First-in-Human, Multicenter, Phase I Dose-Escalation and Expansion Study of Anti-Mesothelin Antibody-Drug Conjugate Anetumab Ravtansine in Advanced or Metastatic Solid Tumors
Hassan, Raffit, Blumenschein, Jr, George R, Moore, Kathleen N, Santin, Alessandro D, Kindler, Hedy L, Nemunaitis, John J, Seward, Shelly M, Thomas, Anish, Kim, Stella K, Rajagopalan, Prabhu, Walter, Annette O, Laurent, Dirk, Childs, Barrett H, Sarapa, Nenad, Elbi, Cem, Bendell, Johanna C
Published in Journal of clinical oncology (01.06.2020)
Published in Journal of clinical oncology (01.06.2020)
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Evaluation of Tumor-Size Response Metrics to Predict Overall Survival in Western and Chinese Patients With First-Line Metastatic Colorectal Cancer
CLARET, Laurent, GUPTA, Manish, HAN, Kelong, JOSHI, Amita, SARAPA, Nenad, JING HE, POWELL, Bob, BRUNO, René
Published in Journal of clinical oncology (10.06.2013)
Published in Journal of clinical oncology (10.06.2013)
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Cardiac Safety Research Consortium: Can the thorough QT/QTc study be replaced by early QT assessment in routine clinical pharmacology studies? Scientific update and a research proposal for a path forward
Darpo, Borje, MD, PhD, Garnett, Christine, PharmD, Benson, Charles T., MD, PhD, Keirns, James, PhD, Leishman, Derek, PhD, Malik, Marek, MD, PhD, Mehrotra, Nitin, PhD, Prasad, Krishna, MD, FRCP, Riley, Steve, PharmD, PhD, Rodriguez, Ignacio, MD, Sager, Philip, MD, Sarapa, Nenad, MD, Wallis, Robert, PhD
Published in The American heart journal (01.09.2014)
Published in The American heart journal (01.09.2014)
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Novel Antibody Therapeutics Targeting Mesothelin In Solid Tumors
Zhao, Xiao-Yan, Subramanyam, Babu, Sarapa, Nenad, Golfier, Sven, Dinter, Harald
Published in Clinical cancer drugs (01.10.2016)
Published in Clinical cancer drugs (01.10.2016)
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The IQ-CSRC Prospective Clinical Phase 1 Study: "Can Early QT Assessment Using Exposure Response Analysis Replace the Thorough QT Study?"
Darpo, Borje, Sarapa, Nenad, Garnett, Christine, Benson, Charles, Dota, Corina, Ferber, Georg, Jarugula, Venkateswar, Johannesen, Lars, Keirns, James, Krudys, Kevin, Ortemann-Renon, Catherine, Riley, Steve, Rogers-Subramaniam, Danise, Stockbridge, Norman
Published in Annals of noninvasive electrocardiology (01.01.2014)
Published in Annals of noninvasive electrocardiology (01.01.2014)
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Lack of Effect of DX-619, a Novel Des-Fluoro(6)-Quinolone, on Glomerular Filtration Rate Measured by Serum Clearance of Cold Iohexol
SARAPA, Nenad, WICKREMASINGHA, Prachi, NANXIANG GE, WEITZMAN, Richard, FUELLHART, Merynda, YEN, Cindy, LLOYD-PARKS, Julia
Published in Antimicrobial Agents and Chemotherapy (01.06.2007)
Published in Antimicrobial Agents and Chemotherapy (01.06.2007)
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Comparison of QTinno, a fully automated electrocardiographic analysis program, to semiautomated electrocardiographic analysis methods in a drug safety study in healthy subjects
Sarapa, Nenad, MD, Gussak, Ihor, MD, PhD, Vajdic, Branislav, PhD, George, Samuel, MD, Hadzievski, Ljupco, PhD, Francom, Steven F., PhD, Kowey, Peter, MD, FRHS
Published in Journal of electrocardiology (01.07.2009)
Published in Journal of electrocardiology (01.07.2009)
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Automatic analysis of cardiac repolarization morphology using Gaussian mesa function modeling
Badilini, Fabio, PhD, Vaglio, Martino, MS, Dubois, Rémi, PhD, Roussel, Pierre, PhD, Sarapa, Nenad, MD, Denjoy, Isabelle, MD, Extramiana, Fabrice, MD, Maison-Blanche, Pierre, MD
Published in Journal of electrocardiology (01.11.2008)
Published in Journal of electrocardiology (01.11.2008)
