ZATT (ZNF451)–mediated resolution of topoisomerase 2 DNA-protein cross-links
Schellenberg, Matthew J., Lieberman, Jenna Ariel, Herrero-Ruiz, Andrés, Butler, Logan R., Williams, Jason G., Muñoz-Cabello, Ana M., Mueller, Geoffrey A., London, Robert E., Cortés-Ledesma, Felipe, Williams, R. Scott
Published in Science (American Association for the Advancement of Science) (29.09.2017)
Published in Science (American Association for the Advancement of Science) (29.09.2017)
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Journal Article
Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease
Sharifi, Reza, Morra, Rosa, Denise Appel, C, Tallis, Michael, Chioza, Barry, Jankevicius, Gytis, Simpson, Michael A, Matic, Ivan, Ozkan, Ege, Golia, Barbara, Schellenberg, Matthew J, Weston, Ria, Williams, Jason G, Rossi, Marianna N, Galehdari, Hamid, Krahn, Juno, Wan, Alexander, Trembath, Richard C, Crosby, Andrew H, Ahel, Dragana, Hay, Ron, Ladurner, Andreas G, Timinszky, Gyula, Williams, R Scott, Ahel, Ivan
Published in The EMBO journal (02.05.2013)
Published in The EMBO journal (02.05.2013)
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Journal Article
ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes
Bunch, Heeyoun, Kim, Deukyeong, Naganuma, Masahiro, Nakagawa, Reiko, Cong, Anh, Jeong, Jaehyeon, Ehara, Haruhiko, Vu, Hongha, Chang, Jeong Ho, Schellenberg, Matthew J., Sekine, Shun-ichi
Published in Nature communications (14.12.2023)
Published in Nature communications (14.12.2023)
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Journal Article
Proteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2·DNA and Top2·RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2)
Gao, Rui, Schellenberg, Matthew J., Huang, Shar-yin N., Abdelmalak, Monica, Marchand, Christophe, Nitiss, Karin C., Nitiss, John L., Williams, R. Scott, Pommier, Yves
Published in The Journal of biological chemistry (27.06.2014)
Published in The Journal of biological chemistry (27.06.2014)
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Journal Article
Two-tiered enforcement of high-fidelity DNA ligation
Tumbale, Percy P., Jurkiw, Thomas J., Schellenberg, Matthew J., Riccio, Amanda A., O’Brien, Patrick J, Williams, R. Scott
Published in Nature communications (28.11.2019)
Published in Nature communications (28.11.2019)
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Journal Article
Structures of DNA-bound human ligase IV catalytic core reveal insights into substrate binding and catalysis
Kaminski, Andrea M., Tumbale, Percy P., Schellenberg, Matthew J., Williams, R. Scott, Williams, Jason G., Kunkel, Thomas A., Pedersen, Lars C., Bebenek, Katarzyna
Published in Nature communications (06.07.2018)
Published in Nature communications (06.07.2018)
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Journal Article
Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes
Palani, Sowmiya, Machida, Yuka, Alvey, Julia R., Mishra, Vandana, Welter, Allison L., Cui, Gaofeng, Bragantini , Benoît, Botuyan, Maria Victoria, Cong, Anh T. Q., Mer, Georges, Schellenberg, Matthew J., Machida, Yuichi J.
