Diffuse large B‐cell lymphoma cell‐cycle progression requires the cyclin‐G associated kinase (GAK), a novel drug target from machine learning‐enabled phenotypic screening
Lightfuss, O. B., Newsam, A., Kumar, P., Li, L., Ghoshal, A., Alaoui, A. Y., Schürer, S., Lemmon, V., Maura, F., Feng, Y., Ali, H. A, Schatz, J. H
Published in Hematological oncology (01.06.2023)
Published in Hematological oncology (01.06.2023)
Get full text
Journal Article
BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types
Howe, E A, de Souza, A, Lahr, D L, Chatwin, S, Montgomery, P, Alexander, B R, Nguyen, D-T, Cruz, Y, Stonich, D A, Walzer, G, Rose, J T, Picard, S C, Liu, Z, Rose, J N, Xiang, X, Asiedu, J, Durkin, D, Levine, J, Yang, J J, Schürer, S C, Braisted, J C, Southall, N, Southern, M R, Chung, T D Y, Brudz, S, Tanega, C, Schreiber, S L, Bittker, J A, Guha, R, Clemons, P A
Published in Nucleic acids research (28.01.2015)
Published in Nucleic acids research (28.01.2015)
Get full text
Journal Article
148 (PB136): UMF814A is a potent, selective and orally bioavailable STK17A inhibitor for MDS/AML
Bhalgat, A., Chaudhry, S., Schürer, S., Feng, Y., Taylor, J.
Published in European journal of cancer (1990) (01.10.2024)
Published in European journal of cancer (1990) (01.10.2024)
Get full text
Journal Article
Material influence on mechanical properties of gears with alternative microstructures
Blech, N., Güntner, C., Schurer, S., Steinbacher, M., Tobie, T., Stahl, K.
Published in Forschung im Ingenieurwesen (01.06.2023)
Published in Forschung im Ingenieurwesen (01.06.2023)
Get full text
Journal Article
241 (PB229): Critical role of cyclin-G associated kinase (GAK) in mitotic progression defines a new target for cancer therapy linked to deficiency of the RB tumor suppressor
Lightfuss, O., Kumar, P., Younes, P., Newsam, A., Manara, P., Alaoui, A., Schürer, S., Lemmon, V., Maura, F., Feng, Y., Ali, H., Schatz, J.
Published in European journal of cancer (1990) (01.10.2024)
Published in European journal of cancer (1990) (01.10.2024)
Get full text
Journal Article
Novel inhibitors of α4β1 integrin receptor interactions through library synthesis and screening
Souers, Andrew J, Virgilio, Alex A, Schürer, Stephan S, Ellman, Jonathan A, Kogan, Timothy P, West, Henry E, Ankener, Wendy, Vanderslice, Peter
Published in Bioorganic & medicinal chemistry letters (08.09.1998)
Published in Bioorganic & medicinal chemistry letters (08.09.1998)
Get full text
Journal Article
Unexplored therapeutic opportunities in the human genome
Oprea, Tudor I., Bologa, Cristian G., Brunak, Søren, Campbell, Allen, Gan, Gregory N., Gaulton, Anna, Gomez, Shawn M., Guha, Rajarshi, Hersey, Anne, Holmes, Jayme, Jadhav, Ajit, Jensen, Lars Juhl, Johnson, Gary L., Karlson, Anneli, Leach, Andrew R., Ma'ayan, Avi, Malovannaya, Anna, Mani, Subramani, Mathias, Stephen L., McManus, Michael T., Meehan, Terrence F., von Mering, Christian, Muthas, Daniel, Nguyen, Dac-Trung, Overington, John P., Papadatos, George, Qin, Jun, Reich, Christian, Roth, Bryan L., Schürer, Stephan C., Simeonov, Anton, Sklar, Larry A., Southall, Noel, Tomita, Susumu, Tudose, Ilinca, Ursu, Oleg, Vidović, Dušica, Waller, Anna, Westergaard, David, Yang, Jeremy J., Zahoránszky-Köhalmi, Gergely
Published in Nature reviews. Drug discovery (01.05.2018)
Published in Nature reviews. Drug discovery (01.05.2018)
Get full text
Journal Article
TCRD and Pharos 2021: mining the human proteome for disease biology
Sheils, Timothy K, Mathias, Stephen L, Kelleher, Keith J, Siramshetty, Vishal B, Nguyen, Dac-Trung, Bologa, Cristian G, Jensen, Lars Juhl, Vidović, Dušica, Koleti, Amar, Schürer, Stephan C, Waller, Anna, Yang, Jeremy J, Holmes, Jayme, Bocci, Giovanni, Southall, Noel, Dharkar, Poorva, Mathé, Ewy, Simeonov, Anton, Oprea, Tudor I
Published in Nucleic Acids Research (08.01.2021)
Published in Nucleic Acids Research (08.01.2021)
Get full text
Journal Article
Web Resource
Novel inhibitors of alpha 4 beta 1 integrin receptor interactions through library synthesis and screening
Souers, A J, Virgilio, A A, Schürer, S S, Ellman, J A, Kogan, T P, West, H E, Ankener, W, Vanderslice, P
Published in Bioorganic & medicinal chemistry letters (08.09.1998)
Published in Bioorganic & medicinal chemistry letters (08.09.1998)
Get full text
Journal Article
Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease
Maiguel, Dony, Faridi, Mohd Hafeez, Wei, Changli, Kuwano, Yoshihiro, Balla, Keir M, Hernandez, Dayami, Barth, Constantinos J, Lugo, Geanncarlo, Donnelly, Mary, Nayer, Ali, Moita, Luis F, Schürer, Stephan, Traver, David, Ruiz, Phillip, Vazquez-Padron, Roberto I, Ley, Klaus, Reiser, Jochen, Gupta, Vineet
Published in Science signaling (06.09.2011)
Published in Science signaling (06.09.2011)
Get more information
Journal Article
Towards affordable 3D physics-based river flow rating: application over the Luangwa River basin
Samboko, Hubert T, Schurer, Sten, Savenije, Hubert H. G, Makurira, Hodson, Banda, Kawawa, Winsemius, Hessel
Published in Geoscientific instrumentation, methods and data systems (21.08.2023)
Published in Geoscientific instrumentation, methods and data systems (21.08.2023)
Get full text
Journal Article
DD-01 LIGAND- AND STRUCTURE-BASED VIRTUAL SCREENING TO DISCOVER POLYPHARMACOLOGICAL DUAL EGFR AND BRD4 INHIBITORS
Allen, B., Mehta, S., Ayad, N., Schurer, S.
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)
Get full text
Journal Article
Novel inhibitors of α4β1 integrin receptor interactions through library synthesis and screening: Combinatorial chemistry
SOUERS, A. J, VIRGILIO, A. A, SCHÜRER, S. S, ELLMAN, J. A, KOGAN, T. P, WEST, H. E, ANKENER, W, VANDERSLICE, P
Published in Bioorganic & medicinal chemistry letters (1998)
Get full text
Published in Bioorganic & medicinal chemistry letters (1998)
Journal Article