Loading…
Loading…
Loading…
Loading…
Loading…
Hematopoietic Stem Cell Niche in Health and Disease
Hoggatt, Jonathan, Kfoury, Youmna, Scadden, David T
Published in Annual review of pathology (23.05.2016)
Published in Annual review of pathology (23.05.2016)
Get more information
Journal Article
Loading…
A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia
Baryawno, Ninib, Przybylski, Dariusz, Kowalczyk, Monika S., Kfoury, Youmna, Severe, Nicolas, Gustafsson, Karin, Kokkaliaris, Konstantinos D., Mercier, Francois, Tabaka, Marcin, Hofree, Matan, Dionne, Danielle, Papazian, Ani, Lee, Dongjun, Ashenberg, Orr, Subramanian, Ayshwarya, Vaishnav, Eeshit Dhaval, Rozenblatt-Rosen, Orit, Regev, Aviv, Scadden, David T.
Published in Cell (13.06.2019)
Published in Cell (13.06.2019)
Get full text
Journal Article
Loading…
Cell-State-Specific Metabolic Dependency in Hematopoiesis and Leukemogenesis
Wang, Ying-Hua, Israelsen, William J., Lee, Dongjun, Yu, Vionnie W.C., Jeanson, Nathaniel T., Clish, Clary B., Cantley, Lewis C., Vander Heiden, Matthew G., Scadden, David T.
Published in Cell (11.09.2014)
Published in Cell (11.09.2014)
Get full text
Journal Article
Loading…
The bone marrow at the crossroads of blood and immunity
Mercier, Francois E., Ragu, Christine, Scadden, David T.
Published in Nature reviews. Immunology (01.01.2012)
Published in Nature reviews. Immunology (01.01.2012)
Get full text
Journal Article
Loading…
Loading…
SIRT3 Reverses Aging-Associated Degeneration
Brown, Katharine, Xie, Stephanie, Qiu, Xiaolei, Mohrin, Mary, Shin, Jiyung, Liu, Yufei, Zhang, Dan, Scadden, David T., Chen, Danica
Published in Cell reports (Cambridge) (21.02.2013)
Published in Cell reports (Cambridge) (21.02.2013)
Get full text
Journal Article
Loading…
Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration
Park, Dongsu, Spencer, Joel A., Koh, Bong Ihn, Kobayashi, Tatsuya, Fujisaki, Joji, Clemens, Thomas L., Lin, Charles P., Kronenberg, Henry M., Scadden, David T.
Published in Cell stem cell (02.03.2012)
Published in Cell stem cell (02.03.2012)
Get full text
Journal Article
Loading…
Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis
Demers, Mélanie, Krause, Daniela S, Schatzberg, Daphne, Martinod, Kimberly, Voorhees, Jaymie R, Fuchs, Tobias A, Scadden, David T, Wagner, Denisa D
Published in Proceedings of the National Academy of Sciences - PNAS (07.08.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (07.08.2012)
Get full text
Journal Article
Loading…
Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment
Kfoury, Youmna, Baryawno, Ninib, Severe, Nicolas, Mei, Shenglin, Gustafsson, Karin, Hirz, Taghreed, Brouse, Thomas, Scadden, Elizabeth W., Igolkina, Anna A., Kokkaliaris, Konstantinos, Choi, Bryan D., Barkas, Nikolas, Randolph, Mark A., Shin, John H., Saylor, Philip J., Scadden, David T., Sykes, David B., Kharchenko, Peter V.
Published in Cancer cell (08.11.2021)
Published in Cancer cell (08.11.2021)
Get full text
Journal Article
Loading…
Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses
Hirz, Taghreed, Mei, Shenglin, Sarkar, Hirak, Kfoury, Youmna, Wu, Shulin, Verhoeven, Bronte M., Subtelny, Alexander O., Zlatev, Dimitar V., Wszolek, Matthew W., Salari, Keyan, Murray, Evan, Chen, Fei, Macosko, Evan Z., Wu, Chin-Lee, Scadden, David T., Dahl, Douglas M., Baryawno, Ninib, Saylor, Philip J., Kharchenko, Peter V., Sykes, David B.
Published in Nature communications (07.02.2023)
Published in Nature communications (07.02.2023)
Get full text
Journal Article
Loading…
dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments
Petukhov, Viktor, Guo, Jimin, Baryawno, Ninib, Severe, Nicolas, Scadden, David T., Samsonova, Maria G., Kharchenko, Peter V.
Published in Genome Biology (19.06.2018)
Published in Genome Biology (19.06.2018)
Get full text
Journal Article
Loading…
Direct measurement of local oxygen concentration in the bone marrow of live animals
Spencer, Joel A., Ferraro, Francesca, Roussakis, Emmanuel, Klein, Alyssa, Wu, Juwell, Runnels, Judith M., Zaher, Walid, Mortensen, Luke J., Alt, Clemens, Turcotte, Raphaël, Yusuf, Rushdia, Côté, Daniel, Vinogradov, Sergei A., Scadden, David T., Lin, Charles P.
Published in Nature (London) (10.04.2014)
Published in Nature (London) (10.04.2014)
Get full text
Journal Article
Loading…
Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment
Dong, Lei, Yu, Wen-Mei, Zheng, Hong, Loh, Mignon L., Bunting, Silvia T., Pauly, Melinda, Huang, Gang, Zhou, Muxiang, Broxmeyer, Hal E., Scadden, David T., Qu, Cheng-Kui
Published in Nature (London) (10.11.2016)
Published in Nature (London) (10.11.2016)
Get full text
Journal Article
Loading…
Programmable microencapsulation for enhanced mesenchymal stem cell persistence and immunomodulation
Mao, Angelo S., Özkale, Berna, Shah, Nisarg J., Vining, Kyle H., Descombes, Tiphaine, Zhang, Liyuan, Tringides, Christina M., Wong, Sing-Wan, Shin, Jae-Won, Scadden, David T., Weitz, David A., Mooney, David J.
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (30.07.2019)
Get full text
Journal Article
Loading…
Distinct bone marrow blood vessels differentially regulate haematopoiesis
Itkin, Tomer, Gur-Cohen, Shiri, Spencer, Joel A., Schajnovitz, Amir, Ramasamy, Saravana K., Kusumbe, Anjali P., Ledergor, Guy, Jung, Yookyung, Milo, Idan, Poulos, Michael G., Kalinkovich, Alexander, Ludin, Aya, Golan, Karin, Khatib, Eman, Kumari, Anju, Kollet, Orit, Shakhar, Guy, Butler, Jason M., Rafii, Shahin, Adams, Ralf H., Scadden, David T., Lin, Charles P., Lapidot, Tsvee
Published in Nature (London) (21.04.2016)
Published in Nature (London) (21.04.2016)
Get full text
Journal Article
Loading…
Angiogenin Promotes Hematopoietic Regeneration by Dichotomously Regulating Quiescence of Stem and Progenitor Cells
Goncalves, Kevin A., Silberstein, Lev, Li, Shuping, Severe, Nicolas, Hu, Miaofen G., Yang, Hailing, Scadden, David T., Hu, Guo-fu
Published in Cell (11.08.2016)
Published in Cell (11.08.2016)
Get full text
Journal Article