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Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease
Zanoni, Paolo, Khetarpal, Sumeet A., Larach, Daniel B., Hancock-Cerutti, William F., Millar, John S., Cuchel, Marina, DerOhannessian, Stephanie, Kontush, Anatol, Surendran, Praveen, Saleheen, Danish, Trompet, Stella, Jukema, J. Wouter, De Craen, Anton, Deloukas, Panos, Sattar, Naveed, Ford, Ian, Packard, Chris, Majumder, Abdullah al Shafi, Alam, Dewan S., Di Angelantonio, Emanuele, Abecasis, Goncalo, Chowdhury, Rajiv, Erdmann, Jeanette, Nordestgaard, Børge G., Nielsen, Sune F., Tybjærg-Hansen, Anne, Schmidt, Ruth Frikke, Kuulasmaa, Kari, Liu, Dajiang J., Perola, Markus, Blankenberg, Stefan, Salomaa, Veikko, Männistö, Satu, Amouyel, Philippe, Arveiler, Dominique, Ferrieres, Jean, Müller-Nurasyid, Martina, Ferrario, Marco, Kee, Frank, Willer, Cristen J., Samani, Nilesh, Schunkert, Heribert, Butterworth, Adam S., Howson, Joanna M. M., Peloso, Gina M., Stitziel, Nathan O., Danesh, John, Kathiresan, Sekar, Rader, Daniel J.
Published in Science (American Association for the Advancement of Science) (11.03.2016)
Published in Science (American Association for the Advancement of Science) (11.03.2016)
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Targeted reduction of cholesterol uptake in cholesterol-addicted lymphoma cells blocks turnover of oxidized lipids to cause ferroptosis
Rink, Jonathan S., Lin, Adam Yuh, McMahon, Kaylin M., Calvert, Andrea E., Yang, Shuo, Taxter, Tim, Moreira, Jonathan, Chadburn, Amy, Behdad, Amir, Karmali, Reem, Thaxton, C. Shad, Gordon, Leo I.
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
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A genetically humanized mouse model for hepatitis C virus infection
Dorner, Marcus, Horwitz, Joshua A., Robbins, Justin B., Barry, Walter T., Feng, Qian, Mu, Kathy, Jones, Christopher T., Schoggins, John W., Catanese, Maria Teresa, Burton, Dennis R., Law, Mansun, Rice, Charles M., Ploss, Alexander
Published in Nature (London) (08.06.2011)
Published in Nature (London) (08.06.2011)
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No evidence that carotenoid pigments boost either immune or antioxidant defenses in a songbird
Koch, Rebecca E., Kavazis, Andreas N., Hasselquist, Dennis, Hood, Wendy R., Zhang, Yufeng, Toomey, Matthew B., Hill, Geoffrey E.
Published in Nature communications (05.02.2018)
Published in Nature communications (05.02.2018)
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Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis
Scholz, Markus, Horn, Katrin, Pott, Janne, Gross, Arnd, Kleber, Marcus E., Delgado, Graciela E., Mishra, Pashupati Prasad, Kirsten, Holger, Gieger, Christian, Müller-Nurasyid, Martina, Tönjes, Anke, Kovacs, Peter, Lehtimäki, Terho, Raitakari, Olli, Kähönen, Mika, Gylling, Helena, Baber, Ronny, Isermann, Berend, Stumvoll, Michael, Loeffler, Markus, März, Winfried, Meitinger, Thomas, Peters, Annette, Thiery, Joachim, Teupser, Daniel, Ceglarek, Uta
Published in Nature communications (10.01.2022)
Published in Nature communications (10.01.2022)
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ISX is a retinoic acid-sensitive gatekeeper that controls intestinal β,β-carotene absorption and vitamin A production
Lobo, Glenn P, Hessel, Susanne, Eichinger, Anne, Noy, Noa, Moise, Alexander R, Wyss, Adrian, Palczewski, Krzysztof, von Lintig, Johannes
Published in The FASEB journal (01.06.2010)
Published in The FASEB journal (01.06.2010)
