Removal of BFL-1 sensitises some melanoma cells to killing by BH3 mimetic drugs
Gangoda, Lahiru, Schenk, Robyn L, Tai, Lin, Szeto, Pacman, Cheung, Jen G, Strasser, Andreas, Lessene, Guillaume, Shackleton, Mark, Herold, Marco J
Published in Cell death & disease (04.04.2022)
Published in Cell death & disease (04.04.2022)
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Journal Article
Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite’s chloroquine resistance transporter
Summers, Robert L, Dave, Anurag, Dolstra, Tegan J, Bellanca, Sebastiano, Marchetti, Rosa V, Nash, Megan N, Richards, Sashika N, Goh, Valerie, Schenk, Robyn L, Stein, Wilfred D, Kirk, Kiaran, Sanchez, Cecilia P, Lanzer, Michael, Martin, Rowena E
Published in Proceedings of the National Academy of Sciences - PNAS (29.04.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (29.04.2014)
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Journal Article
GM-CSF Quantity Has a Selective Effect on Granulocytic vs. Monocytic Myeloid Development and Function
Sun, Li, Rautela, Jai, Delconte, Rebecca B, Souza-Fonseca-Guimaraes, Fernando, Carrington, Emma M, Schenk, Robyn L, Herold, Marco J, Huntington, Nicholas D, Lew, Andrew M, Xu, Yuekang, Zhan, Yifan
Published in Frontiers in immunology (28.08.2018)
Published in Frontiers in immunology (28.08.2018)
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Journal Article
DNA repair processes are critical mediators of p53-dependent tumor suppression
Janic, Ana, Valente, Liz J, Wakefield, Matthew J, Di Stefano, Leon, Milla, Liz, Wilcox, Stephen, Yang, Haoyu, Tai, Lin, Vandenberg, Cassandra J, Kueh, Andrew J, Mizutani, Shinsuke, Brennan, Margs S, Schenk, Robyn L, Lindqvist, Lisa M, Papenfuss, Anthony T, O'Connor, Liam, Strasser, Andreas, Herold, Marco J
Published in Nature medicine (01.07.2018)
Published in Nature medicine (01.07.2018)
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Journal Article
Transcriptional function of E2A, Ebf1, Pax5, Ikaros and Aiolos analyzed by in vivo acute protein degradation in early B cell development
Fedl, Anna S, Tagoh, Hiromi, Gruenbacher, Sarah, Sun, Qiong, Schenk, Robyn L, Froussios, Kimon, Jaritz, Markus, Busslinger, Meinrad, Schwickert, Tanja A
Published in Nature immunology (01.09.2024)
Published in Nature immunology (01.09.2024)
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Journal Article
Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo
Carrington, Emma M, Zhan, Yifan, Brady, Jamie L, Zhang, Jian-Guo, Sutherland, Robyn M, Anstee, Natasha S, Schenk, Robyn L, Vikstrom, Ingela B, Delconte, Rebecca B, Segal, David, Huntington, Nicholas D, Bouillet, Philippe, Tarlinton, David M, Huang, David Cs, Strasser, Andreas, Cory, Suzanne, Herold, Marco J, Lew, Andrew M
Published in Cell death and differentiation (01.05.2017)
Published in Cell death and differentiation (01.05.2017)
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Journal Article
Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment
Schenk, Robyn L, Tuzlak, Selma, Carrington, Emma M, Zhan, Yifan, Heinzel, Susanne, Teh, Charis E, Gray, Daniel H, Tai, Lin, Lew, Andrew M, Villunger, Andreas, Strasser, Andreas, Herold, Marco J
Published in Cell death and differentiation (01.03.2017)
Published in Cell death and differentiation (01.03.2017)
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Journal Article
Absence of pro-survival A1 has no impact on inflammatory cell survival in vivo during acute lung inflammation and peritonitis
Gangoda, Lahiru, Schenk, Robyn L, Best, Sarah A, Nedeva, Christina, Louis, Cynthia, D'Silva, Damian B, Fairfax, Kirsten, Jarnicki, Andrew G, Puthalakath, Hamsa, Sutherland, Kate D, Strasser, Andreas, Herold, Marco J
Published in Cell death and differentiation (01.01.2022)
Published in Cell death and differentiation (01.01.2022)
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Journal Article
The BCL-2 pro-survival protein A1 is dispensable for T cell homeostasis on viral infection
