Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer
Lesina, Marina, Kurkowski, Magdalena U., Ludes, Katharina, Rose-John, Stefan, Treiber, Matthias, Klöppel, Günter, Yoshimura, Akihiko, Reindl, Wolfgang, Sipos, Bence, Akira, Shizuo, Schmid, Roland M., Algül, Hana
Published in Cancer cell (12.04.2011)
Published in Cancer cell (12.04.2011)
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Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes
Mueller, Sebastian, Engleitner, Thomas, Maresch, Roman, Zukowska, Magdalena, Lange, Sebastian, Kaltenbacher, Thorsten, Konukiewitz, Björn, Öllinger, Rupert, Zwiebel, Maximilian, Strong, Alex, Yen, Hsi-Yu, Banerjee, Ruby, Louzada, Sandra, Fu, Beiyuan, Seidler, Barbara, Götzfried, Juliana, Schuck, Kathleen, Hassan, Zonera, Arbeiter, Andreas, Schönhuber, Nina, Klein, Sabine, Veltkamp, Christian, Friedrich, Mathias, Rad, Lena, Barenboim, Maxim, Ziegenhain, Christoph, Hess, Julia, Dovey, Oliver M, Eser, Stefan, Parekh, Swati, Constantino-Casas, Fernando, de la Rosa, Jorge, Sierra, Marta I, Fraga, Mario, Mayerle, Julia, Klöppel, Günter, Cadiñanos, Juan, Liu, Pentao, Vassiliou, George, Weichert, Wilko, Steiger, Katja, Enard, Wolfgang, Schmid, Roland M, Yang, Fengtang, Unger, Kristian, Schneider, Günter, Varela, Ignacio, Bradley, Allan, Saur, Dieter, Rad, Roland
Published in Nature (London) (01.02.2018)
Published in Nature (London) (01.02.2018)
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Invasive pulmonary aspergillosis in critically ill patients with severe COVID-19 pneumonia: Results from the prospective AspCOVID-19 study
Lahmer, Tobias, Kriescher, Silja, Herner, Alexander, Rothe, Kathrin, Spinner, Christoph D, Schneider, Jochen, Mayer, Ulrich, Neuenhahn, Michael, Hoffmann, Dieter, Geisler, Fabian, Heim, Markus, Schneider, Gerhard, Schmid, Roland M, Huber, Wolfgang, Rasch, Sebastian
Published in PloS one (17.03.2021)
Published in PloS one (17.03.2021)
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Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer
Eser, Stefan, Reiff, Nina, Messer, Marlena, Seidler, Barbara, Gottschalk, Kathleen, Dobler, Melanie, Hieber, Maren, Arbeiter, Andreas, Klein, Sabine, Kong, Bo, Michalski, Christoph W., Schlitter, Anna Melissa, Esposito, Irene, Kind, Alexander J., Rad, Lena, Schnieke, Angelika E., Baccarini, Manuela, Alessi, Dario R., Rad, Roland, Schmid, Roland M., Schneider, Günter, Saur, Dieter
Published in Cancer cell (18.03.2013)
Published in Cancer cell (18.03.2013)
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Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
Mazur, Pawel K, Herner, Alexander, Mello, Stephano S, Wirth, Matthias, Hausmann, Simone, Sánchez-Rivera, Francisco J, Lofgren, Shane M, Kuschma, Timo, Hahn, Stephan A, Vangala, Deepak, Trajkovic-Arsic, Marija, Gupta, Aayush, Heid, Irina, Noël, Peter B, Braren, Rickmer, Erkan, Mert, Kleeff, Jörg, Sipos, Bence, Sayles, Leanne C, Heikenwalder, Mathias, Heßmann, Elisabeth, Ellenrieder, Volker, Esposito, Irene, Jacks, Tyler, Bradner, James E, Khatri, Purvesh, Sweet-Cordero, E Alejandro, Attardi, Laura D, Schmid, Roland M, Schneider, Guenter, Sage, Julien, Siveke, Jens T
Published in Nature medicine (01.10.2015)
Published in Nature medicine (01.10.2015)
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Automated polyp detection in the colorectum: a prospective study (with videos)
Klare, Peter, Sander, Christoph, Prinzen, Martin, Haller, Bernhard, Nowack, Sebastian, Abdelhafez, Mohamed, Poszler, Alexander, Brown, Hayley, Wilhelm, Dirk, Schmid, Roland M., von Delius, Stefan, Wittenberg, Thomas
Published in Gastrointestinal endoscopy (01.03.2019)
Published in Gastrointestinal endoscopy (01.03.2019)
