Old Drugs for a New Virus: Repurposed Approaches for Combating COVID-19
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Versatile Trans-Replication Systems for Chikungunya Virus Allow Functional Analysis and Tagging of Every Replicase Protein
Utt, Age, Quirin, Tania, Saul, Sirle, Hellström, Kirsi, Ahola, Tero, Merits, Andres
Published in PloS one (10.03.2016)
Published in PloS one (10.03.2016)
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Optimization of 4-Anilinoquinolines as Dengue Virus Inhibitors
Huang, Pei-Tzu, Saul, Sirle, Einav, Shirit, Asquith, Christopher R M
Published in Molecules (Basel, Switzerland) (03.12.2021)
Published in Molecules (Basel, Switzerland) (03.12.2021)
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Safe and Effective Treatment of Experimental Neuroblastoma and Glioblastoma Using Systemically Delivered Triple MicroRNA-Detargeted Oncolytic Semliki Forest Virus
Ramachandran, Mohanraj, Yu, Di, Dyczynski, Matheus, Baskaran, Sathishkumar, Zhang, Lei, Lulla, Aleksei, Lulla, Valeria, Saul, Sirle, Nelander, Sven, Dimberg, Anna, Merits, Andres, Leja-Jarblad, Justyna, Essand, Magnus
Published in Clinical cancer research (15.03.2017)
Published in Clinical cancer research (15.03.2017)
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Magnetic Fractionation and Proteomic Dissection of Cellular Organelles Occupied by the Late Replication Complexes of Semliki Forest Virus
Varjak, Margus, Saul, Sirle, Arike, Liisa, Lulla, Aleksei, Peil, Lauri, Merits, Andres
Published in Journal of Virology (01.09.2013)
Published in Journal of Virology (01.09.2013)
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Viral Polymerase-Helicase Complexes Regulate Replication Fidelity To Overcome Intracellular Nucleotide Depletion
Stapleford, Kenneth A, Rozen-Gagnon, Kathryn, Das, Pratyush Kumar, Saul, Sirle, Poirier, Enzo Z, Blanc, Hervé, Vidalain, Pierre-Olivier, Merits, Andres, Vignuzzi, Marco
Published in Journal of virology (01.11.2015)
Published in Journal of virology (01.11.2015)
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Anticancer pan-ErbB inhibitors reduce inflammation and tissue injury and exert broad-spectrum antiviral effects
Saul, Sirle, Karim, Marwah, Ghita, Luca, Huang, Pei-Tzu, Chiu, Winston, Durán, Verónica, Lo, Chieh-Wen, Kumar, Sathish, Bhalla, Nishank, Leyssen, Pieter, Alem, Farhang, Boghdeh, Niloufar A, Tran, Do Hn, Cohen, Courtney A, Brown, Jacquelyn A, Huie, Kathleen E, Tindle, Courtney, Sibai, Mamdouh, Ye, Chengjin, Khalil, Ahmed Magdy, Chiem, Kevin, Martinez-Sobrido, Luis, Dye, John M, Pinsky, Benjamin A, Ghosh, Pradipta, Das, Soumita, Solow-Cordero, David E, Jin, Jing, Wikswo, John P, Jochmans, Dirk, Neyts, Johan, De Jonghe, Steven, Narayanan, Aarthi, Einav, Shirit
Published in The Journal of clinical investigation (01.10.2023)
Published in The Journal of clinical investigation (01.10.2023)
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Reverse genetic system, genetically stable reporter viruses and packaged subgenomic replicon based on a Brazilian Zika virus isolate
Mutso, Margit, Saul, Sirle, Rausalu, Kai, Susova, Olga, Žusinaite, Eva, Mahalingam, Suresh, Merits, Andres
Published in Journal of general virology (01.11.2017)
Published in Journal of general virology (01.11.2017)
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The transcriptional landscape of Venezuelan equine encephalitis virus (TC-83) infection
Yao, Zhiyuan, Zanini, Fabio, Kumar, Sathish, Karim, Marwah, Saul, Sirle, Bhalla, Nishank, Panpradist, Nuttada, Muniz, Avery, Narayanan, Aarthi, Quake, Stephen R, Einav, Shirit
Published in PLoS neglected tropical diseases (01.03.2021)
Published in PLoS neglected tropical diseases (01.03.2021)
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An 8-gene machine learning model improves clinical prediction of severe dengue progression
