Potent peptidic fusion inhibitors of influenza virus
Kadam, Rameshwar U., Juraszek, Jarek, Brandenburg, Boerries, Buyck, Christophe, Schepens, Wim B. G., Kesteleyn, Bart, Stoops, Bart, Vreeken, Rob J., Vermond, Jan, Goutier, Wouter, Tang, Chan, Vogels, Ronald, Friesen, Robert H. E., Goudsmit, Jaap, van Dongen, Maria J. P., Wilson, Ian A.
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Published in Science (American Association for the Advancement of Science) (27.10.2017)
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A small-molecule fusion inhibitor of influenza virus is orally active in mice
van Dongen, Maria J P, Kadam, Rameshwar U, Juraszek, Jarek, Lawson, Edward, Brandenburg, Boerries, Schmitz, Frederike, Schepens, Wim B G, Stoops, Bart, van Diepen, Harry A, Jongeneelen, Mandy, Tang, Chan, Vermond, Jan, van Eijgen-Obregoso Real, Alida, Blokland, Sven, Garg, Divita, Yu, Wenli, Goutier, Wouter, Lanckacker, Ellen, Klap, Jaco M, Peeters, Daniëlle C G, Wu, Jin, Buyck, Christophe, Jonckers, Tim H M, Roymans, Dirk, Roevens, Peter, Vogels, Ronald, Koudstaal, Wouter, Friesen, Robert H E, Raboisson, Pierre, Dhanak, Dashyant, Goudsmit, Jaap, Wilson, Ian A
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Published in Science (American Association for the Advancement of Science) (08.03.2019)
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The First One-Pot Synthesis of l‑7-Iodotryptophan from 7‑Iodoindole and Serine, and an Improved Synthesis of Other l‑7-Halotryptophans
Smith, Duncan R. M, Willemse, Tom, Gkotsi, Danai S, Schepens, Wim, Maes, Bert U. W, Ballet, Steven, Goss, Rebecca J. M
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Published in Organic letters (16.05.2014)
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The Suzuki–Miyaura Cross-Coupling as a Versatile Tool for Peptide Diversification and Cyclization
Willemse, Tom, Schepens, Wim, Vlijmen, Herman, Maes, Bert, Ballet, Steven
Published in Catalysts (01.03.2017)
Published in Catalysts (01.03.2017)
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Design and synthesis of HIV-1 protease inhibitors for a long-acting injectable drug application
Kesteleyn, Bart, Amssoms, Katie, Schepens, Wim, Hache, Geerwin, Verschueren, Wim, Van De Vreken, Wim, Rombauts, Klara, Meurs, Greet, Sterkens, Patrick, Stoops, Bart, Baert, Lieven, Austin, Nigel, Wegner, Jörg, Masungi, Chantal, Dierynck, Inge, Lundgren, Stina, Jönsson, Daniel, Parkes, Kevin, Kalayanov, Genadiy, Wallberg, Hans, Rosenquist, Åsa, Samuelsson, Bertil, Van Emelen, Kristof, Thuring, Jan Willem
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Discovery and Pharmacological Characterization of JNJ-64619178, a Novel Small-Molecule Inhibitor of PRMT5 with Potent Antitumor Activity
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Published in Molecular cancer therapeutics (01.12.2021)
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Abstract 5567A: JNJ-‘6196: A next generation STING agonist with potent preclinical activity by the IV route
Chan, Szeman Ruby, Bignan, Gilles, Pierson, Emily, Mahady, Sally, Ta, Hayley, Schepens, Wim, Thuring, Jan Willem, Lim, Heng Keang, Otieno, Monicah, Wilde, Thomas, Singer, Monica, Bogdan, Nancy, Patel, Shefali, Luistro, Leo, Campion, Liam, Smith, Melissa, Wiley, Diana, Packman, Kathryn, Allegrezza, Michael, Morgan, Caitlin, Sendecki, Jocelyn, Van Aller, Glenn, Krosky, Daniel, Connolly, Peter, Edwards, James, Staquet, Kim, Emanuel, Stuart L.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Chemical space screening around Phe(3) in opioid peptides: Modulating mu versus delta agonism by Suzuki-Miyaura cross-couplings
Willemse, Tom, Eiselt, Emilie, Hollanders, Karlijn, Schepens, Wim, van Vlijmen, Herman W. T., Chung, Nga N., Blais, Veronique, Holleran, Brain, Longpre, Jean-Michel, Schiller, Peter W., Maes, Bert U. W., Sarret, Philippe, Gendron, Louis, Ballet, Steven
Published in Bioorganic & medicinal chemistry letters (15.07.2018)
Published in Bioorganic & medicinal chemistry letters (15.07.2018)
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An orally active small molecule fusion inhibitor of influenza virus
van Dongen, Maria J.P., Kadam, Rameshwar U., Juraszek, Jarek, Lawson, Edward, Brandenburg, Boerries, Schmitz, Frederike, Schepens, Wim B.G., Stoops, Bart, van Diepen, Harry A., Jongeneelen, Mandy, Tang, Chan, Vermond, Jan, Real, Alida van Eijgen-Obregoso, Blokland, Sven, Garg, Divita, Wu, Wenli, Goutier, Wouter, Lanckacker, Ellen, Klap, Jaco M., Peeters, Daniëlle C. G., Wu, Jin, Buyck, Christophe, Jonckers, Tim H. M., Roymans, Dirk, Roevens, Peter, Vogels, Ronald, Koudstaal, Wouter, Friesen, Robert H. E., Raboisson, Pierre, Dhanak, Dashyant, Goudsmit, Jaap, Wilson, Ian A.