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The application of accelerator mass spectrometry to absolute bioavailability studies in humans: simultaneous administration of an intravenous microdose of 14C-nelfinavir mesylate solution and oral nelfinavir to healthy volunteers
Sarapa, Nenad, Hsyu, Poe-Hirr, Lappin, Graham, Garner, Ronald Colin
Published in Journal of clinical pharmacology (01.10.2005)
Published in Journal of clinical pharmacology (01.10.2005)
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Unexpected pharmacokinetics of evofosfamide observed in phase III MAESTRO study
Higgins, Jack P., Sarapa, Nenad, Kim, Jason, Poma, Eric
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Abstract OT2-23-01: A Phase 1b/2a, open-label platform study to evaluate mirdametinib in combination with fulvestrant in ER+ metastatic breast cancers harboring MAPK-activating mutations
Rosen, Ezra Y., Patel, Payal, Sarapa, Nenad, Edris, Badreddin, Iasonos, Alexia, Jhaveri, Komal, Razavi, Pedram, Robson, Mark, Drilon, Alexander, Berger, Michael F., Solit, David B., Chandarlapaty, Sarat
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Pen-866, a miniature drug conjugate of a heat shock protein 90 (HSP90) ligand linked to SN38 for patients with advanced solid malignancies: Phase I and expansion cohort results
Falchook, Gerald Steven, Bendell, Johanna C., Ulahannan, Susanna Varkey, Sen, Shiraj, Vilimas, Rasa, Kriksciukaite, Kristina, Mei, Laura, Jerkovic, Goran, Sarapa, Nenad, Bilodeau, Mark, Bloss, Jeffrey, Thomas, Anish
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Safety and efficacy of anti-CD20 immunotoxin MT-3724 in relapsed/refractory (R/R) B-cell non-Hodgkin lymphoma (NHL) in a phase I study
Fanale, Michelle A., Hamlin, Paul A., Park, Steven I., Persky, Daniel Oscar, Higgins, Jack P., Burnett, Christine, Dabovic, Kristina, Poma, Eric, Sarapa, Nenad, Younes, Anas
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Clinical pharmacology characterization of RG7112, an MDM2 antagonist, in patients with advanced solid tumors
Patnaik, Amita, Tolcher, Anthony, Beeram, Murali, Nemunaitis, John, Weiss, Glen J., Bhalla, Kapil, Agrawal, Manish, Nichols, Gwen, Middleton, Steven, Beryozkina, Anna, Sarapa, Nenad, Peck, Richard, Zhi, Jianguo
Published in Cancer chemotherapy and pharmacology (01.09.2015)
Published in Cancer chemotherapy and pharmacology (01.09.2015)
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Abstract A095: Phase Ib study of anetumab ravtansine in combination with pemetrexed and cisplatin in patients with mesothelin-expressing epithelial mesothelioma or nonsquamous non-small cell lung cancer
Hassan, Raffit, Wang, Ding, Wrangle, John, Thomas, Anish, Byars, Angus, Asschert, Lianne, Atienza, Rolando, Rajagopalan, Prabhu, Walter, Annette, Zhang, Jun, Sarapa, Nenad, Kindler, Hedy
Published in Molecular cancer therapeutics (01.01.2018)
Published in Molecular cancer therapeutics (01.01.2018)
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Prediction of overall survival or progression free survival by disease control rate at week 8 is independent of ethnicity: Western versus Chinese patients with first-line non-small cell lung cancer treated with chemotherapy with or without bevacizumab
Claret, Laurent, Gupta, Manish, Han, Kelong, Joshi, Amita, Sarapa, Nenad, He, Jing, Powell, Bob, Bruno, René
Published in Journal of clinical pharmacology (01.03.2014)
Published in Journal of clinical pharmacology (01.03.2014)
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Evaluation of the Effect of 5 QT-Positive Drugs on the JTpeak Interval - An Analysis of ECGs From the IQ-CSRC Study
Darpo, Borje, Benson, Charles, Brown, Randy, Dota, Corina, Ferber, Georg, Ferry, Jim, Jarugula, Venkat, Keirns, James, Ortemann-Renon, Catherine, Pham, Thuan, Riley, Steve, Sarapa, Nenad, Ticktin, Mark, Zareba, Wojciech, Couderc, Jean-Philippe
Published in Journal of clinical pharmacology (01.01.2020)
Published in Journal of clinical pharmacology (01.01.2020)
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