B10 Inclusion formation in mutant HTT exon 1 expressing human neuronal cells
Ghosh, Rhia, Wood-Kaczmar, Alison, Andre, Ralph, Kriston-Vizi, Janos, Ketteler, Robin, Cole, Sarah, Smith, Edward J, Bates, Gillian P, Tabrizi, Sarah J
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
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Journal Article
B49 Genetic modifiers of huntington’s disease progression
Moss, Davina J Hensman, Pardiñas, Antonio F, Flower, Michael, Miller, James, Lo, Kitty, Plagnol, Vincent, Holmans, Peter, Jones, Lesley, Langbehn, Douglas, Tabrizi, Sarah J
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
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Journal Article
D18 Brain network breakdown and pathophysiological correlates in huntington’s disease
McColgan, Peter, Razi, Adeel, Seunarine, Kiran K, Gregory, Sarah, Durr, Alexandra, Roos, Raymund AC, Scahill, Rachael I, Clark, Chris A, Rees, Geraint, Tabrizi, Sarah J
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
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J01 Effects of IONIS-HTTRX (RG6042) in patients with early huntington’s disease, results of the first htt-lowering drug trial
Tabrizi, Sarah J, Leavitt, Blair, Landwehrmeyer, Bernhard, Wild, Edward, Saft, Carsten, Barker, Roger, Craufurd, David, Rickards, Hugh, Rosser, Anne, Priller, Josef, Kordasiewicz, Holly, Czech, Christian, Swayze, Eric, Norris, Daniel A, Baumann, Tiffany, Gerlach, Irene, Schobel, Scott, Smith, Anne, Lane, Roger, Bennett, C Frank
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2018)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2018)
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Journal Article
Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients
Wild, Edward J, Boggio, Roberto, Langbehn, Douglas, Robertson, Nicola, Haider, Salman, Miller, James R.C, Zetterberg, Henrik, Leavitt, Blair R, Kuhn, Rainer, Tabrizi, Sarah J, Macdonald, Douglas, Weiss, Andreas
Published in The Journal of clinical investigation (01.05.2015)
Published in The Journal of clinical investigation (01.05.2015)
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B4 Detection of the aberrantly spliced exon 1 – intron 1 htt mRNA in HD patient post mortem brain tissue and fibroblast lines
Bates, Gillian P, Osborne, Georgiana F, Ali, Nadira, Benjamin, Agnesska C, Papadopoulou, Aikaterini S, Howland, David, Tabrizi, Sarah J, Faull, Richard LM, Myers, Richard H, Landles, Christian, Neueder, Andreas
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
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Journal Article
D21 Longitudinal compensation in the cognitive network in huntington’s disease
Gregory, Sarah, Klöppel, Stefan, Long, Jeffrey D, Razi, Adeel, Scheller, Elisa, Minkova, Lora, Dürr, Alexandra, Roos, Raymund AC, Leavitt, Blair R, Mills, James A, Stout, Julie, Scahill, Rachael I, Langbehn, Douglas R, Rees, Geraint, Tabrizi, Sarah J
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
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D20 Operationalising compensation over time in neurodegenerative disease
Gregory, Sarah, Long, Jeffrey D, Klöppel, Stefan, Razi, Adeel, Scheller, Elisa, Minkova, Lora, Papoutsi, Marina, Mills, James A, Stout, Julie, Scahill, Rachael I, Langbehn, Douglas R, Tabrizi, Sarah J, Rees, Geraint
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
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Journal Article
B15 Innate transcriptional dysregulation is associated with proinflammatory pathway activation in huntington’s disease myeloid cells
Andre, Ralph, Miller, James RC, Lo, Kitty K, Hensman Moss, Davina J, Träger, Ulrike, Stone, Timothy C, McErlean, Peter, Jones, Lesley, Holmans, Peter, Lavender, Paul, Plagnol, Vincent, Tabrizi, Sarah J
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
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Journal Article
B27 Abnormal bioenergetics in inclusion-containing mutant HTT exon 1 primary human neurons
Wood-Kaczmar, Alison, Ghosh, Rhia, Kriston-Vizi, Janos, Smith, Edward J, Chadwick, Wayne, Hargreaves, Iain P, Heales, Simon J, Abramov, Andrey Y, Cole, Sarah L, Ketteler, Robin, Bates, Gillian P, Andre, Ralph, Tabrizi, Sarah J
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
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Journal Article
Normal in vivo skeletal muscle oxidative metabolism in sporadic inclusion body myositis assessed by 31P-magnetic resonance spectroscopy
LODI, R, TAYLOR, D. J, TABRIZI, S. J, HILTON-JONES, D, SQUIER, M. V, SELLER, A, STYLES, P, SCHAPIRA, A. H. V
Published in Brain (London, England : 1878) (01.11.1998)
