Best practices and benchmarks for intact protein analysis for top-down mass spectrometry
Donnelly, Daniel P., Rawlins, Catherine M., DeHart, Caroline J., Fornelli, Luca, Schachner, Luis F., Lin, Ziqing, Lippens, Jennifer L., Aluri, Krishna C., Sarin, Richa, Chen, Bifan, Lantz, Carter, Jung, Wonhyeuk, Johnson, Kendall R., Koller, Antonius, Wolff, Jeremy J., Campuzano, Iain D. G., Auclair, Jared R., Ivanov, Alexander R., Whitelegge, Julian P., Paša-Tolić, Ljiljana, Chamot-Rooke, Julia, Danis, Paul O., Smith, Lloyd M., Tsybin, Yury O., Loo, Joseph A., Ge, Ying, Kelleher, Neil L., Agar, Jeffrey N.
Published in Nature methods (01.07.2019)
Published in Nature methods (01.07.2019)
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Journal Article
Native top-down mass spectrometry provides insights into the copper centers of membrane-bound methane monooxygenase
Ro, Soo Y., Schachner, Luis F., Koo, Christopher W., Purohit, Rahul, Remis, Jonathan P., Kenney, Grace E., Liauw, Brandon W., Thomas, Paul M., Patrie, Steven M., Kelleher, Neil L., Rosenzweig, Amy C.
Published in Nature communications (17.06.2019)
Published in Nature communications (17.06.2019)
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Journal Article
Top-down characterization of endogenous protein complexes with native proteomics
Skinner, Owen S, Haverland, Nicole A, Fornelli, Luca, Melani, Rafael D, Do Vale, Luis H F, Seckler, Henrique S, Doubleday, Peter F, Schachner, Luis F, Srzentić, Kristina, Kelleher, Neil L, Compton, Philip D
Published in Nature chemical biology (01.01.2018)
Published in Nature chemical biology (01.01.2018)
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Journal Article
High-Throughput, Quantitative Analysis of Peptide-Exchanged MHCI Complexes by Native Mass Spectrometry
Schachner, Luis F., Phung, Wilson, Han, Guanghui, Darwish, Martine, Bell, Ashley, Mellors, J. Scott, Srzentic, Kristina, Huguet, Romain, Blanchette, Craig, Sandoval, Wendy
Published in Analytical chemistry (Washington) (25.10.2022)
Published in Analytical chemistry (Washington) (25.10.2022)
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Journal Article
The biosynthesis of methanobactin
Kenney, Grace E, Dassama, Laura M K, Pandelia, Maria-Eirini, Gizzi, Anthony S, Martinie, Ryan J, Gao, Peng, DeHart, Caroline J, Schachner, Luis F, Skinner, Owen S, Ro, Soo Y, Zhu, Xiao, Sadek, Monica, Thomas, Paul M, Almo, Steven C, Bollinger, Jr, J Martin, Krebs, Carsten, Kelleher, Neil L, Rosenzweig, Amy C
Published in Science (American Association for the Advancement of Science) (23.03.2018)
Published in Science (American Association for the Advancement of Science) (23.03.2018)
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Journal Article
Individual Ion Mass Spectrometry Enhances the Sensitivity and Sequence Coverage of Top-Down Mass Spectrometry
Kafader, Jared O, Durbin, Kenneth R, Melani, Rafael D, Des Soye, Benjamin J, Schachner, Luis F, Senko, Michael W, Compton, Philip D, Kelleher, Neil L
Published in Journal of proteome research (06.03.2020)
Published in Journal of proteome research (06.03.2020)
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Journal Article
Exposing the molecular heterogeneity of glycosylated biotherapeutics
Schachner, Luis F., Mullen, Christopher, Phung, Wilson, Hinkle, Joshua D., Beardsley, Michelle Irwin, Bentley, Tracy, Day, Peter, Tsai, Christina, Sukumaran, Siddharth, Baginski, Tomasz, DiCara, Danielle, Agard, Nicholas J., Masureel, Matthieu, Gober, Joshua, ElSohly, Adel M., Melani, Rafael, Syka, John E. P., Huguet, Romain, Marty, Michael T., Sandoval, Wendy
Published in Nature communications (16.04.2024)
Published in Nature communications (16.04.2024)
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Journal Article
Separation and Characterization of Endogenous Nucleosomes by Native Capillary Zone Electrophoresis–Top-Down Mass Spectrometry
Jooß, Kevin, Schachner, Luis F, Watson, Rachel, Gillespie, Zachary B, Howard, Sarah A, Cheek, Marcus A, Meiners, Matthew J, Sobh, Amin, Licht, Jonathan D, Keogh, Michael-Christopher, Kelleher, Neil L
Published in Analytical chemistry (Washington) (30.03.2021)
Published in Analytical chemistry (Washington) (30.03.2021)
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Journal Article
Top-down proteomics: Where we are, where we are going?
Fornelli, Luca, Toby, Timothy K., Schachner, Luis F., Doubleday, Peter F., Srzentić, Kristina, DeHart, Caroline J., Kelleher, Neil L.
