The Crystal Structure of Human Argonaute2
Schirle, Nicole T., MacRae, Ian J.
Published in Science (American Association for the Advancement of Science) (25.05.2012)
Published in Science (American Association for the Advancement of Science) (25.05.2012)
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Journal Article
Structural basis for microRNA targeting
Schirle, Nicole T., Sheu-Gruttadauria, Jessica, MacRae, Ian J.
Published in Science (American Association for the Advancement of Science) (31.10.2014)
Published in Science (American Association for the Advancement of Science) (31.10.2014)
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Journal Article
Structural Basis for Target-Directed MicroRNA Degradation
Sheu-Gruttadauria, Jessica, Pawlica, Paulina, Klum, Shannon M., Wang, Sonia, Yario, Therese A., Schirle Oakdale, Nicole T., Steitz, Joan A., MacRae, Ian J.
Published in Molecular cell (19.09.2019)
Published in Molecular cell (19.09.2019)
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Journal Article
A Dynamic Search Process Underlies MicroRNA Targeting
Chandradoss, Stanley D., Schirle, Nicole T., Szczepaniak, Malwina, MacRae, Ian J., Joo, Chirlmin
Published in Cell (02.07.2015)
Published in Cell (02.07.2015)
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Journal Article
The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins
Shurtleff, Matthew J, Itzhak, Daniel N, Hussmann, Jeffrey A, Schirle Oakdale, Nicole T, Costa, Elizabeth A, Jonikas, Martin, Weibezahn, Jimena, Popova, Katerina D, Jan, Calvin H, Sinitcyn, Pavel, Vembar, Shruthi S, Hernandez, Hilda, Cox, Jürgen, Burlingame, Alma L, Brodsky, Jeffrey L, Frost, Adam, Borner, Georg Hh, Weissman, Jonathan S
Published in eLife (29.05.2018)
Published in eLife (29.05.2018)
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Journal Article
Helix‐7 in Argonaute2 shapes the microRNA seed region for rapid target recognition
Klum, Shannon M, Chandradoss, Stanley D, Schirle, Nicole T, Joo, Chirlmin, MacRae, Ian J
Published in The EMBO journal (04.01.2018)
Published in The EMBO journal (04.01.2018)
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Journal Article
Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets
Schirle, Nicole T, Sheu-Gruttadauria, Jessica, Chandradoss, Stanley D, Joo, Chirlmin, MacRae, Ian J
Published in eLife (11.09.2015)
Published in eLife (11.09.2015)
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Journal Article
Structure-Guided Control of siRNA Off-Target Effects
Suter, Scott R, Sheu-Gruttadauria, Jessica, Schirle, Nicole T, Valenzuela, Rachel, Ball-Jones, Alexi A, Onizuka, Kazumitsu, MacRae, Ian J, Beal, Peter A
Published in Journal of the American Chemical Society (20.07.2016)
Published in Journal of the American Chemical Society (20.07.2016)
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Journal Article
Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients
Miller-Vedam, Lakshmi E, Bräuning, Bastian, Popova, Katerina D, Schirle Oakdale, Nicole T, Bonnar, Jessica L, Prabu, Jesuraj R, Boydston, Elizabeth A, Sevillano, Natalia, Shurtleff, Matthew J, Stroud, Robert M, Craik, Charles S, Schulman, Brenda A, Frost, Adam, Weissman, Jonathan S
Published in eLife (25.11.2020)
Published in eLife (25.11.2020)
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Journal Article
Screening helix-threading peptides for RNA binding using a thiazole orange displacement assay
Krishnamurthy, Malathy, Schirle, Nicole T., Beal, Peter A.
Published in Bioorganic & medicinal chemistry (01.10.2008)
Published in Bioorganic & medicinal chemistry (01.10.2008)
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Journal Article
Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets - See more at: http://elifesciences.org/content/early/2015/09/11/eLife.07646#sthash.CUHzGKUq.dpuf
Schirle, Nicole T., Sheu-Gruttadauria, Jessica, Chandradoss, Stanley D., Joo, Chirlmin, MacRae, Ian J.
Published in eLife (30.06.2016)
Published in eLife (30.06.2016)
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Journal Article
Structural Basis for Target-Directed MicroRNA Degradation
Sheu-Gruttadauria, Jessica, Pawlica, Paulina, Klum, Shannon M., Wang, Sonia, Yario, Therese A., Schirle Oakdale, Nicole T., Steitz, Joan A., MacRae, Ian J.
Published in Molecular cell (01.09.2019)
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Published in Molecular cell (01.09.2019)
Journal Article