Plant natural fragments, an innovative approach for drug discovery
David, Bruno, Grondin, Antonio, Schambel, Philippe, Vitorino, Marc, Zeyer, Denis
Published in Phytochemistry reviews (01.10.2020)
Published in Phytochemistry reviews (01.10.2020)
Get full text
Journal Article
Synthesis and Evaluation of Analogues of N‑Phthaloyl‑l‑tryptophan (RG108) as Inhibitors of DNA Methyltransferase 1
Asgatay, Saâdia, Champion, Christine, Marloie, Gaël, Drujon, Thierry, Senamaud-Beaufort, Catherine, Ceccaldi, Alexandre, Erdmann, Alexandre, Rajavelu, Arumugam, Schambel, Philippe, Jeltsch, Albert, Lequin, Olivier, Karoyan, Philippe, Arimondo, Paola B., Guianvarc’h, Dominique
Published in Journal of medicinal chemistry (23.01.2014)
Published in Journal of medicinal chemistry (23.01.2014)
Get full text
Journal Article
Design, Synthesis and Biological Evaluation of 4-Amino-N-(4-aminophenyl)benzamide Analogues of Quinoline-Based SGI-1027 as Inhibitors of DNA Methylation
Rilova, Elodie, Erdmann, Alexandre, Gros, Christina, Masson, Véronique, Aussagues, Yannick, Poughon-Cassabois, Valérie, Rajavelu, Arumugam, Jeltsch, Albert, Menon, Yoann, Novosad, Natacha, Gregoire, Jean-Marc, Vispé, Stéphane, Schambel, Philippe, Ausseil, Fréderic, Sautel, François, Arimondo, Paola B., Cantagrel, Frédéric
Published in ChemMedChem (01.03.2014)
Published in ChemMedChem (01.03.2014)
Get full text
Journal Article
Identification and optimization of hydrazone-gallate derivatives as specific inhibitors of DNA methyltransferase 3A
Erdmann, Alexandre, Menon, Yoann, Gros, Christina, Masson, Véronique, Aussagues, Yannick, Ausseil, Fréderic, Novosad, Natacha, Schambel, Philippe, Baltas, Michel, Arimondo, Paola B
Published in Future medicinal chemistry (01.03.2016)
Published in Future medicinal chemistry (01.03.2016)
Get full text
Journal Article
Meroterpenes from Dichrostachys cinerea Inhibit Protein Farnesyl Transferase Activity
Long, Christophe, Marcourt, Laurence, Raux, Roselyne, David, Bruno, Gau, Christelle, Menendez, Christophe, Gao, Min, Laroche, Marie-France, Schambel, Philippe, Delaude, Clément, Ausseil, Frédéric, Lavaud, Catherine, Massiot, Georges
Published in Journal of natural products (Washington, D.C.) (23.10.2009)
Published in Journal of natural products (Washington, D.C.) (23.10.2009)
Get full text
Journal Article
Meroterpenes from Dichrostachys cinerea Inhibit Protein Farnesyl Transferase Activity
Long, Christophe, Marcourt, Laurence, Raux, Roselyne, David, Bruno, Gau, Christelle, Menendez, Christophe, Gao, Min, Laroche, Marie-France, Schambel, Philippe, Delaude, Clément, Ausseil, Frédéric, Lavaud, Catherine, Massiot, Georges
Published in Journal of natural products (Washington, D.C.) (25.06.2010)
Published in Journal of natural products (Washington, D.C.) (25.06.2010)
Get full text
Journal Article
Binding of Arylpiperazines, (Aryloxy)propanolamines, and Tetrahydropyridylindoles to the 5-HT1A Receptor: Contribution of the Molecular Lipophilicity Potential to Three-Dimensional Quantitative Structure−Affinity Relationship Models
Gaillard, Patrick, Carrupt, Pierre-Alain, Testa, Bernard, Schambel, Philippe
Published in Journal of medicinal chemistry (05.01.1996)
Published in Journal of medicinal chemistry (05.01.1996)
Get full text
Journal Article
Synthesis and evaluation of a novel series of farnesyl protein transferase inhibitors as non-peptidic CAAX tetrapeptide analogues
Perez, Michel, Maraval, Catherine, Dumond, Stephan, Lamothe, Marie, Schambel, Philippe, Etiévant, Chantal, Hill, Bridget
Published in Bioorganic & medicinal chemistry letters (17.04.2003)
Published in Bioorganic & medicinal chemistry letters (17.04.2003)
