Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4-AIO): results from the phase 2 part of a multicentre, open-label, randomised phase 2/3 trial
Al-Batran, Salah-Eddin, Prof, Hofheinz, Ralf D, Prof, Pauligk, Claudia, PhD, Kopp, Hans-Georg, MD, Haag, Georg Martin, MD, Luley, Kim Barbara, MD, Meiler, Johannes, MD, Homann, Nils, Prof, Lorenzen, Sylvie, MD, Schmalenberg, Harald, MD, Probst, Stephan, MD, Koenigsmann, Michael, Prof, Egger, Matthias, MD, Prasnikar, Nicole, MD, Caca, Karel, Prof, Trojan, Jörg, Prof, Martens, Uwe M, Prof, Block, Andreas, MD, Fischbach, Wolfgang, Prof, Mahlberg, Rolf, MD, Clemens, Michael, Prof, Illerhaus, Gerald, Prof, Zirlik, Katja, MD, Behringer, Dirk M, Prof, Schmiegel, Wolff, Prof, Pohl, Michael, MD, Heike, Michael, Prof, Ronellenfitsch, Ulrich, MD, Schuler, Martin, Prof, Bechstein, Wolf O, Prof, Königsrainer, Alfred, Prof, Gaiser, Timo, Prof, Schirmacher, Peter, Prof, Hozaeel, Wael, MD, Reichart, Alexander, MD, Goetze, Thorsten O, MD, Sievert, Mark, MD, Jäger, Elke, Prof, Mönig, Stefan, Prof, Tannapfel, Andrea, Prof
Published in The lancet oncology (01.12.2016)
Published in The lancet oncology (01.12.2016)
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The RENAISSANCE (AIO-FLOT5) trial: effect of chemotherapy alone vs. chemotherapy followed by surgical resection on survival and quality of life in patients with limited-metastatic adenocarcinoma of the stomach or esophagogastric junction - a phase III trial of the German AIO/CAO-V/CAOGI
Al-Batran, Salah-Eddin, Goetze, Thorsten O, Mueller, Daniel W, Vogel, Arndt, Winkler, Michael, Lorenzen, Sylvie, Novotny, Alexander, Pauligk, Claudia, Homann, Nils, Jungbluth, Thomas, Reissfelder, Christoph, Caca, Karel, Retter, Steffen, Horndasch, Eva, Gumpp, Julia, Bolling, Claus, Fuchs, Karl-Hermann, Blau, Wolfgang, Padberg, Winfried, Pohl, Michael, Wunsch, Andreas, Michl, Patrick, Mannes, Frank, Schwarzbach, Matthias, Schmalenberg, Harald, Hohaus, Michael, Scholz, Christian, Benckert, Christoph, Knorrenschild, Jorge Riera, Kanngießer, Veit, Zander, Thomas, Alakus, Hakan, Hofheinz, Ralf-Dieter, Roedel, Claus, Shah, Manish A, Sasako, Mitsuru, Lorenz, Dietmar, Izbicki, Jakob, Bechstein, Wolf O, Lang, Hauke, Moenig, Stefan P
Published in BMC cancer (28.12.2017)
Published in BMC cancer (28.12.2017)
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Phase III Trial in Metastatic Gastroesophageal Adenocarcinoma with Fluorouracil, Leucovorin Plus Either Oxaliplatin or Cisplatin: A Study of the Arbeitsgemeinschaft Internistische Onkologie
AL-BATRAN, Salah-Eddin, HARTMANN, Joerg Thomas, SCHUCH, Gunter, STOEHLMACHER, Jan, DERIGS, Hans Günter, HEGEWISCH-BECKER, Susanna, GROSSMANN, Johannes, PAULIGK, Claudia, ATMACA, Akin, BOKEMEYER, Carsten, KNUTH, Alexander, JÄGER, Elke, PROBST, Stephan, SCHMALENBERG, Harald, HOLLERBACH, Stephan, HOFHEINZ, Ralf, RETHWISCH, Volker, SEIPELT, Gernot, HOMANN, Nils, WILHELM, Gerhard
Published in Journal of clinical oncology (20.03.2008)
Published in Journal of clinical oncology (20.03.2008)
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Prognostic Role of Circulating Tumor Cells during Induction Chemotherapy Followed by Curative Surgery Combined with Postoperative Radiotherapy in Patients with Locally Advanced Oral and Oropharyngeal Squamous Cell Cancer
Inhestern, Johanna, Oertel, Katrin, Stemmann, Viola, Schmalenberg, Harald, Dietz, Andreas, Rotter, Nicole, Veit, Johannes, Görner, Martin, Sudhoff, Holger, Junghanß, Christian, Wittekindt, Claus, Pachmann, Katharina, Guntinas-Lichius, Orlando
Published in PloS one (17.07.2015)
Published in PloS one (17.07.2015)
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Docetaxel, oxaliplatin, and fluorouracil/leucovorin (FLOT) versus epirubicin, cisplatin, and fluorouracil or capecitabine (ECF/ECX) as perioperative treatment of resectable gastric or gastro-esophageal junction adenocarcinoma: The multicenter, randomized phase 3 FLOT4 trial (German Gastric Group at AIO)
