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Published in Cancer discovery (01.05.2021)
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The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair
Shafi, Ayesha A., McNair, Chris M., McCann, Jennifer J., Alshalalfa, Mohammed, Shostak, Anton, Severson, Tesa M., Zhu, Yanyun, Bergman, Andre, Gordon, Nicolas, Mandigo, Amy C., Chand, Saswati N., Gallagher, Peter, Dylgjeri, Emanuela, Laufer, Talya S., Vasilevskaya, Irina A., Schiewer, Matthew J., Brunner, Michael, Feng, Felix Y., Zwart, Wilbert, Knudsen, Karen E.
Published in Nature communications (15.01.2021)
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A hormone-DNA repair circuit governs the response to genotoxic insult
Goodwin, Jonathan F, Schiewer, Matthew J, Dean, Jeffry L, Schrecengost, Randy S, de Leeuw, Renée, Han, Sumin, Ma, Teng, Den, Robert B, Dicker, Adam P, Feng, Felix Y, Knudsen, Karen E
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MAPK Reliance via Acquired CDK4/6 Inhibitor Resistance in Cancer
de Leeuw, Renée, McNair, Christopher, Schiewer, Matthew J, Neupane, Neermala Poudel, Brand, Lucas J, Augello, Michael A, Li, Zhen, Cheng, Larry C, Yoshida, Akihiro, Courtney, Sean M, Hazard, E Starr, Hardiman, Gary, Hussain, Maha H, Diehl, J Alan, Drake, Justin M, Kelly, Wm Kevin, Knudsen, Karen E
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DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis
Goodwin, Jonathan F., Kothari, Vishal, Drake, Justin M., Zhao, Shuang, Dylgjeri, Emanuela, Dean, Jeffry L., Schiewer, Matthew J., McNair, Christopher, Jones, Jennifer K., Aytes, Alvaro, Magee, Michael S., Snook, Adam E., Zhu, Ziqi, Den, Robert B., Birbe, Ruth C., Gomella, Leonard G., Graham, Nicholas A., Vashisht, Ajay A., Wohlschlegel, James A., Graeber, Thomas G., Karnes, R. Jeffrey, Takhar, Mandeep, Davicioni, Elai, Tomlins, Scott A., Abate-Shen, Cory, Sharifi, Nima, Witte, Owen N., Feng, Felix Y., Knudsen, Karen E.
Published in Cancer cell (13.07.2015)
Published in Cancer cell (13.07.2015)
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USP22 Functions as an Oncogenic Driver in Prostate Cancer by Regulating Cell Proliferation and DNA Repair
McCann, Jennifer J, Vasilevskaya, Irina A, Poudel Neupane, Neermala, Shafi, Ayesha A, McNair, Christopher, Dylgjeri, Emanuela, Mandigo, Amy C, Schiewer, Matthew J, Schrecengost, Randy S, Gallagher, Peter, Stanek, Timothy J, McMahon, Steven B, Berman-Booty, Lisa D, Ostrander, Jr, William F, Knudsen, Karen E
Published in Cancer research (Chicago, Ill.) (01.02.2020)
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RB/E2F1 as a Master Regulator of Cancer Cell Metabolism in Advanced Disease
Mandigo, Amy C, Yuan, Wei, Xu, Kexin, Gallagher, Peter, Pang, Angel, Guan, Yi Fang, Shafi, Ayesha A, Thangavel, Chellappagounder, Sheehan, Beshara, Bogdan, Denisa, Paschalis, Alec, McCann, Jennifer J, Laufer, Talya S, Gordon, Nicolas, Vasilevskaya, Irina A, Dylgjeri, Emanuela, Chand, Saswati N, Schiewer, Matthew J, Domingo-Domenech, Josep, Den, Robert B, Holst, Jeff, McCue, Peter A, de Bono, Johann S, McNair, Christopher, Knudsen, Karen E
Published in Cancer discovery (01.09.2021)
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Novel actions of next-generation taxanes benefit advanced stages of prostate cancer
de Leeuw, Renée, Berman-Booty, Lisa D, Schiewer, Matthew J, Ciment, Stephen J, Den, Robert B, Dicker, Adam P, Kelly, William K, Trabulsi, Edouard J, Lallas, Costas D, Gomella, Leonard G, Knudsen, Karen E
Published in Clinical cancer research (15.02.2015)
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Dual roles of PARP-1 promote cancer growth and progression
Schiewer, Matthew J, Goodwin, Jonathan F, Han, Sumin, Brenner, J Chad, Augello, Michael A, Dean, Jeffry L, Liu, Fengzhi, Planck, Jamie L, Ravindranathan, Preethi, Chinnaiyan, Arul M, McCue, Peter, Gomella, Leonard G, Raj, Ganesh V, Dicker, Adam P, Brody, Jonathan R, Pascal, John M, Centenera, Margaret M, Butler, Lisa M, Tilley, Wayne D, Feng, Felix Y, Knudsen, Karen E
Published in Cancer discovery (01.12.2012)
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Mutant p53 elicits context-dependent pro-tumorigenic phenotypes
McCann, Jennifer J., Vasilevskaya, Irina A., McNair, Christopher, Gallagher, Peter, Neupane, Neermala Poudel, de Leeuw, Renée, Shafi, Ayesha A., Dylgjeri, Emanuela, Mandigo, Amy C., Schiewer, Matthew J., Knudsen, Karen E.
