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Church, Rachel J., Kullak‐Ublick, Gerd A., Aubrecht, Jiri, Bonkovsky, Herbert L., Chalasani, Naga, Fontana, Robert J., Goepfert, Jens C., Hackman, Frances, King, Nicholas M. P., Kirby, Simon, Kirby, Patrick, Marcinak, John, Ormarsdottir, Sif, Schomaker, Shelli J., Schuppe‐Koistinen, Ina, Wolenski, Francis, Arber, Nadir, Merz, Michael, Sauer, John‐Michael, Andrade, Raul J., van Bömmel, Florian, Poynard, Thierry, Watkins, Paul B.
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Published in Hepatology (Baltimore, Md.) (01.02.2019)
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Serum glutamate dehydrogenase activity enables early detection of liver injury in subjects with underlying muscle impairments
Schomaker, Shelli, Potter, David, Warner, Roscoe, Larkindale, Jane, King, Nicholas, Porter, Amy C, Owens, Jane, Tomlinson, Lindsay, Sauer, John-Michael, Johnson, Kent, Aubrecht, Jiri
Published in PloS one (14.05.2020)
Published in PloS one (14.05.2020)
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Rat Urinary Osteopontin and Neutrophil Gelatinase-Associated Lipocalin Improve Certainty of Detecting Drug-Induced Kidney Injury
Phillips, Jonathan A, Holder, Daniel J, Ennulat, Daniela, Gautier, Jean-Charles, Sauer, John-Michael, Yang, Yi, McDuffie, Eric, Sonee, Manisha, Gu, Yi-Zhong, Troth, Sean P, Lynch, Karen, Hamlin, Diane, Peters, David G, Brees, Dominique, Walker, Elizabeth G
Published in Toxicological sciences (01.06.2016)
Published in Toxicological sciences (01.06.2016)
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Evaluation of the Relative Performance of Drug-Induced Skeletal Muscle Injury Biomarkers in Rats
Burch, Peter M, Greg Hall, David, Walker, Elizabeth G, Bracken, William, Giovanelli, Richard, Goldstein, Richard, Higgs, Richard E, King, Nicholas M P, Lane, Pamela, Sauer, John-Michael, Michna, Laura, Muniappa, Nagaraja, Pritt, Michael L, Vlasakova, Katerina, Watson, David E, Wescott, Debra, Zabka, Tanja S, Glaab, Warren E
Published in Toxicological sciences (01.03.2016)
Published in Toxicological sciences (01.03.2016)
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eTRANSAFE: Building a sustainable framework to share reproducible drug safety knowledge with the public domain [version 1; peer review: 2 approved]
Sarntivijai, Sirarat, Blomberg, Niklas, Lauer, Katharina B., Briggs, Katharine, Steger-Hartmann, Thomas, van der Lei, Johan, Sauer, John-Michael, Liwski, Richard, Mourby, Miranda, Camprubi, Montse
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Published in F1000 research (2022)
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Current state of cardiac troponin testing in Duchenne muscular dystrophy cardiomyopathy: review and recommendations from the Parent Project Muscular Dystrophy expert panel
Spurney, Christopher F, Ascheim, Deborah, Charnas, Lawrence, Cripe, Linda, Hor, Kan, King, Nicholas, Kinnett, Kathi, McNally, Elizabeth M, Sauer, John-Michael, Sweeney, Lee, Villa, Chet, Markham, Larry W
Published in Open heart (24.03.2021)
Published in Open heart (24.03.2021)
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Characterization of a Novel Endocannabinoid, Virodhamine, with Antagonist Activity at the CB1 Receptor
Porter, Amy C, Sauer, John-Michael, Knierman, Michael D, Becker, Gerald W, Berna, Michael J, Bao, Jingqi, Nomikos, George G, Carter, Petra, Bymaster, Frank P, Leese, Andrea Baker, Felder, Christian C
Published in The Journal of pharmacology and experimental therapeutics (01.06.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2002)
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A Formulation Strategy for Gamma Secretase Inhibitor ELND006, a BCS Class II Compound: Development of a Nanosuspension Formulation with Improved Oral Bioavailability and Reduced Food Effects in Dogs
Quinn, Kevin, Gullapalli, Rampurna Prasad, Merisko-liversidge, Elaine, Goldbach, Erich, Wong, Angelina, Liversidge, Gary G., Hoffman, Wherly, Sauer, John-michael, Bullock, John, Tonn, George