Al-Batran, Salah-Eddin, Pauligk, Claudia, Homann, Nils, Schmalenberg, Harald, Kopp, Hans-Georg, Haag, Georg Martin, Luley Kim, Barbara, Schmiegel Wolff, H., Folprecht, Gunnar, Probst, Stephan, Prasnikar, Nicole, Thuss-Patience Peter, C., Trojan, Jorg, Goetze, Thorsten Oliver, Meiler, Johannes, Schuler Martin, H., Jäger, Elke, Hofheinz, Ralf-Dieter
Published in Annals of oncology (01.06.2017)
Published in Annals of oncology (01.06.2017)
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Phase I trial of split-dose induction docetaxel, cisplatin, and 5-fluorouracil (TPF) chemotherapy followed by curative surgery combined with postoperative radiotherapy in patients with locally advanced oral and oropharyngeal squamous cell cancer (TISOC-1)
Oertel, Katrin, Spiegel, Karin, Schmalenberg, Harald, Dietz, Andreas, Maschmeyer, Georg, Kuhnt, Thomas, Sudhoff, Holger, Wendt, Thomas G, Guntinas-Lichius, Orlando
Published in BMC cancer (20.10.2012)
Published in BMC cancer (20.10.2012)
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Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial
Al-Batran, Salah-Eddin, Homann, Nils, Pauligk, Claudia, Goetze, Thorsten O, Meiler, Johannes, Kasper, Stefan, Kopp, Hans-Georg, Mayer, Frank, Haag, Georg Martin, Luley, Kim, Lindig, Udo, Schmiegel, Wolff, Pohl, Michael, Stoehlmacher, Jan, Folprecht, Gunnar, Probst, Stephan, Prasnikar, Nicole, Fischbach, Wolfgang, Mahlberg, Rolf, Trojan, Jörg, Koenigsmann, Michael, Martens, Uwe M, Thuss-Patience, Peter, Egger, Matthias, Block, Andreas, Heinemann, Volker, Illerhaus, Gerald, Moehler, Markus, Schenk, Michael, Kullmann, Frank, Behringer, Dirk M, Heike, Michael, Pink, Daniel, Teschendorf, Christian, Löhr, Carmen, Bernhard, Helga, Schuch, Gunter, Rethwisch, Volker, von Weikersthal, Ludwig Fischer, Hartmann, Jörg T, Kneba, Michael, Daum, Severin, Schulmann, Karsten, Weniger, Jörg, Belle, Sebastian, Gaiser, Timo, Oduncu, Fuat S, Güntner, Martina, Hozaeel, Wael, Reichart, Alexander, Jäger, Elke, Kraus, Thomas, Mönig, Stefan, Bechstein, Wolf O, Schuler, Martin, Schmalenberg, Harald, Hofheinz, Ralf D
Published in The Lancet (British edition) (11.05.2019)
Published in The Lancet (British edition) (11.05.2019)
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Adjuvant Chemotherapy With Gemcitabine vs Observation in Patients Undergoing Curative-Intent Resection of Pancreatic Cancer: A Randomized Controlled Trial
Oettle, Helmut, Post, Stefan, Neuhaus, Peter, Gellert, Klaus, Langrehr, Jan, Ridwelski, Karsten, Schramm, Harald, Fahlke, Joerg, Zuelke, Carl, Burkart, Christof, Gutberlet, Klaus, Kettner, Erika, Schmalenberg, Harald, Weigang-Koehler, Karin, Bechstein, Wolf-Otto, Niedergethmann, Marco, Schmidt-Wolf, Ingo, Roll, Lars, Doerken, Bernd, Riess, Hanno
Published in JAMA : the journal of the American Medical Association (17.01.2007)
Published in JAMA : the journal of the American Medical Association (17.01.2007)
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Safety of preventive HIPEC in combination with perioperative FLOT versus FLOT alone for resectable diffuse type gastric and gastroesophageal junction type II/III adenocarcinoma: An interim safety analysis from the phase III PREVENT trial of the AIO/CAOGI/ACO
Goetze, Thorsten, Piso, Pompiliu, Bankstahl, Ulli Simone, Pauligk, Claudia, Volk, Claudia, Knapp, Fabienne, Sookthai, Disorn, Lorenzen, Sylvie, Schenk, Michael, Wiegering, Armin, Jo, Peter, Werner, Jens, Hölzen, Jens Peter, Stange, Daniel E, Stein, Alexander, Schmalenberg, Harald, Senkal, Metin, Al-Batran, Salah-Eddin
Published in Journal of clinical oncology (20.01.2024)
Published in Journal of clinical oncology (20.01.2024)
