt, Patrick J, Holbert, Marc, Schramm, Vern L
Published in Journal of the American Chemical Society (01.06.2016)
Published in Journal of the American Chemical Society (01.06.2016)
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A Scalable Platform for Producing Recombinant Nucleosomes with Codified Histone Methyltransferase Substrate Preferences
McDevitt, Patrick J., Schneck, Jessica L., Diaz, Elsie, Hou, Wangfang, Huddleston, Michael J., Matico, Rosalie E., McCormick, Patricia M., Kirkpatrick, Robert B.
Published in Protein expression and purification (01.12.2019)
Published in Protein expression and purification (01.12.2019)
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Author Correction: Design of amidobenzimidazole STING receptor agonists with systemic activity
Ramanjulu, Joshi M., Pesiridis, G. Scott, Yang, Jingsong, Concha, Nestor, Singhaus, Robert, Zhang, Shu-Yun, Tran, Jean-Luc, Moore, Patrick, Lehmann, Stephanie, Eberl, H. Christian, Muelbaier, Marcel, Schneck, Jessica L., Clemens, Jim, Adam, Michael, Mehlmann, John, Romano, Joseph, Morales, Angel, Kang, James, Leister, Lara, Graybill, Todd L., Charnley, Adam K., Ye, Guosen, Nevins, Neysa, Behnia, Kamelia, Wolf, Amaya I., Kasparcova, Viera, Nurse, Kelvin, Wang, Liping, Puhl, Ana C., Li, Yue, Klein, Michael, Hopson, Christopher B., Guss, Jeffrey, Bantscheff, Marcus, Bergamini, Giovanna, Reilly, Michael A., Lian, Yiqian, Duffy, Kevin J., Adams, Jerry, Foley, Kevin P., Gough, Peter J., Marquis, Robert W., Smothers, James, Hoos, Axel, Bertin, John
Published in Nature (London) (01.06.2019)
Published in Nature (London) (01.06.2019)
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The Amino-Acid Substituents of Dipeptide Substrates of Cathepsin C Can Determine the Rate-Limiting Steps of Catalysis
Rubach, Jon K, Cui, Guanglei, Schneck, Jessica L, Taylor, Amy N, Zhao, Baoguang, Smallwood, Angela, Nevins, Neysa, Wisnoski, David, Thrall, Sara H, Meek, Thomas D
Published in Biochemistry (Easton) (25.09.2012)
Published in Biochemistry (Easton) (25.09.2012)
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Chemical Mechanism of a Cysteine Protease, Cathepsin C, As Revealed by Integration of both Steady-State and Pre-Steady-State Solvent Kinetic Isotope Effects
Schneck, Jessica L, Villa, James P, McDevitt, Patrick, McQueney, Michael S, Thrall, Sara H, Meek, Thomas D
Published in Biochemistry (Easton) (19.08.2008)
Published in Biochemistry (Easton) (19.08.2008)
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