A Heterozygous Mutation of the Insulin-Like Growth Factor-I Receptor Causes Retention of the Nascent Protein in the Endoplasmic Reticulum and Results in Intrauterine and Postnatal Growth Retardation
Wallborn, Tillmann, Wüller, Stefan, Klammt, Jürgen, Kruis, Tassilo, Kratzsch, Jürgen, Schmidt, Gabriele, Schlicke, Marina, Müller, Eva, Schmitz van de Leur, Hildegard, Kiess, Wieland, Pfäffle, Roland
Published in The journal of clinical endocrinology and metabolism (01.05.2010)
Published in The journal of clinical endocrinology and metabolism (01.05.2010)
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Journal Article
Src family kinases interfere with dimerization of STAT5A through a phosphotyrosine-SH2 domain interaction
Fahrenkamp, Dirk, de Leur, Hildegard Schmitz-Van, Küster, Andrea, Chatain, Nicolas, Müller-Newen, Gerhard
Published in Cell communication and signaling (15.02.2015)
Published in Cell communication and signaling (15.02.2015)
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Journal Article
Novel Role of Janus Kinase 1 in the Regulation of Oncostatin M Receptor Surface Expression
Radtke, Simone, Hermanns, Heike M., Haan, Claude, Schmitz-Van de Leur, Hildegard, Heinrich, Peter C., Behrmann, Iris, Gascan, Hugues
Published in The Journal of biological chemistry (29.03.2002)
Published in The Journal of biological chemistry (29.03.2002)
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Journal Article
Three Dileucine-like Motifs within the Interbox1/2 Region of the Human Oncostatin M Receptor Prevent Efficient Surface Expression in the Absence of an Associated Janus Kinase
Radtke, Simone, Jörissen, Angela, de Leur, Hildegard Schmitz-Van, Heinrich, Peter C., Behrmann, Iris
Published in The Journal of biological chemistry (17.02.2006)
Published in The Journal of biological chemistry (17.02.2006)
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Journal Article
Cross-regulation of cytokine signalling: pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradation
Radtke, Simone, Wüller, Stefan, Yang, Xiang-ping, Lippok, Barbara E, Mütze, Barbara, Mais, Christine, de Leur, Hildegard Schmitz-Van, Bode, Johannes G, Gaestel, Matthias, Heinrich, Peter C, Behrmann, Iris, Schaper, Fred, Hermanns, Heike M
Published in Journal of cell science (15.03.2010)
Published in Journal of cell science (15.03.2010)
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Journal Article
Intramolecular hydrophobic interactions are critical mediators of STAT5 dimerization
Fahrenkamp, Dirk, Li, Jinyu, Ernst, Sabrina, Schmitz-Van de Leur, Hildegard, Chatain, Nicolas, Küster, Andrea, Koschmieder, Steffen, Lüscher, Bernhard, Rossetti, Giulia, Müller-Newen, Gerhard
Published in Scientific reports (18.10.2016)
Published in Scientific reports (18.10.2016)
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Journal Article
Dual Role of the Jak1 FERM and Kinase Domains in Cytokine Receptor Binding and in Stimulation-Dependent Jak Activation
Haan, Serge, Margue, Christiane, Engrand, Arnaud, Rolvering, Catherine, Schmitz-Van de Leur, Hildegard, Heinrich, Peter C, Behrmann, Iris, Haan, Claude
Published in The Journal of immunology (1950) (15.01.2008)
Published in The Journal of immunology (1950) (15.01.2008)
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Journal Article
A Single STAT Recruitment Module in a Chimeric Cytokine Receptor Complex Is Sufficient for STAT Activation
Behrmann, I, Janzen, C, Gerhartz, C, Schmitz-Van de Leur, H, Hermanns, H, Heesel, B, Graeve, L, Horn, F, Tavernier, J, Heinrich, P C
Published in The Journal of biological chemistry (21.02.1997)
Published in The Journal of biological chemistry (21.02.1997)
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Journal Article
Mapping of a Region within the N Terminus of Jak1 Involved in Cytokine Receptor Interaction
Haan, Claude, Is'harc, Hayaatun, Hermanns, Heike M., Schmitz-Van de Leur, Hildegard, Kerr, Ian M., Heinrich, Peter C., Grötzinger, Joachim, Behrmann, Iris
Published in The Journal of biological chemistry (05.10.2001)
Published in The Journal of biological chemistry (05.10.2001)