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RelA and RelB Transcription Factors in Distinct Thymocyte Populations Control Lymphotoxin-Dependent Interleukin-17 Production in γδ T Cells
Powolny-Budnicka, Iwona, Riemann, Marc, Tänzer, Simone, Schmid, Roland M., Hehlgans, Thomas, Weih, Falk
Published in Immunity (Cambridge, Mass.) (25.03.2011)
Published in Immunity (Cambridge, Mass.) (25.03.2011)
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Accurate prediction of histological grading of intraductal papillary mucinous neoplasia using deep learning
Schulz, Dominik, Heilmaier, Markus, Phillip, Veit, Treiber, Matthias, Mayr, Ulrich, Lahmer, Tobias, Mueller, Julius, Demir, Ihsan Ekin, Friess, Helmut, Reichert, Maximilian, Schmid, Roland M, Abdelhafez, Mohamed
Published in Endoscopy (01.05.2023)
Published in Endoscopy (01.05.2023)
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EGF Receptor Is Required for KRAS-Induced Pancreatic Tumorigenesis
Ardito, Christine M., Grüner, Barbara M., Takeuchi, Kenneth K., Lubeseder-Martellato, Clara, Teichmann, Nicole, Mazur, Pawel K., DelGiorno, Kathleen E., Carpenter, Eileen S., Halbrook, Christopher J., Hall, Jason C., Pal, Debjani, Briel, Thomas, Herner, Alexander, Trajkovic-Arsic, Marija, Sipos, Bence, Liou, Geou-Yarh, Storz, Peter, Murray, Nicole R., Threadgill, David W., Sibilia, Maria, Washington, M. Kay, Wilson, Carole L., Schmid, Roland M., Raines, Elaine W., Crawford, Howard C., Siveke, Jens T.
Published in Cancer cell (11.09.2012)
Published in Cancer cell (11.09.2012)
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A deep learning model enables accurate prediction and quantification of pulmonary edema from chest X-rays
Schulz, Dominik, Rasch, Sebastian, Heilmaier, Markus, Abbassi, Rami, Poszler, Alexander, Ulrich, Jörg, Steinhardt, Manuel, Kaissis, Georgios A, Schmid, Roland M, Braren, Rickmer, Lahmer, Tobias
Published in Critical care (London, England) (26.05.2023)
Published in Critical care (London, England) (26.05.2023)
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Inhibition of Endothelial Notch Signaling Impairs Fatty Acid Transport and Leads to Metabolic and Vascular Remodeling of the Adult Heart
Jabs, Markus, Rose, Adam J, Lehmann, Lorenz H, Taylor, Jacqueline, Moll, Iris, Sijmonsma, Tjeerd P, Herberich, Stefanie E, Sauer, Sven W, Poschet, Gernot, Federico, Giuseppina, Mogler, Carolin, Weis, Eva-Maria, Augustin, Hellmut G, Yan, Minhong, Gretz, Norbert, Schmid, Roland M, Adams, Ralf H, Gröne, Hermann-Joseph, Hell, Rüdiger, Okun, Jürgen G, Backs, Johannes, Nawroth, Peter P, Herzig, Stephan, Fischer, Andreas
Published in Circulation (New York, N.Y.) (12.06.2018)
Published in Circulation (New York, N.Y.) (12.06.2018)
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Mesenchymal Plasticity Regulated by Prrx1 Drives Aggressive Pancreatic Cancer Biology
Feldmann, Karin, Maurer, Carlo, Peschke, Katja, Teller, Steffen, Schuck, Kathleen, Steiger, Katja, Engleitner, Thomas, Öllinger, Rupert, Nomura, Alice, Wirges, Nils, Papargyriou, Aristeidis, Jahan Sarker, Rim Sabrina, Ranjan, Raphela Aranie, Dantes, Zahra, Weichert, Wilko, Rustgi, Anil K., Schmid, Roland M., Rad, Roland, Schneider, Günter, Saur, Dieter, Reichert, Maximilian
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2021)
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CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice
Weber, Julia, Öllinger, Rupert, Friedrich, Mathias, Ehmer, Ursula, Barenboim, Maxim, Steiger, Katja, Heid, Irina, Mueller, Sebastian, Maresch, Roman, Engleitner, Thomas, Gross, Nina, Geumann, Ulf, Fu, Beiyuan, Segler, Angela, Yuan, Detian, Lange, Sebastian, Strong, Alexander, de la Rosa, Jorge, Esposito, Irene, Liu, Pentao, Cadiñanos, Juan, Vassiliou, George S., Schmid, Roland M., Schneider, Günter, Unger, Kristian, Yang, Fengtang, Braren, Rickmer, Heikenwälder, Mathias, Varela, Ignacio, Saur, Dieter, Bradley, Allan, Rad, Roland
