Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells
FRANKE, N. E, NIEWERTH, D, SCHIMMER, A. D, KASPERS, Gjl, JANSEN, G, CLOOS, J, ASSARAF, Y. G, VAN MEERLOO, J, VOJTEKOVA, K, VAN ZANTWIJK, C. H, ZWEEGMAN, S, CHAN, E. T, KIRK, C. J, GEERKE, D. P
Published in Leukemia (01.04.2012)
Published in Leukemia (01.04.2012)
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Journal Article
Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma
MAO, X, LI, X, ROSE, D, BATEY, R. A, KAY, L. E, SCHIMMER, A. D, SPRANGERS, R, WANG, X, VENUGOPAL, A, WOOD, T, ZHANG, Y, KUNTZ, D. A, COE, E, TRUDEL, S
Published in Leukemia (01.03.2009)
Published in Leukemia (01.03.2009)
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Inhibition of intracellular dipeptidyl peptidases 8 and 9 enhances parthenolide's anti-leukemic activity
Spagnuolo, P A, Hurren, R, Gronda, M, MacLean, N, Datti, A, Basheer, A, Lin, F-H, Wang, X, Wrana, J, Schimmer, A D
Published in Leukemia (01.06.2013)
Published in Leukemia (01.06.2013)
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Journal Article
Targeting XIAP for the treatment of malignancy
Schimmer, A D, Dalili, S, Batey, R A, Riedl, S J
Published in Cell death and differentiation (01.02.2006)
Published in Cell death and differentiation (01.02.2006)
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Journal Article
New model systems provide insights into Myc-induced transformation
WASYLISHEN, A. R, STOJANOVA, A, OLIVERI, S, RUST, A. C, SCHIMMER, A. D, PENN, L. Z
Published in Oncogene (25.08.2011)
Published in Oncogene (25.08.2011)
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A phase I II study of imatinib plus reinduction therapy for c-kit-positive relapsed refractory acute myeloid leukemia: inhibition of Akt activation correlates with complete response
BRANDWEIN, J. M, HEDLEY, D. W, CHOW, S, SCHIMMER, A. D, YEE, K. W. L, SCHUH, A. C, GUPTA, V, XU, W, KAMEL-REID, S, MINDEN, M. D
Published in Leukemia (01.06.2011)
Published in Leukemia (01.06.2011)
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Journal Article
Biological and clinical consequences of NPM1 mutations in AML
Heath, E M, Chan, S M, Minden, M D, Murphy, T, Shlush, L I, Schimmer, A D
Published in Leukemia (01.04.2017)
Published in Leukemia (01.04.2017)
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Journal Article
Synthetic triterpenoids activate a pathway for apoptosis in AML cells involving downregulation of FLIP and sensitization to TRAIL
SUH, W-S, KIM, Y. S, SCHIMMER, A. D, KITADA, S, MINDEN, M, ANDREEFF, M, SUH, N, SPORN, M, REED, J. C
Published in Leukemia (01.11.2003)
Published in Leukemia (01.11.2003)
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The repositioning of the anti-fungal agent ciclopirox olamine as a novel therapeutic agent for the treatment of haematologic malignancy
Weir, S. J., Patton, L., Castle, K., Rajewski, L., Kasper, J., Schimmer, A. D.
Published in Journal of clinical pharmacy and therapeutics (01.04.2011)
Published in Journal of clinical pharmacy and therapeutics (01.04.2011)
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Journal Article
A phase I study of tipifarnib combined with conventional induction and consolidation therapy for previously untreated patients with acute myeloid leukemia aged 60 years and over
BRANDWEIN, J. M, LEBER, B. F, MINDEN, M. D, HOWSON-JAN, K, SCHIMMER, A. D, SCHUH, A. C, GUPTA, V, YEE, K. W. L, WRIGHT, J, MOORE, M, MACALPINE, K
Published in Leukemia (01.04.2009)
Published in Leukemia (01.04.2009)
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Journal Article
Impaired bortezomib binding to mutant beta 5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells
Franke, N E, Niewerth, D, Assaraf, Y G, van Meerloo, J, Vojtekova, K, van Zantwijk, C H, Zweegman, S, Chan, E T, Kirk, C J, Geerke, D P, Schimmer, A D, Kaspers, G J L, Jansen, G, Cloos, J
Published in Leukemia (01.04.2012)
Published in Leukemia (01.04.2012)
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Journal Article
Decreased bone mineral density is common after autologous blood or marrow transplantation
SCHIMMER, A. D, MAH, K, BORDELEAU, L, CHEUNG, A, ALI, V, FALCONER, M, TRUS, M, KEATING, A
Published in Bone marrow transplantation (Basingstoke) (01.08.2001)
Published in Bone marrow transplantation (Basingstoke) (01.08.2001)
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Journal Article
Allogeneic or autologous bone marrow transplantation (BMT) for non-Hodgkin's lymphoma (NHL): results of a provincial strategy
SCHIMMER, A. D, JAMAL, S, MESSNER, H, KEATING, A, MEHARCHAND, J, HUEBSCH, L, WALKER, I, BENGER, A, GLUCK, S, SMITH, A
Published in Bone marrow transplantation (Basingstoke) (01.10.2000)
Published in Bone marrow transplantation (Basingstoke) (01.10.2000)
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Journal Article
Ovarian function after autologous bone marrow transplantation
Schimmer, A D, Quatermain, M, Imrie, K, Ali, V, McCrae, J, Stewart, A K, Crump, M, Derzko, C, Keating, A
Published in Journal of clinical oncology (01.07.1998)
Published in Journal of clinical oncology (01.07.1998)
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Effect of an antimicrobial stewardship programme on antimicrobial utilisation and costs in patients with leukaemia: a retrospective controlled study
So, M., Mamdani, M.M., Morris, A.M., Lau, T.T.Y., Broady, R., Deotare, U., Grant, J., Kim, D., Schimmer, A.D., Schuh, A.C., Shajari, S., Steinberg, M., Bell, C.M., Husain, S.
Published in Clinical microbiology and infection (01.08.2018)
Published in Clinical microbiology and infection (01.08.2018)
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Journal Article
Higher ratio immune versus constitutive proteasome level as novel indicator of sensitivity of pediatric acute leukemia cells to proteasome inhibitors
Niewerth, Denise, Franke, Niels E, Jansen, Gerrit, Assaraf, Yehuda G, van Meerloo, Johan, Kirk, Christopher J, Degenhardt, Jeremiah, Anderl, Janet, Schimmer, Aaron D, Zweegman, Sonja, de Haas, Valerie, Horton, Terzah M, Kaspers, Gertjan J L, Cloos, Jacqueline
Published in Haematologica (Roma) (01.12.2013)
Published in Haematologica (Roma) (01.12.2013)
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Journal Article
Expression of CD4 is correlated with an unfavorable prognosis in wild‐type NPM1, FLT3‐ITD‐negative cytogenetically normal adult acute myeloid leukemia
Guo, R. J., Atenafu, E. G., Schimmer, A. D., Minden, M. D., Chang, H.
Published in International journal of laboratory hematology (01.08.2017)
Published in International journal of laboratory hematology (01.08.2017)
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Journal Article
Busulfan and cyclophosphamide as a preparative regimen for allogeneic blood and marrow transplantation in patients with non-Hodgkin's lymphoma
KISS, T. L, PANZARELLA, T, MESSNER, H. A, MEHARCHAND, J, REDDY, V, SCHIMMER, A. D, LIPTON, J. H
Published in Bone marrow transplantation (Basingstoke) (02.01.2003)
Published in Bone marrow transplantation (Basingstoke) (02.01.2003)
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