Irinotecan, a key chemotherapeutic drug for metastatic colorectal cancer
Fujita, Ken-ichi, Kubota, Yutaro, Ishida, Hiroo, Sasaki, Yasutsuna
Published in World journal of gastroenterology : WJG (21.11.2015)
Published in World journal of gastroenterology : WJG (21.11.2015)
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Distinct Afatinib Resistance Mechanisms Identified in Lung Adenocarcinoma Harboring an EGFR Mutation
Yamaoka, Toshimitsu, Ohmori, Tohru, Ohba, Motoi, Arata, Satoru, Murata, Yasunori, Kusumoto, Sojiro, Ando, Koichi, Ishida, Hiroo, Ohnishi, Tsukasa, Sasaki, Yasutsuna
Published in Molecular cancer research (01.07.2017)
Published in Molecular cancer research (01.07.2017)
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Phase II trial of nanoparticle albumin‐bound paclitaxel as second‐line chemotherapy for unresectable or recurrent gastric cancer
Sasaki, Yasutsuna, Nishina, Tomohiro, Yasui, Hirofumi, Goto, Masahiro, Muro, Kei, Tsuji, Akihito, Koizumi, Wasaburo, Toh, Yasushi, Hara, Takuo, Miyata, Yoshinori
Published in Cancer science (01.07.2014)
Published in Cancer science (01.07.2014)
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Leucovorin, fluorouracil, and oxaliplatin plus bevacizumab versus S-1 and oxaliplatin plus bevacizumab in patients with metastatic colorectal cancer (SOFT): an open-label, non-inferiority, randomised phase 3 trial
Yamada, Yasuhide, Dr, Takahari, Daisuke, MD, Matsumoto, Hiroshi, MD, Baba, Hideo, Prof, Nakamura, Masato, MD, Yoshida, Kazuhiro, Prof, Yoshida, Motoki, MD, Iwamoto, Shigeyoshi, MD, Shimada, Ken, MD, Komatsu, Yoshito, MD, Sasaki, Yasutsuna, Prof, Satoh, Taroh, MD, Takahashi, Keiichi, MD, Mishima, Hideyuki, Prof, Muro, Kei, MD, Watanabe, Masahiko, Prof, Sakata, Yuh, MD, Morita, Satoshi, Prof, Shimada, Yasuhiro, MD, Sugihara, Kenichi, Prof
Published in The lancet oncology (01.12.2013)
Published in The lancet oncology (01.12.2013)
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Minimal contribution of the hepatic uptake transporter OATP1B1 to the inter-individual variability in SN-38 pharmacokinetics in cancer patients without severe renal failure
Tsuboya, Ayako, Kubota, Yutaro, Ishida, Hiroo, Ohkuma, Ryotaro, Ishiguro, Tomoyuki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Tsunoda, Takuya, Sasaki, Yasutsuna, Matsumoto, Natsumi, Kondo, Yusuke, Tomoda, Yukana, Kusuhara, Hiroyuki, Fujita, Ken-ichi
Published in Cancer chemotherapy and pharmacology (01.09.2021)
Published in Cancer chemotherapy and pharmacology (01.09.2021)
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Lack of correlation between the costs of anticancer drugs and clinical benefits in Japan
Satoh, Etsuko, Sasaki, Yasutsuna, Ohkuma, Ryotaro, Takahashi, Takehiro, Kubota, Yutaro, Ishida, Hiroo, Hamada, Kazuyuki, Kiuchi, Yuji, Tsunoda, Takuya
Published in Cancer science (01.12.2018)
Published in Cancer science (01.12.2018)
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Nationwide prospective and retrospective surveys for hepatitis B virus reactivation during immunosuppressive therapies
Mochida, Satoshi, Nakao, Masamitsu, Nakayama, Nobuaki, Uchida, Yoshihito, Nagoshi, Sumiko, Ido, Akio, Mimura, Toshihide, Harigai, Masayoshi, Kaneko, Hiroshi, Kobayashi, Hiroko, Tsuchida, Tetsuya, Suzuki, Hiromichi, Ura, Nobuyuki, Nakamura, Yuichi, Bessho, Masami, Dan, Kazuo, Kusumoto, Shigeru, Sasaki, Yasutsuna, Fujii, Hirofumi, Suzuki, Fumitaka, Ikeda, Kenji, Yamamoto, Kazuhiko, Takikawa, Hajime, Tsubouchi, Hirohito, Mizokami, Masashi
Published in Journal of gastroenterology (01.10.2016)
Published in Journal of gastroenterology (01.10.2016)
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Influx and Efflux Transporters Contribute to the Increased Dermal Exposure to Active Metabolite of Regorafenib After Repeated Oral Administration in Mice
Al-Shammari, Aya Hasan, Masuo, Yusuke, Fujita, Ken-ichi, Yoshikawa, Yuka, Nakamichi, Noritaka, Kubota, Yutaro, Sasaki, Yasutsuna, Kato, Yukio
Published in Journal of pharmaceutical sciences (01.06.2019)