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.2015)
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Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice
Maresch, Roman, Mueller, Sebastian, Veltkamp, Christian, Öllinger, Rupert, Friedrich, Mathias, Heid, Irina, Steiger, Katja, Weber, Julia, Engleitner, Thomas, Barenboim, Maxim, Klein, Sabine, Louzada, Sandra, Banerjee, Ruby, Strong, Alexander, Stauber, Teresa, Gross, Nina, Geumann, Ulf, Lange, Sebastian, Ringelhan, Marc, Varela, Ignacio, Unger, Kristian, Yang, Fengtang, Schmid, Roland M, Vassiliou, George S, Braren, Rickmer, Schneider, Günter, Heikenwalder, Mathias, Bradley, Allan, Saur, Dieter, Rad, Roland
Published in Nature communications (26.02.2016)
Published in Nature communications (26.02.2016)
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A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer
Schönhuber, Nina, Seidler, Barbara, Schuck, Kathleen, Veltkamp, Christian, Schachtler, Christina, Zukowska, Magdalena, Eser, Stefan, Feyerabend, Thorsten B, Paul, Mariel C, Eser, Philipp, Klein, Sabine, Lowy, Andrew M, Banerjee, Ruby, Yang, Fangtang, Lee, Chang-Lung, Moding, Everett J, Kirsch, David G, Scheideler, Angelika, Alessi, Dario R, Varela, Ignacio, Bradley, Allan, Kind, Alexander, Schnieke, Angelika E, Rodewald, Hans-Reimer, Rad, Roland, Schmid, Roland M, Schneider, Günter, Saur, Dieter
Published in Nature medicine (01.11.2014)
Published in Nature medicine (01.11.2014)
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Gut bacterial dysbiosis and instability is associated with the onset of complications and mortality in COVID-19
Schult, David, Reitmeier, Sandra, Koyumdzhieva, Plamena, Lahmer, Tobias, Middelhoff, Moritz, Erber, Johanna, Schneider, Jochen, Kager, Juliane, Frolova, Marina, Horstmann, Julia, Fricke, Lisa, Steiger, Katja, Jesinghaus, Moritz, Janssen, Klaus-Peter, Protzer, Ulrike, Neuhaus, Klaus, Schmid, Roland M., Haller, Dirk, Quante, Michael
Published in Gut microbes (31.12.2022)
Published in Gut microbes (31.12.2022)
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gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis
Bollrath, Julia, Phesse, Toby J., von Burstin, Vivian A., Putoczki, Tracy, Bennecke, Moritz, Bateman, Trudie, Nebelsiek, Tim, Lundgren-May, Therese, Canli, Özge, Schwitalla, Sarah, Matthews, Vance, Schmid, Roland M., Kirchner, Thomas, Arkan, Melek C., Ernst, Matthias, Greten, Florian R.
Published in Cancer cell (03.02.2009)
Published in Cancer cell (03.02.2009)
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Hepatocellular Brg1 promotes CCl4-induced liver inflammation, ECM accumulation and fibrosis in mice
Wang, Baocai, Kaufmann, Benedikt, Mogler, Carolin, Zhong, Suyang, Yin, Yuhan, Cheng, Zhangjun, Schmid, Roland M, Friess, Helmut, Hüser, Norbert, von Figura, Guido, Hartmann, Daniel
Published in PloS one (30.11.2023)
Published in PloS one (30.11.2023)
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E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex
von Burstin, Johannes, Eser, Stefan, Paul, Mariel C, Seidler, Barbara, Brandl, Martina, Messer, Marlena, von Werder, Alexander, Schmidt, Annegret, Mages, Jörg, Pagel, Philipp, Schnieke, Angelika, Schmid, Roland M, Schneider, Günter, Saur, Dieter
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2009)
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2009)
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