Low-dose self-amplifying mRNA COVID-19 vaccine drives strong protective immunity in non-human primates against SARS-CoV-2 infection
Rappaport, Amy R, Hong, Sue-Jean, Scallan, Ciaran D, Gitlin, Leonid, Akoopie, Arvin, Boucher, Gregory R, Egorova, Milana, Espinosa, J Aaron, Fidanza, Mario, Kachura, Melissa A, Shen, Annie, Sivko, Gloria, Van Abbema, Anne, Veres, Robert L, Jooss, Karin
Published in Nature communications (07.06.2022)
Published in Nature communications (07.06.2022)
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GRT-R910: a self-amplifying mRNA SARS-CoV-2 vaccine boosts immunity for ≥6 months in previously-vaccinated older adults
Palmer, Christine D, Scallan, Ciaran D, Kraemer Tardif, Lauren D, Kachura, Melissa A, Rappaport, Amy R, Koralek, Daniel O, Uriel, Alison, Gitlin, Leonid, Klein, Joshua, Davis, Matthew J, Venkatraman, Harshni, Hart, Meghan G, Jaroslavsky, Jason R, Kounlavouth, Sonia, Marrali, Martina, Nganje, Charmaine N, Bae, Kyounghwa, Yan, Tiffany, Leodones, Katharyn, Egorova, Milana, Hong, Sue-Jean, Kuan, Jenchun, Grappi, Silvia, Garbes, Pedro, Jooss, Karin, Ustianowski, Andrew
Published in Nature communications (06.06.2023)
Published in Nature communications (06.06.2023)
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Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy
Jiang, Haiyan, Couto, Linda B., Patarroyo-White, Susannah, Liu, Tongyao, Nagy, Dea, Vargas, Joseph A., Zhou, Shangzhen, Scallan, Ciaran D., Sommer, Jurg, Vijay, Sharmila, Mingozzi, Federico, High, Katherine A., Pierce, Glenn F.
Published in Blood (15.11.2006)
Published in Blood (15.11.2006)
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An Adenovirus-Based Vaccine with a Double-Stranded RNA Adjuvant Protects Mice and Ferrets against H5N1 Avian Influenza in Oral Delivery Models
Scallan, Ciaran D, Tingley, Debora W, Lindbloom, Jonathan D, Toomey, James S, Tucker, Sean N
Published in Clinical and Vaccine Immunology (01.01.2013)
Published in Clinical and Vaccine Immunology (01.01.2013)
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Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice
Scallan, Ciaran D., Jiang, Haiyan, Liu, Tongyao, Patarroyo-White, Susannah, Sommer, Jurg M., Zhou, Shangzhen, Couto, Linda B., Pierce, Glenn F.
Published in Blood (01.03.2006)
Published in Blood (01.03.2006)
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Multiyear therapeutic benefit of AAV serotypes 2, 6, and 8 delivering factor VIII to hemophilia A mice and dogs
Jiang, Haiyan, Lillicrap, David, Patarroyo-White, Susannah, Liu, Tongyao, Qian, Xiaobing, Scallan, Ciaran D., Powell, Sandra, Keller, Tracey, McMurray, Morag, Labelle, Andrea, Nagy, Dea, Vargas, Joseph A., Zhou, Shangzhen, Couto, Linda B., Pierce, Glenn F.
Published in Blood (01.07.2006)
Published in Blood (01.07.2006)
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Orally administered adenoviral-based vaccine induces respiratory mucosal memory and protection against RSV infection in cotton rats
Joyce, Christina, Scallan, Ciaran D., Mateo, Roberto, Belshe, Robert B., Tucker, Sean N., Moore, Anne C.
Published in Vaccine (05.07.2018)
Published in Vaccine (05.07.2018)
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A shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results
Rappaport, Amy R, Kyi, Chrisann, Lane, Monica, Hart, Meghan G, Johnson, Melissa L, Henick, Brian S, Liao, Chih-Yi, Mahipal, Amit, Shergill, Ardaman, Spira, Alexander I, Goldman, Jonathan W, Scallan, Ciaran D, Schenk, Desiree, Palmer, Christine D, Davis, Matthew J, Kounlavouth, Sonia, Kemp, Lindsey, Yang, Aaron, Li, Yaojun John, Likes, Molly, Shen, Annie, Boucher, Gregory R, Egorova, Milana, Veres, Robert L, Espinosa, J Aaron, Jaroslavsky, Jason R, Kraemer Tardif, Lauren D, Acrebuche, Lindsey, Puccia, Christopher, Sousa, Leiliane, Zhou, Rita, Bae, Kyounghwa, Hecht, J Randolph, Carbone, David P, Johnson, Benny, Allen, Andrew, Ferguson, Andrew R, Jooss, Karin
Published in Nature medicine (01.04.2024)
Published in Nature medicine (01.04.2024)
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Oral administration of an adenovirus vector encoding both an avian influenza A hemagglutinin and a TLR3 ligand induces antigen specific granzyme B and IFN-γ T cell responses in humans
Peters, Wendy, Brandl, Jennifer R, Lindbloom, Jonathan D, Martinez, C. Josefina, Scallan, Ciaran D, Trager, George R, Tingley, Debora W, Kabongo, Martin L, Tucker, Sean N
Published in Vaccine (25.03.2013)
Published in Vaccine (25.03.2013)
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Milk fat globule glycoproteins in human milk and in gastric aspirates of mother's milk-fed preterm infants
PETERSON, J. A, HAMOSH, M, SCALLAN, C. D, CERIANI, R. L, HENDERSON, T. R, MEHTA, N. R, ARMAND, M, HAMOSH, P
Published in Pediatric research (01.10.1998)
Published in Pediatric research (01.10.1998)
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Oral Modeling of an Adenovirus-Based Quadrivalent Influenza Vaccine in Ferrets and Mice
Scallan, Ciaran D., Lindbloom, Jonathan D., Tucker, Sean N.