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Hepatic Scavenger Receptor Class B Type 1 Knockdown Reduces Atherosclerosis and Enhances the Antiatherosclerotic Effect of Brown Fat Activation in APOE3-Leiden.CETP Mice
Zhou, Enchen, Li, Zhuang, Nakashima, Hiroyuki, Liu, Cong, Ying, Zhixiong, Foks, Amanda C., Berbée, Jimmy F.P., van Dijk, Ko Willems, Rensen, Patrick C.N., Wang, Yanan
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2021)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2021)
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CETP, LIPC, and SCARB1 variants in individuals with extremely high high-density lipoprotein-cholesterol levels
Lee, Chan Joo, Park, Mun Su, Kim, Miso, Ann, Soo-jin, Lee, Jaeho, Park, Sungha, Kang, Seok-Min, Jang, Yangsoo, Lee, Ji Hyun, Lee, Sang-Hak
Published in Scientific reports (29.07.2019)
Published in Scientific reports (29.07.2019)
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MicroRNA-192 impairs adipocyte triglyceride storage
Mysore, Raghavendra, Zhou, You, Sädevirta, Sanja, Savolainen-Peltonen, Hanna, Nidhina Haridas, P.A., Soronen, Jarkko, Leivonen, Marja, Sarin, Antti-Pekka, Fischer-Posovszky, Pamela, Wabitsch, Martin, Yki-Järvinen, Hannele, Olkkonen, Vesa M.
Published in Biochimica et biophysica acta (01.04.2016)
Published in Biochimica et biophysica acta (01.04.2016)
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Human Plasma Levels of Vitamin E and Carotenoids Are Associated with Genetic Polymorphisms in Genes Involved in Lipid Metabolism
Borel, Patrick, Moussa, Myriam, Reboul, Emmanuelle, Lyan, Bernard, Defoort, Catherine, Vincent-Baudry, Stéphanie, Maillot, Matthieu, Gastaldi, Marguerite, Darmon, Michel, Portugal, Henri, Planells, Richard, Lairon, Denis
Published in The Journal of nutrition (01.12.2007)
Published in The Journal of nutrition (01.12.2007)
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Effect of Bariatric Surgery-Induced Weight Loss on SR-BI-, ABCG1-, and ABCA1-Mediated Cellular Cholesterol Efflux in Obese Women
Aron-Wisnewsky, Judith, Julia, Zélie, Poitou, Christine, Bouillot, Jean-Luc, Basdevant, Arnaud, Chapman, M. John, Clement, Karine, Guerin, Maryse
Published in The journal of clinical endocrinology and metabolism (01.04.2011)
Published in The journal of clinical endocrinology and metabolism (01.04.2011)
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Adiponectin increases macrophages cholesterol efflux and suppresses foam cell formation in patients with type 2 diabetes mellitus
Wang, Min, Wang, Duan, Zhang, Yuhua, Wang, Xiaoming, Liu, Yan, Xia, Min
Published in Atherosclerosis (01.07.2013)
Published in Atherosclerosis (01.07.2013)
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Plasma-Advanced Oxidation Protein Products Are Potent High-Density Lipoprotein Receptor Antagonists In Vivo
Marsche, Gunther, Frank, Sasa, Hrzenjak, Andelko, Holzer, Michael, Dirnberger, Sabine, Wadsack, Christian, Scharnagl, Hubert, Stojakovic, Tatjana, Heinemann, Akos, Oettl, Karl
Published in Circulation research (27.03.2009)
Published in Circulation research (27.03.2009)
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Investigation of Genetic Variation in Scavenger Receptor Class B, Member 1 (SCARB1) and Association with Serum Carotenoids
McKay, Gareth J., Loane, Edward, Nolan, John M., Patterson, Christopher C., Meyers, Kristin J., Mares, Julie A., Yonova-Doing, Ekaterina, Hammond, Christopher J., Beatty, Stephen, Silvestri, Giuliana
Published in Ophthalmology (Rochester, Minn.) (01.08.2013)
Published in Ophthalmology (Rochester, Minn.) (01.08.2013)
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