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Journal Article
Janus Kinase (Jak) Subcellular Localization Revisited
Iris Behrmann, Tanja Smyczek, Peter C. Heinrich, Hildegard Schmitz-Van de Leur, Waraporn Komyod, Bernd Giese, Gerhard Müller-Newen, Serge Haan, Claude Haan
Published in The Journal of biological chemistry (20.08.2004)
Published in The Journal of biological chemistry (20.08.2004)
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Journal Article
Nuclear translocation of STAT3 and NF-κB are independent of each other but NF-κB supports expression and activation of STAT3
Martincuks, Antons, Andryka, Katarzyna, Küster, Andrea, Schmitz-Van de Leur, Hildegard, Komorowski, Michal, Müller-Newen, Gerhard
Published in Cellular signalling (01.04.2017)
Published in Cellular signalling (01.04.2017)
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Journal Article
Combining Two Mutations of Human Interleukin-6 That Affect gp130 Activation Results in a Potent Interleukin-6 Receptor Antagonist on Human Myeloma Cells (∗)
Ehlers, Marc, de Hon, Floris D., Bos, Hanny Klaasse, Horsten, Ursula, Kurapkat, Günther, van De Leur, Hildegard Schmitz, Grötzinger, Joachim, Wollmer, Axel, Brakenhoff, Just P.J., Rose-John, Stefan
Published in The Journal of biological chemistry (07.04.1995)
Published in The Journal of biological chemistry (07.04.1995)
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Journal Article
Anti-interleukin-6 therapy through application of a monogenic protein inhibitor via gene delivery
Görtz, Dieter, Braun, Gerald S, Maruta, Yuichi, Djudjaj, Sonja, van Roeyen, Claudia R, Martin, Ina V, Küster, Andrea, Schmitz-Van de Leur, Hildegard, Scheller, Jürgen, Ostendorf, Tammo, Floege, Jürgen, Müller-Newen, Gerhard
Published in Scientific reports (01.10.2015)
Published in Scientific reports (01.10.2015)
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Journal Article
A Heterozygous Mutation of the Insulin-Like Growth Factor-I Receptor Causes Retention of the Nascent Protein in the Endoplasmic Reticulum and Results in Intrauterine and Postnatal Growth Retardation
Wallborn, Tillmann, Wüller, Stefan, Klammt, Jürgen, Kruis, Tassilo, Kratzsch, Jürgen, Schmidt, Gabriele, Schlicke, Marina, Müller, Eva, Schmitz van de Leur, Hildegard, Kiess, Wieland, Pfäffle, Roland
Published in Endocrine reviews (01.04.2010)
Published in Endocrine reviews (01.04.2010)
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Journal Article
A Heterozygous Mutation of the Insulin-Like Growth Factor-I Receptor Causes Retention of the Nascent Protein in the Endoplasmic Reticulum and Results in Intrauterine and Postnatal Growth Retardation
Wallborn, Tillmann, Wüller, Stefan, Klammt, Jürgen, Kruis, Tassilo, Kratzsch, Jürgen, Schmidt, Gabriele, Schlicke, Marina, Müller, Eva, Schmitz van de Leur, Hildegard, Kiess, Wieland, Pfäffle, Roland
Published in Molecular endocrinology (Baltimore, Md.) (01.04.2010)
Published in Molecular endocrinology (Baltimore, Md.) (01.04.2010)
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Journal Article
Contributions of Leukemia Inhibitory Factor Receptor and Oncostatin M Receptor to Signal Transduction in Heterodimeric Complexes with Glycoprotein 130
Hermanns, Heike M, Radtke, Simone, Haan, Claude, Schmitz-Van de Leur, Hildegard, Tavernier, Jan, Heinrich, Peter C, Behrmann, Iris
Published in The Journal of immunology (1950) (15.12.1999)
Published in The Journal of immunology (1950) (15.12.1999)
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Journal Article
Janus kinase (Jak) subcellular localization revisited: the exclusive membrane localization of endogenous Janus kinase 1 by cytokine receptor interaction uncovers the Jak.receptor complex to be equivalent to a receptor tyrosine kinase
Behrmann, Iris, Smyczek, Tanja, Heinrich, Peter C, Schmitz-Van de Leur, Hildegard, Komyod, Waraporn, Giese, Bernd, Müller-Newen, Gerhard, Haan, Serge, Haan, Claude
Published in The Journal of biological chemistry (20.08.2004)
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Published in The Journal of biological chemistry (20.08.2004)
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