Published in Journal of pharmaceutical sciences (01.06.2019)
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Pharmacokinetics of gefitinib in elderly patients with EGFR-mutated advanced non-small cell lung cancer: a prospective study
Nio, Yuta, Ishida, Hiroo, Matsumoto, Natsumi, Kusumoto, Sojiro, Kubota, Yutaro, Tsunoda, Takuya, Sasaki, Yasutsuna, Fujita, Ken-Ichi
Published in BMC pulmonary medicine (30.11.2022)
Published in BMC pulmonary medicine (30.11.2022)
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Organic Cation Transporter 1 Is Responsible for Hepatocellular Uptake of the Tyrosine Kinase Inhibitor Pazopanib
Ellawatty, Waleed Elsayed Ahmed, Masuo, Yusuke, Fujita, Ken-Ichi, Yamazaki, Erina, Ishida, Hiroo, Arakawa, Hiroshi, Nakamichi, Noritaka, Abdelwahed, Ramadan, Sasaki, Yasutsuna, Kato, Yukio
Published in Drug metabolism and disposition (01.01.2018)
Published in Drug metabolism and disposition (01.01.2018)
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Randomized phase II trial of nimotuzumab plus irinotecan versus irinotecan alone as second-line therapy for patients with advanced gastric cancer
Satoh, Taroh, Lee, Kyung Hee, Rha, Sun Young, Sasaki, Yasutsuna, Park, Se Hoon, Komatsu, Yoshito, Yasui, Hirofumi, Kim, Tae-You, Yamaguchi, Kensei, Fuse, Nozomu, Yamada, Yasuhide, Ura, Takashi, Kim, Si-Young, Munakata, Masaki, Saitoh, Soh, Nishio, Kazuto, Morita, Satoshi, Yamamoto, Eriko, Zhang, Qingwei, Kim, Jung-mi, Kim, Yeul Hong, Sakata, Yuh
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.10.2015)
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.10.2015)
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Acquired Resistance Mechanisms to Combination Met-TKI/EGFR-TKI Exposure in Met-Amplified EGFR-TKI-Resistant Lung Adenocarcinoma Harboring an Activating EGFR Mutation
Yamaoka, Toshimitsu, Ohmori, Tohru, Ohba, Motoi, Arata, Satoru, Kishino, Yasunari, Murata, Yasunori, Kusumoto, Sojiro, Ishida, Hiroo, Shirai, Takao, Hirose, Takashi, Ohnishi, Tsukasa, Sasaki, Yasutsuna
Published in Molecular cancer therapeutics (01.12.2016)
Published in Molecular cancer therapeutics (01.12.2016)
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Genotype‐directed, dose‐finding study of irinotecan in cancer patients with UGT1A128 and/or UGT1A16 polymorphisms
Satoh, Taroh, Ura, Takashi, Yamada, Yasuhide, Yamazaki, Kentaro, Tsujinaka, Toshimasa, Munakata, Masaki, Nishina, Tomohiro, Okamura, Shu, Esaki, Taito, Sasaki, Yasutsuna, Koizumi, Wasaburo, Kakeji, Yoshihiro, Ishizuka, Naoki, Hyodo, Ichinosuke, Sakata, Yuh
Published in Cancer science (01.10.2011)
Published in Cancer science (01.10.2011)
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Direct Inhibition and Down-regulation by Uremic Plasma Components of Hepatic Uptake Transporter for SN-38, an Active Metabolite of Irinotecan, in Humans
Fujita, Ken-ichi, Sugiura, Tomoko, Okumura, Hidenori, Umeda, Saki, Nakamichi, Noritaka, Watanabe, Yusuke, Suzuki, Hiromichi, Sunakawa, Yu, Shimada, Ken, Kawara, Kaori, Sasaki, Yasutsuna, Kato, Yukio
Published in Pharmaceutical research (01.01.2014)
Published in Pharmaceutical research (01.01.2014)
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Patritumab plus trastuzumab and paclitaxel in human epidermal growth factor receptor 2‐overexpressing metastatic breast cancer
Mukai, Hirofumi, Saeki, Toshiaki, Aogi, Kenjiro, Naito, Yoichi, Matsubara, Nobuaki, Shigekawa, Takashi, Ueda, Shigeto, Takashima, Seiki, Hara, Fumikata, Yamashita, Tomonari, Ohwada, Shoichi, Sasaki, Yasutsuna
Published in Cancer science (01.10.2016)
Published in Cancer science (01.10.2016)
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Journal Article
Sorafenib and Sunitinib, Two Anticancer Drugs, Inhibit CYP3A4-Mediated and Activate CY3A5-Mediated Midazolam 1'-Hydroxylation
SUGIYAMA, Minako, FUJITA, Ken-Ichi, MURAYAMA, Norie, AKIYAMA, Yuko, YAMAZAKI, Hiroshi, SASAKI, Yasutsuna
Published in Drug metabolism and disposition (01.05.2011)
Published in Drug metabolism and disposition (01.05.2011)
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