Published in Oncogene (12.01.2022)
Published in Oncogene (12.01.2022)
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A patient‐derived explant (PDE) model of hormone‐dependent cancer
Centenera, Margaret M., Hickey, Theresa E., Jindal, Shalini, Ryan, Natalie K., Ravindranathan, Preethi, Mohammed, Hisham, Robinson, Jessica L., Schiewer, Matthew J., Ma, Shihong, Kapur, Payal, Sutherland, Peter D., Hoffmann, Clive E., Roehrborn, Claus G., Gomella, Leonard G., Carroll, Jason S., Birrell, Stephen N., Knudsen, Karen E., Raj, Ganesh V., Butler, Lisa M., Tilley, Wayne D.
Published in Molecular oncology (01.09.2018)
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Posttranscriptional Regulation of PARG mRNA by HuR Facilitates DNA Repair and Resistance to PARP Inhibitors
Chand, Saswati N, Zarei, Mahsa, Schiewer, Matthew J, Kamath, Akshay R, Romeo, Carmella, Lal, Shruti, Cozzitorto, Joseph A, Nevler, Avinoam, Scolaro, Laura, Londin, Eric, Jiang, Wei, Meisner-Kober, Nicole, Pishvaian, Michael J, Knudsen, Karen E, Yeo, Charles J, Pascal, John M, Winter, Jordan M, Brody, Jonathan R
Published in Cancer research (Chicago, Ill.) (15.09.2017)
Published in Cancer research (Chicago, Ill.) (15.09.2017)
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USP22 Regulates Oncogenic Signaling Pathways to Drive Lethal Cancer Progression
SCHRECENGOST, Randy S, DEAN, Jeffry L, VISAKORPI, Tapio, DEMARZO, Angelo M, MCMAHON, Steven B, KNUDSEN, Karen E, GOODWIN, Jonathan F, SCHIEWER, Matthew J, URBAN, Mark W, STANEK, Timothy J, SUSSMAN, Robyn T, HICKS, Jessica L, BIRBE, Ruth C, DRAGANOVA-TACHEVA, Rossitza A
Published in Cancer research (Chicago, Ill.) (01.01.2014)
Published in Cancer research (Chicago, Ill.) (01.01.2014)
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PARP‐1 regulates DNA repair factor availability
Schiewer, Matthew J, Mandigo, Amy C, Gordon, Nicolas, Huang, Fangjin, Gaur, Sanchaika, de Leeuw, Renée, Zhao, Shuang G, Evans, Joseph, Han, Sumin, Parsons, Theodore, Birbe, Ruth, McCue, Peter, McNair, Christopher, Chand, Saswati N, Cendon‐Florez, Ylenia, Gallagher, Peter, McCann, Jennifer J, Poudel Neupane, Neermala, Shafi, Ayesha A, Dylgjeri, Emanuela, Brand, Lucas J, Visakorpi, Tapio, Raj, Ganesh V, Lallas, Costas D, Trabulsi, Edouard J, Gomella, Leonard G, Dicker, Adam P, Kelly, Wm. Kevin, Leiby, Benjamin E, Knudsen, Beatrice, Feng, Felix Y, Knudsen, Karen E
Published in EMBO molecular medicine (01.12.2018)
Published in EMBO molecular medicine (01.12.2018)
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Identification of ASF/SF2 as a Critical, Allele-Specific Effector of the Cyclin D1b Oncogene
OLSHAVSKI, Nicholas A, COMSTOCK, Clay E. S, CHIEWE, Matthew J. S, AUGELLO, Michael A, HYSIOP, Terry, SETTE, Claudio, JINSONG ZHANG, PARYSEK, Linda M, KNUDSEN, Karen E
Published in Cancer research (Chicago, Ill.) (15.05.2010)
Published in Cancer research (Chicago, Ill.) (15.05.2010)
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mTOR is a selective effector of the radiation therapy response in androgen receptor-positive prostate cancer
Schiewer, Matthew J, Den, Robert, Hoang, David T, Augello, Michael A, Lawrence, Yaacov R, Dicker, Adam P, Knudsen, Karen E
Published in Endocrine-related cancer (01.02.2012)
Published in Endocrine-related cancer (01.02.2012)
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Consequence of the tumor‐associated conversion to cyclin D1b
Augello, Michael A, Berman‐Booty, Lisa D, Carr, Richard, Yoshida, Akihiro, Dean, Jeffry L, Schiewer, Matthew J, Feng, Felix Y, Tomlins, Scott A, Gao, Erhe, Koch, Walter J, Benovic, Jeffrey L, Diehl, John Alan, Knudsen, Karen E
Published in EMBO molecular medicine (01.05.2015)
Published in EMBO molecular medicine (01.05.2015)
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