Estrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status
Di Leva, Gianpiero, Piovan, Claudia, Gasparini, Pierluigi, Ngankeu, Apollinaire, Taccioli, Cristian, Briskin, Daniel, Cheung, Douglas G, Bolon, Brad, Anderlucci, Laura, Alder, Hansjuerg, Nuovo, Gerard, Li, Meng, Iorio, Marilena V, Galasso, Marco, Santhanam, Ramasamy, Ramasamy, Santhanam, Marcucci, Guido, Perrotti, Danilo, Powell, Kimerly A, Bratasz, Anna, Garofalo, Michela, Nephew, Kenneth P, Croce, Carlo M
Published in PLoS genetics (01.03.2013)
Published in PLoS genetics (01.03.2013)
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MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response
Fabbri, Muller, Paone, Alessio, Calore, Federica, Galli, Roberta, Gaudio, Eugenio, Santhanam, Ramasamy, Lovat, Francesca, Fadda, Paolo, Mao, Charlene, Nuovo, Gerard J, Zanesi, Nicola, Crawford, Melissa, Ozer, Gulcin H, Wernicke, Dorothee, Alder, Hansjuerg, Caligiuri, Michael A, Nana-Sinkam, Patrick, Perrotti, Danilo, Croce, Carlo M
Published in Proceedings of the National Academy of Sciences - PNAS (31.07.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (31.07.2012)
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Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia
Ranganathan, Parvathi, Yu, Xueyan, Na, Caroline, Santhanam, Ramasamy, Shacham, Sharon, Kauffman, Michael, Walker, Alison, Klisovic, Rebecca, Blum, William, Caligiuri, Michael, Croce, Carlo M., Marcucci, Guido, Garzon, Ramiro
Published in Blood (30.08.2012)
Published in Blood (30.08.2012)
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Targeted Delivery of microRNA-29b by Transferrin-Conjugated Anionic Lipopolyplex Nanoparticles: A Novel Therapeutic Strategy in Acute Myeloid Leukemia
XIAOMENG HUANG, SCHWIND, Sebastian, BLUM, William, PERROTTI, Danilo, BYRD, John C, BLOOMFIELD, Clara D, CALIGIURI, Michael A, LEE, Robert J, GARZON, Ramiro, MUTHUSAMY, Natarajan, LEE, Ly James, MARCUCCI, Guido, BO YU, SANTHANAM, Ramasamy, HONGYAN WANG, HOELLERBAUER, Pia, MIMS, Alice, KLISOVIC, Rebecca, WALKER, Alison R, CHAN, Kenneth K
Published in Clinical cancer research (01.05.2013)
Published in Clinical cancer research (01.05.2013)
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miR-328 Functions as an RNA Decoy to Modulate hnRNP E2 Regulation of mRNA Translation in Leukemic Blasts
Eiring, Anna M., Harb, Jason G., Neviani, Paolo, Garton, Christopher, Oaks, Joshua J., Spizzo, Riccardo, Liu, Shujun, Schwind, Sebastian, Santhanam, Ramasamy, Hickey, Christopher J., Becker, Heiko, Chandler, Jason C., Andino, Raul, Cortes, Jorge, Hokland, Peter, Huettner, Claudia S., Bhatia, Ravi, Roy, Denis C., Liebhaber, Stephen A., Caligiuri, Michael A., Marcucci, Guido, Garzon, Ramiro, Croce, Carlo M., Calin, George A., Perrotti, Danilo
Published in Cell (05.03.2010)
Published in Cell (05.03.2010)
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Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias
Walker, Christopher J., Oaks, Joshua J., Santhanam, Ramasamy, Neviani, Paolo, Harb, Jason G., Ferenchak, Gregory, Ellis, Justin J., Landesman, Yosef, Eisfeld, Ann-Kathrin, Gabrail, Nash Y., Smith, Carrie L., Caligiuri, Michael A., Hokland, Peter, Roy, Denis Claude, Reid, Alistair, Milojkovic, Dragana, Goldman, John M., Apperley, Jane, Garzon, Ramiro, Marcucci, Guido, Shacham, Sharon, Kauffman, Michael G., Perrotti, Danilo
Published in Blood (24.10.2013)
Published in Blood (24.10.2013)
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Inhibition of BET Proteins Regulates Fcγ Receptor Function and Reduces Inflammation in Rheumatoid Arthritis
Shankar, Divya, Merchand-Reyes, Giovanna, Buteyn, Nathaniel J, Santhanam, Ramasamy, Fang, Huiqing, Kumar, Krishan, Mo, Xiaokui, Ganesan, Latha P, Jarjour, Wael, Butchar, Jonathan P, Tridandapani, Susheela
Published in International journal of molecular sciences (01.04.2023)
Published in International journal of molecular sciences (01.04.2023)
