Staphylococcus aureus Biofilms Promote Horizontal Transfer of Antibiotic Resistance
Savage, Victoria J, Chopra, Ian, O'Neill, Alex J
Published in Antimicrobial Agents and Chemotherapy (01.04.2013)
Published in Antimicrobial Agents and Chemotherapy (01.04.2013)
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Journal Article
Evaluation of Homogentisic Acid, a Prospective Antibacterial Agent Highlighted by the Suitability of Nitisinone in Alkaptonuria 2 (SONIA 2) Clinical Trial
Ooi, Nicola, Cooper, Ian R, Norman, Brendan, Gallagher, James A, Sireau, Nick, Bou-Gharios, George, Ranganath, Lakshminarayan R, Savage, Victoria J
Published in Cells (Basel, Switzerland) (21.06.2023)
Published in Cells (Basel, Switzerland) (21.06.2023)
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Journal Article
Restoring carbapenem efficacy: a novel carbapenem companion targeting metallo-β-lactamases in carbapenem-resistant Enterobacterales
Ooi, Nicola, Lee, Victoria E, Chalam-Judge, Nathan, Newman, Rebecca, Wilkinson, Andrew J, Cooper, Ian R, Orr, David, Lee, Sally, Savage, Victoria J
Published in Journal of antimicrobial chemotherapy (19.01.2021)
Published in Journal of antimicrobial chemotherapy (19.01.2021)
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Journal Article
Discovery and structure–activity relationships of a novel oxazolidinone class of bacterial type II topoisomerase inhibitors
Lyons, Amanda, Kirkham, James, Blades, Kevin, Orr, David, Dauncey, Elizabeth, Smith, Oliver, Dick, Emma, Walker, Rolf, Matthews, Teresa, Bunt, Adam, Finlayson, Jonathan, Morrison, Ian, Savage, Victoria J., Moyo, Emmanuel, Butler, Hayley S., Newman, Rebecca, Ooi, Nicola, Smith, Andrew, Charrier, Cédric, Ratcliffe, Andrew J., Stokes, Neil R., Best, Stuart, Salisbury, Anne-Marie, Craighead, Mark, Cooper, Ian R.
Published in Bioorganic & medicinal chemistry letters (01.06.2022)
Published in Bioorganic & medicinal chemistry letters (01.06.2022)
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Journal Article
Novel Bacterial Topoisomerase Inhibitors with Potent Broad-Spectrum Activity against Drug-Resistant Bacteria
Charrier, Cédric, Salisbury, Anne-Marie, Savage, Victoria J, Duffy, Thomas, Moyo, Emmanuel, Chaffer-Malam, Nathan, Ooi, Nicola, Newman, Rebecca, Cheung, Jonathan, Metzger, Richard, McGarry, David, Pichowicz, Mark, Sigerson, Ralph, Cooper, Ian R, Nelson, Gary, Butler, Hayley S, Craighead, Mark, Ratcliffe, Andrew J, Best, Stuart A, Stokes, Neil R
Published in Antimicrobial agents and chemotherapy (01.05.2017)
Published in Antimicrobial agents and chemotherapy (01.05.2017)
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Journal Article
Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors
Wilkinson, Andrew J., Ooi, Nicola, Finlayson, Jonathan, Lee, Victoria E., Lyth, David, Maskew, Kathryn S., Newman, Rebecca, Orr, David, Ansell, Keith, Birchall, Kristian, Canning, Peter, Coombs, Peter, Fusani, Lucia, McIver, Ed, Pisco, João, Ireland, Philip M., Jenkins, Christopher, Norville, Isobel H., Southern, Stephanie J., Cowan, Richard, Hall, Gareth, Kettleborough, Catherine, Savage, Victoria J., Cooper, Ian R.
Published in Bioorganic & medicinal chemistry letters (15.06.2023)
Published in Bioorganic & medicinal chemistry letters (15.06.2023)
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Journal Article
Biological profiling of novel tricyclic inhibitors of bacterial DNA gyrase and topoisomerase IV
Savage, Victoria J, Charrier, Cédric, Salisbury, Anne-Marie, Moyo, Emmanuel, Forward, Henry, Chaffer-Malam, Nathan, Metzger, Richard, Huxley, Anthony, Kirk, Ralph, Uosis-Martin, Mario, Noonan, Gary, Mohmed, Sarfraz, Best, Stuart A, Ratcliffe, Andrew J, Stokes, Neil R
Published in Journal of antimicrobial chemotherapy (01.07.2016)
Published in Journal of antimicrobial chemotherapy (01.07.2016)
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Journal Article
Design, synthesis and antibacterial properties of pyrimido[4,5-b]indol-8-amine inhibitors of DNA gyrase
McGarry, David H., Cooper, Ian R., Walker, Rolf, Warrilow, Catherine E., Pichowicz, Mark, Ratcliffe, Andrew J., Salisbury, Anne-Marie, Savage, Victoria J., Moyo, Emmanuel, Maclean, John, Smith, Andrew, Charrier, Cédric, Stokes, Neil R., Lindsay, David M., Kerr, William J.
Published in Bioorganic & medicinal chemistry letters (15.09.2018)
Published in Bioorganic & medicinal chemistry letters (15.09.2018)
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Journal Article
Efficacy of a Novel Tricyclic Topoisomerase Inhibitor in a Murine Model of Neisseria gonorrhoeae Infection
Savage, Victoria J, Charrier, Cédric, Salisbury, Anne-Marie, Box, Helen, Chaffer-Malam, Nathan, Huxley, Anthony, Kirk, Ralph, Noonan, Gary M, Mohmed, Sarfraz, Craighead, Mark W, Ratcliffe, Andrew J, Best, Stuart A, Stokes, Neil R
Published in Antimicrobial agents and chemotherapy (01.09.2016)
Published in Antimicrobial agents and chemotherapy (01.09.2016)
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Journal Article
In vitro biological evaluation of novel broad-spectrum isothiazolone inhibitors of bacterial type II topoisomerases
Charrier, Cédric, Salisbury, Anne-Marie, Savage, Victoria J, Moyo, Emmanuel, Forward, Henry, Ooi, Nicola, Cheung, Jonathan, Metzger, Richard, McGarry, David, Walker, Rolf, Cooper, Ian R, Ratcliffe, Andrew J, Stokes, Neil R
Published in Journal of antimicrobial chemotherapy (01.10.2016)
Published in Journal of antimicrobial chemotherapy (01.10.2016)
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Journal Article
Discovery and structure–activity relationships of a novel isothiazolone class of bacterial type II topoisomerase inhibitors
Cooper, Ian R., McCarroll, Andrew J., McGarry, David, Kirkham, James, Pichowicz, Mark, Walker, Rolf, Warrilow, Catherine, Salisbury, Anne-Marie, Savage, Victoria J., Moyo, Emmanuel, Forward, Henry, Cheung, Jonathan, Metzger, Richard, Gault, Zoe, Nelson, Gary, Hughes, Diarmaid, Cao, Sha, Maclean, John, Charrier, Cédric, Craighead, Mark, Best, Stuart, Stokes, Neil R., Ratcliffe, Andrew J.
Published in Bioorganic & medicinal chemistry letters (01.09.2016)
Published in Bioorganic & medicinal chemistry letters (01.09.2016)
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