Direct arylation of strong aliphatic C–H bonds
Perry, Ian B., Brewer, Thomas F., Sarver, Patrick J., Schultz, Danielle M., DiRocco, Daniel A., MacMillan, David W. C.
Published in Nature (London) (01.08.2018)
Published in Nature (London) (01.08.2018)
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Journal Article
The merger of decatungstate and copper catalysis to enable aliphatic C(sp3)–H trifluoromethylation
Sarver, Patrick J., Bacauanu, Vlad, Schultz, Danielle M., DiRocco, Daniel A., Lam, Yu-hong, Sherer, Edward C., MacMillan, David W. C.
Published in Nature chemistry (01.05.2020)
Published in Nature chemistry (01.05.2020)
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Journal Article
Tunable Low–Relative Humidity and High–Capacity Water Adsorption in a Bibenzotriazole Metal–Organic Framework
Alezi, Dalal, Oppenheim, Julius J., Sarver, Patrick J., Iliescu, Andrei, Dinakar, Bhavish, Dincă, Mircea
Published in Journal of the American Chemical Society (22.11.2023)
Published in Journal of the American Chemical Society (22.11.2023)
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Journal Article
Photoredox Catalysis-Enabled Sulfination of Alcohols and Bromides
Carson II, William P., Sarver, Patrick J., Goudy, Noelle S., MacMillan, David W. C.
Published in Journal of the American Chemical Society (27.09.2023)
Published in Journal of the American Chemical Society (27.09.2023)
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Journal Article
Plasmon Mediated Near‐Field Energy Transfer From Solid‐State, Electrically Injected Excitons to Solution Phase Chromophores
Wisch, Jesse A., Liu, Xiao, Sarver, Patrick J., Kullmer, Cesar N. Prieto, Millet, Agustin, MacMillan, David W. C., Rand, Barry P.
Published in Advanced functional materials (01.06.2023)
Published in Advanced functional materials (01.06.2023)
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Journal Article
Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer
LaMarche, Matthew J, Acker, Michael, Argintaru, Andreea, Bauer, Daniel, Boisclair, Julie, Chan, Homan, Chen, Christine Hiu-Tung, Chen, Ying-Nan, Chen, Zhouliang, Deng, Zhan, Dore, Michael, Dunstan, David, Fan, Jianmei, Fekkes, Peter, Firestone, Brant, Fodor, Michelle, Garcia-Fortanet, Jorge, Fortin, Pascal D, Fridrich, Cary, Giraldes, John, Glick, Meir, Grunenfelder, Denise, Hao, Huia-Xiang, Hentemann, Martin, Ho, Samuel, Jouk, Andriana, Kang, Zhao B, Karki, Rajesh, Kato, Mitsunori, Keen, Nick, Koenig, Robert, LaBonte, Laura R, Larrow, Jay, Liu, Gang, Liu, Shumei, Majumdar, Dyuti, Mathieu, Simon, Meyer, Matthew J, Mohseni, Morvarid, Ntaganda, Rukundo, Palermo, Mark, Perez, Lawrence, Pu, Minying, Ramsey, Timothy, Reilly, John, Sarver, Patrick, Sellers, William R, Sendzik, Martin, Shultz, Michael D, Slisz, Joanna, Slocum, Kelly, Smith, Troy, Spence, Stanley, Stams, Travis, Straub, Christopher, Tamez, Victoriano, Toure, Bakary-Barry, Towler, Christopher, Wang, Ping, Wang, Hongyun, Williams, Sarah L, Yang, Fan, Yu, Bing, Zhang, Ji-Hu, Zhu, Suzanne
Published in Journal of medicinal chemistry (25.11.2020)
Published in Journal of medicinal chemistry (25.11.2020)
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Journal Article
6‑Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors
Sarver, Patrick, Acker, Michael, Bagdanoff, Jeffrey T, Chen, Zhouliang, Chen, Ying-Nan, Chan, Homan, Firestone, Brant, Fodor, Michelle, Fortanet, Jorge, Hao, Huaixiang, Hentemann, Murphy, Kato, Mitsunori, Koenig, Robert, LaBonte, Laura R, Liu, Gang, Liu, Shumei, Liu, Chen, McNeill, Eric, Mohseni, Morvarid, Sendzik, Martin, Stams, Travis, Spence, Stan, Tamez, Victoriano, Tichkule, Ritesh, Towler, Christopher, Wang, Hongyun, Wang, Ping, Williams, Sarah L, Yu, Bing, LaMarche, Matthew J
Published in Journal of medicinal chemistry (28.02.2019)
Published in Journal of medicinal chemistry (28.02.2019)
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Journal Article
Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors
Bagdanoff, Jeffrey T, Chen, Zhouliang, Acker, Michael, Chen, Ying-Nan, Chan, Homan, Dore, Michael, Firestone, Brant, Fodor, Michelle, Fortanet, Jorge, Hentemann, Murphy, Kato, Mitsunori, Koenig, Robert, LaBonte, Laura R, Liu, Shumei, Mohseni, Movarid, Ntaganda, Rukundo, Sarver, Patrick, Smith, Troy, Sendzik, Martin, Stams, Travis, Spence, Stan, Towler, Christopher, Wang, Hongyun, Wang, Ping, Williams, Sarah L, LaMarche, Matthew J
