Small Nucleolar RNAs U32a, U33, and U35a Are Critical Mediators of Metabolic Stress
Michel, Carlos I., Holley, Christopher L., Scruggs, Benjamin S., Sidhu, Rohini, Brookheart, Rita T., Listenberger, Laura L., Behlke, Mark A., Ory, Daniel S., Schaffer, Jean E.
Published in Cell metabolism (06.07.2011)
Published in Cell metabolism (06.07.2011)
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Palmitate and Lipopolysaccharide Trigger Synergistic Ceramide Production in Primary Macrophages
Schilling, Joel D., Machkovech, Heather M., He, Li, Sidhu, Rohini, Fujiwara, Hideji, Weber, Kassandra, Ory, Daniel S., Schaffer, Jean E.
Published in The Journal of biological chemistry (01.02.2013)
Published in The Journal of biological chemistry (01.02.2013)
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Ceramide Remodeling and Risk of Cardiovascular Events and Mortality
Peterson, Linda R., Xanthakis, Vanessa, Duncan, Meredith S., Gross, Stefan, Friedrich, Nele, Völzke, Henry, Felix, Stephan B., Jiang, Hui, Sidhu, Rohini, Nauck, Matthias, Jiang, Xuntian, Ory, Daniel S., Dörr, Marcus, Vasan, Ramachandran S., Schaffer, Jean E.
Published in Journal of the American Heart Association (15.05.2018)
Published in Journal of the American Heart Association (15.05.2018)
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DGAT1 Expression Increases Heart Triglyceride Content but Ameliorates Lipotoxicity
Liu, Li, Shi, XiaoJing, Bharadwaj, Kalyani G., Ikeda, Shota, Yamashita, Haruyo, Yagyu, Hiroaki, Schaffer, Jean E., Yu, Yi-Hao, Goldberg, Ira J.
Published in The Journal of biological chemistry (25.12.2009)
Published in The Journal of biological chemistry (25.12.2009)
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A murine Niemann-Pick C1 I1061T knock-in model recapitulates the pathological features of the most prevalent human disease allele
Praggastis, Maria, Tortelli, Brett, Zhang, Jessie, Fujiwara, Hideji, Sidhu, Rohini, Chacko, Anita, Chen, Zhouji, Chung, Chan, Lieberman, Andrew P, Sikora, Jakub, Davidson, Cristin, Walkley, Steven U, Pipalia, Nina H, Maxfield, Frederick R, Schaffer, Jean E, Ory, Daniel S
Published in The Journal of neuroscience (27.05.2015)
Published in The Journal of neuroscience (27.05.2015)
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Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death
Borradaile, Nica M., Han, Xianlin, Harp, Jeffrey D., Gale, Sarah E., Ory, Daniel S., Schaffer, Jean E.
Published in Journal of lipid research (01.12.2006)
Published in Journal of lipid research (01.12.2006)
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A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma[S]
Jiang, Xuntian, Sidhu, Rohini, Porter, Forbes D., Yanjanin, Nicole M., Speak, Anneliese O., te Vruchte, Danielle Taylor, Platt, Frances M., Fujiwara, Hideji, Scherrer, David E., Zhang, Jessie, Dietzen, Dennis J., Schaffer, Jean E., Ory, Daniel S.
Published in Journal of lipid research (01.07.2011)
Published in Journal of lipid research (01.07.2011)
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Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis
Sletten, Arthur C., Davidson, Jessica W., Yagabasan, Busra, Moores, Samantha, Schwaiger-Haber, Michaela, Fujiwara, Hideji, Gale, Sarah, Jiang, Xuntian, Sidhu, Rohini, Gelman, Susan J., Zhao, Shuang, Patti, Gary J., Ory, Daniel S., Schaffer, Jean E.
Published in Nature communications (01.09.2021)
Published in Nature communications (01.09.2021)
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Cytosolic Accumulation of Small Nucleolar RNAs (snoRNAs) Is Dynamically Regulated by NADPH Oxidase
Holley, Christopher L., Li, Melissa W., Scruggs, Benjamin S., Matkovich, Scot J., Ory, Daniel S., Schaffer, Jean E.
