Modeling NaV1.1/SCN1A sodium channel mutations in a microcircuit with realistic ion concentration dynamics suggests differential GABAergic mechanisms leading to hyperexcitability in epilepsy and hemiplegic migraine
Lemaire, Louisiane, Desroches, Mathieu, Krupa, Martin, Pizzamiglio, Lara, Scalmani, Paolo, Mantegazza, Massimo
Published in PLoS computational biology (01.07.2021)
Published in PLoS computational biology (01.07.2021)
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Action potential initiation in neocortical inhibitory interneurons
Li, Tun, Tian, Cuiping, Scalmani, Paolo, Frassoni, Carolina, Mantegazza, Massimo, Wang, Yonghong, Yang, Mingpo, Wu, Si, Shu, Yousheng
Published in PLoS biology (01.09.2014)
Published in PLoS biology (01.09.2014)
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Ligand-gated mechanisms leading to ictogenesis in focal epileptic disorders
Avoli, Massimo, Chen, Li-Yuan, Di Cristo, Graziella, Librizzi, Laura, Scalmani, Paolo, Shiri, Zahra, Uva, Laura, de Curtis, Marco, Lévesque, Maxime
Published in Neurobiology of disease (01.05.2023)
Published in Neurobiology of disease (01.05.2023)
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Histone Deacetylase Inhibitors Ameliorate Morphological Defects and Hypoexcitability of iPSC-Neurons from Rubinstein-Taybi Patients
Alari, Valentina, Scalmani, Paolo, Ajmone, Paola Francesca, Perego, Sara, Avignone, Sabrina, Catusi, Ilaria, Lonati, Paola Adele, Borghi, Maria Orietta, Finelli, Palma, Terragni, Benedetta, Mantegazza, Massimo, Russo, Silvia, Larizza, Lidia
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Published in International journal of molecular sciences (28.05.2021)
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Rescuing epileptic and behavioral alterations in a Dravet syndrome mouse model by inhibiting eukaryotic elongation factor 2 kinase (eEF2K)
Beretta, Stefania, Gritti, Laura, Ponzoni, Luisa, Scalmani, Paolo, Mantegazza, Massimo, Sala, Mariaelvina, Verpelli, Chiara, Sala, Carlo
Published in Molecular autism (03.01.2022)
Published in Molecular autism (03.01.2022)
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Effects in Neocortical Neurons of Mutations of the Nav1.2 Na+ Channel causing Benign Familial Neonatal-Infantile Seizures
Scalmani, Paolo, Rusconi, Raffaella, Armatura, Elena, Zara, Federico, Avanzini, Giuliano, Franceschetti, Silvana, Mantegazza, Massimo
Published in The Journal of neuroscience (04.10.2006)
Published in The Journal of neuroscience (04.10.2006)
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Modulatory Proteins Can Rescue a Trafficking Defective Epileptogenic Nav1.1 Na+ Channel Mutant
Rusconi, Raffaella, Scalmani, Paolo, Cassulini, Rita Restano, Giunti, Giulia, Gambardella, Antonio, Franceschetti, Silvana, Annesi, Grazia, Wanke, Enzo, Mantegazza, Massimo
Published in The Journal of neuroscience (10.10.2007)
Published in The Journal of neuroscience (10.10.2007)
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Involvement of GABAergic Interneuron Subtypes in 4-Aminopyridine-Induced Seizure-Like Events in Mouse Entorhinal Cortex in Vitro
Scalmani, Paolo, Paterra, Rosina, Mantegazza, Massimo, Avoli, Massimo, de Curtis, Marco
Published in The Journal of neuroscience (15.03.2023)
Published in The Journal of neuroscience (15.03.2023)
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Interneuronal Network Activity at the Onset of Seizure-Like Events in Entorhinal Cortex Slices
Librizzi, Laura, Losi, Gabriele, Marcon, Iacopo, Sessolo, Michele, Scalmani, Paolo, Carmignoto, Giorgio, de Curtis, Marco
Published in The Journal of neuroscience (25.10.2017)