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Effect of Neoadjuvant Chemotherapy Followed by Surgical Resection on Survival in Patients With Limited Metastatic Gastric or Gastroesophageal Junction Cancer: The AIO-FLOT3 Trial
Al-Batran, Salah-Eddin, Homann, Nils, Pauligk, Claudia, Illerhaus, Gerald, Martens, Uwe M, Stoehlmacher, Jan, Schmalenberg, Harald, Luley, Kim B, Prasnikar, Nicole, Egger, Matthias, Probst, Stephan, Messmann, Helmut, Moehler, Markus, Fischbach, Wolfgang, Hartmann, Jörg T, Mayer, Frank, Höffkes, Heinz-Gert, Koenigsmann, Michael, Arnold, Dirk, Kraus, Thomas W, Grimm, Kersten, Berkhoff, Stefan, Post, Stefan, Jäger, Elke, Bechstein, Wolf, Ronellenfitsch, Ulrich, Mönig, Stefan, Hofheinz, Ralf D
Published in JAMA oncology (01.09.2017)
Published in JAMA oncology (01.09.2017)
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FLOT plus nivolumab in patients with previously untreated advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junction: Results from the randomized phase 2 IKF-S628/AIO-STO-0417 (Moonlight) trial of the AIO
Lorenzen, Sylvie, Goetze, Thorsten Oliver, Hofheinz, Ralf Dieter, Thuss-Patience, Peter C., Dechow, Tobias Nicolaas, Riera-Knorrenschild, Jorge, Schuch, Gunter, Luley, Kim Barbara, Koch, Christine, Goekkurt, Eray, Schmalenberg, Harald, Ettrich, Thomas Jens, Lindig, Udo, Pink, Daniel, Bitzer, Michael, Bolling, Claus, Homann, Nils, Junge, Sabine, Pauligk, Claudia, Al-Batran, Salah-Eddin
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Paclitaxel + ramucirumab versus paclitaxel alone in patients with squamous-cell carcinoma of the esophagus, refractory or intolerant to combination therapy with fluoropyrimidine and platinum-based drugs: Final results from the randomized phase 2 IKF-S627/RAMOS trial of the AIO
Scheck, Magdalena, Goetze, Thorsten Oliver, Ettrich, Thomas Jens, Schmalenberg, Harald, Clemens, Michael, Mahlberg, Rolf, Heeg, Steffen, Kanzler, Stephan, Hapke, Gunnar, Thuss-Patience, Peter C., Kestler, Angelika, Treschl, Anne, Frost, Gregg, Schiemer, Moritz, Junge, Sabine, Pauligk, Claudia, Al-Batran, Salah-Eddin, Lorenzen, Sylvie
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Perioperative FLOT plus ramucirumab for resectable esophagogastric adenocarcinoma: A randomized phase II/III trial of the German AIO and Italian GOIM
Goetze, Thorsten O., Hofheinz, Ralf‐Dieter, Gaiser, Timo, Schmalenberg, Harald, Strumberg, Dirk, Goekkurt, Eray, Angermeier, Stefan, Zander, Thomas, Kopp, Hans G., Pink, Daniel, Siegler, Gabriele, Schenk, Michael, Vita, Ferdinando, Galizia, Gennaro, Maiello, Evaristo, Bechstein, Wolf O., Elshafei, Moustafa, Loose, Maria, Sookthai, Disorn, Brulin, Tanita, Pauligk, Claudia, Homann, Nils, Al‐Batran, Salah‐Eddin
Published in International journal of cancer (01.07.2023)
Published in International journal of cancer (01.07.2023)
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Perioperative ramucirumab in combination with FLOT versus FLOT alone for resectable esophagogastric adenocarcinoma (RAMSES/FLOT7) with high rate of signet cell component: Final results of the multicenter, randomized phase II/III trial of the German AIO and Italian GOIM
Goetze, Thorsten Oliver, Hofheinz, Ralf-Dieter, Schmalenberg, Harald, Strumberg, Dirk, Goekkurt, Eray, Angermeier, Stefan, Zander, Thomas, Potenberg, Jochem, Kopp, Hans-Georg, Pink, Daniel, Siegler, Gabriele Margareta, Schenk, Michael, De Vita, Ferdinando, Maiello, Evaristo, Gaiser, Timo, Sookthai, Disorn, Brulin, Tanita, Pauligk, Claudia, Homann, Nils, Al-Batran, Salah-Eddin
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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PD-L1 mRNA expression in patients with resectable gastric cancer and adenocarcinoma of the oesophago-gastric junction undergoing perioperative chemotherapy: Results from the FLOT4 phase III trial of the AIO
