BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma
Laubscher, Dominik, Gryder, Berkley E., Sunkel, Benjamin D., Andresson, Thorkell, Wachtel, Marco, Das, Sudipto, Roschitzki, Bernd, Wolski, Witold, Wu, Xiaoli S., Chou, Hsien-Chao, Song, Young K., Wang, Chaoyu, Wei, Jun S., Wang, Meng, Wen, Xinyu, Ngo, Quy Ai, Marques, Joana G., Vakoc, Christopher R., Schäfer, Beat W., Stanton, Benjamin Z., Khan, Javed
Published in Nature communications (26.11.2021)
Published in Nature communications (26.11.2021)
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Fenretinide induces a new form of dynamin-dependent cell death in pediatric sarcoma
Brack, Eva, Wachtel, Marco, Wolf, Anja, Kaech, Andres, Ziegler, Urs, Schäfer, Beat W.
Published in Cell death and differentiation (01.08.2020)
Published in Cell death and differentiation (01.08.2020)
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Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity
Manzella, Gabriele, Schreck, Leonie D., Breunis, Willemijn B., Molenaar, Jan, Merks, Hans, Barr, Frederic G., Sun, Wenyue, Römmele, Michaela, Zhang, Luduo, Tchinda, Joelle, Ngo, Quy A., Bode, Peter, Delattre, Olivier, Surdez, Didier, Rekhi, Bharat, Niggli, Felix K., Schäfer, Beat W., Wachtel, Marco
Published in Nature communications (15.09.2020)
Published in Nature communications (15.09.2020)
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A combinatorial drug screen in PDX-derived primary rhabdomyosarcoma cells identifies the NOXA - BCL-XL/MCL-1 balance as target for re-sensitization to first-line therapy in recurrent tumors
Manzella, Gabriele, Moonamale, Devmini C., Römmele, Michaela, Bode, Peter, Wachtel, Marco, Schäfer, Beat W.
Published in Neoplasia (New York, N.Y.) (01.09.2021)
Published in Neoplasia (New York, N.Y.) (01.09.2021)
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USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth
Gierisch, Maria E., Pedot, Gloria, Walser, Franziska, Lopez-Garcia, Laura A., Jaaks, Patricia, Niggli, Felix K., Schäfer, Beat W.
Published in Scientific reports (30.01.2019)
Published in Scientific reports (30.01.2019)
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Single cell transcriptomic profiling identifies tumor-acquired and therapy-resistant cell states in pediatric rhabdomyosarcoma
Danielli, Sara G., Wei, Yun, Dyer, Michael A., Stewart, Elizabeth, Sheppard, Heather, Wachtel, Marco, Schäfer, Beat W., Patel, Anand G., Langenau, David M.
Published in Nature communications (26.07.2024)
Published in Nature communications (26.07.2024)
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The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion
Jaaks, Patricia, D'Alessandro, Valentina, Grob, Nicole, Büel, Sina, Hajdin, Katarina, Schäfer, Beat W, Bernasconi, Michele
Published in PloS one (22.08.2016)
Published in PloS one (22.08.2016)
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Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue
Gierisch, Maria E., Pfistner, Franziska, Lopez-Garcia, Laura A., Harder, Lena, Schäfer, Beat W., Niggli, Felix K.
Published in The Journal of biological chemistry (23.12.2016)
Published in The Journal of biological chemistry (23.12.2016)
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Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization
Pedot, Gloria, Marques, Joana Graça, Ambühl, Philip P, Wachtel, Marco, Kasper, Stephanie, Ngo, Quy A, Niggli, Felix K, Schäfer, Beat W
Published in Neoplasia (New York, N.Y.) (01.05.2022)
Published in Neoplasia (New York, N.Y.) (01.05.2022)
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PAX3-FOXO1 uses its activation domain to recruit CBP/P300 and shape RNA Pol2 cluster distribution
Asante, Yaw, Benischke, Katharina, Osman, Issra, Ngo, Quy A., Wurth, Jakob, Laubscher, Dominik, Kim, Hyunmin, Udhayakumar, Bhavatharini, Khan, Md Imdadul H., Chin, Diana H., Porch, Jadon, Chakraborty, Maharshi, Sallari, Richard, Delattre, Olivier, Zaidi, Sakina, Morice, Sarah, Surdez, Didier, Danielli, Sara G., Schäfer, Beat W., Gryder, Berkley E., Wachtel, Marco
Published in Nature communications (15.12.2023)
Published in Nature communications (15.12.2023)
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Corrigendum to "Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization" [Neoplasia volume 27 (2022) pp. 100784/Number C]
Pedot, Gloria, Marques, Joana Graça, Ambühl, Philip P, Wachtel, Marco, Kasper, Stephanie, Ngo, Quy A, Niggli, Felix K, Schäfer, Beat W
Published in Neoplasia (New York, N.Y.) (01.09.2022)
Published in Neoplasia (New York, N.Y.) (01.09.2022)
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YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells
Bierbaumer, Lisa, Katschnig, Anna M., Radic-Sarikas, Branka, Kauer, Maximilian O., Petro, Jeffrey A., Högler, Sandra, Gurnhofer, Elisabeth, Pedot, Gloria, Schäfer, Beat W., Schwentner, Raphaela, Mühlbacher, Karin, Kromp, Florian, Aryee, Dave N. T., Kenner, Lukas, Uren, Aykut, Kovar, Heinrich
Published in Oncogenesis (New York, NY) (08.01.2021)
Published in Oncogenesis (New York, NY) (08.01.2021)
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Author Correction: CRISPR activation screen identifies TGFβ-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma
Saratov, Vadim, Ngo, Quy A., Pedot, Gloria, Sidorov, Semjon, Wachtel, Marco, Niggli, Felix K., Schäfer, Beat W.
Published in Scientific reports (02.08.2022)
Published in Scientific reports (02.08.2022)
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Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma
Boro, Aleksandar, Prêtre, Kathya, Rechfeld, Florian, Thalhammer, Verena, Oesch, Susanne, Wachtel, Marco, Schäfer, Beat W., Niggli, Felix K.
Published in International journal of cancer (01.11.2012)
Published in International journal of cancer (01.11.2012)
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Fenretinide Acts as Potent Radiosensitizer for Treatment of Rhabdomyosarcoma Cells
Brack, Eva, Bender, Sabine, Wachtel, Marco, Pruschy, Martin, Schäfer, Beat W.
Published in Frontiers in oncology (15.06.2021)
Published in Frontiers in oncology (15.06.2021)
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