Published in The Journal of neuroscience (25.10.2017)
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Initiation of migraine-related cortical spreading depolarization by hyperactivity of GABAergic neurons and NaV1.1 channels
Chever, Oana, Zerimech, Sarah, Scalmani, Paolo, Lemaire, Louisiane, Pizzamiglio, Lara, Loucif, Alexandre, Ayrault, Marion, Krupa, Martin, Desroches, Mathieu, Duprat, Fabrice, Léna, Isabelle, Cestèle, Sandrine, Mantegazza, Massimo
Published in The Journal of clinical investigation (01.11.2021)
Published in The Journal of clinical investigation (01.11.2021)
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Cholinergic modulation inhibits cortical spreading depression in mouse neocortex through activation of muscarinic receptors and decreased excitatory/inhibitory drive
Zerimech, Sarah, Chever, Oana, Scalmani, Paolo, Pizzamiglio, Lara, Duprat, Fabrice, Mantegazza, Massimo
Published in Neuropharmacology (01.04.2020)
Published in Neuropharmacology (01.04.2020)
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SULT4A1 Modulates Synaptic Development and Function by Promoting the Formation of PSD-95/NMDAR Complex
Culotta, Lorenza, Scalmani, Paolo, Vinci, Ersilia, Terragni, Benedetta, Sessa, Alessandro, Broccoli, Vania, Mantegazza, Massimo, Boeckers, Tobias, Verpelli, Chiara
Published in The Journal of neuroscience (09.09.2020)
Published in The Journal of neuroscience (09.09.2020)
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Ranolazine vs phenytoin: greater effect of ranolazine on the transient Na+ current than on the persistent Na+ current in central neurons
Terragni, Benedetta, Scalmani, Paolo, Colombo, Elisa, Franceschetti, Silvana, Mantegazza, Massimo
Published in Neuropharmacology (01.11.2016)
Published in Neuropharmacology (01.11.2016)
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Modeling Na.sub.V1.1/SCN1A sodium channel mutations in a microcircuit with realistic ion concentration dynamics suggests differential GABAergic mechanisms leading to hyperexcitability in epilepsy and hemiplegic migraine
Lemaire, Louisiane, Desroches, Mathieu, Krupa, Martin, Pizzamiglio, Lara, Scalmani, Paolo, Mantegazza, Massimo
Published in PLoS computational biology (27.07.2021)
Published in PLoS computational biology (27.07.2021)
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Post-translational dysfunctions in channelopathies of the nervous system
Terragni, Benedetta, Scalmani, Paolo, Franceschetti, Silvana, Cestèle, Sandrine, Mantegazza, Massimo
Published in Neuropharmacology (01.04.2018)
Published in Neuropharmacology (01.04.2018)
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Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice
Vicidomini, C, Ponzoni, L, Lim, D, Schmeisser, M J, Reim, D, Morello, N, Orellana, D, Tozzi, A, Durante, V, Scalmani, P, Mantegazza, M, Genazzani, A A, Giustetto, M, Sala, M, Calabresi, P, Boeckers, T M, Sala, C, Verpelli, C
Published in Molecular psychiatry (01.05.2017)
Published in Molecular psychiatry (01.05.2017)
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Initiation of migraine-related cortical spreading depolarization by hyperactivity of GABAergic neurons and [Na.sub.v]1.1 channels
Chever, Oana, Zerimech, Sarah, Scalmani, Paolo, Lemaire, Louisiane, Pizzamiglio, Lara, Loucif, Alexandre, Ayrault, Marion, Krupa, Martin, Desroches, Mathieu, Duprat, Fabrice, Lena, Isabelle, Cestele, Sandrine, Mantegazza, Massimo
Published in The Journal of clinical investigation (01.11.2021)
Published in The Journal of clinical investigation (01.11.2021)
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