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Activation of the Intracellular Pattern Recognition Receptor NOD2 Promotes Acute Myeloid Leukemia (AML) Cell Apoptosis and Provides a Survival Advantage in an Animal Model of AML
Buteyn, Nathaniel J, Santhanam, Ramasamy, Merchand-Reyes, Giovanna, Murugesan, Rakesh A, Dettorre, Gino M, Byrd, John C, Sarkar, Anasuya, Vasu, Sumithira, Mundy-Bosse, Bethany L, Butchar, Jonathan P, Tridandapani, Susheela
Published in The Journal of immunology (1950) (01.04.2020)
Published in The Journal of immunology (1950) (01.04.2020)
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Aberrant Overexpression of IL-15 Initiates Large Granular Lymphocyte Leukemia through Chromosomal Instability and DNA Hypermethylation
Mishra, Anjali, Liu, Shujun, Sams, Gregory H., Curphey, Douglas P., Santhanam, Ramasamy, Rush, Laura J., Schaefer, Deanna, Falkenberg, Lauren G., Sullivan, Laura, Jaroncyk, Laura, Yang, Xiaojuan, Fisk, Harold, Wu, Lai-Chu, Hickey, Christopher, Chandler, Jason C., Wu, Yue-Zhong, Heerema, Nyla A., Chan, Kenneth K., Perrotti, Danilo, Zhang, Jianying, Porcu, Pierluigi, Racke, Frederick K., Garzon, Ramiro, Lee, Robert J., Marcucci, Guido, Caligiuri, Michael A.
Published in Cancer cell (13.11.2012)
Published in Cancer cell (13.11.2012)
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Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies
Oaks, Joshua J., Santhanam, Ramasamy, Walker, Christopher J., Roof, Steve, Harb, Jason G., Ferenchak, Greg, Eisfeld, Ann-Kathrin, Van Brocklyn, James R., Briesewitz, Roger, Saddoughi, Sahar A., Nagata, Kyosuke, Bittman, Robert, Caligiuri, Michael A., Abdel-Wahab, Omar, Levine, Ross, Arlinghaus, Ralph B., Quintas-Cardama, Alfonso, Goldman, John M., Apperley, Jane, Reid, Alistair, Milojkovic, Dragana, Ziolo, Mark T., Marcucci, Guido, Ogretmen, Besim, Neviani, Paolo, Perrotti, Danilo
Published in Blood (12.09.2013)
Published in Blood (12.09.2013)
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Regulation of acute graft-versus-host disease by microRNA-155
Ranganathan, Parvathi, Heaphy, Catherine E.A., Costinean, Stefan, Stauffer, Nicole, Na, Caroline, Hamadani, Mehdi, Santhanam, Ramasamy, Mao, Charlene, Taylor, Patricia A., Sandhu, Sukhinder, He, Gang, Shana'ah, Arwa, Nuovo, Gerard J., Lagana, Alessandro, Cascione, Luciano, Obad, Susanna, Broom, Oliver, Kauppinen, Sakari, Byrd, John C., Caligiuri, Michael, Perrotti, Danilo, Hadley, Gregg A., Marcucci, Guido, Devine, Steven M., Blazar, Bruce R., Croce, Carlo M., Garzon, Ramiro
Published in Blood (17.05.2012)
Published in Blood (17.05.2012)
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Active Hexose-Correlated Compound Shows Direct and Indirect Effects against Chronic Lymphocytic Leukemia
Merchand-Reyes, Giovanna, Santhanam, Ramasamy, Valencia-Pena, Maria L, Kumar, Krishan, Mo, Xiaokui, Belay, Tesfaye, Woyach, Jennifer A, Mundy-Bosse, Bethany, Tridandapani, Susheela, Butchar, Jonathan P
Published in Nutrients (01.12.2023)
Published in Nutrients (01.12.2023)
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FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia
Neviani, Paolo, Santhanam, Ramasamy, Oaks, Joshua J, Eiring, Anna M, Notari, Mario, Blaser, Bradley W, Liu, Shujun, Trotta, Rossana, Muthusamy, Natarajan, Gambacorti-Passerini, Carlo, Druker, Brian J, Cortes, Jorge, Marcucci, Guido, Chen, Ching-Shih, Verrills, Nicole M, Roy, Denis C, Caligiuri, Michael A, Bloomfield, Clara D, Byrd, John C, Perrotti, Danilo
Published in The Journal of clinical investigation (01.09.2007)
Published in The Journal of clinical investigation (01.09.2007)
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Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis
Wei, Guo, Srinivasan, Ruchika, Cantemir-Stone, Carmen Z., Sharma, Sudarshana M., Santhanam, Ramasamy, Weinstein, Michael, Muthusamy, Natarajan, Man, Albert K., Oshima, Robert G., Leone, Gustavo, Ostrowski, Michael C.