Published in Journal of medicinal chemistry (28.02.2019)
Published in Journal of medicinal chemistry (28.02.2019)
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Journal Article
Abstract LB-005: Allosteric SHP2 phosphatase inhibition: Multiple mechanisms and chemotypes
LaMarche, Matthew J., Bagdanoff, Jeff, Acker, Mike, Chen, Ying-Nan, Chan, Homan, Dore, Michael, Firestone, Brant, Fodor, Michelle, Garcia-Fortanet, Jorge, Hentemann, Murphy, Kato, Mitsunori, Koenig, Robert, Bonte, Laura La, Liu, Shumei, Mohseni, Movarid, Ntaganda, Rukundo, Sarver, Patrick, Smith, Troy, Sendzik, Martin, Stams, Travis, Spence, Stan, Towler, Chris, Wang, Hongyun, Wang, Ping, Williams, Sarah, Chen, Zhouliang, Hao, Huaixiang, Liu, Gang, Liu, Chen, McNeill, Eric, Yu, Bing
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Correction to Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors
Bagdanoff, Jeffrey T, Chen, Zhouliang, Acker, Michael, Chen, Ying-Nan, Chan, Homan, Dore, Michael, Firestone, Brant, Fodor, Michelle, Fortanet, Jorge, Hentemann, Murphy, Kato, Mitsunori, Koenig, Robert, LaBonte, Laura R, Liu, Shumei, Mohseni, Movarid, Ntaganda, Rukundo, Sarver, Patrick, Shultz, Michael D, Smith, Troy, Sendzik, Martin, Stams, Travis, Spence, Stan, Towler, Christopher, Wang, Hongyun, Wang, Ping, Williams, Sarah L, LaMarche, Matthew J
Published in Journal of medicinal chemistry (11.04.2019)
Published in Journal of medicinal chemistry (11.04.2019)
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Journal Article
Correction to 6‑Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors
Sarver, Patrick, Acker, Michael, Bagdanoff, Jeffrey T, Chen, Zhouliang, Chen, Ying-Nan, Chan, Homan, Firestone, Brant, Fodor, Michelle, Fortanet, Jorge, Hao, Huaixiang, Hentemann, Murphy, Jouk, Andriana, Kato, Mitsunori, Koenig, Robert, LaBonte, Laura R, Liu, Gang, Liu, Shumei, Liu, Chen, McNeill, Eric, Mohseni, Morvarid, Shultz, Michael D, Sendzik, Martin, Stams, Travis, Spence, Stan, Tamez, Victoriano, Tichkule, Ritesh, Towler, Christopher, Wang, Hongyun, Wang, Ping, Williams, Sarah L, Yu, Bing, LaMarche, Matthew J
Published in Journal of medicinal chemistry (11.04.2019)
Published in Journal of medicinal chemistry (11.04.2019)
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Journal Article
키나제 억제제로서의 트리시클릭 화합물 및 조성물
RAUNIYAR VIVEK, AVERSA ROBERT JOHN, DILLON MICHAEL PATRICK, ROBINSON RICHARD, BURGER MATTHEW T, SARVER PATRICK JAMES, DINEEN JR. THOMAS A, RAMURTHY SAVITHRI, KARKI RAJESH
Year of Publication 27.08.2018
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Year of Publication 27.08.2018
Patent
COMPOUNDS AND COMPOSITIONS FOR INHBITING THE ACTIVITY OF SHP2
Bagdanoff, Jeffrey T, Kato, Mitsunori, Williams, Sarah, Dore, Michael, LaMarche, Matthew J, Smith, Troy Douglas, Sarver, Patrick James, Fortanet, Jorge Garcia, Chen, Zhuoliang, Shultz, Michael
Year of Publication 24.03.2022
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Year of Publication 24.03.2022
Patent
COMPOUNDS AND COMPOSITIONS FOR INHBITING THE ACTIVITY OF SHP2
Bagdanoff, Jeffrey T, Kato, Mitsunori, Williams, Sarah, Dore, Michael, LaMarche, Matthew J, Smith, Troy Douglas, Sarver, Patrick James, Fortanet, Jorge Garcia, Chen, Zhuoliang, Shultz, Michael
Year of Publication 07.10.2021
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Year of Publication 07.10.2021
Patent
Compounds and compositions for inhibiting the activity of SHP2
Bagdanoff, Jeffrey T, Kato, Mitsunori, Williams, Sarah, Dore, Michael, LaMarche, Matthew J, Smith, Troy Douglas, Sarver, Patrick James, Fortanet, Jorge Garcia, Chen, Zhuoliang, Shultz, Michael
Year of Publication 13.04.2021
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Year of Publication 13.04.2021
Patent
COMPOUNDS AND COMPOSITIONS FOR INHBITING THE ACTIVITY OF SHP2
Bagdanoff, Jeffrey T, Kato, Mitsunori, Williams, Sarah, Dore, Michael, LaMarche, Matthew J, Smith, Troy Douglas, Sarver, Patrick James, Fortanet, Jorge Garcia, Chen, Zhuoliang, Shultz, Michael
Year of Publication 20.06.2019
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Year of Publication 20.06.2019
Patent