Prevalent, Dynamic, and Conserved R-Loop Structures Associate with Specific Epigenomic Signatures in Mammals
Sanz, Lionel A., Hartono, Stella R., Lim, Yoong Wearn, Steyaert, Sandra, Rajpurkar, Aparna, Ginno, Paul A., Xu, Xiaoqin, Chédin, Frédéric
Published in Molecular cell (07.07.2016)
Published in Molecular cell (07.07.2016)
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Journal Article
Recognition of RNA by the S9.6 antibody creates pervasive artifacts when imaging RNA:DNA hybrids
Smolka, John A, Sanz, Lionel A, Hartono, Stella R, Chédin, Frédéric
Published in The Journal of cell biology (07.06.2021)
Published in The Journal of cell biology (07.06.2021)
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Journal Article
Transcription-associated R-loop formation across the human FMR1 CGG-repeat region
Loomis, Erick W, Sanz, Lionel A, Chédin, Frédéric, Hagerman, Paul J
Published in PLoS genetics (01.04.2014)
Published in PLoS genetics (01.04.2014)
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Journal Article
DNA Topoisomerase I differentially modulates R-loops across the human genome
Manzo, Stefano G, Hartono, Stella R, Sanz, Lionel A, Marinello, Jessica, De Biasi, Sara, Cossarizza, Andrea, Capranico, Giovanni, Chedin, Frederic
Published in Genome Biology (30.07.2018)
Published in Genome Biology (30.07.2018)
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Journal Article
Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage
Stork, Caroline Townsend, Bocek, Michael, Crossley, Madzia P, Sollier, Julie, Sanz, Lionel A, Chédin, Frédéric, Swigut, Tomek, Cimprich, Karlene A
Published in eLife (23.08.2016)
Published in eLife (23.08.2016)
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Journal Article
Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome
Lim, Yoong Wearn, Sanz, Lionel A, Xu, Xiaoqin, Hartono, Stella R, Chédin, Frédéric
Published in eLife (16.07.2015)
Published in eLife (16.07.2015)
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Journal Article
RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2
Alecki, Célia, Chiwara, Victoria, Sanz, Lionel A, Grau, Daniel, Arias Pérez, Osvaldo, Boulier, Elodie L, Armache, Karim-Jean, Chédin, Frédéric, Francis, Nicole J
Published in Nature communications (14.04.2020)
Published in Nature communications (14.04.2020)
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Journal Article
EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos
Auclair, Ghislain, Borgel, Julie, Sanz, Lionel A, Vallet, Judith, Guibert, Sylvain, Dumas, Michael, Cavelier, Patricia, Girardot, Michael, Forné, Thierry, Feil, Robert, Weber, Michael
Published in Genome research (01.02.2016)
Published in Genome research (01.02.2016)
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Journal Article
A mono-allelic bivalent chromatin domain controls tissue-specific imprinting at Grb10
Sanz, Lionel A, Chamberlain, Stormy, Sabourin, Jean-Charles, Henckel, Amandine, Magnuson, Terry, Hugnot, Jean-Philippe, Feil, Robert, Arnaud, Philippe
Published in The EMBO journal (08.10.2008)
Published in The EMBO journal (08.10.2008)
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Journal Article
Best practices for the visualization, mapping, and manipulation of R‐loops
Chédin, Frédéric, Hartono, Stella R, Sanz, Lionel A, Vanoosthuyse, Vincent
Published in The EMBO journal (15.02.2021)
Published in The EMBO journal (15.02.2021)
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Journal Article
The Air Noncoding RNA Epigenetically Silences Transcription by Targeting G9a to Chromatin
Nagano, Takashi, Mitchell, Jennifer A., Sanz, Lionel A., Pauler, Florian M., Ferguson-Smith, Anne C., Feil, Robert, Fraser, Peter
Published in Science (American Association for the Advancement of Science) (12.12.2008)
Published in Science (American Association for the Advancement of Science) (12.12.2008)
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Journal Article
Mapping R-Loops and RNA:DNA Hybrids with S9.6-Based Immunoprecipitation Methods
Sanz, Lionel A., Castillo-Guzman, Daisy, Chédin, Frédéric
Published in Journal of visualized experiments (24.08.2021)
Published in Journal of visualized experiments (24.08.2021)
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Journal Article
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation
Richard, Patricia, Feng, Shuang, Tsai, Yueh-Lin, Li, Wencheng, Rinchetti, Paola, Muhith, Ubayed, Irizarry-Cole, Juan, Stolz, Katharine, Sanz, Lionel A., Hartono, Stella, Hoque, Mainul, Tadesse, Saba, Seitz, Hervé, Lotti, Francesco, Hirano, Michio, Chédin, Frédéric, Tian, Bin, Manley, James L.
Published in Autophagy (03.08.2021)
Published in Autophagy (03.08.2021)
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Journal Article
CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells
Kumar, Sushil, Zeng, Zexian, Bagati, Archis, Tay, Rong En, Sanz, Lionel A, Hartono, Stella R, Ito, Yoshinaga, Abderazzaq, Fieda, Hatchi, Elodie, Jiang, Peng, Cartwright, Adam N R, Olawoyin, Olamide, Mathewson, Nathan D, Pyrdol, Jason W, Li, Mamie Z, Doench, John G, Booker, Matthew A, Tolstorukov, Michael Y, Elledge, Stephen J, Chédin, Frédéric, Liu, X Shirley, Wucherpfennig, Kai W
Published in Cancer discovery (01.08.2021)
Published in Cancer discovery (01.08.2021)
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Journal Article
PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma
Giuliani, Virginia, Miller, Meredith A, Liu, Chiu-Yi, Hartono, Stella R, Class, Caleb A, Bristow, Christopher A, Suzuki, Erika, Sanz, Lionel A, Gao, Guang, Gay, Jason P, Feng, Ningping, Rose, Johnathon L, Tomihara, Hideo, Daniele, Joseph R, Peoples, Michael D, Bardenhagen, Jennifer P, Geck Do, Mary K, Chang, Qing E, Vangamudi, Bhavatarini, Vellano, Christopher, Ying, Haoqiang, Deem, Angela K, Do, Kim-Anh, Genovese, Giannicola, Marszalek, Joseph R, Kovacs, Jeffrey J, Kim, Michael, Fleming, Jason B, Guccione, Ernesto, Viale, Andrea, Maitra, Anirban, Emilia Di Francesco, M, Yap, Timothy A, Jones, Philip, Draetta, Giulio, Carugo, Alessandro, Chedin, Frederic, Heffernan, Timothy P
Published in Nature communications (30.07.2021)
Published in Nature communications (30.07.2021)
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