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Hazuda, Daria J., Young, Steven D., Guare, James P., Anthony, Neville J., Gomez, Robert P., Wai, John S., Vacca, Joseph P., Handt, Larry, Motzel, Sherri L., Klein, Hilton J., Dornadula, Geethanjali, Danovich, Robert M., Witmer, Marc V., Keith A. A. Wilson, Tussey, Lynda, Schleif, William A., Gabryelski, Lori S., Jin, Lixia, Miller, Michael D., Casimiro, Danilo R., Emini, Emilio A., Shiver, John W.
Published in Science (American Association for the Advancement of Science) (23.07.2004)
Published in Science (American Association for the Advancement of Science) (23.07.2004)
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Design and Synthesis of 8-Hydroxy-[1,6]Naphthyridines as Novel Inhibitors of HIV-1 Integrase in Vitro and in Infected Cells
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Published in Journal of medicinal chemistry (13.02.2003)
Published in Journal of medicinal chemistry (13.02.2003)
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Covalent Stabilization of Coiled Coils of the HIV gp41 N Region Yields Extremely Potent and Broad Inhibitors of Viral Infection
Bianchi, Elisabetta, Finotto, Marco, Ingallinella, Paolo, Hrin, Renee, Carella, Anthony V., Hou, Xiaoli S., Schleif, William A., Miller, Michael D., Geleziunas, Romas, Pessi, Antonello, Gallo, Robert C.
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Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2005)
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Potent 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists: effects of fused heterocycles on antiviral activity and pharmacokinetic properties
Kim, Dooseop, Wang, Liping, Hale, Jeffrey J., Lynch, Christopher L., Budhu, Richard J., MacCoss, Malcolm, Mills, Sander G., Malkowitz, Lorraine, Gould, Sandra L., DeMartino, Julie A., Springer, Martin S., Hazuda, Daria, Miller, Michael, Kessler, Joseph, Hrin, Renee C., Carver, Gwen, Carella, Anthony, Henry, Karen, Lineberger, Janet, Schleif, William A., Emini, Emilio A.
Published in Bioorganic & medicinal chemistry letters (15.04.2005)
Published in Bioorganic & medicinal chemistry letters (15.04.2005)
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Efficacy of Multivalent Adenovirus-Based Vaccine against Simian Immunodeficiency Virus Challenge
CASIMIRO, Danilo R, COX, Kara, TOBERY, Timothy W, WILSON, Keith, FINNEFROCK, Adam, LINGYI HUANG, VITELLI, Salvatore, JING LIN, PATEL, Deepa, DAVIES, Mary-Ellen, HEIDECKER, Gwendolyn J, FREED, Daniel C, AIMIN TANG, DUBEY, Sheri, O'CONNOR, David H, WATKINS, David I, ZHANG, Zhi-Qiang, SHIVER, John W, SYKES, Kara J, MEIZHEN FENG, FUBAO WANG, BETT, Andrew, SCHLEIF, William A, XIAOPING LIANG, FLYNN, Jessica
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Published in Journal of Virology (01.03.2010)
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Drug Resistance and Predicted Virologic Responses to Human Immunodeficiency Virus Type 1 Protease Inhibitor Therapy
Condra, Jon H., Petropoulos, Christos J., Ziermann, Rainer, Schleif, William A., Shivaprakash, Malathi, Emini, Emilio A.