Published in Nature communications (07.03.2024)
Published in Nature communications (07.03.2024)
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Journal Article
Monocyte response to SARS-CoV-2 protein ORF8 is associated with severe COVID-19 infection in patients with chronic lymphocytic leukemia
Ruan, Gordon J, Wu, Xiaosheng, Gwin, Kimberly A, Manske, Michelle K, Abeykoon, Jithma P, Bhardwaj, Vaishali, Witter, Taylor L, Schellenberg, Matthew J, Rabe, Kari G, Kay, Neil E, Parikh, Sameer A, Witzig, Thomas E
Published in Haematologica (Roma) (01.09.2024)
Published in Haematologica (Roma) (01.09.2024)
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Journal Article
Mechanism of repair of 5′-topoisomerase II–DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2
Schellenberg, Matthew J, Appel, C Denise, Adhikari, Sanjay, Robertson, Patrick D, Ramsden, Dale A, Williams, R Scott
Published in Nature structural & molecular biology (01.12.2012)
Published in Nature structural & molecular biology (01.12.2012)
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Journal Article
DNA end processing by polynucleotide kinase/phosphatase
Schellenberg, Matthew J., Williams, R. Scott
Published in Proceedings of the National Academy of Sciences - PNAS (27.12.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (27.12.2011)
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Journal Article
BRCA1-BARD1 regulates transcription through modulating topoisomerase IIβ
Bunch, Heeyoun, Jeong, Jaehyeon, Kang, Keunsoo, Jo, Doo Sin, Cong, Anh T Q, Kim, Deukyeong, Kim, Donguk, Cho, Dong-Hyung, Lee, You Mie, Chen, Benjamin P C, Schellenberg, Matthew J, Calderwood, Stuart K
Published in Open biology (01.10.2021)
Published in Open biology (01.10.2021)
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Journal Article
Endoxifen downregulates AKT phosphorylation through protein kinase C beta 1 inhibition in ERα+ breast cancer
Jayaraman, Swaathi, Wu, Xinyan, Kalari, Krishna R., Tang, Xiaojia, Kuffel, Mary J., Bruinsma, Elizabeth S., Jalali, Shahrzad, Peterson, Kevin L., Correia, Cristina, Kudgus, Rachel A., Kaufmann, Scott H., Renuse, Santosh, Ingle, James N., Reid, Joel M., Ames, Matthew M., Fields, Alan P., Schellenberg, Matthew J., Hawse, John R., Pandey, Akhilesh, Goetz, Matthew P.
Published in NPJ breast cancer (19.12.2023)
Published in NPJ breast cancer (19.12.2023)
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Journal Article
Secreted ORF8 induces monocytic pro-inflammatory cytokines through NLRP3 pathways in patients with severe COVID-19
Wu, Xiaosheng, Manske, Michelle K., Ruan, Gordon J., Witter, Taylor L., Nowakowski, Kevin E., Abeykoon, Jithma P., Tang, Xinyi, Yu, Yue, Gwin, Kimberly A., Wu, Annie, Taupin, Vanessa, Bhardwaj, Vaishali, Paludo, Jonas, Dasari, Surendra, Dong, Haidong, Ansell, Stephen M., Badley, Andrew D., Schellenberg, Matthew J., Witzig, Thomas E.
Published in iScience (16.06.2023)
Published in iScience (16.06.2023)
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Journal Article
Molecular mechanisms of topoisomerase 2 DNA–protein crosslink resolution
Riccio, Amanda A., Schellenberg, Matthew J., Williams, R. Scott
Published in Cellular and molecular life sciences : CMLS (01.01.2020)
Published in Cellular and molecular life sciences : CMLS (01.01.2020)
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Journal Article
A Genetic Map of the Response to DNA Damage in Human Cells
Olivieri, Michele, Cho, Tiffany, Álvarez-Quilón, Alejandro, Li, Kejiao, Schellenberg, Matthew J., Zimmermann, Michal, Hustedt, Nicole, Rossi, Silvia Emma, Adam, Salomé, Melo, Henrique, Heijink, Anne Margriet, Sastre-Moreno, Guillermo, Moatti, Nathalie, Szilard, Rachel K., McEwan, Andrea, Ling, Alexanda K., Serrano-Benitez, Almudena, Ubhi, Tajinder, Feng, Sumin, Pawling, Judy, Delgado-Sainz, Irene, Ferguson, Michael W., Dennis, James W., Brown, Grant W., Cortés-Ledesma, Felipe, Williams, R. Scott, Martin, Alberto, Xu, Dongyi, Durocher, Daniel
Published in Cell (23.07.2020)
Published in Cell (23.07.2020)
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Journal Article
FRET Analysis of in Vivo Dimerization by RNA-editing Enzymes
Chilibeck, Kaari A., Wu, Tao, Liang, Chao, Schellenberg, Matthew J., Gesner, Emily M., Lynch, Jeffrey M., MacMillan, Andrew M.
Published in The Journal of biological chemistry (16.06.2006)
Published in The Journal of biological chemistry (16.06.2006)
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Journal Article
Crystal Structure of a Core Spliceosomal Protein Interface
Schellenberg, Matthew J., Edwards, Ross A., Ritchie, Dustin B., Kent, Oliver A., Golas, Monika M., Stark, Holger, Lührmann, Reinhard, Glover, J. N. Mark, MacMillan, Andrew M.
Published in Proceedings of the National Academy of Sciences - PNAS (31.01.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (31.01.2006)
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Journal Article