Network and Systems Medicine: Position Paper of the European Collaboration on Science and Technology Action on Open Multiscale Systems Medicine
Comte, Blandine, Baumbach, Jan, Benis, Arriel, Basílio, José, Debeljak, Nataša, Flobak, Åsmund, Franken, Christian, Harel, Nissim, He, Feng, Kuiper, Martin, Méndez Pérez, Juan Albino, Pujos-Guillot, Estelle, Režen, Tadeja, Rozman, Damjana, Schmid, Johannes A, Scerri, Jeanesse, Tieri, Paolo, Van Steen, Kristel, Vasudevan, Sona, Watterson, Steven, Schmidt, Harald H H W
Published in Network and systems medicine (2020)
Published in Network and systems medicine (2020)
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The 1027th target candidate in stroke: Will NADPH oxidase hold up?
Radermacher, Kim A, Wingler, Kirstin, Kleikers, Pamela, Altenhöfer, Sebastian, Jr Hermans, Johannes, Kleinschnitz, Christoph, Hhw Schmidt, Harald
Published in Experimental & translational stroke medicine (24.05.2012)
Published in Experimental & translational stroke medicine (24.05.2012)
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THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes
Alexander, Stephen PH, Fabbro, Doriano, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A, Beuve, Annie, Boison, Detlev, Brouckaert, Peter, Burnett, John C, Burns, Kathryn, Dessauer, Carmen, Friebe, Andreas, Garthwaite, John, Gertsch, Jürg, Helsby, Nuala, Izzo, Angelo A, Koesling, Doris, Kuhn, Michaela, Ostrom, Rennolds, Papapetropoulos, Andreas, Potter, Lincoln R, Pyne, Nigel J, Pyne, Susan, Russwurm, Michael, Schmidt, Harald HHW, Seifert, Roland, Stasch, Johannes‐Peter, Szabo, Csaba, van der Stelt, Mario, van der Vliet, Albert, Watts, Val
Published in British journal of pharmacology (01.12.2019)
Published in British journal of pharmacology (01.12.2019)
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Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification
Furmanik, Malgorzata, Chatrou, Martijn, van Gorp, Rick, Akbulut, Asim, Willems, Brecht, Schmidt, Harald, van Eys, Guillaume, Bochaton-Piallat, Marie-Luce, Proudfoot, Diane, Biessen, Erik, Hedin, Ulf, Perisic, Ljubica, Mees, Barend, Shanahan, Catherine, Reutelingsperger, Chris, Schurgers, Leon
Published in Circulation research (11.09.2020)
Published in Circulation research (11.09.2020)
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Combined NOX1/4 inhibition with GKT137831 in mice provides dose-dependent reno- and atheroprotection even in established micro- and macrovascular disease
Gray, Stephen P., Jha, Jay C., Kennedy, Kit, van Bommel, Erik, Chew, Phyllis, Szyndralewiez, Cedric, Touyz, Rhian M., Schmidt, Harald H. H. W., Cooper, Mark E., Jandeleit-Dahm, Karin A. M.
Published in Diabetologia (01.05.2017)
Published in Diabetologia (01.05.2017)
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Calcium-dependent blood-brain barrier breakdown by NOX5 limits postreperfusion benefit in stroke
Casas, Ana I, Kleikers, Pamela Wm, Geuss, Eva, Langhauser, Friederike, Adler, Thure, Busch, Dirk H, Gailus-Durner, Valerie, de Angelis, Martin Hrabê, Egea, Javier, Lopez, Manuela G, Kleinschnitz, Christoph, Schmidt, Harald Hhw
Published in The Journal of clinical investigation (01.04.2019)
Published in The Journal of clinical investigation (01.04.2019)
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NOX toolbox: validating the role of NADPH oxidases in physiology and disease
Altenhöfer, Sebastian, Kleikers, Pamela W. M, Radermacher, Kim A, Scheurer, Peter, Rob Hermans, J. J, Schiffers, Paul, Ho, Heidi, Wingler, Kirstin, Schmidt, Harald H. H. W
Published in Cellular and molecular life sciences : CMLS (01.07.2012)
Published in Cellular and molecular life sciences : CMLS (01.07.2012)
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NADPH oxidase, NOX1, mediates vascular injury in ischemic retinopathy
Wilkinson-Berka, Jennifer L, Deliyanti, Devy, Rana, Indrajeetsinh, Miller, Antonia G, Agrotis, Alex, Armani, Roksana, Szyndralewiez, Cédric, Wingler, Kirstin, Touyz, Rhian M, Cooper, Mark E, Jandeleit-Dahm, Karin A, Schmidt, Harald H H W
Published in Antioxidants & redox signaling (10.06.2014)
Published in Antioxidants & redox signaling (10.06.2014)
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NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential
Evgenov, Oleg V, Pacher, Pál, Schmidt, Peter M, Haskó, György, Schmidt, Harald H. H. W, Stasch, Johannes-Peter
Published in Nature reviews. Drug discovery (01.09.2006)
Published in Nature reviews. Drug discovery (01.09.2006)
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Imaging Reactive Oxygen Species-Induced Modifications in Living Systems
Maulucci, Giuseppe, Bačić, Goran, Bridal, Lori, Schmidt, Harald Hhw, Tavitian, Bertrand, Viel, Thomas, Utsumi, Hideo, Yalçın, A Süha, De Spirito, Marco
Published in Antioxidants & redox signaling (01.06.2016)
Published in Antioxidants & redox signaling (01.06.2016)
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Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production
Dikalov, Sergey I., Dikalova, Anna E., Bikineyeva, Alfiya T., Schmidt, Harald H.H.W., Harrison, David G., Griendling, Kathy K.