Published in The Journal of infectious diseases (01.09.2000)
Published in The Journal of infectious diseases (01.09.2000)
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Vectored Gag and Env but Not Tat Show Efficacy against Simian-Human Immunodeficiency Virus 89.6P Challenge in Mamu-A01-Negative Rhesus Monkeys
Liang, Xiaoping, Casimiro, Danilo R, Schleif, William A, Wang, Fubao, Davies, Mary-Ellen, Zhang, Zhi-Qiang, Fu, Tong-Ming, Finnefrock, Adam C, Handt, Larry, Citron, Michael P, Heidecker, Gwendolyn, Tang, Aimin, Chen, Minchun, Wilson, Keith A, Gabryelski, Lori, McElhaugh, Michael, Carella, Anthony, Moyer, Cheryl, Huang, Lingyi, Vitelli, Salvatore, Patel, Deepa, Lin, Jing, Emini, Emilio A, Shiver, John W
Published in Journal of Virology (01.10.2005)
Published in Journal of Virology (01.10.2005)
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Early depletion of proliferating B cells of germinal center in rapidly progressive simian immunodeficiency virus infection
Zhang, Zhi-Qiang, Casimiro, Danilo R, Schleif, William A, Chen, Minchun, Citron, Michael, Davies, Mary-Ellen, Burns, Janine, Liang, Xiaoping, Fu, Tong-Ming, Handt, Larry, Emini, Emilio A, Shiver, John W
Published in Virology (New York, N.Y.) (10.05.2007)
Published in Virology (New York, N.Y.) (10.05.2007)
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Mamu-A01 Allele-Mediated Attenuation of Disease Progression in Simian-Human Immunodeficiency Virus Infection
Zhang, Zhi-Qiang, Fu, Tong-Ming, Casimiro, Danilo R, Davies, Mary-Ellen, Liang, Xiaoping, Schleif, William A, Handt, Larry, Tussey, Lynda, Chen, Minchun, Tang, Aimin, Wilson, Keith A, Trigona, Wendy L, Freed, Daniel C, Tan, Charles Y, Horton, Melanie, Emini, Emilio A, Shiver, John W
Published in Journal of Virology (01.12.2002)
Published in Journal of Virology (01.12.2002)
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A series of 5-(5,6)-dihydrouracil substituted 8-hydroxy-[1,6]naphthyridine-7-carboxylic acid 4-fluorobenzylamide inhibitors of HIV-1 integrase and viral replication in cells
Embrey, Mark W., Wai, John S., Funk, Timothy W., Homnick, Carl F., Perlow, Debbie S., Young, Steven D., Vacca, Joseph P., Hazuda, Daria J., Felock, Peter J., Stillmock, Kara A., Witmer, Marc V., Moyer, Gregory, Schleif, William A., Gabryelski, Lori J., Jin, Lixia, Chen, I-Wu, Ellis, Joan D., Wong, Bradley K., Lin, Jiunn H., Leonard, Yvonne M., Tsou, Nancy N., Zhuang, Linghang
Published in Bioorganic & medicinal chemistry letters (15.10.2005)
Published in Bioorganic & medicinal chemistry letters (15.10.2005)
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Cytotoxic T-Lymphocyte Escape Does Not Always Explain the Transient Control of Simian Immunodeficiency Virus SIVmac239 Viremia in Adenovirus-Boosted and DNA-Primed Mamu-A01-Positive Rhesus Macaques
MCDERMOTT, Adrian B, O'CONNOR, David H, RIEK, Cara, DODDS, Elizabeth, KREBS, Kendall, DAVIES, Mary-Ellen, SCHLEIF, William A, CASIMIRO, Danilo R, SHIVER, John W, WATKINS, D. I, FUENGER, Sarah, PIASKOWSKI, Shari, MARTIN, Sarah, LOFFREDO, John, REYNOLDS, Matthew, REED, Jason, FURLOTT, Jessica, JACOBY, Timothy
Published in Journal of Virology (01.12.2005)
Published in Journal of Virology (01.12.2005)
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Antagonists of human CCR5 receptor containing 4-(pyrazolyl)piperidine side chains. Part 1: Discovery and sar study of 4-pyrazolylpiperidine side chains
SHEN, Dong-Ming, MIN SHU, CARELLA, Anthony, CARVER, Gwen, HOLMES, Karen, SCHLEIF, William A, DANZEISEN, Renee, HAZUDA, Daria, KESSLER, Joseph, LINEBERGER, Janet, MILLER, Michael D, EMINI, Emilio A, MILLS, Sander G, CHAPMAN, Kevin T, MALKOWITZ, Lorraine, SPRINGER, Martin S, GOULD, Sandra L, DEMARTINO, Julie A, SICILIANO, Salvatore J, KWEI, Gloria Y
Published in Bioorganic & medicinal chemistry letters (23.02.2004)
Published in Bioorganic & medicinal chemistry letters (23.02.2004)
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The effect of early versus delayed challenge after vaccination in controlling SHIV 89.6P infection
Chavez, Leslie L, Davenport, Miles P, Shiver, John W, Tussey, Lynda G, Cox, Kara S, Bachinsky, Margaret, Wang, Fubao, Huang, Lingyi, Schleif, William A, Davies, Mary-Ellen, Tang, Aimin, Casimiro, Danilo R, Perelson, Alan S, Ribeiro, Ruy M
Published in Virology (New York, N.Y.) (10.11.2008)
Published in Virology (New York, N.Y.) (10.11.2008)
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Discovery of human CCR5 antagonists containing hydantoins for the treatment of HIV-1 infection
Kim, Dooseop, Wang, Liping, Caldwell, Charles G., Chen, Ping, Finke, Paul E., Oates, Bryan, MacCoss, Malcolm, Mills, Sander G., Malkowitz, Lorraine, Gould, Sandra L., DeMartino, Julie A., Springer, Martin S., Hazuda, Daria, Miller, Michael, Kessler, Joseph, Danzeisen, Renee, Carver, Gwen, Carella, Anthony, Holmes, Karen, Lineberger, Janet, Schleif, William A., Emini, Emilio A.