Published in The Journal of biological chemistry (01.05.2015)
Published in The Journal of biological chemistry (01.05.2015)
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N-acyl-O-phosphocholineserines: structures of a novel class of lipids that are biomarkers for Niemann-Pick C1 disease
Sidhu, Rohini, Mondjinou, Yawo, Qian, Mingxing, Song, Haowei, Kumar, Arun Babu, Hong, Xinying, Hsu, Fong-Fu, Dietzen, Dennis J., Yanjanin, Nicole M., Porter, Forbes D., Berry-Kravis, Elizabeth, Vite, Charles H., Gelb, Michael H., Schaffer, Jean E., Ory, Daniel S., Jiang, Xuntian
Published in Journal of lipid research (01.08.2019)
Published in Journal of lipid research (01.08.2019)
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Development of a bile acid-based newborn screen for Niemann-Pick disease type C
Jiang, Xuntian, Sidhu, Rohini, Mydock-McGrane, Laurel, Hsu, Fong-Fu, Covey, Douglas F, Scherrer, David E, Earley, Brian, Gale, Sarah E, Farhat, Nicole Y, Porter, Forbes D, Dietzen, Dennis J, Orsini, Joseph J, Berry-Kravis, Elizabeth, Zhang, Xiaokui, Reunert, Janice, Marquardt, Thorsten, Runz, Heiko, Giugliani, Roberto, Schaffer, Jean E, Ory, Daniel S
Published in Science translational medicine (04.05.2016)
Published in Science translational medicine (04.05.2016)
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Alterations in plasma triglycerides and ceramides: links with cardiac function in humans with type 2 diabetes
Peterson, Linda R., Jiang, Xuntian, Chen, Ling, Goldberg, Anne C., Farmer, Marsha S., Ory, Daniel S., Schaffer, Jean E.
Published in Journal of lipid research (01.07.2020)
Published in Journal of lipid research (01.07.2020)
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Journal Article
Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease
Porter, Forbes D, Scherrer, David E, Lanier, Michael H, Langmade, S Joshua, Molugu, Vasumathi, Gale, Sarah E, Olzeski, Dana, Sidhu, Rohini, Dietzen, Dennis J, Fu, Rao, Wassif, Christopher A, Yanjanin, Nicole M, Marso, Steven P, House, John, Vite, Charles, Schaffer, Jean E, Ory, Daniel S
Published in Science translational medicine (03.11.2010)
Published in Science translational medicine (03.11.2010)
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A validated LC-MS/MS assay for quantification of 24(S)-hydroxycholesterol in plasma and cerebrospinal fluid
Sidhu, Rohini, Jiang, Hui, Farhat, Nicole Y., Carrillo-Carrasco, Nuria, Woolery, Myra, Ottinger, Elizabeth, Porter, Forbes D., Schaffer, Jean E., Ory, Daniel S., Jiang, Xuntian
Published in Journal of lipid research (01.06.2015)
Published in Journal of lipid research (01.06.2015)
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Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking[S]
Feltes, McKenna, Moores, Samantha, Gale, Sarah E., Krishnan, Kathiresan, Mydock-McGrane, Laurel, Covey, Douglas F., Ory, Daniel S., Schaffer, Jean E.
Published in Journal of lipid research (01.03.2019)
Published in Journal of lipid research (01.03.2019)
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Journal Article
Identification of Niemann-Pick C1 disease biomarkers through sphingolipid profiling
Fan, Martin, Sidhu, Rohini, Fujiwara, Hideji, Tortelli, Brett, Zhang, Jessie, Davidson, Cristin, Walkley, Steven U., Bagel, Jessica H., Vite, Charles, Yanjanin, Nicole M., Porter, Forbes D., Schaffer, Jean E., Ory, Daniel S.
Published in Journal of lipid research (01.10.2013)
Published in Journal of lipid research (01.10.2013)
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