Search Results - "Scerni, Rosemary" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Novel benzofuran derivatives with dual 5-HT1A receptor and serotonin transporter affinity

Novel benzofuran derivatives with dual 5-HT1A receptor and serotonin transporter affinity

by Venkatesan, Aranapakam M, Dos Santos, O, Ellingboe, John, Evrard, Deborah A, Harrison, Boyd L, Smith, Deborah L, Scerni, Rosemary, Hornby, Geoffrey A, Schechter, Lee E, Andree, Terrence H
Published in Bioorganic & medicinal chemistry letters (01.02.2010)

Get full text

Journal Article

Studies toward the Discovery of the Next Generation of Antidepressants. 3. Dual 5-HT1A and Serotonin Transporter Affinity within a Class of N-Aryloxyethylindolylalkylamines

Studies toward the Discovery of the Next Generation of Antidepressants. 3. Dual 5-HT1A and Serotonin Transporter Affinity within a Class of N-Aryloxyethylindolylalkylamines

by Mewshaw, Richard E, Zhou, Dahui, Zhou, Ping, Shi, Xiaojie, Hornby, Geoffrey, Spangler, Taylor, Scerni, Rosemary, Smith, Deborah, Schechter, Lee E, Andree, Terrance H
Published in Journal of medicinal chemistry (15.07.2004)

Get full text

Journal Article

Studies toward the discovery of the next generation of antidepressants. Part 5 : 3,4-Dihydro-2H-benzo[1,4]oxazine derivatives with dual 5-HT1A receptor and serotonin transporter affinity

Studies toward the discovery of the next generation of antidepressants. Part 5 : 3,4-Dihydro-2H-benzo[1,4]oxazine derivatives with dual 5-HT1A receptor and serotonin transporter affinity

by DAHUI ZHOU, HARRISON, Boyd L, SHAH, Uresh, ANDREE, Terrance H, HOMBY, Geoffrey A, SCERNI, Rosemary, SCHECHTER, Lee E, SMITH, Deborah L, SULLIVAN, Kelly M, MEWSHAW, Richard E
Published in Bioorganic & medicinal chemistry letters (01.03.2006)

Get full text

Journal Article

Novel benzofuran derivatives with dual 5-HT sub(1A) receptor and serotonin transporter affinity

Novel benzofuran derivatives with dual 5-HT sub(1A) receptor and serotonin transporter affinity

by Venkatesan, Aranapakam M, Dos Santos, O, Ellingboe, John, Evrard, Deborah A, Harrison, Boyd L, Smith, Deborah L, Scerni, Rosemary, Hornby, Geoffrey A, Schechter, Lee E, Andree, Terrence H
Published in Bioorganic & medicinal chemistry letters (01.02.2010)

Get full text

Journal Article

Novel benzofuran derivatives with dual 5-HT 1A receptor and serotonin transporter affinity

Novel benzofuran derivatives with dual 5-HT 1A receptor and serotonin transporter affinity

by Venkatesan, Aranapakam M., Dos Santos, O., Ellingboe, John, Evrard, Deborah A., Harrison, Boyd L., Smith, Deborah L., Scerni, Rosemary, Hornby, Geoffrey A., Schechter, Lee E., Andree, Terrence H.
Published in Bioorganic & medicinal chemistry letters (2010)

Get full text

Journal Article

Synthesis and SAR of Adatanserin: Novel Adamantyl Aryl- and Heteroarylpiperazines with Dual Serotonin 5-HT1A and 5-HT2 Activity as Potential Anxiolytic and Antidepressant Agents

Synthesis and SAR of Adatanserin: Novel Adamantyl Aryl- and Heteroarylpiperazines with Dual Serotonin 5-HT1A and 5-HT2 Activity as Potential Anxiolytic and Antidepressant Agents

by Abou-Gharbia, Magid A, Childers, Wayne E, Fletcher, Horace, McGaughey, Georgia, Patel, Usha, Webb, Michael B, Yardley, John, Andree, Terrance, Boast, Carl, Kucharik, Robert J, Marquis, Karen, Morris, Herman, Scerni, Rosemary, Moyer, John A
Published in Journal of medicinal chemistry (16.12.1999)

Get full text

Journal Article

Studies toward the discovery of the next generation of antidepressants. Part 5: 3,4-Dihydro-2H-benzo[1,4]oxazine derivatives with dual 5-HT sub(1A) receptor and serotonin transporter affinity

Studies toward the discovery of the next generation of antidepressants. Part 5: 3,4-Dihydro-2H-benzo[1,4]oxazine derivatives with dual 5-HT sub(1A) receptor and serotonin transporter affinity

by Zhou, Dahui, Harrison, Boyd L, Shah, Uresh, Andree, Terrance H, Hornby, Geoffrey A, Scerni, Rosemary, Schechter, Lee E, Smith, Deborah L, Sullivan, Kelly M, Mewshaw, Richard E
Published in Bioorganic & medicinal chemistry letters (01.01.2006)

