Metabolic Adaptation of Human CD4 + and CD8 + T-Cells to T-Cell Receptor-Mediated Stimulation
Jones, Nicholas, Cronin, James G, Dolton, Garry, Panetti, Silvia, Schauenburg, Andrea J, Galloway, Sarah A E, Sewell, Andrew K, Cole, David K, Thornton, Catherine A, Francis, Nigel J
Published in Frontiers in immunology (09.11.2017)
Published in Frontiers in immunology (09.11.2017)
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CD4+ T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features
Greenshields-Watson, Alexander, Attaf, Meriem, MacLachlan, Bruce J., Whalley, Thomas, Rius, Cristina, Wall, Aaron, Lloyd, Angharad, Hughes, Hywel, Strange, Kathryn E., Mason, Georgina H., Schauenburg, Andrea J., Hulin-Curtis, Sarah L., Geary, James, Chen, Yuan, Lauder, Sarah N., Smart, Kathryn, Vijaykrishna, Dhanasekaran, Grau, Miguel L., Shugay, Mikhail, Andrews, Robert, Dolton, Garry, Rizkallah, Pierre J., Gallimore, Awen M., Sewell, Andrew K., Godkin, Andrew J., Cole, David K.
Published in Cell reports (Cambridge) (14.07.2020)
Published in Cell reports (Cambridge) (14.07.2020)
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Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection
Miles, John J, Bulek, Anna M, Cole, David K, Gostick, Emma, Schauenburg, Andrea J A, Dolton, Garry, Venturi, Vanessa, Davenport, Miles P, Tan, Mai Ping, Burrows, Scott R, Wooldridge, Linda, Price, David A, Rizkallah, Pierre J, Sewell, Andrew K
Published in PLoS pathogens (01.11.2010)
Published in PLoS pathogens (01.11.2010)
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Peptide length determines the outcome of TCR/peptide-MHCI engagement
Ekeruche-Makinde, Julia, Miles, John J., van den Berg, Hugo A., Skowera, Ania, Cole, David K., Dolton, Garry, Schauenburg, Andrea J.A., Tan, Mai Ping, Pentier, Johanne M., Llewellyn-Lacey, Sian, Miles, Kim M., Bulek, Anna M., Clement, Mathew, Williams, Tamsin, Trimby, Andrew, Bailey, Mick, Rizkallah, Pierre, Rossjohn, Jamie, Peakman, Mark, Price, David A., Burrows, Scott R., Sewell, Andrew K., Wooldridge, Linda
Published in Blood (14.02.2013)
Published in Blood (14.02.2013)
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T-cell Receptor (TCR)-Peptide Specificity Overrides Affinity-enhancing TCR-Major Histocompatibility Complex Interactions
Cole, David K., Miles, Kim M., Madura, Florian, Holland, Christopher J., Schauenburg, Andrea J.A., Godkin, Andrew J., Bulek, Anna M., Fuller, Anna, Akpovwa, Hephzibah J.E., Pymm, Phillip G., Liddy, Nathaniel, Sami, Malkit, Li, Yi, Rizkallah, Pierre J., Jakobsen, Bent K., Sewell, Andrew K.
Published in The Journal of biological chemistry (10.01.2014)
Published in The Journal of biological chemistry (10.01.2014)
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Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope
Cole, David K, Fuller, Anna, Dolton, Garry, Zervoudi, Efthalia, Legut, Mateusz, Miles, Kim, Blanchfield, Lori, Madura, Florian, Holland, Christopher J, Bulek, Anna M, Bridgeman, John S, Miles, John J, Schauenburg, Andrea J A, Beck, Konrad, Evavold, Brian D, Rizkallah, Pierre J, Sewell, Andrew K
Published in Frontiers in immunology (10.11.2017)
Published in Frontiers in immunology (10.11.2017)
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Naive CD8+ T‐cell precursors display structured TCR repertoires and composite antigen‐driven selection dynamics
Neller, Michelle A, Ladell, Kristin, McLaren, James E, Matthews, Katherine K, Gostick, Emma, Pentier, Johanne M, Dolton, Garry, Schauenburg, Andrea JA, Koning, Dan, Fontaine Costa, Ana Isabel CA, Watkins, Thomas S, Venturi, Vanessa, Smith, Corey, Khanna, Rajiv, Miners, Kelly, Clement, Mathew, Wooldridge, Linda, Cole, David K, Baarle, Debbie, Sewell, Andrew K, Burrows, Scott R, Price, David A, Miles, John J
Published in Immunology and cell biology (01.08.2015)
Published in Immunology and cell biology (01.08.2015)
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TCR/pMHC Optimized Protein crystallization Screen
Bulek, Anna M., Madura, Florian, Fuller, Anna, Holland, Christopher J., Schauenburg, Andrea J.A., Sewell, Andrew K., Rizkallah, Pierre J., Cole, David K.
