Oral uridine pro-drug PN401 is neuroprotective in the R6/2 and N171-82Q mouse models of Huntington's disease
Saydoff, Joel A., Garcia, Rolando A.G., Browne, Susan E., Liu, Liansheng, Sheng, Jin, Brenneman, Denise, Hu, Zhongyi, Cardin, Sylvain, Gonzalez, Alexis, von Borstel, Reid W., Gregorio, Jason, Burr, Holly, Beal, M. Flint
Published in Neurobiology of disease (01.12.2006)
Published in Neurobiology of disease (01.12.2006)
Get full text
Journal Article
Prompt treatment with uridine triacetate improves survival and reduces toxicity due to fluorouracil and capecitabine overdose or dihydropyrimidine dehydrogenase deficiency
Garcia, Rolando A.G., Saydoff, Joel A., Bamat, Michael K., von Borstel, Reid W.
Published in Toxicology and applied pharmacology (15.08.2018)
Published in Toxicology and applied pharmacology (15.08.2018)
Get full text
Journal Article
Uridine prodrug improves memory in Tg2576 and TAPP mice and reduces pathological factors associated with Alzheimer's disease in related models
Saydoff, Joel A, Olariu, Ana, Sheng, Jin, Hu, Zhongyi, Li, Qin, Garcia, Rolando, Pei, Jiong, Sun, Grace Y, von Borstel, Reid
Published in Journal of Alzheimer's disease (01.01.2013)
Published in Journal of Alzheimer's disease (01.01.2013)
Get more information
Journal Article
5'-O-페닐아세틸우리딘 및 치료 용도
SAYDOFF JOEL A, SIMPSON DAVID MICHAEL, VON BORSTEL REID WARREN, GARCIA GARCIA ROLANDO ALEJANDRO
Year of Publication 26.07.2023
Get full text
Year of Publication 26.07.2023
Patent
Oral uridine pro-drug PN401 decreases neurodegeneration, behavioral impairment, weight loss and mortality in the 3-nitropropionic acid mitochondrial toxin model of Huntington's disease
Saydoff, Joel A., Liu, Lian Sheng, Garcia, Rolando A.G., Hu, Zhongyi, Li, Donna, von Borstel, Reid W.
Published in Brain research (19.12.2003)
Published in Brain research (19.12.2003)
Get full text
Journal Article
Severe cytochrome c oxidase inhibition in vivo does not induce a pyrimidine deficiency; neuroprotective action of oral uridine prodrug PN401 requires supraphysiological levels of uridine
Garcia, Rolando A.G., Liu, Liansheng, Hu, Zhongyi, Gonzalez, Alexis, von Borstel, Reid W., Saydoff, Joel A.
Published in Brain research (20.12.2005)
Published in Brain research (20.12.2005)
Get full text
Journal Article
P4-307: PN401 treatment improves memory in Tg2576 and TAPP models of Alzheimer's disease
Saydoff, Joel A, Olariu, Ana, Hu, Zhongyi, Sheng, Jin, Pei, Jiong, Li, Qin, Garcia, Rolando, Brenneman, Denise, von Borstel, Reid W
Published in Alzheimer's & dementia (01.07.2008)
Published in Alzheimer's & dementia (01.07.2008)
Get full text
Journal Article
Numerous adrenal chromaffin cell preparations fail to produce analgesic effects in the formalin test or in tests of acute pain even with nicotine stimulation
Lindner, Mark D, Francis, Jonathan M, McDermott, Patricia E, Bell, William J, Blaney, Thomas J, Sherman, Sandy S, Saydoff, Joel A
Published in Pain (Amsterdam) (01.11.2000)
Published in Pain (Amsterdam) (01.11.2000)
Get full text
Journal Article
The analgesic potential of intraventricular polymer-encapsulated adrenal chromaffin cells in a rodent model of chronic neuropathic pain
Lindner, M D, Francis, J M, Plone, M A, McDermott, P E, Frydel, B R, Emerich, D F, Saydoff, J A
Published in Experimental and clinical psychopharmacology (01.11.2000)
Published in Experimental and clinical psychopharmacology (01.11.2000)
Get more information
Journal Article
5'-O-PHENYLACETYLURIDINE AND THERAPEUTIC USE
GARCIA GARCIA, Rolando Alejandro, SIMPSON, David Michael, SAYDOFF, Joel A, VON BORSTEL, Reid Warren
Year of Publication 11.09.2024
Get full text
Year of Publication 11.09.2024
Patent
5'-O-PHENYLACETYLURIDINE AND THERAPEUTIC USE
GARCIA GARCIA, Rolando Alejandro, SIMPSON, David Michael, SAYDOFF, Joel A, VON BORSTEL, Reid Warren
Year of Publication 18.07.2024
Get full text
Year of Publication 18.07.2024
Patent
5'-O-Phenylacetyluridine and therapeutic use
GARCIA GARCIA, ROLANDO ALEJANDRO, SIMPSON, David Michael, SAYDOFF, Joel A, VON BORSTEL, Reid Warren
Year of Publication 28.12.2023
Get full text
Year of Publication 28.12.2023
Patent
5'-O-PHENYLACETYLURIDINE AND THERAPEUTIC USE
GARCIA GARCIA, Rolando Alejandro, SIMPSON, David Michael, SAYDOFF, Joel A, VON BORSTEL, Reid Warren
Year of Publication 11.10.2023
Get full text
Year of Publication 11.10.2023
Patent
5'-O-PHENYLACETYLURIDINE AND THERAPEUTIC USE
GARCIA GARCIA, Rolando Alejandro, SIMPSON, David Michael, SAYDOFF, Joel A, VON BORSTEL, Reid Warren
Year of Publication 20.07.2023
Get full text
Year of Publication 20.07.2023
Patent