Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation
Nagase, Reina, Inoue, Daichi, Pastore, Alessandro, Fujino, Takeshi, Hou, Hsin-An, Yamasaki, Norimasa, Goyama, Susumu, Saika, Makoto, Kanai, Akinori, Sera, Yasuyuki, Horikawa, Sayuri, Ota, Yasunori, Asada, Shuhei, Hayashi, Yasutaka, Kawabata, Kimihito Cojin, Takeda, Reina, Tien, Hwei-Fang, Honda, Hiroaki, Abdel-Wahab, Omar, Kitamura, Toshio
Published in The Journal of experimental medicine (04.06.2018)
Published in The Journal of experimental medicine (04.06.2018)
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Journal Article
Novel working hypothesis for pathogenesis of hematological malignancies: combination of mutations-induced cellular phenotypes determines the disease (cMIP-DD)
Kitamura, Toshio, Watanabe-Okochi, Naoko, Enomoto, Yutaka, Nakahara, Fumio, Oki, Toshihiko, Komeno, Yukiko, Kato, Naoko, Doki, Noriko, Uchida, Tomoyuki, Kagiyama, Yuki, Togami, Katsuhiro, Kawabata, Kimihito C, Nishimura, Koutarou, Hayashi, Yasutaka, Nagase, Reina, Saika, Makoto, Fukushima, Tsuyoshi, Asada, Shuhei, Fujino, Takeshi, Izawa, Yuto, Horikawa, Sayuri, Fukuyama, Tomofusa, Tanaka, Yosuke, Ono, Ryoichi, Goyama, Susumu, Nosaka, Tetsuya, Kitaura, Jiro, Inoue, Daichi
Published in Journal of biochemistry (Tokyo) (01.01.2016)
Published in Journal of biochemistry (Tokyo) (01.01.2016)
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Journal Article
The molecular basis of myeloid malignancies
KITAMURA, Toshio, INOUE, Daichi, OKOCHI-WATANABE, Naoko, KATO, Naoko, KOMENO, Yukiko, LU, Yang, ENOMOTO, Yutaka, DOKI, Noriko, UCHIDA, Tomoyuki, KAGIYAMA, Yuki, TOGAMI, Katsuhiro, KAWABATA, Kimihito C., NAGASE, Reina, HORIKAWA, Sayuri, HAYASHI, Yasutaka, SAIKA, Makoto, FUKUYAMA, Tomofusa, IZAWA, Kumi, OKI, Toshihiko, NAKAHARA, Fumio, KITAURA, Jiro
Published in Proceedings of the Japan Academy, Series B (2014)
Published in Proceedings of the Japan Academy, Series B (2014)
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Journal Article
A novel ASXL1–OGT axis plays roles in H3K4 methylation and tumor suppression in myeloid malignancies
Inoue, Daichi, Fujino, Takeshi, Sheridan, Paul, Zhang, Yao-zhong, Nagase, Reina, Horikawa, Sayuri, Li, Zaomin, Matsui, Hirotaka, Kanai, Akinori, Saika, Makoto, Yamaguchi, Rui, Kozuka-Hata, Hiroko, Kawabata, Kimihito Cojin, Yokoyama, Akihiko, Goyama, Susumu, Inaba, Toshiya, Imoto, Seiya, Miyano, Satoru, Xu, Mingjiang, Yang, Feng-Chun, Oyama, Masaaki, Kitamura, Toshio
Published in Leukemia (01.06.2018)
Published in Leukemia (01.06.2018)
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Journal Article
Abstract 1851: Responses of a novel tumor selective anti-CD137 agonist antibody activated by elevated extracellular ATP in tumor microenvironment
Kamata-Sakurai, Mika, Narita, Yoshinori, Uchikawa, Ryo, Taniguchi, Kenji, Horikawa, Sayuri, Hamada, Koki, Hori, Yuji, Nemoto, Takayuki, Metsugi, Shoichi, Inatani, Michiyasu, Igawa, Tomoyuki
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Antibody to CD137 Activated by Extracellular Adenosine Triphosphate Is Tumor Selective and Broadly Effective In Vivo without Systemic Immune Activation
Kamata-Sakurai, Mika, Narita, Yoshinori, Hori, Yuji, Nemoto, Takayuki, Uchikawa, Ryo, Honda, Masaki, Hironiwa, Naoka, Taniguchi, Kenji, Shida-Kawazoe, Meiri, Metsugi, Shoichi, Miyazaki, Taro, Wada, Naoko A, Ohte, Yuki, Shimizu, Shun, Mikami, Hirofumi, Tachibana, Tatsuhiko, Ono, Natsuki, Adachi, Kenji, Sakiyama, Tetsushi, Matsushita, Tomochika, Kadono, Shojiro, Komatsu, Shun-Ichiro, Sakamoto, Akihisa, Horikawa, Sayuri, Hirako, Ayano, Hamada, Koki, Naoi, Sotaro, Savory, Nasa, Satoh, Yasuko, Sato, Motohiko, Noguchi, Yuki, Shinozuka, Junko, Kuroi, Haruka, Ito, Ami, Wakabayashi, Tetsuya, Kamimura, Masaki, Isomura, Fumihisa, Tomii, Yasushi, Sawada, Noriaki, Kato, Atsuhiko, Ueda, Otoya, Nakanishi, Yoshito, Endo, Mika, Jishage, Kou-Ichi, Kawabe, Yoshiki, Kitazawa, Takehisa, Igawa, Tomoyuki
Published in Cancer discovery (01.01.2021)
Published in Cancer discovery (01.01.2021)
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Journal Article
SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS
Inoue, D, Kitaura, J, Matsui, H, Hou, H-A, Chou, W-C, Nagamachi, A, Kawabata, K C, Togami, K, Nagase, R, Horikawa, S, Saika, M, Micol, J-B, Hayashi, Y, Harada, Y, Harada, H, Inaba, T, Tien, H-F, Abdel-Wahab, O, Kitamura, T