Published in Journal of immunological methods (31.08.2012)
Published in Journal of immunological methods (31.08.2012)
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Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining
Clement, Mathew, Ladell, Kristin, Ekeruche-Makinde, Julia, Miles, John J, Edwards, Emily S J, Dolton, Garry, Williams, Tamsin, Schauenburg, Andrea J A, Cole, David K, Lauder, Sarah N, Gallimore, Awen M, Godkin, Andrew J, Burrows, Scott R, Price, David A, Sewell, Andrew K, Wooldridge, Linda
Published in The Journal of immunology (1950) (15.07.2011)
Published in The Journal of immunology (1950) (15.07.2011)
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Structural basis for ineffective T‐cell responses to MHC anchor residue‐improved “heteroclitic” peptides
Madura, Florian, Rizkallah, Pierre J., Holland, Christopher J., Fuller, Anna, Bulek, Anna, Godkin, Andrew J., Schauenburg, Andrea J., Cole, David K., Sewell, Andrew K.
Published in European journal of immunology (01.02.2015)
Published in European journal of immunology (01.02.2015)
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TCR‐induced alteration of primary MHC peptide anchor residue
Madura, Florian, Rizkallah, Pierre J., Legut, Mateusz, Holland, Christopher J., Fuller, Anna, Bulek, Anna, Schauenburg, Andrea J., Trimby, Andrew, Hopkins, Jade R., Wells, Stephen A., Godkin, Andrew, Miles, John J., Sami, Malkit, Li, Yi, Liddy, Nathaniel, Jakobsen, Bent K., Loveridge, E. Joel, Cole, David K., Sewell, Andrew K.
Published in European journal of immunology (01.07.2019)
Published in European journal of immunology (01.07.2019)
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Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs
Tungatt, Katie, Bianchi, Valentina, Crowther, Michael D, Powell, Wendy E, Schauenburg, Andrea J, Trimby, Andrew, Donia, Marco, Miles, John J, Holland, Christopher J, Cole, David K, Godkin, Andrew J, Peakman, Mark, Straten, Per Thor, Svane, Inge Marie, Sewell, Andrew K, Dolton, Garry
Published in The Journal of immunology (1950) (01.01.2015)
Published in The Journal of immunology (1950) (01.01.2015)
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Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase
Cole, David K., van den Berg, Hugo A., Lloyd, Angharad, Crowther, Michael D., Beck, Konrad, Ekeruche-Makinde, Julia, Miles, John J., Bulek, Anna M., Dolton, Garry, Schauenburg, Andrea J., Wall, Aaron, Fuller, Anna, Clement, Mathew, Laugel, Bruno, Rizkallah, Pierre J., Wooldridge, Linda, Sewell, Andrew K.
Published in The Journal of biological chemistry (20.01.2017)
Published in The Journal of biological chemistry (20.01.2017)
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T-cell Receptor Specificity Maintained by Altered Thermodynamics
Madura, Florian, Rizkallah, Pierre J., Miles, Kim M., Holland, Christopher J., Bulek, Anna M., Fuller, Anna, Schauenburg, Andrea J.A., Miles, John J., Liddy, Nathaniel, Sami, Malkit, Li, Yi, Hossain, Moushumi, Baker, Brian M., Jakobsen, Bent K., Sewell, Andrew K., Cole, David K.
Published in The Journal of biological chemistry (28.06.2013)
Published in The Journal of biological chemistry (28.06.2013)
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Enhanced Detection of Antigen-Specific CD4+ T Cells Using Altered Peptide Flanking Residue Peptide-MHC Class II Multimers
Holland, Christopher J, Dolton, Garry, Scurr, Martin, Ladell, Kristin, Schauenburg, Andrea J, Miners, Kelly, Madura, Florian, Sewell, Andrew K, Price, David A, Cole, David K, Godkin, Andrew J
Published in The Journal of immunology (1950) (15.12.2015)
Published in The Journal of immunology (1950) (15.12.2015)
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Identification of human viral protein‐derived ligands recognized by individual MHCI‐restricted T‐cell receptors
Szomolay, Barbara, Liu, Jie, Brown, Paul E, Miles, John J, Clement, Mathew, Llewellyn‐Lacey, Sian, Dolton, Garry, Ekeruche‐Makinde, Julia, Lissina, Anya, Schauenburg, Andrea J, Sewell, Andrew K, Burrows, Scott R, Roederer, Mario, Price, David A, Wooldridge, Linda, Berg, Hugo A
Published in Immunology and cell biology (01.07.2016)
Published in Immunology and cell biology (01.07.2016)
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A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape
Kløverpris, Henrik N, Cole, David K, Fuller, Anna, Carlson, Jonathan, Beck, Konrad, Schauenburg, Andrea J, Rizkallah, Pierre J, Buus, Søren, Sewell, Andrew K, Goulder, Philip
Published in Retrovirology (20.02.2015)
Published in Retrovirology (20.02.2015)
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Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens
MacLachlan, Bruce J, Greenshields-Watson, Alexander, Mason, Georgina H, Schauenburg, Andrea J, Bianchi, Valentina, Rizkallah, Pierre J, Sewell, Andrew K, Fuller, Anna, Cole, David K
Published in Journal of visualized experiments (06.02.2017)
Published in Journal of visualized experiments (06.02.2017)
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Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens
MacLachlan, Bruce J., Greenshields-Watson, Alexander, Mason, Georgina H, Schauenburg, Andrea J, Bianchi, Valentina, Rizkallah, Pierre J, Sewell, Andrew K, Fuller, Anna, Cole, David K
Published in Journal of visualized experiments (06.02.2017)
Published in Journal of visualized experiments (06.02.2017)
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