Metabolism, Excretion, and Mass Balance of the HIV-1 Integrase Inhibitor Dolutegravir in Humans
CASTELLINO, Stephen, MOSS, Lee, PISCITELLI, Stephen C, SAVINA, Paul M, WAGNER, David, BORLAND, Julie, SONG, Ivy, SHUGUANG CHEN, YU LOU, MIN, Sherene S, GOLJER, Igor, CULP, Amanda
Published in Antimicrobial Agents and Chemotherapy (01.08.2013)
Published in Antimicrobial Agents and Chemotherapy (01.08.2013)
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In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor
Reese, Melinda J, Savina, Paul M, Generaux, Grant T, Tracey, Helen, Humphreys, Joan E, Kanaoka, Eri, Webster, Lindsey O, Harmon, Kelly A, Clarke, James D, Polli, Joseph W
Published in Drug metabolism and disposition (01.02.2013)
Published in Drug metabolism and disposition (01.02.2013)
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Pharmacokinetics of Single‐Dose Dolutegravir in HIV‐Seronegative Subjects With Moderate Hepatic Impairment Compared to Healthy Matched Controls
Song, Ivy H., Borland, Julie, Savina, Paul M., Chen, Shuguang, Patel, Parul, Wajima, Toshihiro, Peppercorn, Amanda F., Piscitelli, Stephen C.
Published in Clinical pharmacology in drug development (01.10.2013)
Published in Clinical pharmacology in drug development (01.10.2013)
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Evaluation of the Carcinogenic Potential of Clofibrate in FVB/Tg.AC Mouse After Oral Administration—Part I
Torrey, Carla E., Wall, Henry G., Campbell, James A., Kwanyuen, Puntipa, Hoivik, Debie J., Miller, Richard T., Allen, Jane S., Jayo, Manuel J., Selinger, Krzysztof, Savina, Paul M., Santostefano, Michael J.
Published in International journal of toxicology (01.09.2005)
Published in International journal of toxicology (01.09.2005)
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Evaluation of the Carcinogenic Potential of Clofibrate in the p53+ / − Mouse
Torrey, Carla E., Campbell, James A., Hoivik, Debie J., Miller, Richard T., Allen, Jane S., Mann, Peter C., Selinger, Krzysztof, Rickert, Douglas, Savina, Paul M., Santostefano, Michael J.
Published in International journal of toxicology (01.09.2005)
Published in International journal of toxicology (01.09.2005)
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Melphalan transport, glutathione levels, and glutathione-S-transferase activity in human medulloblastoma
FRIEDMAN, H. S, SKAPEK, S. X, COLVIN, O. M, ELION, G. B, BLUM, M. R, SAVINA, P. M, HILTON, J, CLIFFORD SCHOLD, S. JR, KURTZBERG, J, BIGNER, D. D
Published in Cancer research (Chicago, Ill.) (01.10.1988)
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Published in Cancer research (Chicago, Ill.) (01.10.1988)
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Therapeutic analysis of melphalan-resistant human rhabdomyosarcoma xenograft TE-671 MR
LILLEY, E. R, ELION, G. B, DEWHIRST, M. W, SCHOLD, S. C, BLUM, M. R, SAVINA, P. M, LAMSKOWITZ, D. T, BIGNER, D. D, FRIEDMAN, H. S
Published in Cancer research (Chicago, Ill.) (01.08.1991)
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Published in Cancer research (Chicago, Ill.) (01.08.1991)
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Validation of a high-performance liquid chromatographic-mass spectrometric method for the measurement of 5-chloro-2′,3′-dideoxy-3′-fluorouridine (935U83) in human plasma
Dunn, John A., Savina, Paul M.
Published in Journal of chromatography. B, Biomedical applications (15.11.1996)
Published in Journal of chromatography. B, Biomedical applications (15.11.1996)
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Safety and pharmacokinetics of 5-chloro-2',3'-dideoxy-3'-fluorouridine (935U83) following oral administration of escalating single doses in human immunodeficiency virus-infected adults
RIDDLER, S. A, WANG, L. H, BARTLETT, J. A, SAVINA, P. M, PACKARD, M. V, MCMAHON, D. K, BLUM, M. R, DUNN, J. A, ELKINS, M. M, MELLORS, J. W
Published in Antimicrobial Agents and Chemotherapy (01.12.1996)
Published in Antimicrobial Agents and Chemotherapy (01.12.1996)
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Hyperthermia-induced enhancement of melphalan activity against a melphalan-resistant human rhabdomyosarcoma xenograft
Laskowitz, D T, Elion, G B, Dewhirst, M W, Griffith, O W, Savina, P M, Blum, M R, Prescott, D M, Bigner, D D, Friedman, H S
Published in Radiation research (01.02.1992)
Published in Radiation research (01.02.1992)
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Optimal perfusion rate determined for in situ intestinal absorption studies in rats
Savina, P M, Staubus, A E, Gaginella, T S, Smith, D F
Published in Journal of pharmaceutical sciences (01.03.1981)
Published in Journal of pharmaceutical sciences (01.03.1981)
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