A 17-gene stemness score for rapid determination of risk in acute leukaemia
Ng, Stanley W. K., Mitchell, Amanda, Kennedy, James A., Chen, Weihsu C., McLeod, Jessica, Ibrahimova, Narmin, Arruda, Andrea, Popescu, Andreea, Gupta, Vikas, Schimmer, Aaron D., Schuh, Andre C., Yee, Karen W., Bullinger, Lars, Herold, Tobias, Görlich, Dennis, Büchner, Thomas, Hiddemann, Wolfgang, Berdel, Wolfgang E., Wörmann, Bernhard, Cheok, Meyling, Preudhomme, Claude, Dombret, Hervé, Metzeler, Klaus, Buske, Christian, Löwenberg, Bob, Valk, Peter J. M., Zandstra, Peter W., Minden, Mark D., Dick, John E., Wang, Jean C. Y.
Published in Nature (London) (15.12.2016)
Published in Nature (London) (15.12.2016)
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Journal Article
Venetoclax resistance in acute myeloid leukaemia—Clinical and biological insights
Nachmias, Boaz, Aumann, Shlomzion, Haran, Arnon, Schimmer, Aaron D.
Published in British journal of haematology (01.04.2024)
Published in British journal of haematology (01.04.2024)
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Journal Article
Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response
Sharon, David, Cathelin, Severine, Mirali, Sara, Di Trani, Justin M, Yanofsky, David J, Keon, Kristine A, Rubinstein, John L, Schimmer, Aaron D, Ketela, Troy, Chan, Steven M
Published in Science translational medicine (30.10.2019)
Published in Science translational medicine (30.10.2019)
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Journal Article
Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia
Škrtić, Marko, Sriskanthadevan, Shrivani, Jhas, Bozhena, Gebbia, Marinella, Wang, Xiaoming, Wang, Zezhou, Hurren, Rose, Jitkova, Yulia, Gronda, Marcela, Maclean, Neil, Lai, Courteney K., Eberhard, Yanina, Bartoszko, Justyna, Spagnuolo, Paul, Rutledge, Angela C., Datti, Alessandro, Ketela, Troy, Moffat, Jason, Robinson, Brian H., Cameron, Jessie H., Wrana, Jeffery, Eaves, Connie J., Minden, Mark D., Wang, Jean C.Y., Dick, John E., Humphries, Keith, Nislow, Corey, Giaever, Guri, Schimmer, Aaron D.
Published in Cancer cell (15.11.2011)
Published in Cancer cell (15.11.2011)
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Journal Article
Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality
Ishizawa, Jo, Zarabi, Sarah F., Davis, R. Eric, Halgas, Ondrej, Nii, Takenobu, Jitkova, Yulia, Zhao, Ran, St-Germain, Jonathan, Heese, Lauren E., Egan, Grace, Ruvolo, Vivian R., Barghout, Samir H., Nishida, Yuki, Hurren, Rose, Ma, Wencai, Gronda, Marcela, Link, Todd, Wong, Keith, Mabanglo, Mark, Kojima, Kensuke, Borthakur, Gautam, MacLean, Neil, Ma, Man Chun John, Leber, Andrew B., Minden, Mark D., Houry, Walid, Kantarjian, Hagop, Stogniew, Martin, Raught, Brian, Pai, Emil F., Schimmer, Aaron D., Andreeff, Michael
Published in Cancer cell (13.05.2019)
Published in Cancer cell (13.05.2019)
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Journal Article
Novel Proteasome Inhibitors to Overcome Bortezomib Resistance
Ruschak, Amy M., Slassi, Malik, Kay, Lewis E., Schimmer, Aaron D.
Published in JNCI : Journal of the National Cancer Institute (06.07.2011)
Published in JNCI : Journal of the National Cancer Institute (06.07.2011)
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Journal Article
Venetoclax enhances T cell–mediated antileukemic activity by increasing ROS production
Lee, Jong Bok, Khan, Dilshad H., Hurren, Rose, Xu, Mingjing, Na, Yoosu, Kang, Hyeonjeong, Mirali, Sara, Wang, Xiaoming, Gronda, Marcela, Jitkova, Yulia, MacLean, Neil, Arruda, Andrea, Alaniz, Zoe, Konopleva, Marina Y., Andreeff, Michael, Minden, Mark D., Zhang, Li, Schimmer, Aaron D.
Published in Blood (22.07.2021)
Published in Blood (22.07.2021)
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Journal Article
Very long chain fatty acid metabolism is required in acute myeloid leukemia
Tcheng, Matthew, Roma, Alessia, Ahmed, Nawaz, Smith, Richard W., Jayanth, Preethi, Minden, Mark D., Schimmer, Aaron D., Hess, David A., Hope, Kristin, Rea, Kevin A., Akhtar, Tariq A., Bohrnsen, Eric, D'Alessandro, Angelo, Mohsen, Al-Walid, Vockley, Jerry, Spagnuolo, Paul A.
Published in Blood (24.06.2021)
Published in Blood (24.06.2021)
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Journal Article
A multicenter phase I/II study of obatoclax mesylate administered as a 3- or 24-hour infusion in older patients with previously untreated acute myeloid leukemia
Schimmer, Aaron D, Raza, Azra, Carter, Thomas H, Claxton, David, Erba, Harry, DeAngelo, Daniel J, Tallman, Martin S, Goard, Carolyn, Borthakur, Gautam
Published in PloS one (06.10.2014)
Published in PloS one (06.10.2014)
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