Published in Leukemia (01.04.2015)
Published in Leukemia (01.04.2015)
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Journal Article
Human NAT10 Is an ATP-dependent RNA Acetyltransferase Responsible for N4-Acetylcytidine Formation in 18 S Ribosomal RNA (rRNA)
Ito, Satoshi, Horikawa, Sayuri, Suzuki, Tateki, Kawauchi, Hiroki, Tanaka, Yoshikazu, Suzuki, Takeo, Suzuki, Tsutomu
Published in The Journal of biological chemistry (26.12.2014)
Published in The Journal of biological chemistry (26.12.2014)
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Journal Article
Novel roles of ASXL1 in epigenetic regulation
Inoue, Daichi, Horikawa, Sayuri, Matsui, Hirotaka, Nagase, Reina, Saika, Makoto, Kawabata, Kimihito C, Goyama, Susumu, Kitamura, Toshio
Published in Experimental hematology (01.09.2015)
Published in Experimental hematology (01.09.2015)
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Journal Article
A C-terminal mutant of CCAAT-enhancer-binding protein α (C/EBPα-Cm ) downregulates Csf1r , a potent accelerator in the progression of acute myeloid leukemia with C/EBPα-Cm
Togami, Katsuhiro, Kitaura, Jiro, Uchida, Tomoyuki, Inoue, Daichi, Nishimura, Koutarou, Kawabata, Kimihito C, Nagase, Reina, Horikawa, Sayuri, Izawa, Kumi, Fukuyama, Tomofusa, Nakahara, Fumio, Oki, Toshihiko, Harada, Yuka, Harada, Hironori, Aburatani, Hiroyuki, Kitamura, Toshio
Published in Experimental hematology (01.04.2015)
Published in Experimental hematology (01.04.2015)
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Journal Article
SETBP1 Mutations Drive Leukemic Transformation in ASXL1-Mutated MDS
Inoue, Daichi, Matsui, Hirotaka, Hou, Hsin-An, Chou, Wen-Chien, Nagamachi, Akiko, Kitaura, Jiro, Kawabata, Kimihito Cojin, Togami, Katsuhiro, Nagase, Reina, Horikawa, Sayuri, Saika, Makoto, Micol, Jean-Baptiste, Hayashi, Yasutaka, Harada, Yuka, Harada, Hironori, Tien, Hwei-Fang, Abdel-Wahab, Omar, Kitamura, Toshio
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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ANTI-CD137 ANTIGEN-BINDING MOLECULE FOR USE IN CANCER TREATMENT
TANIGUCHI, Kenji, HAMADA, Koki, ONO, Natsuki, UCHIKAWA, Ryo, SAKURAI, Mika, HORIKAWA, Sayuri, NARITA, Yoshinori, MIKAMI, Hirofumi
Year of Publication 17.04.2024
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Year of Publication 17.04.2024
Patent
ANTI-CD137 ANTIGEN-BINDING MOLECULE FOR USE IN CANCER TREATMENT
TANIGUCHI, Kenji, HAMADA, Koki, ONO, Natsuki, UCHIKAWA, Ryo, SAKURAI, Mika, HORIKAWA, Sayuri, NARITA, Yoshinori, MIKAMI, Hirofumi
Year of Publication 31.08.2023
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Year of Publication 31.08.2023
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ANTI-CD137 ANTIGEN-BINDING MOLECULE FOR USE IN CANCER TREATMENT
TANIGUCHI, Kenji, HAMADA, Koki, ONO, Natsuki, UCHIKAWA, Ryo, SAKURAI, Mika, HORIKAWA, Sayuri, NARITA, Yoshinori, MIKAMI, Hirofumi
Year of Publication 21.12.2022
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Year of Publication 21.12.2022
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Anti-CD137 antigen-binding molecule for use in cancer treatment
TANIGUCHI, Kenji, HAMADA, Koki, ONO, Natsuki, UCHIKAWA, Ryo, SAKURAI, Mika, HORIKAWA, Sayuri, NARITA, Yoshinori, MIKAMI, Hirofumi
Year of Publication 25.08.2022
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Year of Publication 25.08.2022
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ANTI-CD137 ANTIGEN-BINDING MOLECULE FOR USE IN CANCER TREATMENT
TANIGUCHI, KENJI, HORIKAWA, SAYURI, MIKAMI, HIROFUMI, NARITA, YOSHINORI, UCHIKAWA, RYO, HAMADA, KOKI, SAKURAI, MIKA, ONO, NATSUKI
Year of Publication 19.08.2021
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Year of Publication 19.08.2021
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Anti-CD137 antigen binding molecules for cancer treatment
NARITA YOSHINORI, TANIGUCHI KENJI, HORIKAWA SAYURI, HAMADA KOKI, ONO NATSUO, MIKAMI HIROSHI, UCHIKAWA RYO, SAKURAI MIKA
Year of Publication 06.12.2022
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Year of Publication 06.12.2022
Patent
ANTI-CD137 ANTIGEN-BINDING MOLECULE FOR USE IN CANCER TREATMENT
TANIGUCHI, Kenji, HAMADA, Koki, ONO, Natsuki, UCHIKAWA, Ryo, HORIKAWA, Sayuri, SAKURAI, Mika, NARITA, Yoshinori, MIKAMI, Hirofumi
Year of Publication 31.10.2022
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Year of Publication 31.10.2022
Patent