Published in Bioorganic & medicinal chemistry letters (17.12.2001)
Published in Bioorganic & medicinal chemistry letters (17.12.2001)
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Attenuation of Simian Immunodeficiency Virus SIVmac239 Infection by Prophylactic Immunization with DNA and Recombinant Adenoviral Vaccine Vectors Expressing Gag
CASIMIRO, Danilo R, FUBAO WANG, BAGCHI, Ansu, TUSSEY, Lynda G, BETT, Andrew J, FINNEFROCK, Adam C, FU, Tong-Ming, AIMIN TANG, WILSON, Keith A, MINCHUN CHEN, PERRY, Helen C, HEIDECKER, Gwendolyn J, SCHLEIF, William A, FREED, Daniel C, CARELLA, Anthony, PUNT, Kara S, SYKES, Kara J, LINGYI HUANG, AUSENSI, Virginia I, BACHINSKY, Margaret, SADASIVAN-NAIR, Usha, WATKINS, David I, EMINI, Emilio A, XIAOPING LIANG, SHIVER, John W, ZHANG, Zhi-Qiang, TOBERY, Timothy W, DAVIES, Mary-Ellen, MCDERMOTT, Adrian B, O'CONNOR, David H, FRIDMAN, Arthur
Published in Journal of Virology (01.12.2005)
Published in Journal of Virology (01.12.2005)
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Chemistry and Structure−Activity Relationship of HIV-1 Integrase Inhibitor Integracide B and Related Natural Products
Singh, Sheo B, Ondeyka, John G, Schleif, William A, Felock, Peter, Hazuda, Daria J
Published in Journal of natural products (Washington, D.C.) (01.10.2003)
Published in Journal of natural products (Washington, D.C.) (01.10.2003)
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Treatment with Indinavir, Zidovudine, and Lamivudine in Adults with Human Immunodeficiency Virus Infection and Prior Antiretroviral Therapy
Gulick, Roy M, Mellors, John W, Havlir, Diane, Eron, Joseph J, Gonzalez, Charles, McMahon, Deborah, Richman, Douglas D, Valentine, Fred T, Jonas, Leslie, Meibohm, Anne, Emini, Emilio A, Chodakewitz, Jeffrey A, Deutsch, Paul, Holder, Daniel, Schleif, William A, Condra, Jon H
Published in The New England journal of medicine (11.09.1997)
Published in The New England journal of medicine (11.09.1997)
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Nonpeptidal P2 Ligands for HIV Protease Inhibitors: Structure-Based Design, Synthesis, and Biological Evaluation
Ghosh, Arun K, Kincaid, John F, Walters, D. Eric, Chen, Yan, Chaudhuri, Narayan C, Thompson, Wayne J, Culberson, Chris, Fitzgerald, Paula M. D, Lee, Hee Yoon, McKee, Sean P, Munson, Peter M, Duong, Tien T, Darke, Paul L, Zugay, Joan A, Schleif, William A, Axel, Melinda G, Lin, Juinn, Huff, Joel R
Published in Journal of medicinal chemistry (16.08.1996)
Published in Journal of medicinal chemistry (16.08.1996)
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L-735,524: The Design of a Potent and Orally Bioavailable HIV Protease Inhibitor
Dorsey, Bruce D, Levin, Rhonda B, McDaniel, Stacy L, Vacca, Joseph P, Guare, James P, Darke, Paul L, Zugay, Joan A, Emini, Emilio A, Schleif, William A
Published in Journal of medicinal chemistry (01.10.1994)
Published in Journal of medicinal chemistry (01.10.1994)
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In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors
Condra, Jon H, Schleif, William A, Blahy, Olga M, Gabryelski, Lori J, Graham, Donald J, Quintero, Julio, Rhodes, Audrey, Robbins, Helen L, Roth, Elizabeth, Shivaprakash, Malathi, Titus, Donna, Yang, Tao, Tepplert, Hedy, Squires, Kathleen E, Deutsch, Paul J, Emini, Emilio A
Published in Nature (London) (06.04.1995)
Published in Nature (London) (06.04.1995)
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