RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection
Chapman, J. Ross, Barral, Patricia, Vannier, Jean-Baptiste, Borel, Valérie, Steger, Martin, Tomas-Loba, Antonia, Sartori, Alessandro A., Adams, Ian R., Batista, Facundo D., Boulton, Simon J.
Published in Molecular cell (07.03.2013)
Published in Molecular cell (07.03.2013)
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Noncanonical Mismatch Repair as a Source of Genomic Instability in Human Cells
Peña-Diaz, Javier, Bregenhorn, Stephanie, Ghodgaonkar, Medini, Follonier, Cindy, Artola-Borán, Mariela, Castor, Dennis, Lopes, Massimo, Sartori, Alessandro A., Jiricny, Josef
Published in Molecular cell (14.09.2012)
Published in Molecular cell (14.09.2012)
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CDK targets Sae2 to control DNA-end resection and homologous recombination
Sartori, Alessandro A, Aguilera, Andrés, Cortés-Ledesma, Felipe, Huertas, Pablo, Jackson, Stephen P
Published in Nature (02.10.2008)
Published in Nature (02.10.2008)
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Deficiency in Homologous Recombination Renders Mammalian Cells More Sensitive to Proton Versus Photon Irradiation
Grosse, Nicole, PhD, Fontana, Andrea O., MSc, Hug, Eugen B., MD, Lomax, Antony, PhD, Coray, Adolf, PhD, Augsburger, Marc, MSc, Paganetti, Harald, PhD, Sartori, Alessandro A., PhD, Pruschy, Martin, PhD
Published in International journal of radiation oncology, biology, physics (2014)
Published in International journal of radiation oncology, biology, physics (2014)
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Journal Article
Differential DNA repair pathway choice in cancer cells after proton- and photon-irradiation
Fontana, Andrea O, Augsburger, Marc A, Grosse, Nicole, Guckenberger, Matthias, Lomax, Anthony J, Sartori, Alessandro A, Pruschy, Martin N
Published in Radiotherapy and oncology (01.09.2015)
Published in Radiotherapy and oncology (01.09.2015)
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Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells
Toller, Isabella M, Neelsen, Kai J, Steger, Martin, Hartung, Mara L, Hottiger, Michael O, Stucki, Manuel, Kalali, Behnam, Gerhard, Markus, Sartori, Alessandro A, Lopes, Massimo, Müller, Anne
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2011)
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Deficiency of FANCD2-Associated Nuclease KIAA1018/FAN1 Sensitizes Cells to Interstrand Crosslinking Agents
Kratz, Katja, Schöpf, Barbara, Kaden, Svenja, Sendoel, Ataman, Eberhard, Ralf, Lademann, Claudio, Cannavó, Elda, Sartori, Alessandro A., Hengartner, Michael O., Jiricny, Josef
Published in Cell (09.07.2010)
Published in Cell (09.07.2010)
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Journal Article
FANCD2 and CtIP Cooperate to Repair DNA Interstrand Crosslinks
Murina, Olga, von Aesch, Christine, Karakus, Ufuk, Ferretti, Lorenza P., Bolck, Hella A., Hänggi, Kay, Sartori, Alessandro A.
Published in Cell reports (Cambridge) (01.05.2014)
Published in Cell reports (Cambridge) (01.05.2014)
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FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington’s disease
Goold, Robert, Hamilton, Joseph, Menneteau, Thomas, Flower, Michael, Bunting, Emma L., Aldous, Sarah G., Porro, Antonio, Vicente, José R., Allen, Nicholas D., Wilkinson, Hilary, Bates, Gillian P., Sartori, Alessandro A., Thalassinos, Konstantinos, Balmus, Gabriel, Tabrizi, Sarah J.