Waberer, Lisa, Homann, Nils, Wirtz, Ralph M, Schmalenberg, Harald, Haag, Georg Martin, Schuler, Martin H., Kasper, Stefan, Goetze, Thorsten Oliver, Pauligk, Claudia, Hofheinz, Ralf, Al-Batran, Salah-Eddin
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Perioperative atezolizumab in combination with FLOT versus FLOT alone in patients with resectable esophagogastric adenocarcinoma: DANTE, a randomized, open-label phase II trial of the German Gastric Group of the AIO and the SAKK
Al-Batran, Salah-Eddin, Pauligk, Claudia, Hofheinz, Ralf, Lorenzen, Sylvie, Wicki, Andreas, Siebenhuener, Alexander Rheinhard, Schenk, Michael, Welslau, Manfred, Heuer, Vera, Goekkurt, Eray, Schmalenberg, Harald, Thuss-Patience, Peter C., Waberer, Lisa, Talbot, Jonathan, Goetze, Thorsten Oliver, Homann, Nils
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Paclitaxel/Ramucirumab versus Paclitaxel in 2nd-Line Therapy of Advanced Esophageal Squamous Cell Carcinoma: Randomized Phase II IKF-AIO-RAMOS Trial
Scheck, Magdalena K, Goetze, Thorsten O, Ettrich, Thomas J, Schmalenberg, Harald, Clemens, Michael, Mahlberg, Rolf, Heeg, Steffen, Kanzler, Stephan, Hapke, Gunnar, Thuss-Patience, Peter, Kestler, Angelika, Treschl, Anne, Heidel, Stefan, Schiemer, Moritz, Sookthai, Disorn, Junge, Sabine, Pauligk, Claudia, Al-Batran, Salah-Eddin, Lorenzen, Sylvie
Published in Oncology research and treatment (2024)
Published in Oncology research and treatment (2024)
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Perioperative ramucirumab in combination with FLOT versus FLOT alone for resectable esophagogastric adenocarcinoma (RAMSES/FLOT7): Results of the phase II-portion—A multicenter, randomized phase II/III trial of the German AIO and Italian GOIM
Al-Batran, Salah-Eddin, Hofheinz, Ralf Dieter, Schmalenberg, Harald, Strumberg, Dirk, Goekkurt, Eray, Angermeier, Stefan, Zander, Thomas, Potenberg, Jochem, Kopp, Hans Georg, Pink, Daniel, Siegler, Gabriele Margareta, Schenk, Michael, De Vita, Ferdinando, Maiello, Evaristo, Gaiser, Timo, Sookthai, Disorn, Bankstahl, Ulli Simone, Pauligk, Claudia, Goetze, Thorsten Oliver, Homann, Nils
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Interim safety analysis of the DANTE trial: Perioperative atezolizumab in combination with FLOT versus FLOT alone in patients with resectable esophagogastric adenocarcinoma—A randomized, open-label phase II trial of the German Gastric Group at the AIO and SAKK
Homann, Nils, Lorenzen, Sylvie, Schenk, Michael, Thuss-Patience, Peter C., Goekkurt, Eray, Hofheinz, Ralf Dieter, Kretzschmar, Albrecht, Bolling, Claus, Angermeier, Stefan, Wicki, Andreas, Siebenhuener, Alexander Rheinhard, Lindig, Udo, Pink, Daniel, Ettrich, Thomas Jens, Schmalenberg, Harald, Waberer, Lisa, Talbot, Jonathan, Pauligk, Claudia, Goetze, Thorsten Oliver, Al-Batran, Salah-Eddin
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Safety of perioperative atezolizumab in combination with FLOT versus FLOT alone in patients with resectable esophagogastric adenocarcinoma: An interim safety analysis of the DANTE, a randomized, open-label phase II trial of the German Gastric Group at the AIO and the SAKK
Al-Batran, Salah-Eddin, Lorenzen, Sylvie, Schenk, Michael, Thuss-Patience, Peter C., Goekkurt, Eray, Hofheinz, Ralf, Kretzschmar, Albrecht, Bolling, Claus, Angermeier, Stefan, Wicki, Andreas, Siebenhuener, Alexander Rheinhard, Eigendorff, Ekkehard, Pink, Christin, Ettrich, Thomas Jens, Schmalenberg, Harald, Waberer, Lisa, Talbot, Jonathan, Pauligk, Claudia, Goetze, Thorsten Oliver, Homann, Nils
Published in Journal of clinical oncology (01.02.2020)
Published in Journal of clinical oncology (01.02.2020)
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