Tau - an inhibitor of deacetylase HDAC6 function
Perez, Mar, Santa-Maria, Ismael, de Barreda, Elena Gomez, Zhu, Xiongwei, Cuadros, Raquel, Cabrero, Jose Roman, Sanchez-Madrid, Francisco, Dawson, Hana N, Vitek, Michael P, Perry, George, Smith, Mark A, Avila, Jesus
Published in Journal of neurochemistry (01.06.2009)
Published in Journal of neurochemistry (01.06.2009)
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Journal Article
Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease
Mondragón-Rodríguez, Siddhartha, Basurto-Islas, Gustavo, Santa-Maria, Ismael, Mena, Raúl, Binder, Lester I., Avila, Jesús, Smith, Mark A., Perry, George, García-Sierra, Francisco
Published in International journal of experimental pathology (01.04.2008)
Published in International journal of experimental pathology (01.04.2008)
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Journal Article
Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau
Santa-Maria, Ismael, Alaniz, Maria E, Renwick, Neil, Cela, Carolina, Fulga, Tudor A, Van Vactor, David, Tuschl, Thomas, Clark, Lorraine N, Shelanski, Michael L, McCabe, Brian D, Crary, John F
Published in The Journal of clinical investigation (01.02.2015)
Published in The Journal of clinical investigation (01.02.2015)
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Journal Article
Effects of Eph/ephrin signalling and human Alzheimer's disease-associated EphA1 on Drosophila behaviour and neurophysiology
Buhl, Edgar, Kim, Yoon A., Parsons, Tom, Zhu, Bangfu, Santa-Maria, Ismael, Lefort, Roger, Hodge, James J.L.
Published in Neurobiology of disease (01.08.2022)
Published in Neurobiology of disease (01.08.2022)
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Journal Article
Paired Helical Filaments from Alzheimer Disease Brain Induce Intracellular Accumulation of Tau Protein in Aggresomes
Santa-Maria, Ismael, Varghese, Merina, Ksiȩżak-Reding, Hanna, Dzhun, Anastasiya, Wang, Jun, Pasinetti, Giulio M.
Published in The Journal of biological chemistry (08.06.2012)
Published in The Journal of biological chemistry (08.06.2012)
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Journal Article
Retromer deficiency in Tauopathy models enhances the truncation and toxicity of Tau
Asadzadeh, Jamshid, Ruchti, Evelyne, Jiao, Wei, Limoni, Greta, MacLachlan, Catherine, Small, Scott A., Knott, Graham, Santa-Maria, Ismael, McCabe, Brian D.
Published in Nature communications (27.08.2022)
Published in Nature communications (27.08.2022)
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Journal Article
PAC1 receptor-mediated clearance of tau in postsynaptic compartments attenuates tau pathology in mouse brain
Schaler, Ari W, Runyan, Avery M, Clelland, Catherine L, Sydney, Eric J, Fowler, Stephanie L, Figueroa, Helen Y, Shioda, Seiji, Santa-Maria, Ismael, Duff, Karen E, Myeku, Natura
Published in Science translational medicine (26.05.2021)
Published in Science translational medicine (26.05.2021)
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Journal Article
Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors
Sproul, Andrew A, Jacob, Samson, Pre, Deborah, Kim, Soong Ho, Nestor, Michael W, Navarro-Sobrino, Miriam, Santa-Maria, Ismael, Zimmer, Matthew, Aubry, Soline, Steele, John W, Kahler, David J, Dranovsky, Alex, Arancio, Ottavio, Crary, John F, Gandy, Sam, Noggle, Scott A
Published in PloS one (08.01.2014)
Published in PloS one (08.01.2014)
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Journal Article
The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms
Felsky, Daniel, Santa-Maria, Ismael, Cosacak, Mehmet Ilyas, French, Leon, Schneider, Julie A., Bennett, David A., De Jager, Philip L., Kizil, Caghan, Tosto, Giuseppe
Published in Neurobiology of disease (01.01.2023)
Published in Neurobiology of disease (01.01.2023)
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Journal Article
Development of a grape seed polyphenolic extract with anti-oligomeric activity as a novel treatment in progressive supranuclear palsy and other tauopathies
Pasinetti, Giulio Maria, Ksiezak-Reding, Hanna, Santa-Maria, Ismael, Wang, Jun, Ho, Lap
Published in Journal of neurochemistry (01.09.2010)
Published in Journal of neurochemistry (01.09.2010)
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Journal Article
Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial Lcn2/Slc22a17 signaling in Alzheimer’s disease
Siddiqui, Tohid, Cosacak, Mehmet Ilyas, Popova, Stanislava, Bhattarai, Prabesh, Yilmaz, Elanur, Lee, Annie J., Min, Yuhao, Wang, Xue, Allen, Mariet, İş, Özkan, Atasavum, Zeynep Tansu, Rodriguez-Muela, Natalia, Vardarajan, Badri N., Flaherty, Delaney, Teich, Andrew F., Santa-Maria, Ismael, Freudenberg, Uwe, Werner, Carsten, Tosto, Giuseppe, Mayeux, Richard, Ertekin-Taner, Nilüfer, Kizil, Caghan
Published in npj Regenerative medicine (10.07.2023)
Published in npj Regenerative medicine (10.07.2023)
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Journal Article
Binding of Hsp90 to Tau Promotes a Conformational Change and Aggregation of Tau Protein
Tortosa, Elena, Santa-Maria, Ismael, Moreno, Francisco, Lim, Filip, Perez, Mar, Avila, Jesús
Published in Journal of Alzheimer's disease (01.01.2009)
Published in Journal of Alzheimer's disease (01.01.2009)
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Journal Article
Extracellular Tau Paired Helical Filaments Differentially Affect Tau Pathogenic Mechanisms in Mitotic and Post-Mitotic Cells: Implications for Mechanisms of Tau Propagation in the Brain
Varghese, Merina, Santa-Maria, Ismael, Ho, Lap, Ward, Libby, Yemul, Shrishailam, Dubner, Lauren, Księżak-Reding, Hanna, Pasinetti, Giulio Maria
Published in Journal of Alzheimer's disease (06.09.2016)
Published in Journal of Alzheimer's disease (06.09.2016)
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Journal Article
role of the VQIVYK peptide in tau protein phosphorylation
Perez, Mar, Santa-María, Ismael, Tortosa, Elena, Cuadros, Raquel, Valle, Mercedes del, Hernández, Felix, Moreno, Francisco J, Avila, Jesús
Published in Journal of neurochemistry (01.11.2007)
Published in Journal of neurochemistry (01.11.2007)
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Journal Article