Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity
Karpinski, Janet, Hauber, Ilona, Chemnitz, Jan, Schäfer, Carola, Paszkowski-Rogacz, Maciej, Chakraborty, Deboyoti, Beschorner, Niklas, Hofmann-Sieber, Helga, Lange, Ulrike C, Grundhoff, Adam, Hackmann, Karl, Schrock, Evelin, Abi-Ghanem, Josephine, Pisabarro, M Teresa, Surendranath, Vineeth, Schambach, Axel, Lindner, Christoph, van Lunzen, Jan, Hauber, Joachim, Buchholz, Frank
Published in Nature biotechnology (01.04.2016)
Published in Nature biotechnology (01.04.2016)
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Journal Article
Targeted HIV-1 Latency Reversal Using CRISPR/Cas9-Derived Transcriptional Activator Systems
Bialek, Julia K, Dunay, Gábor A, Voges, Maike, Schäfer, Carola, Spohn, Michael, Stucka, Rolf, Hauber, Joachim, Lange, Ulrike C
Published in PloS one (24.06.2016)
Published in PloS one (24.06.2016)
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Journal Article
Partial protection against P. vivax infection diminishes hypnozoite burden and blood-stage relapses
Schäfer, Carola, Dambrauskas, Nicholas, Reynolds, Laura M., Trakhimets, Olesya, Raappana, Andrew, Flannery, Erika L., Roobsoong, Wanlapa, Sattabongkot, Jetsumon, Mikolajczak, Sebastian A., Kappe, Stefan H.I., Sather, D. Noah
Published in Cell host & microbe (12.05.2021)
Published in Cell host & microbe (12.05.2021)
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Journal Article
A replication-competent late liver stage-attenuated human malaria parasite
Goswami, Debashree, Betz, William, Locham, Navin K, Parthiban, Chaitra, Brager, Carolyn, Schäfer, Carola, Camargo, Nelly, Nguyen, Thao, Kennedy, Spencer Y, Murphy, Sean C, Vaughan, Ashley M, Kappe, Stefan Hi
Published in JCI insight (09.07.2020)
Published in JCI insight (09.07.2020)
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Journal Article
Enhanced Functional Activity of the Cannabinoid Type-1 Receptor Mediates Adolescent Behavior
Schneider, Miriam, Kasanetz, Fernando, Lynch, Diane L, Friemel, Chris M, Lassalle, Olivier, Hurst, Dow P, Steindel, Frauke, Monory, Krisztina, Schäfer, Carola, Miederer, Isabelle, Leweke, F Markus, Schreckenberger, Mathias, Lutz, Beat, Reggio, Patricia H, Manzoni, Olivier J, Spanagel, Rainer
Published in The Journal of neuroscience (14.10.2015)
Published in The Journal of neuroscience (14.10.2015)
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Journal Article
Reduced Antimony Accumulation in ARM58-Overexpressing Leishmania infantum
SCHAFER, Carola, NEVADO, Paloma Tejera, ZANDER, Dorothea, CLOS, Joachim
Published in Antimicrobial Agents and Chemotherapy (01.03.2014)
Published in Antimicrobial Agents and Chemotherapy (01.03.2014)
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Journal Article
A Humanized Mouse Model for Plasmodium vivax to Test Interventions that Block Liver Stage to Blood Stage Transition and Blood Stage Infection
Schäfer, Carola, Roobsoong, Wanlapa, Kangwanrangsan, Niwat, Bardelli, Martino, Rawlinson, Thomas A., Dambrauskas, Nicholas, Trakhimets, Olesya, Parthiban, Chaitra, Goswami, Debashree, Reynolds, Laura M., Kennedy, Spencer Y., Flannery, Erika L., Murphy, Sean C., Sather, D. Noah, Draper, Simon J., Sattabongkot, Jetsumon, Mikolajczak, Sebastian A., Kappe, Stefan H.I.
Published in iScience (21.08.2020)
Published in iScience (21.08.2020)
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Journal Article
Plasmodium vivax latent liver infection is characterized by persistent hypnozoites, hypnozoite-derived schizonts, and time-dependent efficacy of primaquine
Flannery, Erika L., Kangwanrangsan, Niwat, Chuenchob, Vorada, Roobsoong, Wanlapa, Fishbaugher, Matthew, Zhou, Kevin, Billman, Zachary P., Martinson, Thomas, Olsen, Tayla M., Schäfer, Carola, Campo, Brice, Murphy, Sean C., Mikolajczak, Sebastian A., Kappe, Stefan H.I., Sattabongkot, Jetsumon
Published in Molecular therapy. Methods & clinical development (08.09.2022)
Published in Molecular therapy. Methods & clinical development (08.09.2022)
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Journal Article
O5 CRISPR/Cas9-derived activation systems as new tools for induction of latent human immunodeficiency virus (HIV)
Bialek, JuliaK, Voges, Maike, Dunay, Gabor A., Schäfer, Carola, Spohn, Michael, Hauber, Joachim, Lange, Ulrike C.