Published in Infectious diseases and therapy (01.06.2016)
Published in Infectious diseases and therapy (01.06.2016)
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Oral adenoviral-based vaccines: historical perspective and future opportunity
Tucker, Sean N, Tingley, Debora W, Scallan, Ciaran D
Published in Expert review of vaccines (01.02.2008)
Published in Expert review of vaccines (01.02.2008)
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Sustained phenotypic correction of canine hemophilia A using an adeno-associated viral vector
Scallan, Ciaran D., Lillicrap, David, Jiang, Haiyan, Qian, Xiaobing, Patarroyo-White, Susannah L., Parker, Amy E., Liu, Tongyao, Vargas, Joseph, Nagy, Dea, Powell, Sharon K., Wright, J. Fraser, Turner, Patricia V., Tinlin, Shawn J., Webster, Sandra E., McClelland, Alan, Couto, Linda B.
Published in Blood (15.09.2003)
Published in Blood (15.09.2003)
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Phenotypic correction of a mouse model of hemophilia A using AAV2 vectors encoding the heavy and light chains of FVIII
Scallan, Ciaran D., Liu, Tongyao, Parker, Amy E., Patarroyo-White, Susannah L., Chen, Haifeng, Jiang, Haiyan, Vargas, Joseph, Nagy, Dea, Powell, Sharon K., Wright, J. Fraser, Sarkar, Rita, Kazazian, Haig H., McClelland, Alan, Couto, Linda B.
Published in Blood (01.12.2003)
Published in Blood (01.12.2003)
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Lactadherin (formerly BA46), a membrane-associated glycoprotein expressed in human milk and breast carcinomas, promotes Arg-Gly-Asp (RGD)-dependent cell adhesion
Taylor, M R, Couto, J R, Scallan, C D, Ceriani, R L, Peterson, J A
Published in DNA and cell biology (01.07.1997)
Published in DNA and cell biology (01.07.1997)
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Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results
Palmer, Christine D., Rappaport, Amy R., Davis, Matthew J., Hart, Meghan G., Scallan, Ciaran D., Hong, Sue-Jean, Gitlin, Leonid, Kraemer, Lauren D., Kounlavouth, Sonia, Yang, Aaron, Smith, Lindsey, Schenk, Desiree, Skoberne, Mojca, Taquechel, Kiara, Marrali, Martina, Jaroslavsky, Jason R., Nganje, Charmaine N., Maloney, Elizabeth, Zhou, Rita, Navarro-Gomez, Daniel, Greene, Adrienne C., Grotenbreg, Gijsbert, Greer, Renee, Blair, Wade, Cao, Minh Duc, Chan, Shawn, Bae, Kyounghwa, Spira, Alexander I., Roychowdhury, Sameek, Carbone, David P., Henick, Brian S., Drake, Charles G., Solomon, Benjamin J., Ahn, Daniel H., Mahipal, Amit, Maron, Steve B., Johnson, Benny, Rousseau, Raphael, Yelensky, Roman, Liao, Chih-Yi, Catenacci, Daniel V. T., Allen, Andrew, Ferguson, Andrew R., Jooss, Karin
Published in Nature medicine (01.08.2022)
Published in Nature medicine (01.08.2022)
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Abstract 3578: Optimization of shared neoantigen vaccine design to increase vaccine potency: From bench to bedside and back
Rappaport, Amy R., Palmer, Christine D., Shen, Annie, Dominguez, Claudia X., Hart, Meghan G., Kraemer, Lauren D., Koulavouth, Sonia, Marrali, Martina, Jaroslavsky, Jason R., Nganje, Charmaine N., Scallan, Ciaran D., Hong, Sue-Jean, Gitlin, Leonid, Lane, Monica, Catenacci, Daniel V., Kyi, Chrisann, Carbone, David P., Borghaei, Hossein, Rousseau, Raphael, Ferguson, Andrew, Jooss, Karin
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract 4159: Lower doses of self-amplifying mRNA drive superior neoantigen-specific CD8 T cell responses in cancer patients versus high doses
Palmer, Christine D., Rappaport, Amy R., Hart, Meghan G., Kraemer, Lauren D., Kounlavouth, Sonia, Marrali, Martina, Jaroslavsky, Jason R., Nganje, Charmaine N., Shen, Annie, Boucher, Gregory R., Kachura, Melissa A., Scallan, Ciaran D., Hong, Sue-Jean, Gitlin, Leonid, Spira, Alexander I., Kyi, Chrisann, Catenacci, Daniel V., Rousseau, Raphael, Ferguson, Andrew, Jooss, Karin
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Role of human-milk lactadherin in protectoin against symptomatic rotavirus infection
Newburg, David S, Peterson, Jerry A, Ruiz-Palacios, Guillermo M, Matson, David O, Morrow, Ardythe L, Shults, Justine, Guerrero, Maria de Lourdes, Chaturvedi, Prasoon, Newburg, Seth O, Scallan, Ciaran D, Taylor, Michael R, Ceriani, Robert L, Pickering, Larry K
Published in The Lancet (British edition) (01.04.1998)
Published in The Lancet (British edition) (01.04.1998)
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