Published in Science (American Association for the Advancement of Science) (08.03.2019)
Published in Science (American Association for the Advancement of Science) (08.03.2019)
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Suzuki-Miyaura Diversification of Amino Acids and Dipeptides in Aqueous Media
Willemse, Tom, Van Imp, Karolien, Goss, Rebecca J. M., Van Vlijmen, Herman W. T., Schepens, Wim, Maes, Bert U. W., Ballet, Steven
Published in ChemCatChem (13.07.2015)
Published in ChemCatChem (13.07.2015)
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Corrigendum to “Chemical space screening around Phe3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings” [Bioorg. Med. Chem. Lett. 28(13) (2018) 2320–2323]
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Published in Bioorganic & medicinal chemistry letters (01.11.2018)
Published in Bioorganic & medicinal chemistry letters (01.11.2018)
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Chemical space screening around Phe3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings
Willemse, Tom, Eiselt, Emilie, Hollanders, Karlijn, Schepens, Wim, van Vlijmen, Herman W.T., Chung, Nga N., Blais, Véronique, Holleran, Brain, Longpré, Jean-Michel, Schiller, Peter W., Maes, Bert U.W., Sarret, Philippe, Gendron, Louis, Ballet, Steven
Published in Bioorganic & medicinal chemistry letters (15.07.2018)
Published in Bioorganic & medicinal chemistry letters (15.07.2018)
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Benzoxazole and benzothiazole amides as novel pharmacokinetic enhancers of HIV protease inhibitors
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Published in Bioorganic & medicinal chemistry letters (01.08.2012)
Published in Bioorganic & medicinal chemistry letters (01.08.2012)
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Year of Publication 06.02.2024
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Year of Publication 06.02.2024
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Abstract DDT02-04: A novel PRMT5 inhibitor with potent in vitro and in vivo activity in preclinical lung cancer models
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Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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STING 효능제로서의 사이클릭 다이뉴클레오티드
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Year of Publication 25.03.2021
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Year of Publication 25.03.2021
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Inside Back Cover: Suzuki-Miyaura Diversification of Amino Acids and Dipeptides in Aqueous Media (ChemCatChem 14/2015)
Willemse, Tom, Van Imp, Karolien, Goss, Rebecca J. M., Van Vlijmen, Herman W. T., Schepens, Wim, Maes, Bert U. W., Ballet, Steven
Published in ChemCatChem (13.07.2015)
Published in ChemCatChem (13.07.2015)
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STING 작용제로서의 환상 다이뉴클레오티드
EDWARDS JAMES PATRICK, THATIKONDA SANTHOSH KUMAR, LAQUERRE SYLVIA, EMANUEL STUART, VIELLEVOYE MARCEL, WANG GUANGYI, SCHEPENS WIM GERT GRIET, THURING JOHANNES WILHELMUS JOHN FITZGERALD, ZHONG MINGHONG, RICHTER MARK, BEIGELMAN LEONID, BIGNAN GILLES, CONNOLLY PETER J
Year of Publication 21.08.2020
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Year of Publication 21.08.2020
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Corrigendum to "Chemical space screening around Phe 3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings" [Bioorg. Med. Chem. Lett. 28(13) (2018) 2320-2323]
Willemse, Tom, Eiselt, Emilie, Hollanders, Karlijn, Schepens, Wim, van Vlijmen, Herman W T, Chung, Nga N, Blais, Véronique, Holleran, Brian, Longpré, Jean-Michel, Schiller, Peter W, Maes, Bert U W, Sarret, Philippe, Gendron, Louis, Ballet, Steven
Published in Bioorganic & medicinal chemistry letters (01.11.2018)
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Published in Bioorganic & medicinal chemistry letters (01.11.2018)
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Chemical space screening around Phe 3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings
Willemse, Tom, Eiselt, Emilie, Hollanders, Karlijn, Schepens, Wim, van Vlijmen, Herman W T, Chung, Nga N, Blais, Véronique, Holleran, Brain, Longpré, Jean-Michel, Schiller, Peter W, Maes, Bert U W, Sarret, Philippe, Gendron, Louis, Ballet, Steven
Published in Bioorganic & medicinal chemistry letters (15.07.2018)
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Published in Bioorganic & medicinal chemistry letters (15.07.2018)
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