Tuzlak, Selma, Schenk, Robyn L, Vasanthakumar, Ajithkumar, Preston, Simon P, Haschka, Manuel D, Zotos, Dimitra, Kallies, Axel, Strasser, Andreas, Villunger, Andreas, Herold, Marco J
Published in Cell death and differentiation (01.03.2017)
Published in Cell death and differentiation (01.03.2017)
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Journal Article
The pro-survival Bcl-2 family member A1 delays spontaneous and FAS ligand-induced apoptosis of activated neutrophils
Schenk, Robyn L, Gangoda, Lahiru, Lawlor, Kate E, O'Reilly, Lorraine A, Strasser, Andreas, Herold, Marco J
Published in Cell death & disease (18.06.2020)
Published in Cell death & disease (18.06.2020)
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Journal Article
BCL-2: Long and winding path from discovery to therapeutic target
Schenk, Robyn L., Strasser, Andreas, Dewson, Grant
Published in Biochemical and biophysical research communications (15.01.2017)
Published in Biochemical and biophysical research communications (15.01.2017)
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Journal Article
Anti-apoptotic A1 is not essential for lymphoma development in Eµ-Myc mice but helps sustain transplanted Eµ-Myc tumour cells
Mensink, Mark, Anstee, Natasha S, Robati, Mikara, Schenk, Robyn L, Herold, Marco J, Cory, Suzanne, Vandenberg, Cassandra J
Published in Cell death and differentiation (01.03.2018)
Published in Cell death and differentiation (01.03.2018)
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Journal Article
BCL-XL antagonism selectively reduces neutrophil life span within inflamed tissues without causing neutropenia
Carrington, Emma M., Louis, Cynthia, Kratina, Tobias, Hancock, Manuela, Keenan, Christine R., Iannarella, Nadia, Allan, Rhys S., Wardak, Ahmad Z., Czabotar, Peter E., Herold, Marco J., Schenk, Robyn L., White, Christine A., D'Silva, Damian, Yang, Yuyan, Wong, Wesley, Wong, Huon, Bryant, Vanessa L., Huntington, Nicholas D., Rautela, Jai, Sutherland, Robyn M., Zhan, Yifan, Hansen, Jacinta, Nhu, Duong, Lessene, Guillaume, Wicks, Ian P., Lew, Andrew M.
Published in Blood advances (08.06.2021)
Published in Blood advances (08.06.2021)
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Journal Article
Abstract 2080: SOS1 inhibition is an effective therapeutic strategy in SOS1-mutant cancer
Sale, Matthew J., Mukherjee, Neal, Koch, Martín, Ruzicka, Regina, Jacob, Robin, Albrecht, Christoph, Zanin, Teresa, Madensky, Thomas, Schenk, Robyn L., Baum, Anke, Kostyrko, Kaja, Gerlach, Daniel, Hofmann, Marco H., McCormick, Frank
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract 1715: SOS1 inhibition is an effective therapeutic strategy in SOS1-mutant cancer
Sale, Matthew J., Mukherjee, Neal, Ruzicka, Regina, Jacob, Robin, Albrecht, Christoph, Zanin, Teresa, Madensky, Tom, Kostyrko, Kaja, Schenk, Robyn L., Baum, Anke, Gerlach, Daniel, Hofmann, Marco H., McCormick, Frank
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract 6506: SOS1 inhibition in combination with HER2 inhibition in models of HER2-driven cancer
Schenk, Robyn L., Kostyrko, Kaja, Popow, Johannes, Gewinner, Christina, Baum, Anke, Albrecht, Christoph, Hinkel, Melanie, Jacob, Robin, Madensky, Tom, Ruzicka, Regina, Strauss, Eva, Lyu, Hengyu, Lopez, Anastasia M., Feng, Ningping, Vellano, Christopher P., Marszalek, Joseph R., Heffernan, Timothy P., Pearson, Mark, Hofmann, Marco H.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite's chloroquine resistance transporter
Summers, Robert L., Dave, Anurage, Dolstra, Tegan J., Bellanca, Sebastiano, Marchetti, Rosa V., Nash, Megan N., Richards, Sashika N., Goh, Valerie, Schenk, Robyn L., Stein, Wilfred D., Kirk, Kiaran, Sanchez, Cecilia P., Lanzer, Michael, Martin, Rowena E.
Published in Proceedings of the National Academy of Sciences - PNAS (29.04.2014)
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Published in Proceedings of the National Academy of Sciences - PNAS (29.04.2014)
Journal Article