Published in Journal of Virus Eradication (01.09.2016)
Published in Journal of Virus Eradication (01.09.2016)
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Journal Article
Humanized Mouse Models for the Study of Human Malaria Parasite Biology, Pathogenesis, and Immunity
Minkah, Nana K, Schafer, Carola, Kappe, Stefan H I
Published in Frontiers in immunology (19.04.2018)
Published in Frontiers in immunology (19.04.2018)
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Journal Article
A recombinant antibody against Plasmodium vivax UIS4 for distinguishing replicating from dormant liver stages
Schafer, Carola, Dambrauskas, Nicholas, Steel, Ryan W, Carbonetti, Sara, Chuenchob, Vorada, Flannery, Erika L, Vigdorovich, Vladimir, Oliver, Brian G, Roobsoong, Wanlapa, Maher, Steven P, Kyle, Dennis, Sattabongkot, Jetsumon, Kappe, Stefan H I, Mikolajczak, Sebastian A, Sather, D Noah
Published in Malaria journal (17.10.2018)
Published in Malaria journal (17.10.2018)
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Journal Article
Plasmodium falciparum Liver Stage Infection and Transition to Stable Blood Stage Infection in Liver-Humanized and Blood-Humanized FRGN KO Mice Enables Testing of Blood Stage Inhibitory Antibodies (Reticulocyte-Binding Protein Homolog 5) In Vivo
Foquet, Lander, Schafer, Carola, Minkah, Nana K, Alanine, Daniel G W, Flannery, Erika L, Steel, Ryan W J, Sack, Brandon K, Camargo, Nelly, Fishbaugher, Matthew, Betz, Will, Nguyen, Thao, Billman, Zachary P, Wilson, Elizabeth M, Bial, John, Murphy, Sean C, Draper, Simon J, Mikolajczak, Sebastian A, Kappe, Stefan H I
Published in Frontiers in immunology (14.03.2018)
Published in Frontiers in immunology (14.03.2018)
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Journal Article
Kit Regulates HSC Engraftment across the Human-Mouse Species Barrier
Cosgun, Kadriye Nehir, Rahmig, Susann, Mende, Nicole, Reinke, Sören, Hauber, Ilona, Schäfer, Carola, Petzold, Anke, Weisbach, Henry, Heidkamp, Gordon, Purbojo, Ariawan, Cesnjevar, Robert, Platz, Alexander, Bornhäuser, Martin, Schmitz, Marc, Dudziak, Diana, Hauber, Joachim, Kirberg, Jörg, Waskow, Claudia
Published in Cell stem cell (07.08.2014)
Published in Cell stem cell (07.08.2014)
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Journal Article
Mass Spectrometry Identification of Biomarkers in Extracellular Vesicles From Plasmodium vivax Liver Hypnozoite Infections
Gualdrón-López, Melisa, Díaz-Varela, Miriam, Zanghi, Gigliola, Aparici-Herraiz, Iris, Steel, Ryan W.J., Schäfer, Carola, Cuscó, Pol, Chuenchob, Vorada, Kangwangransan, Niwat, Billman, Zachary P., Olsen, Tayla M., González, Juan R., Roobsoong, Wanlapa, Sattabongkot, Jetsumon, Murphy, Sean C., Mikolajczak, Sebastian A., Borràs, Eva, Sabidó, Eduard, Fernandez-Becerra, Carmen, Flannery, Erika L., Kappe, Stefan H.I., del Portillo, Hernando A.
Published in Molecular & cellular proteomics (01.10.2022)
Published in Molecular & cellular proteomics (01.10.2022)
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Journal Article
Assessing drug efficacy against Plasmodium falciparum liver stages in vivo
Flannery, Erika L, Foquet, Lander, Chuenchob, Vorada, Fishbaugher, Matthew, Billman, Zachary, Navarro, Mary Jane, Betz, William, Olsen, Tayla M, Lee, Joshua, Camargo, Nelly, Nguyen, Thao, Schafer, Carola, Sack, Brandon K, Wilson, Elizabeth M, Saunders, Jessica, Bial, John, Campo, Brice, Charman, Susan A, Murphy, Sean C, Phillips, Margaret A, Kappe, Stefan Hi, Mikolajczak, Sebastian A
Published in JCI insight (11.01.2018)
Published in JCI insight (11.01.2018)
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Journal Article
A novel marker, ARM58, confers antimony resistance to Leishmania spp
Nühs, Andrea, Schäfer, Carola, Zander, Dorothea, Trübe, Leona, Tejera Nevado, Paloma, Schmidt, Sonja, Arevalo, Jorge, Adaui, Vanessa, Maes, Louis, Dujardin, Jean-Claude, Clos, Joachim
Published in International journal for parasitology -- drugs and drug resistance (01.04.2014)
Published in International journal for parasitology -- drugs and drug resistance (01.04.2014)
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Journal Article
Next-generation LTR-specific Tre-recombinase targets a majority of HIV-1 isolates
Hauber, Joachim, Karpinski, Janet, Hauber, Ilona, Chemnitz, Jan, Hofmann-Sieber, Helga, Nagel, Claus-Henning, Beschorner, Niklas, Schäfer, Carola, Buchholz, Frank
Published in BMC infectious diseases (23.05.2014)
Published in BMC infectious diseases (23.05.2014)
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Journal Article