Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis
Koczor, Christopher A., Saville, Kate M., Andrews, Joel F., Clark, Jennifer, Fang, Qingming, Li, Jianfeng, Al-Rahahleh, Rasha Q., Ibrahim, Md, McClellan, Steven, Makarov, Mikhail V., Migaud, Marie E., Sobol, Robert W.
Published in Cell reports (Cambridge) (02.11.2021)
Published in Cell reports (Cambridge) (02.11.2021)
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NAD + bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells
Li, Jianfeng, M Saville, Kate, Ibrahim, Md, Zeng, Xuemei, McClellan, Steve, Angajala, Anusha, Beiser, Alison, Andrews, Joel F, Sun, Mai, Koczor, Christopher A, Clark, Jennifer, Hayat, Faisal, Makarov, Mikhail V, Wilk, Anna, Yates, Nathan A, Migaud, Marie E, Sobol, Robert W
Published in NAR cancer (01.12.2021)
Published in NAR cancer (01.12.2021)
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NAD+-mediated regulation of mammalian base excision repair
Saville, Kate M., Clark, Jennifer, Wilk, Anna, Rogers, Gresyn D., Andrews, Joel F., Koczor, Christopher A., Sobol, Robert W.
Published in DNA repair (01.09.2020)
Published in DNA repair (01.09.2020)
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Quantitative Analysis of Nuclear Poly(ADP-Ribose) Dynamics in Response to Laser-Induced DNA Damage
Koczor, Christopher A, Saville, Kate M, Al-Rahahleh, Rasha Q, Andrews, Joel F, Li, Jianfeng, Sobol, Robert W
Published in Methods in molecular biology (Clifton, N.J.) (2023)
Published in Methods in molecular biology (Clifton, N.J.) (2023)
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Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity
Saville, Kate M., Al-Rahahleh, Rasha Q., Siddiqui, Aisha H., Andrews, Morgan E., Roos, Wynand P., Koczor, Christopher A., Andrews, Joel F., Hayat, Faisal, Migaud, Marie E., Sobol, Robert W.
Published in DNA repair (01.08.2024)
Published in DNA repair (01.08.2024)
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Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD + Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase
Li, Jianfeng, Koczor, Christopher A, Saville, Kate M, Hayat, Faisal, Beiser, Alison, McClellan, Steven, Migaud, Marie E, Sobol, Robert W
Published in Cancers (22.07.2022)
Published in Cancers (22.07.2022)
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Journal Article
Live Cell Detection of Poly(ADP-Ribose) for Use in Genetic and Genotoxic Compound Screens
Koczor, Christopher A, Haider, Aaron J, Saville, Kate M, Li, Jianfeng, Andrews, Joel F, Beiser, Alison V, Sobol, Robert W
Published in Cancers (28.07.2022)
Published in Cancers (28.07.2022)
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Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage
Al-Rahahleh, Rasha Q, Saville, Kate M, Andrews, Joel F, Wu, Zhijin, Koczor, Christopher A, Sobol, Robert W
Published in bioRxiv (29.12.2023)
Published in bioRxiv (29.12.2023)
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Abstract 5166: Sensitivity of melanoma cells to a novel class of Ras inhibitors
Saville, Kate M., Lee, Kevin, Mattox, Tyler E., Chen, Xi, Valiyaveettil, Jacob, Berry, Kristy, Ramírez-Alcántara, Veronica, Zhu, Bing, Keeton, Adam, Boyd, Michael, Piazza, Gary, Lindsey, Ashley S.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Temporal dynamics of base excision / single-strand break repair protein complex assembly and disassembly are modulated by the PARP1/NAD+/SIRT6 axis
Koczor, Christopher A, Saville, Kate M, Andrews, Joel F, Clark, Jennifer, Fang, Qingming, Li, Jianfeng, Makarov, Mikhail V, Migaud, Marie E, Sobol, Robert W
Published in bioRxiv (04.04.2021)
Published in bioRxiv (04.04.2021)
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