Carnosine scavenging of glucolipotoxic free radicals enhances insulin secretion and glucose uptake
Cripps, Michael J, Hanna, Katie, Lavilla, Jr, Charlie, Sayers, Sophie R, Caton, Paul W, Sims, Craig, De Girolamo, Luigi, Sale, Craig, Turner, Mark D
Published in Scientific reports (17.10.2017)
Published in Scientific reports (17.10.2017)
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Journal Article
Psoriatic skin inflammation induces a pre-diabetic phenotype via the endocrine actions of skin secretome
Evans, Elizabeth A., Sayers, Sophie R., Kodji, Xenia, Xia, Yue, Shaikh, Mahum, Rizvi, Alizah, Frame, James, Brain, Susan D., Philpott, Michael P., Hannen, Rosalind F., Caton, Paul W.
Published in Molecular metabolism (Germany) (01.11.2020)
Published in Molecular metabolism (Germany) (01.11.2020)
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Journal Article
Proglucagon Promoter Cre-Mediated AMPK Deletion in Mice Increases Circulating GLP-1 Levels and Oral Glucose Tolerance
Sayers, Sophie R, Reimann, Frank, Gribble, Fiona M, Parker, Helen, Zac-Varghese, Sagen, Bloom, Stephen R, Foretz, Marc, Viollet, Benoit, Rutter, Guy A
Published in PloS one (24.03.2016)
Published in PloS one (24.03.2016)
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Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes
Sayers, Sophie R., Beavil, Rebecca L., Fine, Nicholas H. F., Huang, Guo C., Choudhary, Pratik, Pacholarz, Kamila J., Barran, Perdita E., Butterworth, Sam, Mills, Charlotte E., Cruickshank, J. Kennedy, Silvestre, Marta P., Poppitt, Sally D., McGill, Anne-Thea, Lavery, Gareth G., Hodson, David J., Caton, Paul W.
Published in Diabetologia (01.02.2020)
Published in Diabetologia (01.02.2020)
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Carnosine protects stimulus-secretion coupling through prevention of protein carbonyl adduction events in cells under metabolic stress
Lavilla, Charlie Jr, Billacura, Merell P., Hanna, Katie, Boocock, David J., Coveney, Clare, Miles, Amanda K., Foulds, Gemma A., Murphy, Alice, Tan, Arnold, Jackisch, Laura, Sayers, Sophie R., Caton, Paul W., Doig, Craig L., McTernan, Philip G., Colombo, Sergio L., Sale, Craig, Turner, Mark D.
Published in Free radical biology & medicine (01.11.2021)
Published in Free radical biology & medicine (01.11.2021)
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Journal Article
Monomeric eNAMPT in the development of experimental diabetes in mice: a potential target for type 2 diabetes treatment
Kieswich, Julius, Sayers, Sophie R., Silvestre, Marta F., Harwood, Steven M., Yaqoob, Muhammad M., Caton, Paul W.
Published in Diabetologia (01.11.2016)
Published in Diabetologia (01.11.2016)
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Journal Article
Identification of a subset of trace amine-associated receptors and ligands as potential modulators of insulin secretion
Cripps, Michael J., Bagnati, Marta, Jones, Tania A., Ogunkolade, Babatunji W., Sayers, Sophie R., Caton, Paul W., Hanna, Katie, Billacura, Merell P., Fair, Kathryn, Nelson, Carl, Lowe, Robert, Hitman, Graham A., Berry, Mark D., Turner, Mark D.
Published in Biochemical pharmacology (01.01.2020)
Published in Biochemical pharmacology (01.01.2020)
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Disallowance of Acot7 in [Beta]-Cells Is Required for Normal Glucose Tolerance and Insulin Secretion
Martinez-Sanchez, Aida, Pullen, Timothy J, Chabosseau, Pauline, Zhang, Qifeng, Haythorne, Elizabeth, Cane, Matthew C, Nguyen-Tu, Marie-Sophie, Sayers, Sophie R, Rutter, Guy A
Published in Diabetes (New York, N.Y.) (01.05.2016)
Published in Diabetes (New York, N.Y.) (01.05.2016)
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Journal Article
Disallowance of Acot7 in β-Cells Is Required for Normal Glucose Tolerance and Insulin Secretion
Martinez-Sanchez, Aida, Pullen, Timothy J, Chabosseau, Pauline, Zhang, Qifeng, Haythorne, Elizabeth, Cane, Matthew C, Nguyen-Tu, Marie-Sophie, Sayers, Sophie R, Rutter, Guy A
Published in Diabetes (New York, N.Y.) (01.05.2016)
Published in Diabetes (New York, N.Y.) (01.05.2016)
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Journal Article