Published in Free radical biology & medicine (01.11.2008)
Published in Free radical biology & medicine (01.11.2008)
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Independent of Renox, NOX5 Promotes Renal Inflammation and Fibrosis in Diabetes by Activating ROS-Sensitive Pathways
Jha, Jay C, Dai, Aozhi, Garzarella, Jessica, Charlton, Amelia, Urner, Sofia, Østergaard, Jakob A, Okabe, Jun, Holterman, Chet E, Skene, Alison, Power, David A, Ekinci, Elif I, Coughlan, Melinda T, Schmidt, Harald H H W, Cooper, Mark E, Touyz, Rhian M, Kennedy, Chris R, Jandeleit-Dahm, Karin
Published in Diabetes (New York, N.Y.) (01.06.2022)
Published in Diabetes (New York, N.Y.) (01.06.2022)
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Neuroprotection after stroke by targeting NOX4 as a source of oxidative stress
Radermacher, Kim A, Wingler, Kirstin, Langhauser, Friederike, Altenhöfer, Sebastian, Kleikers, Pamela, Hermans, J J Rob, Hrabě de Angelis, Martin, Kleinschnitz, Christoph, Schmidt, Harald H H W
Published in Antioxidants & redox signaling (20.04.2013)
Published in Antioxidants & redox signaling (20.04.2013)
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Re-Addressing Dementia by Network Medicine and Mechanism-Based Molecular Endotypes
Pacheco Pachado, Mayra, Casas, Ana I., Elbatreek, Mahmoud H., Nogales, Cristian, Guney, Emre, Espay, Alberto J., Schmidt, Harald H.H.W.
Published in Journal of Alzheimer's disease (01.01.2023)
Published in Journal of Alzheimer's disease (01.01.2023)
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Activation of TRPC6 channels is essential for lung ischaemia–reperfusion induced oedema in mice
Weissmann, Norbert, Sydykov, Akylbek, Kalwa, Hermann, Storch, Ursula, Fuchs, Beate, Mederos y Schnitzler, Michael, Brandes, Ralf P., Grimminger, Friedrich, Meissner, Marcel, Freichel, Marc, Offermanns, Stefan, Veit, Florian, Pak, Oleg, Krause, Karl-Heinz, Schermuly, Ralph T., Brewer, Alison C, Schmidt, Harald H.H.W., Seeger, Werner, Shah, Ajay M., Gudermann, Thomas, Ghofrani, Hossein A., Dietrich, Alexander
Published in Nature communications (31.01.2012)
Published in Nature communications (31.01.2012)
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NOX4 in Mitochondria: Yeast Two-Hybrid-Based Interaction with Complex I Without Relevance for Basal Reactive Oxygen Species?
Hirschhäuser, Christine, Bornbaum, Julia, Reis, Anna, Böhme, Sabrina, Kaludercic, Nina, Menabò, Roberta, Di Lisa, Fabio, Boengler, Kerstin, Shah, Ajay M, Schulz, Rainer, Schmidt, Harald H H W
Published in Antioxidants & redox signaling (10.11.2015)
Published in Antioxidants & redox signaling (10.11.2015)
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THE CONCISE GUIDE TO PHARMACOLOGY 2021/22
Alexander, Stephen P H, Fabbro, Doriano, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Beuve, Annie, Brouckaert, Peter, Bryant, Clare, Burnett, John C, Farndale, Richard W, Friebe, Andreas, Garthwaite, John, Hobbs, Adrian J, Jarvis, Gavin E, Kuhn, Michaela, MacEwan, David, Monie, Tom P, Potter, Lincoln R, Schmidt, Harald HHW, Waldman, Scott A
Published in British journal of pharmacology (01.10.2021)
Published in British journal of pharmacology (01.10.2021)
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Joining European Scientific Forces to Face Pandemics
Vasconcelos, M. Helena, Alcaro, Stefano, Arechavala-Gomeza, Virginia, Baumbach, Jan, Borges, Fernanda, Brevini, Tiziana A.L., Rivas, Javier De Las, Devaux, Yvan, Hozak, Pavel, Keinänen-Toivola, Minna M., Lattanzi, Giovanna, Mohr, Thomas, Murovska, Modra, Prusty, Bhupesh K., Quinlan, Roy A., Pérez-Sala, Dolores, Scheibenbogen, Carmen, Schmidt, Harald H.H.W., Silveira, Isabel, Tieri, Paolo, Tolios, Alexander, Riganti, Chiara
Published in Trends in Microbiology (01.02.2021)
Published in Trends in Microbiology (01.02.2021)
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Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice
Dikalova, Anna, Clempus, Roza, Lassègue, Bernard, Cheng, Guangjie, McCoy, James, Dikalov, Sergey, San Martin, Alejandra, Lyle, Alicia, Weber, David S, Weiss, Daiana, Taylor, W Robert, Schmidt, Harald H H W, Owens, Gary K, Lambeth, J David, Griendling, Kathy K
Published in Circulation (New York, N.Y.) (25.10.2005)
Published in Circulation (New York, N.Y.) (25.10.2005)
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A combined pre-clinical meta-analysis and randomized confirmatory trial approach to improve data validity for therapeutic target validation
Kleikers, Pamela WM, Hooijmans, Carlijn, Göb, Eva, Langhauser, Friederike, Rewell, Sarah SJ, Radermacher, Kim, Ritskes-Hoitinga, Merel, Howells, David W., Kleinschnitz, Christoph, HHW Schmidt, Harald
Published in Scientific reports (27.08.2015)
Published in Scientific reports (27.08.2015)
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