Practical Guidelines for Therapeutic Drug Monitoring of Anticancer Tyrosine Kinase Inhibitors: Focus on the Pharmacokinetic Targets
Yu, Huixin, Steeghs, Neeltje, Nijenhuis, Cynthia M., Schellens, Jan H. M., Beijnen, Jos H., Huitema, Alwin D. R.
Published in Clinical pharmacokinetics (01.04.2014)
Published in Clinical pharmacokinetics (01.04.2014)
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Journal Article
Photodynamic Therapy in Oncology
Triesscheijn, Martijn, Baas, Paul, Schellens, Jan H. M., Stewart, Fiona A.
Published in The oncologist (Dayton, Ohio) (01.10.2006)
Published in The oncologist (Dayton, Ohio) (01.10.2006)
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Journal Article
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
Fong, Peter C, Boss, David S, Yap, Timothy A, Tutt, Andrew, Wu, Peijun, Mergui-Roelvink, Marja, Mortimer, Peter, Swaisland, Helen, Lau, Alan, O'Connor, Mark J, Ashworth, Alan, Carmichael, James, Kaye, Stan B, Schellens, Jan H.M, de Bono, Johann S
Published in The New England journal of medicine (09.07.2009)
Published in The New England journal of medicine (09.07.2009)
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Journal Article
Oral Anticancer Drugs: Mechanisms of Low Bioavailability and Strategies for Improvement
Stuurman, Frederik E., Nuijen, Bastiaan, Beijnen, Jos H., Schellens, Jan H. M.
Published in Clinical pharmacokinetics (01.06.2013)
Published in Clinical pharmacokinetics (01.06.2013)
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Journal Article
Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies
Keizer, Ron J., Huitema, Alwin D. R., Schellens, Jan H. M., Beijnen, Jos H.
Published in Clinical pharmacokinetics (01.08.2010)
Published in Clinical pharmacokinetics (01.08.2010)
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Journal Article
A Phase I and Pharmacological Study with Imidazolium-trans-DMSO-imidazole-tetrachlororuthenate, a Novel Ruthenium Anticancer Agent
RADEMAKER-LAKHAI, Jeany M, VAN DEN BONGARD, Desiree, PLUIM, Dick, BEIJNEN, Jos H, SCHELLENS, Jan H. M
Published in Clinical cancer research (01.06.2004)
Published in Clinical cancer research (01.06.2004)
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Journal Article
Restricted brain penetration of the tyrosine kinase inhibitor erlotinib due to the drug transporters P-gp and BCRP
de Vries, Nienke A., Buckle, Tessa, Zhao, Jin, Beijnen, Jos H., Schellens, Jan H. M., van Tellingen, Olaf
Published in Investigational new drugs (01.04.2012)
Published in Investigational new drugs (01.04.2012)
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Journal Article
Relationship between Single Nucleotide Polymorphisms and Haplotypes in DPYD and Toxicity and Efficacy of Capecitabine in Advanced Colorectal Cancer
DEENEN, Maarten J, TOL, Jolien, SCHELLENS, Jan H. M, CATS, Annemieke, BURYLO, Artur M, DOODEMAN, Valerie D, DE BOER, Anthonius, VINCENT, Andrew, GUCHELAAR, Henk-Jan, SMITS, Paul H. M, BEIJNEN, Jos H, PUNT, Cornelis J. A
Published in Clinical cancer research (15.05.2011)
Published in Clinical cancer research (15.05.2011)
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Journal Article
Quantitative bioanalysis of peptides by liquid chromatography coupled to (tandem) mass spectrometry
van den Broek, Irene, Sparidans, Rolf W., Schellens, Jan H.M., Beijnen, Jos H.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.09.2008)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.09.2008)
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Journal Article
Electrospray Ionization Quadrupole Ion-Mobility Time-of-Flight Mass Spectrometry as a Tool to Distinguish the Lot-to-Lot Heterogeneity in N-Glycosylation Profile of the Therapeutic Monoclonal Antibody Trastuzumab
Damen, Carola W.N., Chen, Weibin, Chakraborty, Asish B., van Oosterhout, Mike, Mazzeo, Jeffrey R., Gebler, John C., Schellens, Jan H.M., Rosing, Hilde, Beijnen, Jos H.
Published in Journal of the American Society for Mass Spectrometry (01.11.2009)
Published in Journal of the American Society for Mass Spectrometry (01.11.2009)
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Journal Article
P‐glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel
Hendrikx, Jeroen J.M.A., Lagas, Jurjen S., Rosing, Hilde, Schellens, Jan H.M., Beijnen, Jos H., Schinkel, Alfred H.
Published in International journal of cancer (15.05.2013)
Published in International journal of cancer (15.05.2013)
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Journal Article
Clinical proteomics in breast cancer: a review
Gast, Marie-Christine W, Schellens, Jan H. M, Beijnen, Jos H
Published in Breast cancer research and treatment (01.07.2009)
Published in Breast cancer research and treatment (01.07.2009)
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Journal Article
The effect of P-gp (Mdr1a/1b), BCRP (Bcrp1) and P-gp/BCRP inhibitors on the in vivo absorption, distribution, metabolism and excretion of imatinib
Oostendorp, Roos L., Buckle, Tessa, Beijnen, Jos H., van Tellingen, Olaf, Schellens, Jan H. M.
Published in Investigational new drugs (01.02.2009)
Published in Investigational new drugs (01.02.2009)
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Journal Article
Quantitative assay for six potential breast cancer biomarker peptides in human serum by liquid chromatography coupled to tandem mass spectrometry
van den Broek, Irene, Sparidans, Rolf W., Schellens, Jan H.M., Beijnen, Jos H.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.02.2010)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.02.2010)
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Journal Article
Population pharmacokinetics of doxorubicin: establishment of a NONMEM model for adults and children older than 3 years
Kontny, Nina E., Würthwein, Gudrun, Joachim, Boos, Boddy, Alan V., Krischke, Miriam, Fuhr, Uwe, Thompson, Patrick A., Jörger, Markus, Schellens, Jan H. M., Hempel, Georg
Published in Cancer chemotherapy and pharmacology (01.03.2013)
Published in Cancer chemotherapy and pharmacology (01.03.2013)
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Journal Article
Phase I and pharmacokinetic trial of AP5346, a DACH-platinum-polymer conjugate, administered weekly for three out of every 4 weeks to advanced solid tumor patients
CAMPONE, Mario, RADEMAKER-LAKHAI, Jeany M, BENNOUNA, Jaafar, HOWELL, Stephen B, NOWOTNIK, David P, BEIJNEN, Jos H, SCHELLENS, Jan H. M
Published in Cancer chemotherapy and pharmacology (01.09.2007)
Published in Cancer chemotherapy and pharmacology (01.09.2007)
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Journal Article
Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy
Leijen, Suzanne, Burgers, Sjaak A., Baas, Paul, Pluim, Dick, Tibben, Matthijs, van Werkhoven, Erik, Alessio, Enzo, Sava, Gianni, Beijnen, Jos H., Schellens, Jan H. M.
Published in Investigational new drugs (01.02.2015)
Published in Investigational new drugs (01.02.2015)
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