Published in Journal of proteomics (20.03.2018)
Published in Journal of proteomics (20.03.2018)
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Journal Article
Decoding the protein composition of whole nucleosomes with Nuc-MS
Schachner, Luis F., Jooß, Kevin, Morgan, Marc A., Piunti, Andrea, Meiners, Matthew J., Kafader, Jared O., Lee, Alexander S., Iwanaszko, Marta, Cheek, Marcus A., Burg, Jonathan M., Howard, Sarah A., Keogh, Michael-Christopher, Shilatifard, Ali, Kelleher, Neil L.
Published in Nature methods (01.03.2021)
Published in Nature methods (01.03.2021)
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Journal Article
Repurposed HisC Aminotransferases Complete the Biosynthesis of Some Methanobactins
Park, Yun Ji, Kenney, Grace E, Schachner, Luis F, Kelleher, Neil L, Rosenzweig, Amy C
Published in Biochemistry (Easton) (26.06.2018)
Published in Biochemistry (Easton) (26.06.2018)
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Journal Article
Native vs Denatured: An in Depth Investigation of Charge State and Isotope Distributions
Kafader, Jared O, Melani, Rafael D, Schachner, Luis F, Ives, Ashley N, Patrie, Steven M, Kelleher, Neil L, Compton, Philip D
Published in Journal of the American Society for Mass Spectrometry (04.03.2020)
Published in Journal of the American Society for Mass Spectrometry (04.03.2020)
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Journal Article
Standard Proteoforms and Their Complexes for Native Mass Spectrometry
Schachner, Luis F., Ives, Ashley N., McGee, John P., Melani, Rafael D., Kafader, Jared O., Compton, Philip D., Patrie, Steven M., Kelleher, Neil L.
Published in Journal of the American Society for Mass Spectrometry (01.07.2019)
Published in Journal of the American Society for Mass Spectrometry (01.07.2019)
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Journal Article
Using 10,000 Fragment Ions to Inform Scoring in Native Top-down Proteomics
Ives, Ashley N, Su, Taojunfeng, Durbin, Kenneth R, Early, Bryan P, dos Santos Seckler, Henrique, Fellers, Ryan T, LeDuc, Richard D, Schachner, Luis F, Patrie, Steven M, Kelleher, Neil L
Published in Journal of the American Society for Mass Spectrometry (01.07.2020)
Published in Journal of the American Society for Mass Spectrometry (01.07.2020)
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Journal Article
Revving an Engine of Human Metabolism: Activity Enhancement of Triosephosphate Isomerase via Hemi-Phosphorylation
Schachner, Luis F., Soye, Benjamin Des, Ro, Soo, Kenney, Grace E., Ives, Ashley N., Su, Taojunfeng, Goo, Young Ah, Jewett, Michael C., Rosenzweig, Amy C., Kelleher, Neil L.
Published in ACS chemical biology (21.10.2022)
Published in ACS chemical biology (21.10.2022)
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Journal Article
Reassembling protein complexes after controlled disassembly by top-down mass spectrometry in native mode
Schachner, Luis F., Tran, Denise P., Lee, Alexander S., McGee, John P., Jooss, Kevin, Durbin, Kenneth R., Seckler, Henrique S., Adams, Lauren, Cline, Erika N., Melani, Rafael D., Ives, Ashley N., Soye, Benjamin Des, Kelleher, Neil L., Patrie, Steven M.
Published in International journal of mass spectrometry (01.07.2021)
Published in International journal of mass spectrometry (01.07.2021)
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Journal Article
A novel crosslinking protocol stabilizes amyloid β oligomers capable of inducing Alzheimer's‐associated pathologies
Cline, Erika N., Das, Arighno, Bicca, Maíra Assunção, Mohammad, Saad N., Schachner, Luis F., Kamel, Josette M., DiNunno, Nadia, Weng, Anthea, Paschall, Jacob D., Bu, Riana Lo, Khan, Faraz M., Rollins, Madeline G., Ives, Ashley N., Shekhawat, Gajendra, Nunes‐Tavares, Nilson, de Mello, Fernando G., Compton, Philip D., Kelleher, Neil L., Klein, William L.
Published in Journal of neurochemistry (01.03.2019)
Published in Journal of neurochemistry (01.03.2019)
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Journal Article
Development of novel methods for non-canonical myeloma protein analysis with an innovative adaptation of immunofixation electrophoresis, native top-down mass spectrometry, and middle-down de novo sequencing
Deighan, W. Ian, Winton, Valerie J., Melani, Rafael D., Anderson, Lissa C., McGee, John P., Schachner, Luis F., Barnidge, David, Murray, David, Alexander, H. Denis, Gibson, David S., Deery, Michael J., McNicholl, Feargal P., McLaughlin, Joseph, Kelleher, Neil L., Thomas, Paul M.
Published in Clinical chemistry and laboratory medicine (26.03.2021)
Published in Clinical chemistry and laboratory medicine (26.03.2021)
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Journal Article
Characterization of Chain Pairing Variants of Bispecific IgG Expressed in a Single Host Cell by High-Resolution Native and Denaturing Mass Spectrometry
Schachner, Luis, Han, Guanghui, Dillon, Michael, Zhou, Jianhui, McCarty, Luke, Ellerman, Diego, Yin, Yiyuan, Spiess, Christoph, Lill, Jennie R, Carter, Paul J, Sandoval, Wendy
Published in Analytical chemistry (Washington) (20.12.2016)
Published in Analytical chemistry (Washington) (20.12.2016)
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Journal Article