Published in Cell reports (Cambridge) (31.08.2021)
Published in Cell reports (Cambridge) (31.08.2021)
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γ-Radiation promotes immunological recognition of cancer cells through increased expression of cancer-testis antigens in vitro and in vivo
Sharma, Anu, Bode, Beata, Wenger, Roland H, Lehmann, Kuno, Sartori, Alessandro A, Moch, Holger, Knuth, Alexander, Boehmer, Lotta von, Broek, Maries van den
Published in PloS one (29.11.2011)
Published in PloS one (29.11.2011)
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FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2
Porro, Antonio, Berti, Matteo, Pizzolato, Julia, Bologna, Serena, Kaden, Svenja, Saxer, Anja, Ma, Yue, Nagasawa, Kazuo, Sartori, Alessandro A., Jiricny, Josef
Published in Nature communications (20.10.2017)
Published in Nature communications (20.10.2017)
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Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resection
Ferretti, Lorenza P., Himmels, Sarah-Felicitas, Trenner, Anika, Walker, Christina, von Aesch, Christine, Eggenschwiler, Aline, Murina, Olga, Enchev, Radoslav I., Peter, Matthias, Freire, Raimundo, Porro, Antonio, Sartori, Alessandro A.
Published in Nature communications (26.08.2016)
Published in Nature communications (26.08.2016)
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FANCD2-Associated Nuclease 1 Partially Compensates for the Lack of Exonuclease 1 in Mismatch Repair
Kratz, Katja, Artola-Borán, Mariela, Kobayashi-Era, Saho, Koh, Gene, Oliveira, Goncalo, Kobayashi, Shunsuke, Oliveira, Andreia, Zou, Xueqing, Richter, Julia, Tsuda, Masataka, Sasanuma, Hiroyuki, Takeda, Shunichi, Loizou, Joanna I., Sartori, Alessandro A., Nik-Zainal, Serena, Jiricny, Josef
Published in Molecular and cellular biology (01.09.2021)
Published in Molecular and cellular biology (01.09.2021)
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H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours
Dibitetto, Diego, Liptay, Martin, Vivalda, Francesca, Dogan, Hülya, Gogola, Ewa, González Fernández, Martín, Duarte, Alexandra, Schmid, Jonas A., Decollogny, Morgane, Francica, Paola, Przetocka, Sara, Durant, Stephen T., Forment, Josep V., Klebic, Ismar, Siffert, Myriam, de Bruijn, Roebi, Kousholt, Arne N., Marti, Nicole A., Dettwiler, Martina, Sørensen, Claus S., Tille, Jean-Christophe, Undurraga, Manuela, Labidi-Galy, Intidhar, Lopes, Massimo, Sartori, Alessandro A., Jonkers, Jos, Rottenberg, Sven
Published in Nature communications (24.05.2024)
Published in Nature communications (24.05.2024)
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Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining
Francica, Paola, Mutlu, Merve, Blomen, Vincent A., Oliveira, Catarina, Nowicka, Zuzanna, Trenner, Anika, Gerhards, Nora M., Bouwman, Peter, Stickel, Elmer, Hekkelman, Maarten L., Lingg, Lea, Klebic, Ismar, van de Ven, Marieke, de Korte-Grimmerink, Renske, Howald, Denise, Jonkers, Jos, Sartori, Alessandro A., Fendler, Wojciech, Chapman, J. Ross, Brummelkamp, Thijn, Rottenberg, Sven
Published in Cell reports (Cambridge) (25.08.2020)
Published in Cell reports (Cambridge) (25.08.2020)
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Journal Article
Controlling DNA-end resection: a new task for CDKs
Ferretti, Lorenza P, Lafranchi, Lorenzo, Sartori, Alessandro A
Published in Frontiers in genetics (2013)
Published in Frontiers in genetics (2013)
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Journal Article
DNA end resection by CtIP and exonuclease 1 prevents genomic instability
Eid, Wassim, Steger, Martin, El-Shemerly, Mahmoud, Ferretti, Lorenza P, Peña-Diaz, Javier, König, Christiane, Valtorta, Emanuele, Sartori, Alessandro A, Ferrari, Stefano
Published in EMBO reports (01.12.2010)
Published in EMBO reports (01.12.2010)
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