Hepatocyte hopping of OATP1B substrates contributes to efficient hepatic detoxification
Iusuf, D, van de Steeg, E, Schinkel, A H
Published in Clinical pharmacology and therapeutics (01.11.2012)
Published in Clinical pharmacology and therapeutics (01.11.2012)
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Effects of cytochrome P450 3A (CYP3A) and the drug transporters P‐glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir
van Waterschoot, RAB, ter Heine, R, Wagenaar, E, van der Kruijssen, CMM, Rooswinkel, RW, Huitema, ADR, Beijnen, JH, Schinkel, AH
Published in British journal of pharmacology (01.07.2010)
Published in British journal of pharmacology (01.07.2010)
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Oral co-administration of elacridar and ritonavir enhances plasma levels of oral paclitaxel and docetaxel without affecting relative brain accumulation
Hendrikx, J J M A, Lagas, J S, Wagenaar, E, Rosing, H, Schellens, J H M, Beijnen, J H, Schinkel, A H
Published in British journal of cancer (27.05.2014)
Published in British journal of cancer (27.05.2014)
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Development and validation of a quantitative assay for the determination of tamoxifen and its five main phase I metabolites in human serum using liquid chromatography coupled with tandem mass spectrometry
Teunissen, S.F., Jager, N.G.L., Rosing, H., Schinkel, A.H., Schellens, J.H.M., Beijnen, J.H.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.06.2011)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.06.2011)
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Bioanalytical methods for determination of tamoxifen and its phase I metabolites: A review
Teunissen, S.F., Rosing, H., Schinkel, A.H., Schellens, J.H.M., Beijnen, J.H.
Published in Analytica chimica acta (17.12.2010)
Published in Analytica chimica acta (17.12.2010)
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Quantification of docetaxel and its metabolites in human plasma by liquid chromatography/tandem mass spectrometry
Hendrikx, J. J. M. A., Dubbelman, A. C., Rosing, H., Schinkel, A. H., Schellens, J. H. M., Beijnen, J. H.
Published in Rapid communications in mass spectrometry (15.09.2013)
Published in Rapid communications in mass spectrometry (15.09.2013)
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Development and validation of a quantitative assay for the analysis of tamoxifen with its four main metabolites and the flavonoids daidzein, genistein and glycitein in human serum using liquid chromatography coupled with tandem mass spectrometry
Teunissen, S.F., Rosing, H., Koornstra, R.H.T., Linn, S.C., Schellens, J.H.M., Schinkel, A.H., Beijnen, J.H.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.08.2009)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.08.2009)
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Carcinogen and Anticancer Drug Transport by Mrp2 in Vivo: Studies Using Mrp2 (Abcc2) Knockout Mice
Vlaming, M L H, Mohrmann, K, Wagenaar, E, de Waart, D R, Elferink, R P J Oude, Lagas, J S, van Tellingen, O, Vainchtein, L D, Rosing, H, Beijnen, J H, Schellens, J H M, Schinkel, A H
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
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Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA
Evers, R, Kool, M, van Deemter, L, Janssen, H, Calafat, J, Oomen, L C, Paulusma, C C, Oude Elferink, R P, Baas, F, Schinkel, A H, Borst, P
Published in The Journal of clinical investigation (01.04.1998)
Published in The Journal of clinical investigation (01.04.1998)
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Investigational study of tamoxifen phase I metabolites using chromatographic and spectroscopic analytical techniques
Teunissen, S.F., Rosing, H., Seoane, M. Dominguez, Brunsveld, L., Schellens, J.H.M., Schinkel, A.H., Beijnen, J.H.
Published in Journal of pharmaceutical and biomedical analysis (01.06.2011)
Published in Journal of pharmaceutical and biomedical analysis (01.06.2011)
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Development and validation of a liquid chromatography–tandem mass spectrometry assay for the analysis of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) and its metabolite 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5- b]pyridine (N-OH-PhIP) in plasma, urine, bile, intestinal contents, faeces and eight selected tissues from mice
Teunissen, S.F., Vlaming, M.L.H., Rosing, H., Schellens, J.H.M., Schinkel, A.H., Beijnen, J.H.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.09.2010)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.09.2010)
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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
Schinkel, A.H., Smit, J.J.M., van Tellingen, O., Beijnen, J.H., Wagenaar, E., van Deemter, L., Mol, C.A.A.M., van der Valk, M.A., Robanus-Maandag, E.C., te Riele, H.P.J., Berns, A.J.M., Borst, P.
Published in Cell (20.05.1994)
Published in Cell (20.05.1994)
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Review on the analysis of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine and its phase I and phase II metabolites in biological matrices, foodstuff and beverages
Teunissen, S.F., Rosing, H., Schinkel, A.H., Schellens, J.H.M., Beijnen, J.H.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.12.2010)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.12.2010)
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Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes
Zwart, R, Sleutels, F, Wutz, A, Schinkel, A H, Barlow, D P
Published in Genes & development (15.09.2001)
Published in Genes & development (15.09.2001)
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