Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus
Jenks, Scott A., Cashman, Kevin S., Zumaquero, Esther, Marigorta, Urko M., Patel, Aakash V., Wang, Xiaoqian, Tomar, Deepak, Woodruff, Matthew C., Simon, Zoe, Bugrovsky, Regina, Blalock, Emily L., Scharer, Christopher D., Tipton, Christopher M., Wei, Chungwen, Lim, S. Sam, Petri, Michelle, Niewold, Timothy B., Anolik, Jennifer H., Gibson, Greg, Lee, F. Eun-Hyung, Boss, Jeremy M., Lund, Frances E., Sanz, Ignacio
Published in Immunity (Cambridge, Mass.) (16.10.2018)
Published in Immunity (Cambridge, Mass.) (16.10.2018)
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Journal Article
Lactobacilli Modulate Epithelial Cytoprotection through the Nrf2 Pathway
Jones, Rheinallt M., Desai, Chirayu, Darby, Trevor M., Luo, Liping, Wolfarth, Alexandra A., Scharer, Christopher D., Ardita, Courtney S., Reedy, April R., Keebaugh, Erin S., Neish, Andrew S.
Published in Cell reports (Cambridge) (25.08.2015)
Published in Cell reports (Cambridge) (25.08.2015)
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Global DNA methylation remodeling accompanies CD8 T cell effector function
Scharer, Christopher D, Barwick, Benjamin G, Youngblood, Benjamin A, Ahmed, Rafi, Boss, Jeremy M
Published in The Journal of immunology (1950) (15.09.2013)
Published in The Journal of immunology (1950) (15.09.2013)
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Journal Article
PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program
Hashimoto, Masao, Araki, Koichi, Cardenas, Maria A., Li, Peng, Jadhav, Rohit R., Kissick, Haydn T., Hudson, William H., McGuire, Donald J., Obeng, Rebecca C., Wieland, Andreas, Lee, Judong, McManus, Daniel T., Ross, James L., Im, Se Jin, Lee, Junghwa, Lin, Jian-Xin, Hu, Bin, West, Erin E., Scharer, Christopher D., Freeman, Gordon J., Sharpe, Arlene H., Ramalingam, Suresh S., Pellerin, Alex, Teichgräber, Volker, Greenleaf, William J., Klein, Christian, Goronzy, Jorg J., Umaña, Pablo, Leonard, Warren J., Smith, Kendall A., Ahmed, Rafi
Published in Nature (London) (06.10.2022)
Published in Nature (London) (06.10.2022)
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Journal Article
NF-κB regulates PD-1 expression in macrophages
Bally, Alexander P R, Lu, Peiyuan, Tang, Yan, Austin, James W, Scharer, Christopher D, Ahmed, Rafi, Boss, Jeremy M
Published in The Journal of immunology (1950) (01.05.2015)
Published in The Journal of immunology (1950) (01.05.2015)
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Journal Article
B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation
Barwick, Benjamin G., Scharer, Christopher D., Martinez, Ryan J., Price, Madeline J., Wein, Alexander N., Haines, Robert R., Bally, Alexander P. R., Kohlmeier, Jacob E., Boss, Jeremy M.
Published in Nature communications (15.05.2018)
Published in Nature communications (15.05.2018)
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Journal Article
Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8+ T cells
Hayward, Sarah L., Scharer, Christopher D., Cartwright, Emily K., Takamura, Shiki, Li, Zheng-Rong Tiger, Boss, Jeremy M., Kohlmeier, Jacob E.
Published in Nature immunology (01.03.2020)
Published in Nature immunology (01.03.2020)
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Journal Article
Signaling through the Inhibitory Fc Receptor FcγRIIB Induces CD8+ T Cell Apoptosis to Limit T Cell Immunity
Morris, Anna B., Farley, Clara R., Pinelli, David F., Adams, Layne E., Cragg, Mark S., Boss, Jeremy M., Scharer, Christopher D., Fribourg, Miguel, Cravedi, Paolo, Heeger, Peter S., Ford, Mandy L.