Get full text

Journal Article

Studies toward the discovery of the next generation of antidepressants. Part 5: 3,4-Dihydro-2 H-benzo[1,4]oxazine derivatives with dual 5-HT 1A receptor and serotonin transporter affinity

Studies toward the discovery of the next generation of antidepressants. Part 5: 3,4-Dihydro-2 H-benzo[1,4]oxazine derivatives with dual 5-HT 1A receptor and serotonin transporter affinity

by Zhou, Dahui, Harrison, Boyd L., Shah, Uresh, Andree, Terrance H., Hornby, Geoffrey A., Scerni, Rosemary, Schechter, Lee E., Smith, Deborah L., Sullivan, Kelly M., Mewshaw, Richard E.
Published in Bioorganic & medicinal chemistry letters (2006)

Get full text

Journal Article

Studies toward the discovery of the next generation of antidepressants. Part 2: Incorporating a 5-HT1A antagonist component into a class of serotonin reuptake inhibitors

Studies toward the discovery of the next generation of antidepressants. Part 2: Incorporating a 5-HT1A antagonist component into a class of serotonin reuptake inhibitors

by MEWSHAW, Richard E, MEAGHER, Kristin L, PING ZHOU, DAHUI ZHOU, XIAOJIE SHI, SCERNI, Rosemary, SMITH, Deborah, SCHECHTER, Lee E, ANDREE, Terrance H
Published in Bioorganic & medicinal chemistry letters (11.02.2002)

Get full text

Journal Article

Studies toward the Discovery of the Next Generation of Antidepressants. 3. Dual 5-HT 1A and Serotonin Transporter Affinity within a Class of N -Aryloxyethylindolylalkylamines

Studies toward the Discovery of the Next Generation of Antidepressants. 3. Dual 5-HT 1A and Serotonin Transporter Affinity within a Class of N -Aryloxyethylindolylalkylamines

by Mewshaw, Richard E., Zhou, Dahui, Zhou, Ping, Shi, Xiaojie, Hornby, Geoffrey, Spangler, Taylor, Scerni, Rosemary, Smith, Deborah, Schechter, Lee E., Andree, Terrance H.
Published in Journal of medicinal chemistry (01.07.2004)

Get full text

Journal Article

Modulation of selective serotonin reuptake inhibitor and 5-HT1A antagonist activity in 8-aza-bicyclo[3.2.1]octane derivatives of 2,3-dihydro-1,4-benzodioxane

Modulation of selective serotonin reuptake inhibitor and 5-HT1A antagonist activity in 8-aza-bicyclo[3.2.1]octane derivatives of 2,3-dihydro-1,4-benzodioxane

by GILBERT, Adam M, STACK, Gary P, NILAKANTAN, Ramaswamy, KODAH, Jason, TRAN, Megan, SCERNI, Rosemary, XIAOJIE SHI, SMITH, Deborah L, ANDREE, Terrance H
Published in Bioorganic & medicinal chemistry letters (19.01.2004)

Get full text

Journal Article

Novel aryloxy-8-azabicyclo[3.2.1]oct-3-enes with 5-ht transporter and 5-HT1A affinity

Novel aryloxy-8-azabicyclo[3.2.1]oct-3-enes with 5-ht transporter and 5-HT1A affinity

by GILBERT, Adam M, COLEMAN, Thomas, KODAH, Jason, MEWSHAW, Richard E, SCERNI, Rosemary, SCHECHTER, Lee E, SMITH, Deborah L, ANDREE, Terrance H
Published in Bioorganic & medicinal chemistry letters (01.11.2004)

Get full text

Journal Article

Studies towards the next generation of antidepressants. Part 1 : Indolylcyclohexylamines as potent serotonin reuptake inhibitors

Studies towards the next generation of antidepressants. Part 1 : Indolylcyclohexylamines as potent serotonin reuptake inhibitors

by MEAGHER, Kristin L, MEWSHAW, Richard E, ANDREE, Terrance H, EVRARD, Deborah A, PING ZHOU, SMITH, Deborah L, SCERNI, Rosemary, SPANGLER, Taylor, ABULHAWA, Susan, XIAOJIE SHI, SCHECHTER, Lee E
Published in Bioorganic & medicinal chemistry letters (23.07.2001)

Get full text

Journal Article

Modulation of selective serotonin reuptake inhibitor and 5-HT 1A antagonist activity in 8-aza-bicyclo[3.2.1]octane derivatives of 2,3-dihydro-1,4-benzodioxane

Modulation of selective serotonin reuptake inhibitor and 5-HT 1A antagonist activity in 8-aza-bicyclo[3.2.1]octane derivatives of 2,3-dihydro-1,4-benzodioxane

by Gilbert, Adam M., Stack, Gary P., Nilakantan, Ramaswamy, Kodah, Jason, Tran, Megan, Scerni, Rosemary, Shi, Xiaojie, Smith, Deborah L., Andree, Terrance H.
Published in Bioorganic & medicinal chemistry letters (2004)