Published in Brain (London, England : 1878) (01.11.1998)
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Journal Article
N omenclature of genetic movement disorders: R ecommendations of the international P arkinson and movement disorder society task force
Marras, Connie, Lang, Anthony, van de Warrenburg, Bart P., Sue, Carolyn M., Tabrizi, Sarah J., Bertram, Lars, Mercimek‐Mahmutoglu, Saadet, Ebrahimi‐Fakhari, Darius, Warner, Thomas T., Durr, Alexandra, Assmann, Birgit, Lohmann, Katja, Kostic, Vladimir, Klein, Christine
Published in Movement disorders (01.04.2016)
Published in Movement disorders (01.04.2016)
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Large-scale brain network abnormalities in Huntington's disease revealed by structural covariance: Structural Covariance in Huntington's Disease
Minkova, Lora, Eickhoff, Simon B., Abdulkadir, Ahmed, Kaller, Christoph P., Peter, Jessica, Scheller, Elisa, Lahr, Jacob, Roos, Raymund A., Durr, Alexandra, Leavitt, Blair R., Tabrizi, Sarah J., Klöppel, Stefan
Published in Human brain mapping (01.01.2016)
Published in Human brain mapping (01.01.2016)
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Probabilistic classification learning with corrective feedback is selectively impaired in early Huntingtonas diseaseaEvidence for the role of the striatum in learning with feedback
Holl, Anna K, Wilkinson, Leonora, Tabrizi, Sarah J, Painold, Annamaria, Jahanshahi, Marjan
Published in Neuropsychologia (01.07.2012)
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Published in Neuropsychologia (01.07.2012)
Journal Article
B17 Blood transcriptome replicates dysregulation found in human huntington’s disease brain and shares an immune signature with alzheimer’s disease
Flower, Michael, Moss, Davina Hensman, Lo, Kitty K, Miller, James, Omen, Gert-Jan van, ’t Hoen, Peter AC, Stone, Timothy, Guinee, Amelia, Langbehn, Doug, Jones, Lesley, Plagnol, Vincent, van Roon-Mom, Willeke MC, Holmans, Peter, Tabrizi, Sarah J
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
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Journal Article
D22 Compensation in preclinical huntington’s disease: evidence from the track-on HD study
Gregory, Sarah, Klöppel, Stefan, Scheller, Elisa, Minkova, Lora, Razi, Adeel, Durr, Alexandra, Roos, Raymund AC, Leavitt, Blair R, Papoutsi, Marina, Bernhard Landwehrmeyer, G, Reilmann, Ralf, Borowsky, Beth, Johnson, Hans, Mills, James A, Owen, Gail, Stout, Julie, Scahill, Rachael I, Long, Jeffrey D, Rees, Geraint, Tabrizi, Sarah J
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
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Journal Article
B48 DNA repair pathways as a common genetic mechanism modulating the age at onset in polyglutamine diseases
Bettencourt, Conceição, Moss, Davina Hensman, Flower, Michael, Wiethoff, Sarah, Brice, Alexis, Goizet, Cyril, Stevanin, Giovanni, Koutsis, Georgios, Karadima, Georgia, Panas, Marios, Yescas-Gómez, Petra, García-Velázquez, Lizbeth Esmeralda, Alonso-Vilatela, María Elisa, Lima, Manuela, Raposo, Mafalda, Traynor, Bryan, Sweeney, Mary, Wood, Nicholas, Giunti, Paola, Durr, Alexandra, Holmans, Peter, Houlden, Henry, Tabrizi, Sarah J, Jones, Lesley
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
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Journal Article
Harnessing Immune Alterations in Neurodegenerative Diseases
Bjoerkqvist, Maria, Wild, Edward J, Tabrizi, Sarah J
Published in Neuron (Cambridge, Mass.) (15.10.2009)
Published in Neuron (Cambridge, Mass.) (15.10.2009)
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Journal Article
A SNP in the HTT promoter alters NF-[kappa]B binding and is a bidirectional genetic modifier of Huntington disease
Becanovic, Kristina, Nørremølle, Anne, Neal, Scott J, Kay, Chris, Collins, Jennifer A, Arenillas, David, Lilja, Tobias, Gaudenzi, Giulia, Manoharan, Shiana, Doty, Crystal N, Beck, Jessalyn, Lahiri, Nayana, Portales-casamar, Elodie, Warby, Simon C, Connolly, Colúm, De Souza, Rebecca A G, Tabrizi, Sarah J, Hermanson, Ola, Langbehn, Douglas R, Hayden, Michael R, Wasserman, Wyeth W, Leavitt, Blair R
Published in Nature neuroscience (01.06.2015)
Published in Nature neuroscience (01.06.2015)
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Journal Article
B24 Assessment of immune system activation status during the course of disease in huntington’s disease mouse model
Pido-Lopez, Jeffrey, Andre, Ralph, Benjamin, Agnesska, Franklin, Sophie A, Tabrizi, Sarah J, Bates, Gillian P
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2016)
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