Search Results - "Sarapa, N" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Results from the IQ-CSRC prospective study support replacement of the thorough QT study by QT assessment in the early clinical phase

Results from the IQ-CSRC prospective study support replacement of the thorough QT study by QT assessment in the early clinical phase

by Darpo, B, Benson, C, Dota, C, Ferber, G, Garnett, C, Green, C L, Jarugula, V, Johannesen, L, Keirns, J, Krudys, K, Liu, J, Ortemann-Renon, C, Riley, S, Sarapa, N, Smith, B, Stoltz, R R, Zhou, M, Stockbridge, N
Published in Clinical pharmacology and therapeutics (01.04.2015)

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Ritonavir 100 mg does not cause QTc prolongation in healthy subjects: a possible role as CYP3A inhibitor in thorough QTc studies

Ritonavir 100 mg does not cause QTc prolongation in healthy subjects: a possible role as CYP3A inhibitor in thorough QTc studies

by Sarapa, N, Nickens, D J, Raber, S R, Reynolds, R R, Amantea, M A
Published in Clinical pharmacology and therapeutics (01.01.2008)

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A phase I, randomized, open-label study of the multiple-dose pharmacokinetics of vemurafenib in patients with BRAF V600E mutation-positive metastatic melanoma

A phase I, randomized, open-label study of the multiple-dose pharmacokinetics of vemurafenib in patients with BRAF V600E mutation-positive metastatic melanoma

by Grippo, J F, Zhang, W, Heinzmann, D, Yang, K H, Wong, J, Joe, A K, Munster, P, Sarapa, N, Daud, A
Published in Cancer chemotherapy and pharmacology (01.01.2014)

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A phase I, randomized, open-label study of the multiple-dose pharmacokinetics of vemurafenib in patients with BRAFV600E mutation-positive metastatic melanoma

A phase I, randomized, open-label study of the multiple-dose pharmacokinetics of vemurafenib in patients with BRAFV600E mutation-positive metastatic melanoma

by Grippo, J. F., Zhang, W., Heinzmann, D., Yang, K. H., Wong, J., Joe, A. K., Munster, P., Sarapa, N., Daud, A.
Published in Cancer chemotherapy and pharmacology (2014)

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Electrocardiographic Identification of Drug-Induced QT Prolongation: Assessment by Different Recording and Measurement Methods

Electrocardiographic Identification of Drug-Induced QT Prolongation: Assessment by Different Recording and Measurement Methods

by Sarapa, Nenad, Morganroth, Joel, Couderc, Jean-Philippe, Francom, Steven F., Darpo, Borje, Fleishaker, Joseph C., McEnroe, Janet D., Chen, William T., Zareba, Wojciech, Moss, Arthur J.
Published in Annals of noninvasive electrocardiology (01.01.2004)

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Exploratory IND: a new regulatory strategy for early clinical drug development in the United States

Exploratory IND: a new regulatory strategy for early clinical drug development in the United States

by Sarapa, N
Published in Ernst Schering Research Foundation workshop (2007)

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461PFirst in human phase I/IIa study of PEN-866, a heat shock protein 90 (HSP90) ligand – SN38 conjugate for patients with advanced solid tumours: Phase I results

461PFirst in human phase I/IIa study of PEN-866, a heat shock protein 90 (HSP90) ligand – SN38 conjugate for patients with advanced solid tumours: Phase I results

by Bendell, J C, Falchook, G, Sen, S, Johnson, M L, Jerkovic, G, Sarapa, N, Vilimas, R, Kriksciukaite, K, Mei, L, Wooster, R, Bloss, J, Thomas, A
Published in Annals of oncology (01.10.2019)

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461P - First in human phase I/IIa study of PEN-866, a heat shock protein 90 (HSP90) ligand – SN38 conjugate for patients with advanced solid tumours: Phase I results

461P - First in human phase I/IIa study of PEN-866, a heat shock protein 90 (HSP90) ligand – SN38 conjugate for patients with advanced solid tumours: Phase I results

by Bendell, J.C., Falchook, G., Sen, S., Johnson, M.L., Jerkovic, G., Sarapa, N., Vilimas, R., Kriksciukaite, K., Mei, L., Wooster, R., Bloss, J., Thomas, A.
Published in Annals of oncology (01.10.2019)

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First in human phase I/IIa study of PEN-866, a heat shock protein 90 (HSP90) ligand – SN38 conjugate for patients with advanced solid tumours: Phase I results

First in human phase I/IIa study of PEN-866, a heat shock protein 90 (HSP90) ligand – SN38 conjugate for patients with advanced solid tumours: Phase I results

by Bendell, J.C., Falchook, G., Sen, S., Johnson, M.L., Jerkovic, G., Sarapa, N., Vilimas, R., Kriksciukaite, K., Mei, L., Wooster, R., Bloss, J., Thomas, A.
Published in Annals of oncology (01.10.2019)

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Cardiac Safety Research Consortium: Can the thorough QT/QTc study be replaced by early QT assessment in routine clinical pharmacology studies? Scientific update and a research proposal for a path forward