Get full text
Journal Article
Differentiation between Partial Agonists and Neutral 5-HT1B Antagonists by Chemical Modulation of 3-[3-(N,N-Dimethylamino)propyl]-4-hydroxy- N-[4-(pyridin-4-yl)phenyl]benzamide (GR-55562)
Lamothe, Marie, Pauwels, Petrus J, Belliard, Karine, Schambel, Philippe, Halazy, Serge
Published in Journal of medicinal chemistry (24.10.1997)
Published in Journal of medicinal chemistry (24.10.1997)
Get full text
Journal Article
New Substituted 1-(2,3-Dihydrobenzo[1,4]dioxin-2-ylmethyl)piperidin-4-yl Derivatives with α2-Adrenoceptor Antagonist Activity
Mayer, Patrice, Brunel, Pascale, Chaplain, Céline, Piedecoq, Christel, Calmel, Francis, Schambel, Philippe, Chopin, Philippe, Wurch, Thierry, Pauwels, Petrus J, Marien, Marc, Vidaluc, Jean-Louis, Imbert, Thierry
Published in Journal of medicinal chemistry (05.10.2000)
Published in Journal of medicinal chemistry (05.10.2000)
Get full text
Journal Article
New Substituted 1-(2,3-Dihydrobenzo[1,4]dioxin-2-ylmethyl)piperidin-4-yl Derivatives with α 2 -Adrenoceptor Antagonist Activity
Mayer, Patrice, Brunel, Pascale, Chaplain, Céline, Piedecoq, Christel, Calmel, Francis, Schambel, Philippe, Chopin, Philippe, Wurch, Thierry, Pauwels, Petrus J., Marien, Marc, Vidaluc, Jean-Louis, Imbert, Thierry
Published in Journal of medicinal chemistry (01.10.2000)
Published in Journal of medicinal chemistry (01.10.2000)
Get full text
Journal Article
Binding of Arylpiperazines, (Aryloxy)propanolamines, and Tetrahydropyridylindoles to the 5-HT 1A Receptor: Contribution of the Molecular Lipophilicity Potential to Three-Dimensional Quantitative Structure−Affinity Relationship Models
Gaillard, Patrick, Carrupt, Pierre-Alain, Testa, Bernard, Schambel, Philippe
Published in Journal of medicinal chemistry (01.01.1996)
Published in Journal of medicinal chemistry (01.01.1996)
Get full text
Journal Article
Differentiation between Partial Agonists and Neutral 5-HT 1B Antagonists by Chemical Modulation of 3-[3-( N,N -Dimethylamino)propyl]-4-hydroxy- N -[4-(pyridin-4-yl)phenyl]benzamide (GR-55562)
Lamothe, Marie, Pauwels, Petrus J., Belliard, Karine, Schambel, Philippe, Halazy, Serge
Published in Journal of medicinal chemistry (01.10.1997)
Published in Journal of medicinal chemistry (01.10.1997)
Get full text
Journal Article
PYRAZOLOPYRIDINE DERIVATIVES AS ANTICANCER AGENT
MAYER, PATRICE, BEDJEGUELAL, KARIM, RABOT, RÉMI, BIENAYME, HUGUES, SCHAMBEL, PHILIPPE, RAHIER, NICOLAS, KALOUN, EL BACHIR, MARCHAND, ARNAUD
Year of Publication 10.06.2015
Get full text
Year of Publication 10.06.2015
Patent
Pyrazolopyridine derivatives as anticancer agent
RAHIER NICOLAS, BIENAYME HUGUES, MARCHAND ARNAUD, KALOUN EL BACHIR, RABOT RÉMI, SCHAMBEL PHILIPPE, BEDJEGUELAL KARIM, MAYER PATRICE
Year of Publication 18.11.2014
Get full text
Year of Publication 18.11.2014
Patent
An improved synthesis of 18-norandrost-4-ene-3,17-dione
Davioud, Elisabeth, Schambel, Philippe, Viger, Antoinette, Marquet, Andrée
Published in Steroids (01.03.1993)
Published in Steroids (01.03.1993)
Get full text
Journal Article
DERIVES PYRAZOLOPYRIDINES EN TANT QU'AGENT ANTICANCEREUX
RABOT, REMI, RAHIER NICOLAS, BIENAYME HUGUES, MARCHAND ARNAUD, BEDJEGUELAL, KARIM, SCHAMBEL PHILIPPE, KALOUN, EL BACHIR, MAYER PATRICE
Year of Publication 26.09.2014
Get full text
Year of Publication 26.09.2014
Patent
PYRAZOLOPYRIDINE DERIVATIVES AS ANTICANCER AGENT
RAHIER NICOLAS, BIENAYME HUGUES, MARCHAND ARNAUD, RABOT REMI, KALOUN EL BACHIR, SCHAMBEL PHILIPPE, BEDJEGUELAL KARIM, MAYER PATRICE
Year of Publication 27.09.2012
Get full text
Year of Publication 27.09.2012
Patent