Published in Journal of pharmaceutical sciences (01.04.2012)
Published in Journal of pharmaceutical sciences (01.04.2012)
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Design and synthesis of a novel, orally active, brain penetrant, tri-substituted thiophene based JNK inhibitor
Bowers, Simeon, Truong, Anh P., Neitz, R. Jeffrey, Neitzel, Martin, Probst, Gary D., Hom, Roy K., Peterson, Brian, Galemmo, Robert A., Konradi, Andrei W., Sham, Hing L., Tóth, Gergley, Pan, Hu, Yao, Nanhua, Artis, Dean R., Brigham, Elizabeth F., Quinn, Kevin P., Sauer, John-Michael, Powell, Kyle, Ruslim, Lany, Ren, Zhao, Bard, Frédérique, Yednock, Ted A., Griswold-Prenner, Irene
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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Taxines: a review of the mechanism and toxicity of yew ( Taxus spp.) alkaloids
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Disposition and Metabolic Fate of Atomoxetine Hydrochloride: The Role of CYP2D6 in Human Disposition and Metabolism
SAUER, John-Michael, PONSLER, G. Douglas, MATTIUZ, Edward L, LONG, Amanda J, WITCHER, Jennifer W, THOMASSON, Holly R, DESANTE, Karl A
Published in Drug metabolism and disposition (01.01.2003)
Published in Drug metabolism and disposition (01.01.2003)
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Sauer, John-Michael, Porter, Amy C
Published in Experimental biology and medicine (Maywood, N.J.) (01.02.2018)
Published in Experimental biology and medicine (Maywood, N.J.) (01.02.2018)
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Design and synthesis of cell potent BACE-1 inhibitors: Structure–activity relationship of P1′ substituents
Sealy, Jennifer M., Truong, Anh P., Tso, Luke, Probst, Gary D., Aquino, Jose, Hom, Roy K., Jagodzinska, Barbara M., Dressen, Darren, Wone, David W.G., Brogley, Louis, John, Varghese, Tung, Jay S., Pleiss, Michael A., Tucker, John A., Konradi, Andrei W., Dappen, Michael S., Toth, Gergely, Pan, Hu, Ruslim, Lany, Miller, Jim, Bova, Michael P., Sinha, Sukanto, Quinn, Kevin P., Sauer, John-Michael
Published in Bioorganic & medicinal chemistry letters (15.11.2009)
Published in Bioorganic & medicinal chemistry letters (15.11.2009)
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Atomoxetine pharmacokinetics in children and adolescents with attention deficit hyperactivity disorder
Witcher, Jennifer W, Long, Amanda, Smith, Brian, Sauer, John-Michael, Heilgenstein, John, Wilens, Timothy, Spencer, Thomas, Biederman, Joseph
Published in Journal of child and adolescent psychopharmacology (01.03.2003)
Published in Journal of child and adolescent psychopharmacology (01.03.2003)
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What evidence do we need for biomarker qualification?
Leptak, Chris, Menetski, Joseph P, Wagner, John A, Aubrecht, Jiri, Brady, Linda, Brumfield, Martha, Chin, William W, Hoffmann, Steve, Kelloff, Gary, Lavezzari, Gabriela, Ranganathan, Rajesh, Sauer, John-Michael, Sistare, Frank D, Zabka, Tanja, Wholley, David
Published in Science translational medicine (22.11.2017)
Published in Science translational medicine (22.11.2017)
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Effect of hepatic impairment on the pharmacokinetics of atomoxetine and its metabolites
Chalon, Stephan A, Desager, Jean-Pierre, Desante, Karl A, Frye, Reginald F, Witcher, Jennifer, Long, Amanda J, Sauer, John-Michael, Golnez, Jean-Luc, Smith, Brian P, Thomasson, Holly R, Horsmans, Yves
Published in Clinical pharmacology and therapeutics (01.03.2003)
Published in Clinical pharmacology and therapeutics (01.03.2003)
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Net Reclassification Index and Integrated Discrimination Index Are Not Appropriate for Testing Whether a Biomarker Improves Predictive Performance
Burch, Peter M, Glaab, Warren E, Holder, Daniel J, Phillips, Jonathan A, Sauer, John-Michael, Walker, Elizabeth G
Published in Toxicological sciences (01.03.2017)
Published in Toxicological sciences (01.03.2017)
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