The SH2 tyrosine phosphatase Shp2 is required for mammalian limb development
Saxton, Tracy M, Pawson, Tony, Ciruna, Brian G, Holmyard, Doug, Kulkarni, Sarang, Harpal, Ken, Rossant, Janet
Published in Nature genetics (01.04.2000)
Published in Nature genetics (01.04.2000)
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Journal Article
Morphogenetic Movements at Gastrulation Require the SH2 Tyrosine Phosphatase Shp2
Saxton, Tracy M., Pawson, Tony
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.1999)
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Journal Article
Evidence for a functional subclass of the RTVL-H family of human endogenous retrovirus-like sequences
WILKINSON, D. A, GOODCHILD, N. L, SAXTON, T. M, WOOD, S, MAGER, D. L
Published in Journal of Virology (01.06.1993)
Published in Journal of Virology (01.06.1993)
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Journal Article
Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2
Saxton, Tracy M., Henkemeyer, Mark, Gasca, Stephan, Shen, Randy, Rossi, Derrick J., Shalaby, Fouad, Feng, Gen-Sheng, Pawson, Tony
Published in The EMBO journal (01.05.1997)
Published in The EMBO journal (01.05.1997)
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Journal Article
Nuk Controls Pathfinding of Commissural Axons in the Mammalian Central Nervous System
Henkemeyer, Mark, Orioli, Donata, Henderson, Jeffrey T, Saxton, Tracy M, Roder, John, Pawson, Tony, Klein, Rüdiger
Published in Cell (12.07.1996)
Published in Cell (12.07.1996)
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Journal Article
Mammalian Grb2 Regulates Multiple Steps in Embryonic Development and Malignant Transformation
Cheng, Alec M, Saxton, Tracy M, Sakai, Ryuichi, Kulkarni, Sarang, Mbamalu, Geraldine, Vogel, Wolfgang, Tortorice, Christopher G, Cardiff, Robert D, Cross, James C, Muller, William J, Pawson, Tony
Published in Cell (11.12.1998)
Published in Cell (11.12.1998)
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Journal Article
Regulation of Early Events in Integrin Signaling by Protein Tyrosine Phosphatase SHP-2
Oh, Eok-Soo, Gu, Haihua, Saxton, Tracy M., Timms, John F., Hausdorff, Sharon, Frevert, Ernst U., Kahn, Barbara B., Pawson, Tony, Neel, Benjamin G., Thomas, Sheila M.
Published in Molecular and Cellular Biology (01.04.1999)
Published in Molecular and Cellular Biology (01.04.1999)
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Journal Article
The Mammalian ShcB and ShcC Phosphotyrosine Docking Proteins Function in the Maturation of Sensory and Sympathetic Neurons
Sakai, Ryuichi, Henderson, Jeffrey T., O'Bryan, John P., Elia, Andrew J., Saxton, Tracy M., Pawson, Tony
Published in Neuron (Cambridge, Mass.) (01.12.2000)
Published in Neuron (Cambridge, Mass.) (01.12.2000)
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Journal Article
Gene dosage-dependent functions for phosphotyrosine-Grb2 signaling during mammalian tissue morphogenesis
Saxton, Tracy M, Cheng, Alec M, Ong, Siew Hwa, Lu, Yong, Sakai, Ryuichi, Cross, James C, Pawson, Tony
Published in Current biology (01.05.2001)
Published in Current biology (01.05.2001)
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Journal Article
B cell antigen receptor cross-linking induces phosphorylation of the p21ras oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kDa tyrosine- phosphorylated protein
Saxton, TM, van Oostveen, I, Bowtell, D, Aebersold, R, Gold, MR
Published in The Journal of immunology (1950) (15.07.1994)
Published in The Journal of immunology (1950) (15.07.1994)
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Journal Article
Activation and serine phosphorylation of the p56lck protein tyrosine kinase in response to antigen receptor cross-linking in B lymphocytes
Gold, MR, Chiu, R, Ingham, RJ, Saxton, TM, van Oostveen, I, Watts, JD, Affolter, M, Aebersold, R
Published in The Journal of immunology (1950) (15.09.1994)
Published in The Journal of immunology (1950) (15.09.1994)
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Journal Article
Physiological and perceptual responses to upper- and lower-limb aerobic exercise in patients with peripheral arterial disease
Zwierska, I, Male, J S, Choksy, SA, Pockley, A G, Saxton, T M
Published in Journal of Sports Sciences (01.02.2005)
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Published in Journal of Sports Sciences (01.02.2005)
Conference Proceeding
B cell antigen receptor cross-linking induces phosphorylation of the p21 super(ras) oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kDa tyrosine-phosphorylated protein
Saxton, T M, Van Oostveen, I, Bowtell, D, Aebersold, R, Gold, M R
Published in The Journal of immunology (1950) (01.01.1994)
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Published in The Journal of immunology (1950) (01.01.1994)
Journal Article
Activation and serine phosphorylation of the p56 super(lck) protein tyrosine kinase in response to antigen receptor cross-linking in B lymphocytes
Gold, M R, Chiu, R, Ingham, R J, Saxton, T M, Van Oostveen, I, Watts, J D, Affolter, M, Aebersold, R
Published in The Journal of immunology (1950) (01.01.1994)
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Published in The Journal of immunology (1950) (01.01.1994)
Journal Article