Published in Blood (30.07.2009)
Published in Blood (30.07.2009)
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Clinical and pharmacodynamic activity of bortezomib and decitabine in acute myeloid leukemia
Blum, William, Schwind, Sebastian, Tarighat, Somayeh S., Geyer, Susan, Eisfeld, Ann-Kathrin, Whitman, Susan, Walker, Alison, Klisovic, Rebecca, Byrd, John C., Santhanam, Ramasamy, Wang, Hongyan, Curfman, John P., Devine, Steven M., Jacob, Samson, Garr, Celia, Kefauver, Cheryl, Perrotti, Danilo, Chan, Kenneth K., Bloomfield, Clara D., Caligiuri, Michael A., Grever, Michael R., Garzon, Ramiro, Marcucci, Guido
Published in Blood (21.06.2012)
Published in Blood (21.06.2012)
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The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein
Neviani, Paolo, Santhanam, Ramasamy, Trotta, Rossana, Notari, Mario, Blaser, Bradley W., Liu, Shujun, Mao, Hsiaoyin, Chang, Ji Suk, Galietta, Annamaria, Uttam, Ashwin, Roy, Denis C., Valtieri, Mauro, Bruner-Klisovic, Rebecca, Caligiuri, Michael A., Bloomfield, Clara D., Marcucci, Guido, Perrotti, Danilo
Published in Cancer cell (01.11.2005)
Published in Cancer cell (01.11.2005)
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Anti-leukemic effects of all-trans retinoic acid in combination with Daratumumab in acute myeloid leukemia
Buteyn, Nathaniel J, Fatehchand, Kavin, Santhanam, Ramasamy, Fang, Huiqing, Dettorre, Gino M, Gautam, Shalini, Harrington, Bonnie K, Henderson, Sally E, Merchand-Reyes, Giovanna, Mo, Xiaokui, Benson, Don M, Carson, 3rd, William E, Vasu, Sumithira, Byrd, John C, Butchar, Jonathan P, Tridandapani, Susheela
Published in International immunology (24.07.2018)
Published in International immunology (24.07.2018)
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NOD2 activation enhances macrophage Fcγ receptor function and may increase the efficacy of antibody therapy
Merchand-Reyes, Giovanna, Bull, Mikayla F, Santhanam, Ramasamy, Valencia-Pena, Maria L, Murugesan, Rakesh A, Chordia, Aadesh, Mo, Xiaokui-Molly, Robledo-Avila, Frank H, Ruiz-Rosado, Juan De Dios, Carson, 3rd, William Edgar, Byrd, John C, Woyach, Jennifer A, Tridandapani, Susheela, Butchar, Jonathan P
Published in Frontiers in immunology (2024)
Published in Frontiers in immunology (2024)
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Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A
Salas, Arelis, Ponnusamy, Suriyan, Senkal, Can E., Meyers-Needham, Marisa, Selvam, Shanmugam Panneer, Saddoughi, Sahar A., Apohan, Elif, Sentelle, R. David, Smith, Charles, Gault, Christopher R., Obeid, Lina M., El-Shewy, Hesham M., Oaks, Joshua, Santhanam, Ramasamy, Marcucci, Guido, Baran, Yusuf, Mahajan, Sandeep, Fernandes, Daniel, Stuart, Robert, Perrotti, Danilo, Ogretmen, Besim
Published in Blood (02.06.2011)
Published in Blood (02.06.2011)
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