Human epidermal growth factor receptor (HER-1:HER-3) Fc-mediated heterodimer has broad antiproliferative activity in vitro and in human tumor xenografts
Sarup, Jay, Jin, Pei, Turin, Lisa, Bai, Xiaomei, Beryt, Malgorzata, Brdlik, Cathleen, Higaki, Jeffrey N, Jorgensen, Brett, Lau, Francis W, Lindley, Peter, Liu, Jim, Ni, Irene, Rozzelle, James, Kumari, Rajendra, Watson, Susan A, Zhang, Juan, Shepard, H Michael
Published in Molecular cancer therapeutics (01.10.2008)
Published in Molecular cancer therapeutics (01.10.2008)
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Journal Article
5,7-Dimethoxy-3-(4-Pyridinyl)Quinoline Is a Potent and Selective Inhibitor of Human Vascular .beta.-Type Platelet-Derived Growth Factor Receptor Tyrosine Kinase
Dolle, Roland E, Dunn, Joseph A, Bobko, Mark, Singh, Baldev, Kuster, Joan E, Baizman, Eugene, Harris, Alex L, Sawutz, David G, Miller, Deborah, Wang, Su, Faltynek, Connie R, Xie, Wen, Sarup, Jay, Bode, D. Christopher, Pagani, Edward D, Silver, Paul J
Published in Journal of medicinal chemistry (19.08.1994)
Published in Journal of medicinal chemistry (19.08.1994)
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Journal Article
Monoclonal antibody therapy of human cancer: taking the HER2 protooncogene to the clinic
Shepard, H M, Lewis, G D, Sarup, J C, Fendly, B M, Maneval, D, Mordenti, J, Figari, I, Kotts, C E, Palladino, Jr, M A, Ullrich, A
Published in Journal of clinical immunology (01.05.1991)
Published in Journal of clinical immunology (01.05.1991)
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Journal Article
Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu
Benz, C C, Scott, G K, Sarup, J C, Johnson, R M, Tripathy, D, Coronado, E, Shepard, H M, Osborne, C K
Published in Breast cancer research and treatment (01.01.1992)
Published in Breast cancer research and treatment (01.01.1992)
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Journal Article
CATALYTIC DOMAIN OF THE HUMAN EFFECTOR CELL CYCLE CHECKPOINT PROTEIN KINASE, CHK1, MATERIALS AND METHOD FOR IDENTIFICATION OF INHIBITORS THEREOF
KAN CHENN, NGUYEN BINH, SARUP JAY CHAND, REGISTER JAMES, CHEN PING, LUNDGREN KAREN, LUO CHUN, ANDERSON MARK BRIAN, GAUR SMITA, MARGOSIAK STEPHEN, TEMPCZYK-RUSSEL ANNA, DENG YA-LI, O'CONNOR PATRICK
Year of Publication 25.06.2001
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Year of Publication 25.06.2001
Patent
Direct Interaction of a Ligand for the erb B2 Oncogene Product with the EGF Receptor and p185 erb B2
Lupu, Ruth, Colomer, Ramon, Zugmaier, Gerhard, Sarup, Jay, Shepard, Michael, Slamon, Dennis, Lippman, Marc E.
Published in Science (American Association for the Advancement of Science) (28.09.1990)
Published in Science (American Association for the Advancement of Science) (28.09.1990)
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Journal Article
Direct Interaction of a Ligand for the erbB2 Oncogene Product with the EGF Receptor and p185$^{erbB2}
Lupu, Ruth, Colomer, Ramon, Zugmaier, Gerhard, Sarup, Jay, Shepard, Michael, Slamon, Dennis, Lippman, Marc E.
Published in Science (American Association for the Advancement of Science) (28.09.1990)
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Published in Science (American Association for the Advancement of Science) (28.09.1990)
Journal Article
Regulation of purine deoxynucleoside phosphorylation by deoxycytidine kinase from human leukemic blast cells
Sarup, J C, Johnson, M A, Verhoef, V, Fridland, A
Published in Biochemical pharmacology (15.08.1989)
Published in Biochemical pharmacology (15.08.1989)
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Journal Article
Catalytic domains of the human hepatocyte growth factor receptor tyrosine kinase, and materials and methods for identification of inhibitors thereof
MURRAY BRION WILLIAM, SARUP JAY, MCTIGUE MICHELE ANN, PARGE HANS, MROCZKOWSKI BARBARA, HICKEY MICHAEL, ZHU JEFF
Year of Publication 15.01.2004
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Year of Publication 15.01.2004
Patent
Catalytic domains of the human hepatocyte growth factor receptor tyrosine kinase, and materials and methods for identification of inhibitors thereof
Hickey, Michael, Mroczkowski, Barbara, McTigue, Michele, Murray, Brion, Parge, Hans, Sarup, Jay, Zhu, Jeff
Year of Publication 15.01.2004
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Year of Publication 15.01.2004
Patent
Catalytic domains of the human hepatocyte growth factor receptor tyrosine kinase and methods for identification of inhibitors thereof
ZHU, JEFF, PARGE, HANS, SARUP, JAY, MCTIGUE, MICHELE ANN, HICKEY, MICHAEL, MURRAY, BRION WILLIAM, MROCZKOWSKI, BARBARA
Year of Publication 12.02.2003
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Year of Publication 12.02.2003
Patent
CATALYST DOMAIN OF HUMAN HEPATOCYTE GROWTH FACTOR RECEPTOR TYROSINE KINASE, SUBSTANCE ACTING AS INHIBITOR OF THE DOMAIN AND METHOD FOR IDENTIFICATION OF THE INHIBITOR
MURRAY BRION WILLIAM, SARUP JAY, MCTIGUE MICHELE ANN, PARGE HANS, MROCZKOWSKI BARBARA, HICKEY MICHAEL, ZHU JEFF
Year of Publication 14.01.2003
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Year of Publication 14.01.2003
Patent
Catalytic domains of the human hepatocyte growth factor receptor tyrosine kinase and methods for identification of inhibitors thereof
ZHU, JEFF, PARGE, HANS, SARUP, JAY, MCTIGUE, MICHELE ANN, HICKEY, MICHAEL, MURRAY, BRION WILLIAM, MROCZKOWSKI, BARBARA
Year of Publication 25.09.2002
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Year of Publication 25.09.2002
Patent
CATALYTIC DOMAINS OF THE HUMAN HEPATOCYTE GROWTH FACTOR RECEPTOR TYROSINE KINASE, AND MATERIALS AND METHODS FOR IDENTIFICATION OF INHIBITORS THEREOF
ZHU, JEFF, SARUP, JAY, PARGE, HANS, MCTIGUE, MICHELE ANN, HICKEY, MICHAEL, MURRAY, BRION WILLIAM, MROCZKOWSKI, BARBARA
Year of Publication 23.09.2002
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Year of Publication 23.09.2002
Patent
Katalytische Domäne der menschlichen Effektor Zellzyklus Kontrollpunkt-proteinkinase Chk1, Materialien und Verfahren zur Identifizierung von Inhibitoren davon
SARUP, JAY CHAND, DENG, YA-LI, ANDERSON, MARK BRIAN, LUNDGREN, KAREN, GAUR, SMITA, O'CONNOR, PATRICK, REGISTER, JAMES, MARGOSIAK, STEPHEN, NGUYEN, BINH, CHEN, PING, LUO, CHUN, TEMPCZYK-RUSSEL, ANNA, KAN, KECK
Year of Publication 23.08.2007
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Year of Publication 23.08.2007
Patent