Liu, Yiran E, Saul, Sirle, Rao, Aditya Manohar, Robinson, Makeda Lucretia, Agudelo Rojas, Olga Lucia, Sanz, Ana Maria, Verghese, Michelle, Solis, Daniel, Sibai, Mamdouh, Huang, Chun Hong, Sahoo, Malaya Kumar, Gelvez, Rosa Margarita, Bueno, Nathalia, Estupiñan Cardenas, Maria Isabel, Villar Centeno, Luis Angel, Rojas Garrido, Elsa Marina, Rosso, Fernando, Donato, Michele, Pinsky, Benjamin A, Einav, Shirit, Khatri, Purvesh
Published in Genome medicine (29.03.2022)
Published in Genome medicine (29.03.2022)
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Mutation of CD2AP and SH3KBP1 Binding Motif in Alphavirus nsP3 Hypervariable Domain Results in Attenuated Virus
Mutso, Margit, Morro, Ainhoa Moliner, Smedberg, Cecilia, Kasvandik, Sergo, Aquilimeba, Muriel, Teppor, Mona, Tarve, Liisi, Lulla, Aleksei, Lulla, Valeria, Saul, Sirle, Thaa, Bastian, McInerney, Gerald M, Merits, Andres, Varjak, Margus
Published in Viruses (27.04.2018)
Published in Viruses (27.04.2018)
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Synthesis and evaluation of 3-alkynyl-5-aryl-7-aza-indoles as broad-spectrum antiviral agents
Martinez-Gualda, Belén, Graus, Mirthe, Camps, Anita, Vanhulle, Emiel, Saul, Sirle, Azari, Siavash, Nhu Tran, Do Hoang, Vangeel, Laura, Chiu, Winston, Neyts, Johan, Schols, Dominique, Einav, Shirit, Vermeire, Kurt, De Jonghe, Steven
Published in Frontiers in chemistry (26.10.2022)
Published in Frontiers in chemistry (26.10.2022)
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Reverse genetic system, genetically stable reporter viruses and packaged subgenomic replicon based on a Brazilian Zika virus isolate
Mutso, Margit, Saul, Sirle, Rausalu, Kai, Susova, Olga, Žusinaite, Eva, Mahalingam, Suresh, Merits, Andres
Published in Journal of general virology (01.11.2017)
Published in Journal of general virology (01.11.2017)
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Obatoclax Inhibits Alphavirus Membrane Fusion by Neutralizing the Acidic Environment of Endocytic Compartments
Varghese, Finny S, Rausalu, Kai, Hakanen, Marika, Saul, Sirle, Kümmerer, Beate M, Susi, Petri, Merits, Andres, Ahola, Tero
Published in Antimicrobial agents and chemotherapy (01.03.2017)
Published in Antimicrobial agents and chemotherapy (01.03.2017)
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Discovery of 3-phenyl- and 3-N-piperidinyl-isothiazolo[4,3-b]pyridines as highly potent inhibitors of cyclin G-associated kinase
Martinez-Gualda, Belén, Saul, Sirle, Froeyen, Mathy, Schols, Dominique, Herdewijn, Piet, Einav, Shirit, De Jonghe, Steven
Published in European journal of medicinal chemistry (05.03.2021)
Published in European journal of medicinal chemistry (05.03.2021)
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Identification and evaluation of 4-anilinoquin(az)olines as potent inhibitors of both dengue virus (DENV) and Venezuelan equine encephalitis virus (VEEV)
Saul, Sirle, Huang, Pei-Tzu, Einav, Shirit, Asquith, Christopher R.M.
Published in Bioorganic & medicinal chemistry letters (15.11.2021)
Published in Bioorganic & medicinal chemistry letters (15.11.2021)
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The cargo adapter protein CLINT1 is phosphorylated by the Numb-associated kinase BIKE and mediates dengue virus infection
Schor, Stanford, Pu, Szuyuan, Nicolaescu, Vlad, Azari, Siavash, Kõivomägi, Mardo, Karim, Marwah, Cassonnet, Patricia, Saul, Sirle, Neveu, Gregory, Yueh, Andrew, Demeret, Caroline, Skotheim, Jan M., Jacob, Yves, Randall, Glenn, Einav, Shirit
Published in The Journal of biological chemistry (01.06.2022)
Published in The Journal of biological chemistry (01.06.2022)
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Human parainfluenza virus 3 vaccine candidates attenuated by codon-pair deoptimization are immunogenic and protective in hamsters
Afroz, Sharmin, Saul, Sirle, Dai, Jin, Surman, Sonja, Liu, Xueqiao, Park, Hong-Su, Le Nouën, Cyril, Lingemann, Matthias, Dahal, Bibha, Coleman, John Robert, Mueller, Steffen, Collins, Peter Leon, Buchholz, Ursula Johanna, Munir, Shirin
Published in Proceedings of the National Academy of Sciences - PNAS (18.06.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (18.06.2024)
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