Cardiac Safety Research Consortium: Can the thorough QT/QTc study be replaced by early QT assessment in routine clinical pharmacology studies? Scientific update and a research proposal for a path forward

by Darpo, Borje, MD, PhD, Garnett, Christine, PharmD, Benson, Charles T., MD, PhD, Keirns, James, PhD, Leishman, Derek, PhD, Malik, Marek, MD, PhD, Mehrotra, Nitin, PhD, Prasad, Krishna, MD, FRCP, Riley, Steve, PharmD, PhD, Rodriguez, Ignacio, MD, Sager, Philip, MD, Sarapa, Nenad, MD, Wallis, Robert, PhD
Published in The American heart journal (01.09.2014)

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Are women more susceptible than men to drug‐induced QT prolongation? Concentration–QTc modelling in a phase 1 study with oral rac‐sotalol

Are women more susceptible than men to drug‐induced QT prolongation? Concentration–QTc modelling in a phase 1 study with oral rac‐sotalol

by Darpo, Borje, Karnad, Dilip R., Badilini, Fabio, Florian, Jeff, Garnett, Christine E, Kothari, Snehal, Panicker, Gopi Krishna, Sarapa, Nenad
Published in British journal of clinical pharmacology (01.03.2014)

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The IQ-CSRC Prospective Clinical Phase 1 Study: "Can Early QT Assessment Using Exposure Response Analysis Replace the Thorough QT Study?"

The IQ-CSRC Prospective Clinical Phase 1 Study: "Can Early QT Assessment Using Exposure Response Analysis Replace the Thorough QT Study?"

by Darpo, Borje, Sarapa, Nenad, Garnett, Christine, Benson, Charles, Dota, Corina, Ferber, Georg, Jarugula, Venkateswar, Johannesen, Lars, Keirns, James, Krudys, Kevin, Ortemann-Renon, Catherine, Riley, Steve, Rogers-Subramaniam, Danise, Stockbridge, Norman
Published in Annals of noninvasive electrocardiology (01.01.2014)

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Are women more susceptible than men to drug-induced QT prolongation? Concentration-QT c modelling in a phase 1 study with oral rac-sotalol

Are women more susceptible than men to drug-induced QT prolongation? Concentration-QT c modelling in a phase 1 study with oral rac-sotalol

by Darpo, B, Karnad, DR, Badilini, F, Florian, J, Garnett, CE, Kothari, S, Panicker, GK, Sarapa, N
Published in British journal of clinical pharmacology (2014)

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A phase I, randomized, open-label study of the multiple-dose pharmacokinetics of vemurafenib in patients with BRAF^sup V600E^ mutation-positive metastatic melanoma

A phase I, randomized, open-label study of the multiple-dose pharmacokinetics of vemurafenib in patients with BRAF^sup V600E^ mutation-positive metastatic melanoma

by Grippo, J F, Zhang, W, Heinzmann, D, Yang, K H, Wong, J, Joe, A K, Munster, P, Sarapa, N, Daud, A
Published in Cancer chemotherapy and pharmacology (01.01.2014)

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A phase I, randomized, open-label study of the multiple-dose pharmacokinetics of vemurafenib in patients with BRAF super(V600E) mutation-positive metastatic melanoma

A phase I, randomized, open-label study of the multiple-dose pharmacokinetics of vemurafenib in patients with BRAF super(V600E) mutation-positive metastatic melanoma

by Grippo, J F, Zhang, W, Heinzmann, D, Yang, KH, Wong, J, Joe, A K, Munster, P, Sarapa, N, Daud, A
Published in Cancer chemotherapy and pharmacology (01.01.2014)

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Digital 12-lead Holter in the assessment of drug effects on cardiac repolarization

Digital 12-lead Holter in the assessment of drug effects on cardiac repolarization

by Sarapa, Nenad
Published in Journal of electrocardiology (01.07.2005)

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Pharmacokinetics of intravenously administered digoxin in patients with edema

Pharmacokinetics of intravenously administered digoxin in patients with edema

by MACOLIC-SARINIC, V, VRHOVAC, B, PLAVSIC, F, HUIC, M, BAKRAN, I, FRANCETIC, I, GILJANOVIC, S, SARAPA, N
Published in Acta pharmaceutica (Zagreb, Croatia) (1995)

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Risk management and eligibility criteria for QTc assessment in patients with advanced cancer

Risk management and eligibility criteria for QTc assessment in patients with advanced cancer

by Sarapa, N., Huang, X., Varterasian, M., Fingert, H.
Published in Journal of clinical oncology (01.06.2005)

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Quantitative performance of E-Scribe warehouse in detecting quality issues with digital annotated ECG data from healthy subjects

Quantitative performance of E-Scribe warehouse in detecting quality issues with digital annotated ECG data from healthy subjects

by Sarapa, Nenad, Mortara, Justin L, Brown, Barry D, Isola, Lamberto, Badilini, Fabio
Published in Journal of clinical pharmacology (01.05.2008)

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Effect of rifampin on the pharmacokinetics of SU11248 in healthy volunteers

Effect of rifampin on the pharmacokinetics of SU11248 in healthy volunteers

by Bello, C., Houk, B., Sherman, L., Misbah, S., Sarapa, N., Smeraglia, J., Haung, X.
Published in Journal of clinical oncology (01.06.2005)

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