Get full text

Journal Article

Studies toward the discovery of the next generation of antidepressants. Part 2: incorporating a 5-HT(1A) antagonist component into a class of serotonin reuptake inhibitors

Studies toward the discovery of the next generation of antidepressants. Part 2: incorporating a 5-HT(1A) antagonist component into a class of serotonin reuptake inhibitors

by Mewshaw, Richard E, Meagher, Kristin L, Zhou, Ping, Zhou, Dahui, Shi, Xiaojie, Scerni, Rosemary, Smith, Deborah, Schechter, Lee E, Andree, Terrance H
Published in Bioorganic & medicinal chemistry letters (11.02.2002)

Get full text

Journal Article

Studies toward the discovery of the next generation of antidepressants. Part 2: Incorporating a 5-HT 1A antagonist component into a class of serotonin reuptake inhibitors

Studies toward the discovery of the next generation of antidepressants. Part 2: Incorporating a 5-HT 1A antagonist component into a class of serotonin reuptake inhibitors

by Mewshaw, Richard E., Meagher, Kristin L., Zhou, Ping, Zhou, Dahui, Shi, Xiaojie, Scerni, Rosemary, Smith, Deborah, Schechter, Lee E., Andree, Terrance H.
Published in Bioorganic & medicinal chemistry letters (2002)

Get full text

Journal Article

New Generation Dopaminergic Agents. 1. Discovery of a Novel Scaffold Which Embraces the D2 Agonist Pharmacophore. Structure−Activity Relationships of a Series of 2-(Aminomethyl)chromans

New Generation Dopaminergic Agents. 1. Discovery of a Novel Scaffold Which Embraces the D2 Agonist Pharmacophore. Structure−Activity Relationships of a Series of 2-(Aminomethyl)chromans

by Mewshaw, Richard E, Kavanagh, Joseph, Stack, Gary, Marquis, Karen L, Shi, Xiaojie, Kagan, Michael Z, Webb, Michael B, Katz, Alan H, Park, Anna, Kang, Young H, Abou-Gharbia, Magid, Scerni, Rosemary, Wasik, Theodore, Cortes-Burgos, Luz, Spangler, Taylor, Brennan, Julie A, Piesla, Michael, Mazandarani, Hossein, Cockett, Mark I, Ochalski, Rafal, Coupet, Joseph, Andree, Terrance H
Published in Journal of medicinal chemistry (19.12.1997)

Get full text

Journal Article

New generation dopaminergic agents .1. Discovery of a novel scaffold which embraces the D-2 agonist pharmacophore. Structure-activity relationships of a series of 2-(aminomethyl)chromans

New generation dopaminergic agents .1. Discovery of a novel scaffold which embraces the D-2 agonist pharmacophore. Structure-activity relationships of a series of 2-(aminomethyl)chromans

by Mewshaw, RE, Kavanagh, J, Stack, G, Marquis, KL, Shi, XJ, Kagan, MZ, Webb, MB, Katz, AH, Park, A, Kang, YH, Abou-Gharbia, M, Scerni, R, Wasik, T, Cortes-Burgos, L, Spangler, T, Brennan, JA, Piesla, M, Mazandarani, H, Cockett, MI, Ochalski, R, Coupet, J, Andree, TH
Published in Journal of medicinal chemistry (19.12.1997)

Get full text

Journal Article

New generation dopaminergic agents. 6. Structure-activity relationship studies of a series of 4-(aminoethoxy)indole and 4-(aminoethoxy)indolone derivatives based on the newly discovered 3-hydroxyphenoxyethylamine D-2 template

New generation dopaminergic agents. 6. Structure-activity relationship studies of a series of 4-(aminoethoxy)indole and 4-(aminoethoxy)indolone derivatives based on the newly discovered 3-hydroxyphenoxyethylamine D-2 template

by Mewshaw, RE, Webb, MB, Marquis, KL, McGaughey, GB, Shi, XJ, Wasik, T, Scerni, R, Brennan, JA, Andree, TH
Published in Journal of medicinal chemistry (03.06.1999)

Get full text

Journal Article

New Generation Dopaminergic Agents. 6. Structure−Activity Relationship Studies of a Series of 4-(Aminoethoxy)indole and 4-(Aminoethoxy)indolone Derivatives Based on the Newly Discovered 3-Hydroxyphenoxyethylamine D2 Template

New Generation Dopaminergic Agents. 6. Structure−Activity Relationship Studies of a Series of 4-(Aminoethoxy)indole and 4-(Aminoethoxy)indolone Derivatives Based on the Newly Discovered 3-Hydroxyphenoxyethylamine D2 Template

by Mewshaw, Richard E, Webb, Michael B, Marquis, Karen L, McGaughey, Georgia B, Shi, Xiaojie, Wasik, Theodore, Scerni, Rosemary, Brennan, Julie A, Andree, Terrance H
Published in Journal of medicinal chemistry (03.06.1999)

Get full text

Journal Article