Published in Immunity (Cambridge, Mass.) (14.01.2020)
Published in Immunity (Cambridge, Mass.) (14.01.2020)
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Journal Article
Epigenetic programming underpins B cell dysfunction in human SLE
Scharer, Christopher D., Blalock, Emily L., Mi, Tian, Barwick, Benjamin G., Jenks, Scott A., Deguchi, Tsuneo, Cashman, Kevin S., Neary, Bridget E., Patterson, Dillon G., Hicks, Sakeenah L., Khosroshahi, Arezou, Eun-Hyung Lee, F., Wei, Chungwen, Sanz, Iñaki, Boss, Jeremy M.
Published in Nature immunology (01.08.2019)
Published in Nature immunology (01.08.2019)
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Journal Article
EZH2 Represses the B Cell Transcriptional Program and Regulates Antibody-Secreting Cell Metabolism and Antibody Production
Guo, Muyao, Price, Madeline J, Patterson, Dillon G, Barwick, Benjamin G, Haines, Robert R, Kania, Anna K, Bradley, John E, Randall, Troy D, Boss, Jeremy M, Scharer, Christopher D
Published in The Journal of immunology (1950) (01.02.2018)
Published in The Journal of immunology (1950) (01.02.2018)
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Journal Article
Obesity-induced dysregulation of skin-resident PPARγ + Treg cells promotes IL-17A-mediated psoriatic inflammation
Sivasami, Pulavendran, Elkins, Cody, Diaz-Saldana, Pamela P, Goss, Kyndal, Peng, Amy, Hamersky, 4th, Michael, Bae, Jennifer, Xu, Miaoer, Pollack, Brian P, Horwitz, Edwin M, Scharer, Christopher D, Seldin, Lindsey, Li, Chaoran
Published in Immunity (Cambridge, Mass.) (08.08.2023)
Published in Immunity (Cambridge, Mass.) (08.08.2023)
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Journal Article
ATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in naïve SLE B cells
Scharer, Christopher D., Blalock, Emily L., Barwick, Benjamin G., Haines, Robert R., Wei, Chungwen, Sanz, Ignacio, Boss, Jeremy M.
Published in Scientific reports (01.06.2016)
Published in Scientific reports (01.06.2016)
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Journal Article
Epigenetic gene regulation in plasma cells
Patterson, Dillon G., Kania, Anna K., Zuo, Zhihong, Scharer, Christopher D., Boss, Jeremy M.
Published in Immunological reviews (01.09.2021)
Published in Immunological reviews (01.09.2021)
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Journal Article
T-bet Transcription Factor Promotes Antibody-Secreting Cell Differentiation by Limiting the Inflammatory Effects of IFN-γ on B Cells
Stone, Sara L., Peel, Jessica N., Scharer, Christopher D., Risley, Christopher A., Chisolm, Danielle A., Schultz, Michael D., Yu, Bingfei, Ballesteros-Tato, André, Wojciechowski, Wojciech, Mousseau, Betty, Misra, Ravi S., Hanidu, Adedayo, Jiang, Huiping, Qi, Zhenhao, Boss, Jeremy M., Randall, Troy D., Brodeur, Scott R., Goldrath, Ananda W., Weinmann, Amy S., Rosenberg, Alexander F., Lund, Frances E.
Published in Immunity (Cambridge, Mass.) (21.05.2019)
Published in Immunity (Cambridge, Mass.) (21.05.2019)
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Journal Article
An IRF4–MYC–mTORC1 Integrated Pathway Controls Cell Growth and the Proliferative Capacity of Activated B Cells during B Cell Differentiation In Vivo
Patterson, Dillon G., Kania, Anna K., Price, Madeline J., Rose, James R., Scharer, Christopher D., Boss, Jeremy M.
Published in The Journal of immunology (1950) (01.10.2021)
Published in The Journal of immunology (1950) (01.10.2021)
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